Clinical trials: Pachychoroid Disease
Pachychoroid Disease
Progression Patterns of Choroidal Venous Alterations
This study is about understanding how a condition called pachychoroid changes over time. Pachychoroid refers to an anatomic choroidal characteristic with abnormally thick choroid or abnormally dilated Haller's vessels.
- Trial name
- CVA (NCT07236671)
- Where
- 4 sites in Hong Kong, Malaysia and 1 more
- Volunteers
- 250 people
- Sponsor
- Singapore National Eye Centre
Pachychoroid Disease
Analysis of the Pachychoroid Phenotype in an Asian Population
The understanding of pachychoroid phenotype is incomplete. It is important to understand the risk of conversion from an uncomplicated pachychoroid phenotype to the pachychoroid disease phenotype, to guide appropriate management…
- Trial name
- NCT04498000
- Where
- 2 sites in Singapore
- Volunteers
- 112 people
- Sponsor
- Singapore National Eye Centre
Ocular Rosacea, Pachychoroid Disease
Research Into Diagnostic and Prognostic Molecular and Imaging Biomarkers of Ocular Disorders Associated With Neurovascular Deregulation: Biocor Cohort
BIOCOR is an interventional clinical trial whose main objectives are Objectif are identify molecular biomarker(s) of ocular rosacea and pachychoroid.
- Trial name
- BIOCOR (NCT06466018)
- Testing
- Schirmer test paper
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Clinact
Central Serous Chorioretinopathy
Central Serous Chorioretinopathy Registry and Pachychoroid Observation and Natural History Study
Objectives: 1. To conduct a Natural History Observation Study to characterize the clinical features and progression of Central Serous Chorioretinopathy (CSCR) from the earliest to the vision-threatening stages. 2.
- Trial name
- CSCR POOH (NCT05278169)
- Where
- 3 sites in Hong Kong
- Volunteers
- 350 people
- Sponsor
- Chinese University of Hong Kong
Glaucoma, Retinal Vascular Disorder
Study of Human Ocular Hemodynamics by Holography Dopple
Prospective, interventional, non-randomized, open-label study, multi-center, Gehan-designed study with sequential inclusions in each subgroup, ranging from 4 subjects to a maximum 37 subjects per subgroup included
- Trial name
- HoLoEye (NCT06989996)
- Testing
- Images Acquisition
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Pachychoroid Disease
Choroidal Venous Congestion Following Scleral Buckling - An Imaging Study
This study aims to understand how blood flow at the back of the eye changes over time after this surgery. By studying these changes, the investigators hope to gain insights that could help improve the understanding of other eye…
- Trial name
- SB (NCT07260097)
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore National Eye Centre
Choroidal Neovascularization, Choroid Disease
Treatment of Polypoidal Choroidal Vasculopathy in Pachychoroid
This study will evaluate patients with diagnosis of polypoidal choroidal vasculopathy (PCV) in pachychoroid treated with combined therapy, consisting in photodynamic therapy (PDT) and 3 intravitreal therapy (IVT) of Aflibercept…
- Trial name
- NCT04075188
- Testing
- Aflibercept Injection
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo
Age - Related Macular Degeneration (AMD), Diabetic Macular Edema
Wide Field OCTA in Ocular Diseases
The main retinal diseases, whether or not associated with specific mutations genetic, cause progressive degeneration of vascular retinal structures and not vascular, resulting in decreased visual function.
- Conditions
- Age - Related Macular Degeneration (AMD), Diabetic Macular Edema, Diabetic Retinopathy, Myopia
- Trial name
- WOOD-2025 (NCT07298174)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Age-Related Macular Degeneration, Pachychoroid Neovasculopathy
Prospective triAl of Modified Treat-and-extend Regimens With BroLucizumab in pachychOroid Neovasculopathy
PNV is a recently described clinical entity; therefore, studies about treatment efficacy and safety are few, with limited follow-up and a small number of participants.
- Trial name
- PABLO (NCT05672979)
- Testing
- Brolucizumab Injection [Beovu]
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Yeungnam University College of Medicine