Clinical trials: Pain, Chronic Post-Surgical
Pain, Chronic Post-Surgical
PERIoperative Holistic RIsk Factor SCreening in the Prevention of Persistent Pain
Assessment and management for improved wellbeing after elective surgery (PERISCOP³E-Care) Diagnostic assessment tool evaluation and cut-off determination for participation in a transmural perioperative care program
- Trial name
- PERISCOPEcare (NCT05526976)
- Testing
- PERISCOPE-care
- Where
- 2 sites in Belgium
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Chronic Post-Surgical Pain
Pre-op Cognitive Behavior Therapy to Decrease Chronic Post-Surgical Pain in TKA
A significant number of patients develop chronic post-surgical pain (CPSP) following knee replacement surgery. Proposed is the testing of a novel computer-assisted behavioral intervention integrating motivational interviewing in…
- Trial name
- NCT04814992
- Testing
- Computer-Assisted Preoperative CBT Intervention (PAINTrainer)
- Where
- 4 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Chronic Postoperative Pain, Chest Pain
The Effectiveness of Thoracal Epidural Steroid and Local Anesthetic Injection
The primary objective was to evaluate the effectiveness of thoracic interlaminar epidural injections in alleviating pain and enhancing function in patients suffering from chronic mid and/or upper back pain.
- Conditions
- Chronic Postoperative Pain, Chest Pain, Back Pain
- Trial name
- NCT06507995
- Testing
- thoracic interlaminar epidural injection
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara University
Chronic Pain
Sensory Abnormalities in Post-surgical Peripheral Neuropathy
The concept of normality is a cornerstone in medical practice and research. As an example, in clinical chemistry, a laboratory value based on a plasma sample exceeding the +/- 1.96 x standard deviation (SD) range, referenced from…
- Trial name
- NCT03966677
- Where
- Denmark
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Acute Postoperative Pain, Chronic Postoperative Pain
Menstrual Phase and Postoperative Pain
Fluctuations of female sex hormones during the menstrual cycle influence pain perception. Endogenous pain is pronounced in the follicular phase of the menstrual cycle.
- Trial name
- NCT02137135
- Testing
- HAD scale, The SF 12 test, Visual analogue score
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Chronic Postoperative Pain
Preoperative Erector Spinae Plane Block Versus Paravertebral Plane Block in Decreasing Post Mastectomy Pain Syndrome
Breast cancer is considered the commonest malignancy affecting women with an incidence exceeding one million cases per year. Although it has a favorable prognosis with improved lines of treatment, some complications may still…
- Trial name
- NCT06036979
- Testing
- Paravertebral plane block, Erector spinae plane block, Intravenous morphine, ketorlac and paracetamol
- Where
- Egypt
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Inguinal Hernia, Chronic Pain
Trigger-point Blockade in Persistent Pain After Open Groin Hernia Repair
Groin hernia repair is a common procedure performed in approximately 2,000 patients per one million inhabitants. Severe chronic pain following groin hernia repair is seen in 2-5% of the patients indicating that a large number of…
- Trial name
- Trigger-open (NCT02065219)
- Testing
- Bupivacaine
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Pain Syndrome
Pain After Removal of Mandibular Third Molars With or Without Advanced Platelet-rich Fibrin
Pain is the most common complication following surgical removal of an impacted mandibular third molar. Several risk factors may increase the intensity and duration of pain following removal of mandibular third molars.
- Trial name
- NCT06377839
- Testing
- Advanced platelet-rich fibrin in the ekstraction socket
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Chronic Pain, Pain Measurement
Relationship of Intra-Epidermal Nerve Fibre Density (IENFD) and Structure to Chronic Post-Mastectomy Pain Syndrome (PMPS)
This is a retrospective, observational study which will utilise the Edinburgh Cancer Research Centre's Tissue Bank to provide samples for IENFD testing in those who have undergone mastectomy surgery for breast cancer.
- Conditions
- Chronic Pain, Pain Measurement, Mastectomy, Postoperative Pain
- Trial name
- NCT02919891
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Royal Infirmary of Edinburgh
Pain, Post Operative Pain
Patient Reported Outcomes, Postoperative Pain and Pain Relief After Day Case Surgery (POPPY)
Around 3 out of 4 operations in the UK are performed as day-case, meaning the patient goes home on the same day of their operation.
- Conditions
- Pain, Post Operative Pain, Opioid Use, Chronic Pain
- Trial name
- POPPY (NCT06008496)
- Testing
- Day case surgery
- Where
- United Kingdom
- Volunteers
- 7,839 people, healthy volunteers welcome
- Sponsor
- University Hospital Plymouth NHS Trust
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Acute Post-operative Pain, Chronic Post Operative Pain
Duloxetine Impact on Postoperative Pain Control and Outcomes
1. Evaluate differences between patients taking Duloxetine or placebo following lateral lumbar interbody fusion for postoperative narcotic consumption. 2.
- Conditions
- Acute Post-operative Pain, Chronic Post Operative Pain, Narcotic Use, Opioid Use
- Trial name
- NCT05611749
- Testing
- Duloxetine 60 MG
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Scripps Health
Pain Threshold
Chronic Pain After Operation for Breast Cancer
The purpose of this study is to identify intraindividual as well as iatrogenic factors disposing for the development of chronic and acute pains after surgery for breast cancer in order to improve treatment and prevent the…
- Trial name
- NCT00739544
- Testing
- 1
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Gynecologic Cancers, Postoperative Pain
Postoperative Chronic Pain in Gynaecological Cancer Surgery
The aim of this study was to determine the incidence of postoperative chronic pain in gynaecological cancer surgery and the analgesia methods used for postoperative analgesia.
- Trial name
- NCT07077889
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Duygu Akyol
Acute Postoperative Pain, Chronic Postoperative Pain
Femoral and Epidural Block After Total Knee Arthroplasty
Total knee prosthetic replacement causes severe postoperative pain. Various analgesic techniques have been used in pain control.
- Trial name
- NCT02115945
- Testing
- DN4 test, The SF 12 test, HAD scale
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Chronic Periodontitis
To Compare Efficacy of Low Dose Diclofenac (25mg) in Management of Postoperative Pain After Periodontal Flap Surgery
Pain after periodontal surgical procedures is a common manifestation. The perception of pain is highly subjective and varies substantially among individuals.
- Trial name
- NCT03519152
- Testing
- low dose diclofenac
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Heart Surgery
The Effect Of Multimodal Analgesia On Chronic Pain
This study aimed to show the characteristics and predictors of chronic pain after a mini-thoracotomy. Non-Coronary Heart Surgery patients were scheduled for the study.
- Trial name
- NCT02660749
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tobb University of Economics and Technology
Osteoarthritis, Pain
fMRI and Central Sensitization in Chronic Knee Osteoarthritis. A Pre and Post TKR Study
Painful osteoarthritis (OA) is the 4th largest cause of disability in the UK. Preoperative temporal summation, a measure of central pain facilitation, has been shown to predict postoperative pain after total knee replacement…
- Conditions
- Osteoarthritis, Pain, Postoperative Pain, Surgery
- Trial name
- NCT03126279
- Testing
- Total Knee Replacement Surgery
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Peripheral Nerve Injuries
Chronic Neuropathic Pain After Nerve Repair Hand Surgery
This study intends to compare the patients with pain with those who underwent same procedure without developing pain. The patients with pain and without pain will be further analyzed in respect to clinical differences, biomarkers…
- Trial name
- NCT03174665
- Testing
- No intervention
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Chronic Pain, Postoperative, Quality of Life
Quality of Life and Pain After Appendectomy in Children
Acute appendicitis is one of the most common emergency general surgical conditions worldwide and represents the leading cause of emergency abdominal surgery in children.
- Conditions
- Chronic Pain, Postoperative, Quality of Life, Functional Ability, Appendectomy
- Trial name
- CAPA-Peds (NCT07629362)
- Where
- Turkey (Türkiye)
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital