Clinical trials: Pain, Post Surgical
Obesity, Postoperative Pain
Pregabalin in the Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy (LSG).
The aim of this clinical trial is to assess preemptive oral pregabalin administration in the obese patients undergoing laparoscopic sleeve gastrectomy.
- Conditions
- Obesity, Postoperative Pain, Postoperative Nausea and Vomiting, Opioid Use
- Trial name
- NCT05804591
- Testing
- Pregabalin 150mg
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Medical University of Warsaw
Serratus Plane Block, Postoperative Hyperalgesia
Effect of Liposome Bupivacaine Serratus Plane Block on Postoperative Hyperalgesia and Chronic Post-surgical Pain in Patients Undergoing Radical Mastectomy
Radical mastectomy is currently the mainstream surgical treatment for breast cancer. Patients often experience significant postoperative pain, and some may develop chronic pain.
- Conditions
- Serratus Plane Block, Postoperative Hyperalgesia, Chronic Post-surgical Pain, Liposomal Bupivacaine
- Trial name
- NCT07289178
- Testing
- Serratus Plane block (single injection)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Irreversible Pulpitis
Effect of Conservative Root Canal Instrumentation on the Release of Inflammatory Mediators in Root Canal Treatments
The goal of this clinical trial is to evaluate the expression of inflammatory mediators in the crevicular fluid and periodontal ligament after one-visit root canal treatment of mandibular molars of patients with asymptomatic…
- Trial name
- NCT06237985
- Testing
- ProTaper Gold file system, OneShape file system, TruNatomy file system
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Opioid Use, Auriculotherapy
Auriculo-Nerve Stimulation on Post-Operative Opioid Requirement
The NSS-2 BRIDGE® device (NSS stands for Neuro-Stimulation System) is a disposable device that stimulates the branches of cranial nerves and of the superficial cervical plexus innervating the ear.
- Conditions
- Opioid Use, Auriculotherapy, Pain, Abdominal, Cancer Pain
- Trial name
- NCT05506878
- Testing
- NSS-2 BRIDGE
- Where
- 4 sites in United States
- Volunteers
- 286 people
- Sponsor
- Jacques E. Chelly
Postoperative Pain, Acute
Ketorolac Intravenous Regional Analgesia in Lower Limb Surgeries
Tourniquet, a compressing device, otherwise its use in intravenous regional anesthesia, is commonly used in particular orthopedic surgeries.
- Trial name
- K-IVRAg (NCT05543785)
- Testing
- Ketorolac, Control
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Mansoura University
Surgical Complication, Pain, Postoperative
Anti-inflammatory Effect of Platelet-Rıch Fıbrın
This study evaluated the anti-inflammatory effect of platelet-rich fibrin (PRF) applied to the extraction socket after impacted mandibular third molar surgery with subjective and objective parameters.
- Conditions
- Surgical Complication, Pain, Postoperative, Edema Face
- Trial name
- NCT05336578
- Testing
- Platelet rich fibrin application
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Nilay Er
Postoperative Pain
Nalbuphine as an Adjuvant to Intravenous Regional Anesthesia
The effect of addition of nalbuphine to lidocaine in intravenous regional anesthesia
- Trial name
- NCT02678585
- Testing
- Nalbuphine, Lidocaine
- Where
- Egypt
- Volunteers
- 106 people
- Sponsor
- Assiut University
Analgesia, Pain, Postoperative
Postoperative Analgesic Effects of Bilateral External Oblique Intercostal Block in Laparoscopic Cholecystectomy Surgery
The aim of our study is to reduce postoperative pain by performing external oblique intercostal block in L/S cholecystectomy surgeries. Our main goal is to provide well managed post-operative analgesia.
- Trial name
- NCT05444985
- Testing
- Pain Management
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Samsun University
Laparoscopic Gastric Bypass, Obesity
Ketamine vs Hydromorphone
This study will help to determine if investigators can minimize narcotic use in laparoscopic gastric bypass patients while maintaining adequate pain control.
- Conditions
- Laparoscopic Gastric Bypass, Obesity, Pain, Postoperative
- Trial name
- NCT03001843
- Testing
- Ketamine, Narcotics, pain scale
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Florida
Postoperative Pain Management
mTLIP vs QIPB for Postoperative Analgesia in Lumbar Microdiscectomy Surgery
The aim of this prospective randomized clinical study is to compare the analgesic efficacy and side effects of modified thoracolumbar interfascial plane block and quadroiliac plane block applied preoperatively in patients…
- Trial name
- NCT07480278
- Testing
- Modified Thoracolumbar Interfascial Plane Block (mTLIP), Quadro-Iliac Plane Block (QIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa City Hospital
Post-operative Pain, Cesarean Section
Post-operative Cesarean Trial of Pain Control
This study plans to learn more about postoperative pain management after cesarean deliveries (C-sections). As a part of standard of care, the Children's Hospital Colorado's Colorado Fetal Care Center (CFCC) follows the standard…
- Trial name
- NCT05131178
- Testing
- ON-Q Pump® with continuous infusion of bupivacaine, ON-Q Pump® with continuous infusion of saline
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Colorado, Denver
Perioperative Analgesia, Hip Replacement, Total
Pericapsular Nerve Group Block Versus Intrathecal Morphine for Analgesia After Total Hip Arthroplasty
The Pericapsular Nerve Group (PENG) block is an effective method for postoperative pain management in patients undergoing primary total hip arthroplasty (THA) via a posterolateral approach.
- Conditions
- Perioperative Analgesia, Hip Replacement, Total, Postoperative Pain, Hip Disease
- Trial name
- NCT07449585
- Testing
- PNEG block, Spinal anesthesia with opioid, Spinal anesthesia without opioid
- Volunteers
- 180 people
- Sponsor
- Medical University of Gdansk
Postoperative Pain, Knee Arthroscopy
Anterior Nerves of the Knee Block Versus Femoral Nerve Block for Knee Arthroscopy
Knee arthroscopy is one of the most common orthopedic procedures, and effective postoperative analgesia is essential for early mobilization and patient comfort.
- Conditions
- Postoperative Pain, Knee Arthroscopy, Analgesia
- Trial name
- ANK-FNB (NCT07910500)
- Testing
- Anterior Nerves of the Knee (ANK) Block, Femoral Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Van Training and Research Hospital
Pain, Postoperative, Pharmacokinetics
Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy
The purpose of this study is to assess pharmacokinetics of liposomal bupivacaine (Exparel) after multilevel intercostal injections of this local anesthetic for pain control during and after thoracoscopic surgeries.
- Trial name
- NCT03737292
- Testing
- Exparel, Bupivacaine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Pain, Postoperative
Post-Op Lidocaine Patch
Randomized control trial evaluating use of lidocaine vs placebo patch for post-operative cesarean incision pain.
- Trial name
- NCT03500211
- Testing
- Lidoderm 5 % Topical Patch
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pain, Acute
Oral Steroid in Controlling Pain After TKA
To compare efficacy of oral steroid in controlling pain after TKA
- Trial name
- NCT04244695
- Testing
- Dexamethasone Oral
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Thammasat University
Pain, Postoperative, Postoperative Hemorrhage
The Effect of Topical Administration of Common Drugs on Postoperative Bleeding and Pain
After surgical procedures, interventions to reduce postoperative pain and bleeding are of great importance. In this study, the effect will be investigated of smearing common drugs, which are designed for injection, directly onto…
- Trial name
- NCT01964781
- Testing
- Tranexamic Acid, Bupivacaine, Adrenaline
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- St. Olavs Hospital
Knee Osteoarthritis
Effect of Noise Control During Total Knee Arthroplasty
Music has emerged as a well-received medical intervention. Patients may be uncomfortable during total joint replacement, which can result in high sedation requirements. These requirements put patients at risk of surgical stress.
- Trial name
- NCT05714267
- Testing
- Active noise cancelling, Passive noice cancelling, Active noise cancelling with music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bezmialem Vakif University
Post-operative Pain
Postoperative Pain in Children Aged From 3 to 5 Years Following Full Mouth Dental Rehabilitation Under General Anesthesia. A Cross-sectional Study. Rehabilitation Under General Anesthesia
the purpose of this study is monitoring Postoperative pain in Children Aged from 3 to 5 years following Full mouth Dental Rehabilitation under General Anesthesia
- Trial name
- NCT03739567
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endoscopic Coblation Adenoidectomy
Coblation and Traditional Adenoidectomy: A Comparative Study
Adenoidectomy is a common pediatric otolaryngologic procedure. While cold curettage remains widely practiced, endoscopic coblation has been developed to enhance precision, minimize intraoperative complications, and reduce…
- Trial name
- NCT07417007
- Testing
- Cold Curettage Adenoidectomy, Coblation-Assisted Adenoidectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Medipol University
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