Clinical trials: Oxygen Disorders
Acute Heart Failure, Pulmonary Congestion
Oxygen Targets in Acute Heart Failure With Pulmonary Congestion
REDOX-AHF compared two oxygen saturation targets in adults admitted with acute heart failure and clinical or radiological signs of congestion.
- Conditions
- Acute Heart Failure, Pulmonary Congestion, Hypoxemia
- Trial name
- REDOX-AHF (NCT05613218)
- Testing
- Oxygen
- Where
- 2 sites in Denmark
- Volunteers
- 135 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Asthma, Asthma (Diagnosis)
Intercostal and Thoracic Cage Stretching on Chest Expansion , Dyspnea ,Oxygen Saturation in Asthma
The rationale of this study is to clarify distinct role of these two stretching techniques in pulmonary rehabilitation. Insight gained from this research could provide evidence based recommendations for implementing these…
- Trial name
- NCT07331662
- Testing
- thoracic cage stretching, intercostal stretching
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Riphah International University
Physiological Responses, Pilates Exercise
Effect of Muscle Strengthening Training with Pilates Reformer on Overweight/obese and Normal Body Weight Women (PRET)
This study investigates the physiological responses and the metabolic burden of a Pilates Reformer strength training session in physically inactive premenopausal women with a body mass index of 18-24.9 and 25.01-39.9.
- Conditions
- Physiological Responses, Pilates Exercise, Overweight and Obese Women, Energy Expenditure
- Trial name
- PRET (NCT06675162)
- Testing
- Pilates Reformer Training
- Where
- 2 sites in Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Intracranial Meningioma, Neurologic Deficits
Hyperbaric Oxygen Therapy Can Improve Neurological State Post Meningioma Removal Surgery
The aim of the current study is to evaluate, in a prospective cross-over, randomized study, the effect of hyperbaric oxygen therapy (HBOT) on patients with chronic neurological deficits and cognitive impairment after anterior…
- Trial name
- NCT02084927
- Testing
- HBOT
- Where
- Israel
- Volunteers
- 62 people
- Sponsor
- Assaf-Harofeh Medical Center
Power, Metabolic Disturbance
Effect of 8-week Intake of 2S-hesperidin on Performance, Body Composition and Biochemicals Markers in Amateur Cyclists
This clinical study evaluates the effect of 500 mg of 2S-hesperidin for 8 weeks on performance (power generated in different metabolic zones), body composition (fat and muscle mass) and biochemical (antioxidant, inflammatory…
- Conditions
- Power, Metabolic Disturbance, Change, Body Weight, Changes Fatty
- Trial name
- HESPERFORMAN (NCT04597983)
- Testing
- 2S-hesperidin
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Francisco Javier Martínez Noguera
Chronic Respiratory Acidosis
Respiratory Stabilization in Chronic Acidosis Before Bronchofiberoscopy & Non-Invasive Ventilation Effectivenes
Bronchofiberoscopy (FOB) is a minimally invasive and safe procedure performed for diagnostic and therapeutic purposes. FOB frequently impairs respiratory function, which may lead to possible exacerbation of respiratory failure.
- Trial name
- NCT06970002
- Testing
- Use of NIV during FOB as a respiratory support method, Use of HFNC during FOB as a respiratory support method
- Volunteers
- 210 people
- Sponsor
- Medical University of Silesia
Covid19
Hyperbaric Oxygen for Long COVID-19 Pulmonary Sequela
This is a pilot study in 24 subjects where half will be randomized to 10 treatments with hyperbaric oxygen (HBO). It will primarily study pulmonary sequelae with imaging and physiological measurements (low dose chest computer…
- Trial name
- NCT04905888
- Testing
- Hyperbaric oxygen therapy
- Where
- United States
- Sponsor
- Peter Lindholm
COPD
Metabolism and Oxygen Consumption During Functional Electrical Stimulation Cycling in COPD
Chronic Obstructive Pulmonary Disease (COPD) had systemic repercussion and lead to peripheral muscular dysfunction. Muscular atrophy limits aerobic capacity and is a major limitation of daily activity and quality of life.
- Trial name
- NCT02594722
- Testing
- FES-cycling, Classic cycloergometer
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Rouen
Asthma
Effects of Balloon-blowing Exercises in 90/90 Bridge Position With a Ball on Pulmonary Function Among Asthmatic Patients
In asthma, the airways in the respiratory system can experience inflammation and constriction, causing increased difficulty in expelling air during exhalation.
- Trial name
- NCT06660537
- Testing
- Balloon-blowing exercises in 90/90 bridge position with a ball., Buteyko breathing exercises management
- Where
- Pakistan
- Volunteers
- 41 people
- Sponsor
- Foundation University Islamabad
Hypertonia
Grand Autohemo-Therapy With Oxygen-ozone on Patients With Hypertonia
The objective of this clinical study is to evaluate the influence of the Great autohemotherapy with oxygen-ozone (hyperbaric ozone therapy ) to describe the cardiovascular system in patients with resistant hypertension.
- Trial name
- HAB (NCT01902602)
- Where
- Germany
- Volunteers
- 19 people
- Sponsor
- Herrmann Apparatebau GmbH
Acute Ischemic Stroke
Hyperbaric Oxygen After Stroke Thrombectomy: A Multicenter Randomized Trial on Safety and Efficacy
1. The goal of this clinical trial is to evaluate the efficacy and safety of hyperbaric oxygen (HBO)in stroke patients after endovascular treatment 2.
- Trial name
- NOTICE-1 (NCT07049692)
- Testing
- Hyperbaric Oxygen Therapy, Conventional therapy group
- Where
- 2 sites in China
- Volunteers
- 424 people
- Sponsor
- Beijing Chao Yang Hospital
Breathing Exercise, Breathing Technique
Effectiveness of Balloon Blowing and Deep Breathing Exercise on Increasing Peripheral Oxygen Saturation in Patients With Chronic Obstructive Pulmonary Disease
This study aims to determine the effect of Balloon Blowing and Deep Breathing Exercise on Increasing Peripheral Oxygen Saturation in Patients with Chronic Obstructive Pulmonary Disease. The main question it aims to answer is: 1.
- Trial name
- NCT07646002
- Testing
- Balloon-blowing and Deep breathing exercises, Deep breathing exercises
- Where
- Indonesia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Primary Peritoneal Cavity Cancer, Stage I Endometrial Carcinoma
EF5 in Finding Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Cervical, Endometrial, or Ovarian Epithelial Cancer
This phase II trial is studying how well EF5 works in finding oxygen in tumor cells of patients who are undergoing surgery or biopsy for cervical, endometrial, or ovarian epithelial cancer.
- Conditions
- Primary Peritoneal Cavity Cancer, Stage I Endometrial Carcinoma, Stage I Ovarian Epithelial Cancer, Stage IA Cervical Cancer
- Trial name
- NCT00107445
- Testing
- EF5
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute (NCI)
Respiratory Failure With Hypoxia, Respiratory Failure Without Hypercapnia
Prone Positioning During High Flow Oxygen Therapy in Acute Hypoxemic Respiratory Failure
Background High-flow nasal cannula (NHF) are a promising tool for administering oxygen to critically ill patients with high respiratory demand.
- Trial name
- Optiprone (NCT03095300)
- Testing
- Prone position
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Catholic University of the Sacred Heart
Hypoxemic Acute Respiratory Failure
Closed Loop Oxygen Control in INtubated Critically Ill Patients
The deleterious effects of alveolar hyperoxia and (severe) hyperoxaemia are well described. Achieving safe and efficient oxygenation may be challenging.
- Trial name
- CLOC-IN (NCT06829732)
- Testing
- closed-loop oxygen control (CLOC), 2. manual oxygen titration (MOT)
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- Parc Taulí Hospital Universitari
Hypoxia, COPD
Intelligent Oxygen Therapy During Activities of Daily Living
The aim of this study is to assess whether an auto-titrating oxygen system can maintain constant oxygen saturations (SpO2) in patients who are on long-term oxygen therapy (LTOT) during activities of daily living.
- Conditions
- Hypoxia, COPD, Hyperoxia
- Trial name
- NCT02683486
- Testing
- Intelligent oxygen therapy (an auto-titrating oxygen system), Long-term oxygen therapy
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Imperial College London
CHD - Congenital Heart Disease, Single Ventricle Heart Disease
PRecision Integrated Saturation Monitor
The purpose of this study is to find out if an abdominal pulse oximeter device is as accurate as a conventional fingertip pulse oximeter in pediatric patients.
- Trial name
- PRISM (NCT07686341)
- Testing
- vital sign monitoring
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Le Bonheur Children's Hospital
Paediatric Asthma
Design, Development and Evaluation of a Digital Health Assistant for Paediatric Asthma
This study is to evaluate the efficacy of the digital health assistant (DHA) "Alex" in improving asthma control in asthmatic children and adolescents aged 10 to 19 compared to their baseline values.
- Trial name
- ALEX (NCT07472283)
- Testing
- Phase I (months 1-3): DHA core functionality, Phase II (months 3-6): platform augmentation, Embedded qualitative study
- Where
- 5 sites in Romania
- Volunteers
- 42 people
- Sponsor
- University Children's Hospital Basel
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 7 of 7)
NOTE: This is the seventh of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919137
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Bern
Surgical Complications From General Anesthesia, Hypertension
Monitoring Hypertensive Patients's Cerebral Oxygen Saturation
The purpose of this study is to determine whether there is a significant decrease in cerebral oxygen saturation in hypertensive patients undergoing major abdominal surgery and their correlation with standard monitoring parameters.
- Conditions
- Surgical Complications From General Anesthesia, Hypertension, Cerebral Ischemia, Cerebral Anoxia
- Trial name
- MHPCOS (NCT02147275)
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Huazhong University of Science and Technology