Clinical trials: Pain Perception
Pain Perception, Root Resorption
The Potential Effect of the Local Administration of Vitamins C and E on Orthodontic Treatment: A Randomized Clinical Trial
Brief Summary of the Study This study investigates the effects of locally administered vitamins C and E on orthodontic tooth movement during the initial stage of treatment.
- Conditions
- Pain Perception, Root Resorption, Rate of Orthodontic Tooth Movement, Biomarkers
- Trial name
- NCT06847880
- Testing
- 1: Vitamin C Supplementation, Vitamin E Supplementation, Saline Solution (Control)
- Where
- 3 sites in Iraq
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Low Back Pain, Life Style
Prognostic Factors of Importance on Who Develops Chronic Low Back Pain
The incidence of low back pain (LBP) is increasing and prognostic factors for developing LBP are unclear. Based on questionnaires, different prognostic factors are being explored over time.
- Conditions
- Low Back Pain, Life Style, Illness Perception
- Trial name
- NCT03940456
- Testing
- Questionnaire
- Where
- Denmark
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- Frederiksberg University Hospital
Histamine, Cowhage
Itch Sensation Induced by Simultaneous Application of Pruritogens (Spatial Summation)
In This experiment, the investigators would like to design a new itch model based on the spatial summation of pruritic stimuli. The hypothesis behind this study (spatial summation) is that two simultaneous applications of…
- Trial name
- NCT06328530
- Testing
- Cowhage, Histamine
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Pain
Comparison Between the Analgesic Effectiveness of Virtual Reality and Topical Anesthesia: A Clinical Study
A split-mouth, controlled trial aimed to clinically compare and evaluate the effectiveness of virtual reality versus topical anesthesia gel prior to administration of dental anesthesia injection in reducing the perceived pain and…
- Trial name
- NCT04919421
- Testing
- Dental injection and topical gel application, Dental injection and virtual reality device
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Neuropathy, Diabetic, Neuropathy, Painful
Methods of Early Detection and Grading Of Diabetic Peripheral Neuropathy (MEDON)
MEDON aims to examine new methods for early detection and grading of diabetic peripheral neuropathy focusing on both small- and large nerve fibers.
- Trial name
- MEDON (NCT04078516)
- Testing
- Perception Threshold Tracking (PTT), Axon-flair mediated respons, Heart rate variability
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Pain, Discomfort
Association Among Pain Perception, Severity of Temporomandibular Joint Dysfunction, and Spinal Health in Caregivers of Stroke Individuals
This study aims to examine pain perception, temporomandibular disorder severity and spine health in caregivers of stroke patients.
- Conditions
- Pain, Discomfort, Caregiver, Temporomandibular Disorder
- Trial name
- NCT06052735
- Testing
- Correlation research
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Perceived Stress, Depression
Online Yoga for Improving the Well-being of Desk-based Workers
The goal of this clinical trial is to evaluate the effectiveness of an 8-week online yoga intervention in improving the well-being and productivity of desk-based workers.
- Conditions
- Perceived Stress, Depression, Anxiety, Mindfulness
- Trial name
- NCT06289426
- Testing
- Yoga
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kingston University
Dental Anxiety
Effectiveness of Auricular Acupuncture in Reducing Dental Anxiety and Pain Perception During Orthodontic Extractions Among Adolescents
This prospective, randomised, double-blinded cross-over study aims to compare the effectiveness of auricular acupuncture (AA) with placebo sham acupuncture (PSA) in reducing dental anxiety, pain perception and physiological…
- Trial name
- NCT06434844
- Testing
- Auricular acupunctures
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Shoulder Pain, Healthy Volunteers
Sensory Processing and Musculoskeletal Shoulder Pain
The development of chronic pain is a common complication in shoulder pain conditions. Half of these type of patients exhibit persistent pain even after a period of six to twelve months from the start of their pain treatment.
- Trial name
- NCT05368649
- Testing
- Short-wave diathermy
- Where
- Argentina
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Gran Rosario
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Orthodontic Appliance Complication
Assessment of Coated Orthodontic Miniscrews With Chlorhexidine Hexametaphosphate Antimicrobial Nanoparticles
Aim To compare between orthodontic miniscrews coated and uncoated with CHX- HMP NP nanoparticles.
- Trial name
- NCT06124235
- Testing
- Coated Orthodontic Miniscrews with Chlorhexidine Hexametaphosphate Nanoparticles, Uncoated Miniscrew with Chlorhexidine Hexametaphosphate Nanoparticles
- Where
- Iraq
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Pain
Mechanism of Human Cold Pain Perception - Involvement of TRPA1, TRPM8, Nav1.7 and Nav1.8
Animal studies suggest that the transient receptor potential ion channels TRPM8 and TRPA1 are cold sensors and that sodium channels Nav1.8 and Nav1.7 are essential for detecting pain induced by cold temperatures.
- Trial name
- NCT05935280
- Testing
- Room temperature, Cold temperature, Lidocain
- Where
- Austria
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Dental Phobia, Dental Anxiety
Assessment of Pain, Anxiety and Efficiency of NumBee Compared to Traditional Local Anesthetic Syringe
The study was conducted among a group of dental patients aged (6-8 years old) of both genders to assess the following variables in the needleless interparliamentary anesthesia (NUMBEE) compared to traditional local anesthesia: 1.
- Conditions
- Dental Phobia, Dental Anxiety, Anesthesia, Local, Needle Phobia
- Trial name
- NCT05899296
- Testing
- dental syringe ( NumBee), Traditional dental syringe
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Duaa Kamal Naji
Experimental Pain in Healthy Human Subjects
How do Alpha Oscillations Shape the Perception of Pain? - An EEG-based Neurofeedback Study
Pain is closely linked to alpha oscillations (8 -13 Hz) which are thought to represent a supra-modal, top-down mediated gating mechanism that shapes sensory processing.
- Trial name
- NCT05570695
- Testing
- attention right training, ARTNF, attention left training, ALTNF
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Healthy
Oxytocin's Effect on Social Pain Empathy
The aim of the present experiment is to examine oxytocin's behavioral and neural effects on social pain empathy
- Trial name
- NCT03122067
- Testing
- oxytocin treatment
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Postoperative Pain, Patient Satisfaction
Post Operative Analgesia and Patient Satisfaction
To understand how patients perceive the quality of care they receive when given different post-operative analgesic medications. Specifically the investigators want to assess whether patients who receive non-opioid analgesia…
- Conditions
- Postoperative Pain, Patient Satisfaction, Analgesia
- Trial name
- NCT04976387
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Pregnancy, Vaginal Delivery
The Effect of Therapeutic Touch at Birth on Pain, Birth Duration, Traumatic Birth Perception and Anxiety
Aim: This study was planned to determine the effect of therapeutic touch applied at birth on pain, birth duration, traumatic birth perception and anxiety.
- Trial name
- NCT06426329
- Testing
- Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Musculoskeletal Diseases, Occupational Diseases
Impact of Exoskeleton Use on Perceived Effort and Pain During Resident Handling in Nursing Home Care Staff
The EXO 2 study assessed whether daily use of an exoskeleton - a wearable mechanical support device - could reduce physical effort and pain in nursing home care staff who regularly perform resident handling tasks such as bed…
- Conditions
- Musculoskeletal Diseases, Occupational Diseases, Low Back Pain, Occupational Health
- Trial name
- Exo 2 (NCT07757737)
- Testing
- Passive back-assist exoskeleton (HAPO Version 4)
- Where
- 5 sites in France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- LNA SANTE
Pain
Sedation and Pain (The Effect of IV Sedation on Pain Perception)
The investigators propose to evaluate the potential effect of sedation on pain perception in two ways, by asking for a participant's pain rating(subjective) and by evaluating a subject's brain activation using fMRI(objective).
- Trial name
- NCT00853333
- Testing
- dexmedetomidine, midazolam, propofol
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pain
Pain Perception With Tenaculum Placement
Randomized controlled trial that compares methods of tenaculum placement during intrauterine device insertion and their effect on pain.
- Trial name
- NCT02969421
- Testing
- Cough method for placement of tenaculum, Slow Tenaculum Placement of tenaculum
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Duke University