Clinical trials: Ovarian Hyperstimulation
Female Infertility Due to Nonimplantation of Ovum, Complications Associated With Artificial Fertilization
Comparing Ovarian Stimulation for Assisted Reproduction With Two Different Forms of Pituitary Suppression
The purpose of this study is to assess the non-inferiority of a multidose GnRH antagonist (cetrorelix) regimen to a GnRH agonist (triptorelin) long protocol in young infertile women undergoing ovarian stimulation with Pergoveris…
- Trial name
- Pergoveris (NCT01565265)
- Testing
- Pergoveris in long protocol with GnRH agonist, Pergoveris in GnRH antagonist protocol
- Where
- Switzerland
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Ovarian Stimulation
Antagonist/Letrozole in Poor Responders
Failure to respond to controlled ovarian hyperstimulation (COH) is still a major concern in assisted reproduction and there is no consensus on the ovarian stimulation choice regime for poor responders.
- Trial name
- NCT00823004
- Testing
- letrozole, oral contraceptive (Marvelone), GnRH agonist (buserelin)
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yazd Research & Clinical Center for Infertility
Stimulation in the Ovary
A Comparative Study of Two Patterns of Controlled Ovarian Hyperstimulation in Mid Follicular Phase or Early Luteal Phase for Egg Donors
The purpose of this study is to determine the efficacy and safety of two new patterns of controlled ovarian hyperstimulation (defined as total number of picked up eggs).
- Trial name
- NCT01385332
- Testing
- Early luteal phase, Late follicular phase -COH-
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Infertility, Female, Fertility Disorders
Comparison of Two PPOS Models for Pituitary Suppression
The scarcity of evidence regarding the interchangeable use of different progestogens poses challenges, particularly in international egg donation and fertility preservation programs where standardizing protocols is crucial for…
- Trial name
- NCT06304220
- Testing
- Cerazet
- Where
- Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- NextFertility
Ovarian Hyperstimulation Syndrome
The Effect of Human Albumin Infusion on VEGF Levels in Women at Risk for Ovarian Hyperstimulation Syndrome
This research study was designed to look at the effect of human albumin transfusion on circulating levels of Vascular Endothelial Derived Growth Factor (VEGF), a protein that is believed to be responsible for the syndrome of…
- Trial name
- NCT00617864
- Testing
- Human Albumin Infusion, Saline Infusion
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Infertility
Circadian Variation in Serum-progesterone Levels Following Controlled Ovarian Hyperstimulation.
The aim of the study is to investigate the circadian variation in serum-progesterone in women undergoing controlled ovarian stimulation.
- Trial name
- NCT02673034
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Regionshospitalet Viborg, Skive
Ovarian Hyperstimulation Syndrome, Effects of Gonadotropin
GnRH Antagonist for Treatment of Early Ovarian Hyperstimulation Syndrome
The aim of this study is to analyze the effectiveness of GnRh antagonist in the treatment of early ovarian hyperstimulation syndrome.
- Conditions
- Ovarian Hyperstimulation Syndrome, Effects of Gonadotropin, Oocyte Maturation
- Trial name
- NCT01268761
- Testing
- GnRH antagonist (Cetrorelix)
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Endometrial Receptivity, Ovarian Hyperstimulation Syndrome
Gene Expression Profile After Gonadotropin Releasing Hormone (GnRH) Agonist Trigger of Oocyte Maturation
The purpose of this study is to compare gene expression profiles in endometrial biopsies during the window of implantation after triggers of oocyte maturation using GnRH agonist or hCG and compared with their natural cycles in…
- Trial name
- NCT01606709
- Testing
- GnRH agonist, hCG
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- UConn Health
Polycystic Ovary Syndrome, Ovarian Hyperstimulation Syndrome
The Four Methods of Ovarian Stimulation in Patients With Polycystic Ovarian Syndrome
This study is a randomized controlled clinical trial to compare the pregnancy outcomes of mild and minimal stimulation in infertile women with polycystic ovarian syndrome.
- Trial name
- NCT03876145
- Testing
- Minimal ovarian stimulation
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Royan Institute
IVF Cycle, Ovarian Stimulation
Efficacy and Safety of Medication Used to Stimulate Ovulation
Individuals undergoing In Vitro Fertilization must undergo controlled ovarian hyperstimulation (COH) to produce enough quality eggs for fertility treatment.
- Conditions
- IVF Cycle, Ovarian Stimulation, Egg Retrieval, Pregnancy
- Trial name
- NCT02715336
- Testing
- Ovulation induction with hCG and Lupron (GnRH agonist)
- Where
- Canada
- Volunteers
- 666 people, healthy volunteers welcome
- Sponsor
- Create Fertility Center
Aneuploidy
Aneuploidies and Different Stimulation Protocols
Our working hypothesis is that patients undergoing "in vitro" fertilization (IVF) with higher response to ovarian stimulation protocols recover a higher number of oocytes and, this elevated response could be translated into…
- Trial name
- NCT00802295
- Testing
- Gonadotrophins, Low dosis Gonadotrophin
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
No Condition
Comparison of Clinical Outcomes Between IVM and Minimal Stimulation IVF in Patients With PCOS
Polycystic ovarian syndrome (PCOS) is most common endocrinologic disease in women of reproductive age with incidence of 6.6 ~ 8%.
- Trial name
- NCT03134482
- Testing
- IVM, Minimal stimulation IVF
- Where
- 2 sites in South Korea
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- CHA University
Female Infertility, Ovarian Insufficiency
Efficacy Study Comparing the Effect of Clomiphencitrate to an Antagonist Protocol
The aim of this study is to assess the oocyte yield of infertile women with suspected or known poor ovarian reserve (POR) undergoing a GnRH antagonist protocol for IVF with Merional® starting either with a low (150 IU) or a high…
- Trial name
- CANTAPOR (NCT01577472)
- Testing
- High Dose Clomiphencitrat, Low Dose Clomiphencitrat
- Where
- Switzerland
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Infertility
Resveratrol as a Preventive Treatment of OHSS
Evaluation of resveratrol treatment oh ovarian hyperstimulation syndrome in egg donors
- Trial name
- RES-OHSS (NCT03446625)
- Testing
- Resveratrol
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Polycystic Ovary Syndrome
Response of VEGF and AT-II to HCG in PCOS
This research is to investigate the response of vascular active factors, vascular endothelial growth factor (VEGF) and angiotensin-Ⅱ (AT-Ⅱ) to ovary stimulation during 24h in patients with polycystic ovary syndrome…
- Trial name
- NCT02265861
- Testing
- HCG
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanjing University School of Medicine
Polycystic Ovary Syndrome, Ovarian Hyperstimulation Syndrome
In Vitro Maturation of Immature Oocytes
The aim of this study is to aspirate immature oocytes from antral follicles and mature the oocytes in vitro. These mature oocytes will serve for fertilization and the creation of embryos which will be replace in the uterus as…
- Trial name
- NCT00480337
- Testing
- In Vitro Maturation of immature oocytes
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Polycystic Ovarian Syndrome, Ovarian Hyperstimulation Syndrome
Ovarian Hyperstimulation Syndrome and Cabergoline
Cabergoline prevents ovarian hyperstimulation syndrome in high risk patients by disrupting follicular fluid hormone microenvironmentally altering the follicular fluid levels of insulin like growth hormone -I (IGF-I)…
- Trial name
- NCT01569256
- Testing
- Cabergoline
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanim Womens' Health and Teaching Hospital
Ovarian Hyperstimulation Syndrome
Cabergoline Reduces OHSS
The present study was designed to provide clinical confirmation of Cb2's value as a new approach in the prevention of increased vascular permeability and hemoconcentration, both signs of OHSS in humans, and in order to explore…
- Trial name
- NCT00440258
- Testing
- Cabergoline, MR, Ultrasound
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility, Breast Cancer
Effects of Controlled Ovarian Hyperstimulation (COH) With Letrozole and Gonadotropin
Fertility drugs have the effect of increasing hormone levels. Higher hormone levels from infertility treatments may increase breast cancer risk, but there has not been enough research to know for sure.
- Trial name
- NCT01403688
- Testing
- RPFNA
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Ovarian Stimulation
Human Menopausal Gonadotropin (HMG) vs Recombinant Follicle Stimulating Hormone (rFSH) in Gonadotropin Releasing Hormone (GnRH) Antagonist Cycles
A randomized controlled trial comparing the ongoing pregnancy rate (primary end-point) in 280 patients undergoing IVF/ICSI after stimulation with hp-hMG or rFSH controlled with a GnRH antagonist.
- Trial name
- NCT00669786
- Testing
- Human Menopausal Gonadotropin (HMG) & - Recombinant Follicle Stimulating Hormone (r-FSH)
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA