Clinical trials: Ovulation Disorder
Infertility
Does Clomiphene Citrate Used for Induction of Ovulation Effect Levels of AMH and Inhibin B
100mg clomiphene citrate used for ovulation induction. The investigators take blood sample at 3 and 10 days of menstruation and count AMH and inhibin B.
- Trial name
- NCT02036411
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Infertility, Induction of Ovulation
A Study to Evaluate the Tolerability, Safety and Pharmacokinetic Characteristics of DA-3803
This is a single-blind, randomized, comparative, phase I study to evaluate the tolerability, safety and pharmacokinetic characteristics of human chorionic gonadotropin between two recombinant hCG products named DA-3803 injection…
- Trial name
- NCT01851512
- Testing
- T-R (Test-Reference drug), R-T (Reference-Test drug)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Dong-A Pharmaceutical Co., Ltd.
Induction of Ovulation, PCO - Polycystic Ovaries
Sodium-Glucose Co-Transporter-2 Inhibitors as Adjuvant Therapy With Letrozole in Induction of Ovulation in Women With Polycystic Ovarian Syndrome
The aim of the study is to assess the efficacy of adjuvant therapy dapagliflozin, metformin as monotherapy and combination of both in comparison to control group in induction of ovulation with letrozole in women PCOS, focusing…
- Trial name
- SGLT-2/PCOS (NCT07589075)
- Testing
- Metformin 1000 mg Oral Tablet, Dapagliflozin 10 MG Oral Tablet [Farxiga], Combined Dapagliflozin-Metformin 5/1000mg
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Inositol, Testosterone
Evaluation of D-chiro-inositol Treatments
Healthy women will take tablets containing 600 mg D-chiro-inositol twice per day for one month. We will evaluate metabolic and hormonal.parameters, as insulienmia, glycemia, estradiol, testosterone.
- Conditions
- Inositol, Testosterone, Insulin, Ovulation
- Trial name
- NCT05448378
- Testing
- D-chiro-inositol
- Where
- 2 sites in Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lo.Li.Pharma s.r.l
Polycystic Ovary Syndrome
Letrozole Dose Increments in PCOS Patients Resistant to Letrozole
Objectives: To study the effect of Letrozole dose increments on ovulation rate and endometrial thickness as a primary outcomes in patients with polycystic ovary syndrome who previously resistant to letrazole conventional dose…
- Trial name
- NCT06403488
- Testing
- Letrozole 2.5mg
- Where
- 2 sites in Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Infertility
Comparison Between Recombinant Versus Urinary hCG for Ovulation Induction in High Responders
The purpose of this study is to compare the clinical outcomes of recombinant human chorionic gonadotrophin (rHCG) and urinary HCG (uHCG) in patients undergoing IVF cycles.
- Trial name
- NCT00415766
- Testing
- rHCG 250ug, uHCG 5000 IU, uHCG 7500 IU
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eugonia
Infertility, Decreased Ovarian Reserve
A Trial of Dehydroepiandrosterone (DHEA) Treatment for in Vitro Fertilization (IVF)
Our long term goal is to elucidate the role of DHEA on follicular dynamics in the human ovary and to better understand the interaction of DHEA supplementation with other treatments for ovulation induction, especially among older…
- Trial name
- NCT00419913
- Testing
- Dehydroepiandrosterone
- Where
- 2 sites in United States, Austria
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Subfertility
Does Hormonal Luteal Support After Intra-uterine Insemination (IUI) Increase the Pregnancy Rate?
A randomized study to investigate if hormonal luteal support after intra-uterine insemination (IUI) in ovulation induction cycles with human menopausal gonadotropin increases the pregnancy rate
- Trial name
- NCT00700492
- Testing
- progesterone
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Polycystic Ovary Syndrome, Ovulation Disorder
Clusterin Level and Polycystic Ovary Syndrome
Clusterin, a protein involved in metabolic syndrome, insulin resistance, and metabolic disorders associated with inflammation and oxidative stress such as atherosclerosis, Alzheimer's and some malignancies, has elevated levels in…
- Trial name
- NCT06601725
- Testing
- Clusterin level
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Anovulation, Polycystic Ovary Syndrome
Letrozole Versus Clomiphene Citrate for Ovulation Induction in Women With Poly Cystic Ovary Syndrome ( PCOS )
110 infertile women diagnosed as polycystic ovary syndrome (PCOS) at the age group of 20-35 distributed randomly : 55 women will receive letrozole 2.5mg twice daily orally from the 2nd day to the 6thday of the cycle for three…
- Trial name
- LVCCFOROI (NCT02551367)
- Testing
- Letrozole, Clomiphene citrate, hcg hormone
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- mostafa gomaa hamid halawa
Asymptomatic Diseases
Effect of Local Endometrial Injury on Pregnancy Outcomes During Ovulation Induction Cycles
The aim of this study is to detect whether or not performing an endometrial sampling in the cycle preceding ovulation induction with clomiphene citrate can improve pregnancy outcomes in the next cycle.
- Trial name
- NCT02345837
- Testing
- endometrial sampling, clomiphene citrate
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Al Hayat National Hospital
Polycystic Ovary Syndrome
Acupuncture for Polycystic Ovarian Syndrome
This is a randomized control trial of acupuncture for women with polycystic ovary syndrome. The study is triple-blinded.
- Trial name
- NCT00602940
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Polycystic Ovary Syndrome, Infertility
Letrozole vs Clomiphene Citrate for Induction of Ovulation in Women With Polycystic Ovarian Syndrome
It was randomised controlled study to compare the efficacy of clomiphene and letrozole in polycystic ovarian syndrome(PCOS) women with infertility.The aim was to select more appropriate treatment for ovulation induction in PCOS…
- Trial name
- NCT05702957
- Testing
- letrozole 2.5mg-7.5mg, Clomiphene Citrate 50mg-150mg
- Where
- Pakistan
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Menstrual Cycle, Ovulation
Apple Women's Health Study
This is an observational longitudinal study to advance the understanding of menstrual cycle and gynecologic health conditions including PCOS, infertility and breast cancer.The study will be hosted within the Research…
- Conditions
- Menstrual Cycle, Ovulation, Menstruation, Polycystic Ovary Syndrome
- Trial name
- NCT04196595
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
Ovulation, Menstruation
Impact of Menstrual Phase on Oral Glucose Sensitivity
In this study we are determining whether the hormones associated with the phases of the menstrual cycle (menstruation \& ovulation) influence taste sensitivity to glucose.
- Trial name
- NCT06800690
- Testing
- Urinary Estrogen Level
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Polycystic Ovary Syndrome
Effect of Ramadan Fasting on Ovulation and Insuline Resistance in Patients With PCOS
Polycystic ovary syndrome (PCOS) has a heterogeneous clinical presentation comprising reproductive (hyperandrogenism, menstrual irregularity, anovulation, infertility, pregnancy complications), metabolic [insulin resistance (IR)…
- Trial name
- NCT02499289
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Poor Response to Ovulation Induction, PCOS
The Angiotensin-Melatonin Axis in Poor and Hyper Responders for IVF Treatment
According the World Health Organization (WHO), infertility is a disease of the male or female reproductive system defined by the failure to achieve a pregnancy after 12 months or more of regular unprotected sexual intercourse.
- Conditions
- Poor Response to Ovulation Induction, PCOS, Endometriosis, Infertility, Female
- Trial name
- NCT05298657
- Where
- United Arab Emirates
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fatima College of Health Sciences
Ovulation Disorder
"Stair Step Study"
Rationale: There is some information suggesting that a progesterone-induced withdrawal bleeding before the start of ovulation induction in women suffering from oligo- or amenorrhea reduces pregnancy and live birth rate.
- Trial name
- NCT03309176
- Testing
- Medroxyprogesterone Acetate 10 MG, Stair step protocol without Medroxyprogesterone Acetate
- Where
- 3 sites in Netherlands
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Treatment Resistant Disorders
Adding L-carnitine in Clomiphene Resistant Polycystic Ovary Improves the Quality of Ovulation and the Pregnancy Outcome
Adding L-carnitine is more successful than clomiphene as a first line therapy for ovulation induction in women with clomiphene resistant PCOS
- Trial name
- NCT01665547
- Testing
- l-carnitine
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Infertility
Study of Axillary Skin Temperature as a Marker of Ovulation
Infertility is the most common reason women (aged 20-45yrs)see their GP, affecting 1 in 7 couples. Measuring basal body temperature is a technique that has been used since the 1930's to attempt to predict ovulation.
- Trial name
- NCT01360684
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Joanne Outtrim