Clinical trials: Oxygenation Index
Acute Respiratory Distress Syndrome
Comparison of the PaO2/FiO2 Ratio to Other Oxygenation Indexes for the Classification of Severity of Acute Respiratory Distress Syndrome
In mechanically ventilated patients the PaO2/FiO2 ratio might not be the best reflection of the severity of ARDS. It does not incorporate variables and settings used during mechanical ventilatory support such as the positive end…
- Trial name
- NCT03946189
- Testing
- Obtaining arterial blood gases
- Where
- Lebanon
- Volunteers
- 150 people
- Sponsor
- American University of Beirut Medical Center
Positive End-expiratory Pressure (PEEP)
Electrical Impedance Tomography for Identification of Optimal Positive End-expiratory Pressure in Newborn Infants
Electrical impedance tomography (EIT) enables assessment of regional lung ventilation at the bedside. EIT has been safely used in newborn infants to image intrathoracic lung volume patterns as early as from the first minute of…
- Trial name
- NCT05612256
- Testing
- Electrical impedance tomography (EIT), Forced oscillation technique (FOT), Saturation oxygenation pressure index (SOPI)
- Where
- Switzerland
- Volunteers
- 86 people
- Sponsor
- University Children's Hospital Basel
Hemodynamic Monitoring
Starling Registry Study
Hemodynamic optimization of critically ill patients is a goal for clinicians in order to afford the patient the best possible outcomes.
- Trial name
- NCT04648293
- Testing
- Starling
- Where
- 9 sites in United States
- Volunteers
- 1,207 people
- Sponsor
- Baxter Healthcare Corporation
Body Weight, Obesity
The Optimum Time for Preoxygenation Based on Body Mass Index
The purpose of this study is to evaluate the relationship between the time needed to raise the oxygen concentration in patient's blood to 90% and his/or her body mass index.
- Trial name
- NCT01114932
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Cedars-Sinai Medical Center
Hypoxemic Respiratory Failure, Oxygen Toxicity
Handling Oxygenation Targets in COVID-19
Patients with COVID-19 and hypoxaemic respiratory failure and admitted to the intensive care unit (ICU) are treated with supplementary oxygen as a standard. However, quality of quantity evidence regarding this practise is low.
- Trial name
- HOT-COVID (NCT04425031)
- Testing
- Low oxygenation target, High oxygenation target
- Where
- 10 sites in Denmark, Norway and 1 more
- Volunteers
- 726 people
- Sponsor
- Aalborg University Hospital
Acute Respiratory Distress Syndrome, Pneumonia
The Relationship Between Driving Pressure, Mechanical Power, Oxygenation and Saturation Indices: Retrospective Observational Study
By using Mechanical Power and Driving Pressure instead of Pmean we calculate new oxygen saturation indices like Driving Pressure Oxygen Index (OIDP), Dynamic Power Oxygen Index (OIMPdyn), Total Power Oxygen Index (OIMPtot)…
- Trial name
- NCT05677165
- Where
- Turkey (Türkiye)
- Volunteers
- 361 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Infant, Premature, Stress, Psychological
Personalized Music Therapy for Preterm Infants
Preterm infants in the Neonatal Intensive Care Unit (NICU) face environmental and clinical stressors that may affect physiological stability and development.
- Trial name
- NCT07295106
- Testing
- Personalized Music Therapy (PMT), Quiet Rest
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fabrizio Faina
Major Gynecological Cancer Surgery, Low Flow Anesthesia
The Relationship Between Body Mass Index and Patient Outcomes in Low Flow Anaesthesia
This study was designed as a prospective observational study.
- Trial name
- NCT06636448
- Testing
- the effect of body mass index during low-flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Oxygenation Index
The Optimal Intraoperative Supplemental Oxygen Administration During Minimally Invasive Esophagectomy
The study hypothesized that a relative low oxygen concentration (40%) supplemental would be advantageous to protect the pulmonary function of patients, comparied with conventional high oxygen concentration (80%).
- Trial name
- NCT02026739
- Testing
- low supplemental oxygen concentration, high supplemental oxygen concentration (conventional)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tan, Lijie
ARDS
Effectiveness of Recruitment Maneuvers and Lung Protective Ventilation Strategy in ARDS
The study was designed to comparison the effectiveness of recruitment maneuvers(RM) and lung protective ventilation strategy(LPVS) for patients with moderate to severe ARDS.
- Trial name
- ARDS (NCT05023226)
- Testing
- RM, LPVS
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Asia University
Laparoscopic Hysterectomy
Effect of Trendelenburg Position on Patient State Index
The goal of this observational study is to evaluate whether the Trendelenburg position affects electroencephalography-based depth of anesthesia monitoring and cerebral oxygenation during general anesthesia.
- Trial name
- NCT07467200
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Oxygen Reserve Index Values
Evaluation of Oxygen Reserve Index According to Glasgow Coma Scale in Providing Oxygenation in Intracranial Surgery
Evaluation of oxygen reserve index according to Glasgow Coma Scale in providing oxygenation in intracranial surgery
- Trial name
- NCT05953493
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Trakya University
Regional Anesthesia, Interscalene Blocks
Comparative Impacts of Two Anesthesia Methods on Peripheral Tissue Oxygenation in the Upper Limb
This study will aim to compare the effects of two different anesthesia techniques-general anesthesia (GA) and interscalene brachial plexus block (ISB)-on forearm tissue oxygenation in patients undergoing shoulder surgery.
- Conditions
- Regional Anesthesia, Interscalene Blocks, Shoulder Surgery, Perfusion Index
- Trial name
- NCT07449611
- Testing
- General Aneasthesia, Interscalene block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Sakarya University
One-lung Ventilation (OLV)
Correlation of Oxygenation and Saturation Indices in One-Lung Ventilation
One-lung ventilation is commonly used during thoracic surgery but is frequently associated with impaired oxygenation and altered respiratory mechanics.
- Trial name
- OLV-INDICES (NCT07381517)
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Laparoscopic Surgery, Pneumoperitoneum
Role of Individualized PEEP Vs Fixed PEEP in Mechanical Ventilation During Laparoscopic Surgeries
To compare the effects of Individualized positive end-expiratory pressure with recruitment maneuver on respiratory parameters and oxygenation in mechanical ventilation during laparoscopic surgeries with the fixed positive…
- Conditions
- Laparoscopic Surgery, Pneumoperitoneum, Positive End Expiratory Pressure (PEEP)
- Trial name
- NCT06929078
- Testing
- Protective lung ventilation methods with different positive end-expiratory pressure during Laparoscopic Surgeries
- Where
- Pakistan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Noor-Ul-Ain
Out of Hospital Cardiac Arrest, Extracorporeal Cardiopulmonary Resuscitation
The CPR, Pre-hospital ECPR and Early Reperfusion Study: A Target Trial Emulation
CHEER4TTE is a target trial emulation, designed to simulate a randomised controlled trial by utilising data from pre-existing data sources.
- Trial name
- CHEER4TTE (NCT07679737)
- Testing
- Extracorporeal cardiopulmonary resuscitation
- Where
- Australia
- Volunteers
- 250 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Anesthesia; Functional
Evaluation of Oxygenation Parameters in Patients Undergoing Rhinoplasty Under General Anesthesia
The investigators are planning to compare the oxygenation values (Pao2/fio2, lactate etc.) in patients who underwent TCI and inhalation anesthesia in rhinoplasty operation.
- Trial name
- NCT05754515
- Testing
- target controlled infusion (TCI) group
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Duzce University
Acute Hypoxemic Respiratory Failure
A Novel Index to Predict the Failure of High-flow Nasal Cannula in Patients with Acute Hypoxemic Respiratory Failure
High-flow nasal cannula (HFNC) is increasingly used in patients with acute hypoxemic respiratory failure (AHRF) and has been shown to improve outcome in specific patient categories, including community acquired pneumonia and…
- Trial name
- NCT05549882
- Testing
- no intervention
- Where
- China
- Volunteers
- 504 people
- Sponsor
- Southeast University, China
Atelectasis
Effects of Different Inhalation Oxygen Concentrations on Postoperative Atelectasis
This study was a single-center, prospective, randomized controlled, two-arm study. This study will be conducted in the First Hospital of China Medical University.
- Trial name
- DIOCA (NCT05627024)
- Testing
- 30% Oxygen, 60% Oxygen
- Where
- China
- Volunteers
- 96 people
- Sponsor
- China Medical University, China
Pediatric Acute Respiratory Distress Syndrome
Comparison of Oxygenation Index and Oxygen Stretch Index
Pediatric acute respiratory distress syndrome (pARDS) is a heterogeneous clinical syndrome that causes high rates of mortality and morbidity.
- Trial name
- NCT06586411
- Where
- 7 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Dr. Behcet Uz Children's Hospital