Clinical trials: PVI
Peripheral Vascular Diseases, Kidney Diseases
A Contrast Medium Sparing Strategy Using Automated CO2 Injection During PVI for Prevention of Major Adverse Kidney Events (MAKE)
The primary objective of the trial is to evaluate if an iodinated contrast medium sparing strategy using automated Carbon Dioxide (CO2) Injection prevents Major Adverse Kidney Events up to 90 days (MAKE90) in patients at…
- Trial name
- PeriPREVENT (NCT06656988)
- Testing
- CO2, Iodinated Contrast Media (ICM)
- Where
- 11 sites in Austria, Germany
- Volunteers
- 1,960 people
- Sponsor
- University of Leipzig
Atrial Fibrillation, Atrial Fibrillation Recurrent
DIGITal mOnitoring afTer Af abLation
Recurrence of atrial fibrillation (AF) after a pulmonary vein isolation (PVI) procedure is frequent. Current follow up with Holter monitoring and electrocardiograms (ECG) during outpatient clinic consultations cover only short…
- Conditions
- Atrial Fibrillation, Atrial Fibrillation Recurrent, PVI
- Trial name
- DIGITOTAL (NCT05486364)
- Testing
- Digital Monitoring, Standard of care
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Ziekenhuis Oost-Limburg
Intraoperative Hypotension, Intraoperative Complications
Comparison of Conventional Fluid Management Protocol With Targeted Pleth Variability Index (PVI) Monitoring Protocol During Total Abdominal Hysterectomy and Bilateral Salpingooferectomy Operation
This study aims to compare the volume management methods performed by using conventional method and PVI monitoring in intraoperative fluid treatment during bilateral salpingo-oophorectomy and total hysterectomy operation.
- Conditions
- Intraoperative Hypotension, Intraoperative Complications, Hypervolemia, Acute Renal Failure
- Trial name
- NCT04775576
- Testing
- Pleth Variability Index, Conventional fluid theraphy, Anesthesia method
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Surgery
Continuous Non-Invasive SpHb and PVI Monitoring on Intra-Operative and Post-Surgical Clinical Outcomes
The study evaluates the use of noninvasive hemoglobin with In Vivo feature and PVi monitoring using pulse-oximetry based technologies and their effect on the management of transfusion and infusion decisions and clinical outcomes…
- Trial name
- NCT02986789
- Testing
- In vivo SpHb and PVi Monitoring
- Volunteers
- 43 people
- Sponsor
- Masimo Corporation
Atrial Fibrillation, Arterial Hypertension
Comparison of Redo PVI With vs. Without Renal Denervation for Recurrent AF After Initial PVI
The objective of this study is to compare the elimination of atrial fibrillation in patients with recurrent atrial fibrillation despite prior pulmonary vein isolation (PVI) when undergoing repeat PVI (control) vs repeat PVI plus…
- Trial name
- NCT01959997
- Testing
- Redo PVI, PVI + RDN
- Where
- 2 sites in United States, Russia
- Volunteers
- 60 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Perfusion Index and Pleth Variability Index, Interscalene Blocks
Perfusion Index (PI) and Pleth Variability Index (PVI) in Patients With Interscalene Blocks in Orthopedic Surgery
The purpose of this study is to: 1. To describe effects of interscalene nerve blocks on perfusion index (PI) and pleth variability index (PVI) (Radical 7, Masimo Cooperation, Irvine, CA) before and after induction of general…
- Conditions
- Perfusion Index and Pleth Variability Index, Interscalene Blocks, Orthopedic Surgery
- Trial name
- PI-PVI (NCT01389011)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Johannes Gutenberg University Mainz
Paroxysmal Atrial Fibrillation
Evaluation of QDOT MICRO™ Catheter for Pulmonary Vein Isolation in Subjects With Paroxysmal Atrial Fibrillation
Prospective, non-randomized, pre-market clinical evaluation of the QDOT MICRO™ Catheter to demonstrate the safety and effectiveness when compared to an historical control performance goal.
- Trial name
- Q-FFICIENCY (NCT03775512)
- Testing
- RF Ablation with QDOT Micro
- Where
- 22 sites in United States
- Volunteers
- 283 people
- Sponsor
- Biosense Webster, Inc.
Atrial Fibrillation, Atrial Fibrillation (Paroxysmal)
Wide-Antral Pulmonary Vein Isolation in Atrial Fibrillation Ablation with a Single-shot Technique (WIDER-PVI)
The WIDER PVI study is a multicentre randomized clinical trial to compare the efficacy of antral versus extended antral PVI in patients with paroxysmal or persistent AF undergoing this procedure using a cryoablation balloon…
- Trial name
- WIDER-PVI (NCT06698159)
- Testing
- Cryoablation with cryoballoon 28 mm, Cryoablation with cryoballoon 31 mm
- Where
- 17 sites in Italy, Spain
- Volunteers
- 440 people
- Sponsor
- Hospital Universitario 12 de Octubre
Paroxysmal Atrial Fibrillation
Cryoballoon PVI With PWI Versus PVI Alone In Patients With PAF
Cryoballoon ablation has emerged as a safe and effective strategy for treatment of atrial fibrillation (AF) for which it has recently received a 'first-line' therapy indication by the FDA.
- Trial name
- NCT05296824
- Testing
- Cryoballoon ablation for the treatment of atrial fibrillation
- Where
- 4 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Sacramento EP Research
Ventilation Mode, Pleth Variability Index
Effects of Volume and Pressure-Controlled Ventilation on Cerebral SpO2, PI, and PVI Index in Septoplasty
Objective: This study was designed to evaluate the accuracy of Pleth Variability Index (PVI), Perfusion Index (PI) and Regional Oxygen Saturation (rSO2) in both ventilation modes in patients undergoing septorhinoplasty operation…
- Conditions
- Ventilation Mode, Pleth Variability Index, Perfusion Index, Regional Cerebral Oxygen Saturation
- Trial name
- NCT06407362
- Testing
- Cerebral Oxygen Saturation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Paroxysmal Atrial Fibrillation
ADVENT Post Approval Study
The ADVENT Post Approval Study (PAS) is a prospective, global, multicenter, observational study.
- Trial name
- ADVENTPAS (NCT06431815)
- Testing
- FARAPULSE™ Pulsed Field Ablation System
- Where
- 30 sites in United States, Brazil and 2 more
- Volunteers
- 228 people
- Sponsor
- Boston Scientific Corporation
Shock, Septic Shock
Reliability of PVI Changes During Tidal Volume Challenge in ICU Patients
The aim of this study is to assess whether changes in the plethysmography variability index, during a tidal volume challenge, can reliably detect simultaneous changes in arterial blood pressure pulsatility, in patients…
- Conditions
- Shock, Septic Shock, Sepsis, Hemodynamic Instability
- Trial name
- NCT05428423
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Bicetre Hospital
Effects of Anesthesia Spinal and Epidural in Pregnancy
The Relationship Between Perfusion Index and Pleth Variability Index and Hemodynamics in Spinal Anesthesia
In routine practice, the preferred anesthesia method in cesarean section operations is spinal anesthesia, but it causes hypotension in a significant part of the patients.
- Trial name
- NCT05174260
- Testing
- perfusion index, pleth variable index
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- Adiyaman University
Fluid Overload Without Edema
Fluid Administered According to PVI Versus Fluid Management in Laparoscopic Trendelenburg Surgeries
Investigating the ideal fluid management in Trendelenburg positions during lower abdominal laparoscopic surgeries in gynecological oncology and surgical oncology patients
- Trial name
- NCT06633510
- Testing
- massimo group, standart group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Surgeries Undergoing General Anesthesia
PPV vs PVI in the Supine and Prone Position
This is a prospective study that will record the Pulse Pressure Variability (PPV) from the arterial line and Plethysmography Variability Index (PVI) from the pulse oximeter while the patient is in the supine position and then…
- Trial name
- NCT07415603
- Testing
- Observation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Joseph D. Tobias
Paroxysmal Atrial Fibrillation
Evaluation of Ablation Index and VISITAG™ (ABI-173)
The purpose of this study is to assess the safety, acute and long term effectiveness, during standard RF ablation procedures while using Ablation Index and VISITAG™ software in combination with a Thermocool SmartTouch® (ST) or…
- Trial name
- VISTAX (NCT03062046)
- Testing
- RF ablation
- Where
- 17 sites in Austria, Belgium and 7 more
- Volunteers
- 340 people
- Sponsor
- Biosense Webster, Inc.
Atrial Fibrillation (AF), Esophageal Perforation
Esophageal Safety of High and Very High Power Short Duration Pulmonary Vein Isolation: a Randomized Comparison of the 50W and 90W Power Settings
Pulmonary vein isolation (PVI) is the most effective means of maintaining sinus rhythm in atrial fibrillation (AF), while a widely used approach to PVI is point-by-point radiofrequency (RF) catheter ablation.
- Conditions
- Atrial Fibrillation (AF), Esophageal Perforation, Esophageal Perforation, Traumatic
- Trial name
- HPSD-Esophagus (NCT06617442)
- Testing
- Pulmonary vein isolation
- Where
- Hungary
- Volunteers
- 150 people
- Sponsor
- Semmelweis University
Atrial Fibrillation, Atrial Arrhythmia
Studying Heart Ablation After Left Atrial Closure in High-Bleeding-Risk Atrial Fibrillation Patients
The purpose of this multicenter study is to collect information from routine clinical practices for patients with left atrial appendage occlusion (LAAO) devices presenting for pulmonary vein isolation (PVI) or left atrial…
- Trial name
- PROCEED-AF (NCT07580937)
- Testing
- Data collection
- Where
- 20 sites in United States, Belgium and 7 more
- Volunteers
- 198 people
- Sponsor
- University of Chicago
Gynecological Surgery
Plethysmography Variability Index as an Indicator of Adequacy of Preload
The investigators propose a prospective observational trial. The investigators plan to enroll 40 female subjects scheduled for elective robotic gynecological surgery under general anesthesia.
- Trial name
- NCT01285622
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- University of Louisville
AF - Atrial Fibrillation, HTN-Hypertension
Pulmonary Vein Isolation (PVI) Combined With Renal Denervation (RDN) in Atrial Fibrillation (AF) and Hypertension (HTN)
The close relationship between the increase of sympathetic tension, AF, and HTN cannot be ignored. In addition, the significant failure rate of PVI (20-50%) in the treatment of AF makes it very necessary to explore the effect of…
- Trial name
- NCT05841615
- Testing
- Renal Denervation operation, Pulmonary vein isolation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital of Xiamen University