Clinical trials: Palliative Cancer
Activities of Daily Living, Everyday Activities
The Cancer Home Life Intervention Study. A Randomised, Controlled Multicentre Trial and a Health Economic Evaluation
The purpose of this study is to examine the effectiveness and cost-effectiveness of the Cancer Home Life Intervention compared to usual care on performance of and participation in everyday activities and quality of life in people…
- Conditions
- Activities of Daily Living, Everyday Activities, Palliative Care, Cancer
- Trial name
- NCT02356627
- Testing
- The Cancer Home Life Intervention
- Where
- 2 sites in Denmark
- Volunteers
- 242 people
- Sponsor
- University of Southern Denmark
Breast Cancer, Cancer Survivorship
AI-Based Symptom Management for Post-Treatment Breast Cancer Survivors
This pilot randomized controlled trial will test the feasibility and acceptability of an Artificial Intelligence-based Multidimensional Symptom Management (AIMS) intervention for post-treatment breast cancer survivors.
- Trial name
- AIMS-BC (NCT07770243)
- Testing
- AIMS platform
- Volunteers
- 36 people
- Sponsor
- Hong Kong Metropolitan University
Breast Cancer
Breast Cancer Registry Platform
The purpose of the project is to set up a national, prospective, longitudinal, multicenter cohort study with associated satellites, a tumor registry platform, to document uniform data on characteristics, molecular diagnostics…
- Trial name
- OPAL (NCT03417115)
- Where
- Germany
- Volunteers
- 6,150 people
- Sponsor
- iOMEDICO AG
Critical Illness, Chronic Disease
Improving Communication About Serious Illness
The purpose of this study is to improve care delivered to patients with serious illness by enhancing communication among patients, families, and clinicians in the outpatient setting.
- Conditions
- Critical Illness, Chronic Disease, Terminal Care, Palliative Care
- Trial name
- ICSI (NCT01933789)
- Testing
- Communication Feedback Form for Patients with Serious Illness
- Where
- 6 sites in United States
- Volunteers
- 817 people
- Sponsor
- University of Washington
Malignant Brain Tumors
PRESENCE Project: An Early Palliative Care Intervention in Brain Tumors
The purpose of this pilot study is to investigate the feasibility of an early palliative care intervention (PRESENCE: Providing Resources Education, Support, and Enabling New brain tumor patients to Cope Effectively) and the…
- Trial name
- NCT01652768
- Testing
- Research Questionnaires, Palliative Care Team, Educational Information Session for Patients and Caregivers
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Multiple Organ Failure, End Stage Cardiac Failure
Timing of Acute Palliative Care Consultation in Critically Ill Patients
A prospective randomized controlled trial studying the ordering of palliative care consultations in the emergency department (Ig) versus later palliative care consultations in the hospital--ICU or hospital ward(Cg).
- Conditions
- Multiple Organ Failure, End Stage Cardiac Failure, End Stage Chronic Obstructive Airways Disease, Chronic Kidney Disease Stage 5
- Trial name
- NCT02858778
- Testing
- Early order of palliative care consultation
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Wayne State University
Unspecified Adult Solid Tumor, Protocol Specific
Extracranial Stereotactic Radiosurgery in Treating Patients With Solid Tumors
RATIONALE: Extracranial stereotactic radiosurgery may be able to send x-rays directly to the tumor and cause less damage to normal tissue.
- Trial name
- NCT00311597
- Testing
- Radiosurgery
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Wake Forest University Health Sciences
Head and Neck Cancer, Supportive Care
Assessing Impact of CCO's PSO & PC Pathway in Ambulatory HNC Clinics
Rates of depression and anxiety in cancer patients are much higher compared to the general population. 40% of head and neck cancer patients will develop significant distress along the cancer journey.
- Trial name
- NCT03266276
- Testing
- PSOPC pathway approach
- Where
- Canada
- Volunteers
- 98 people
- Sponsor
- Sunnybrook Health Sciences Centre
Neoplasms Malignant, Carcinoma
Existential Distress in Patients with Advanced Cancer and Their Caregivers
Despite the potential for alleviation of existential distress through psychosocial interventions, existential concerns and their impact on health care outcomes of patients and caregivers have not yet been systematically studied.
- Conditions
- Neoplasms Malignant, Carcinoma, Palliative Care
- Trial name
- NCT04600206
- Testing
- Self-report questionnaires
- Where
- 5 sites in Germany
- Volunteers
- 800 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pain
Coaching to Improve Care of Cancer Pain
An estimate of 90% of patients with cancer experience at least moderate pain at some point in their illness, and 42% of patients do not receive adequate palliation.
- Trial name
- NCT00283166
- Testing
- Tailored Education and Coaching
- Where
- 3 sites in United States
- Volunteers
- 258 people
- Sponsor
- University of California, Davis
Bone Metastases in Subjects With Advanced Cancer, Radiotherapy
Timely Integration of Palliative Care in Oncology Care for Patients Referred for Palliative Radiotherapy on Bone Metastases: A Randomized Trial
Rationale: With improvements in systemic tumour-directed treatments for primary tumours, survival rates for patients with bone metastases are improving.
- Trial name
- TIPZO-RT (NCT06805396)
- Testing
- Palliative Care Consult
- Where
- 5 sites in Netherlands
- Volunteers
- 246 people
- Sponsor
- Roxanne Gal
Survivorship, Breast Cancer
The LYSA (Linking You to Support and Advice) Trial
This study's aim is to evaluate the feasibility of introducing a women's malignancy survivorship clinic incorporating symptom management through ePRO collection (complex intervention) into routine follow up care in patients with…
- Conditions
- Survivorship, Breast Cancer, Cervical Cancer, Endometrial Cancer
- Trial name
- LYSA (NCT05035173)
- Testing
- Survivorship Clinic Assessments, Survivorship Clinic Nurse Resource, Survivorship Clinic Dietitian Resource
- Where
- Ireland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University College Cork
Esophageal Cancer
trūFreeze® Palliative Esophageal Cancer
Prospective, open label, non-controlled single arm, multi-center study The primary objective is to study the effects of the trūFreeze® Spray Cryotherapy System in a population of subjects who have been diagnosed with persistent…
- Trial name
- NCT03243734
- Testing
- trūFreeze® System spray cryotherapy
- Where
- 10 sites in United States
- Volunteers
- 49 people
- Sponsor
- US Endoscopy Group Inc.
Metastatic Disease
MAnagement of METastatic Disease in Campania (MAMETIC)
The MAMETIC Trial represents the first regional epidemiological study that aims to evaluate patients living in Campania with metastatic cancer, with the intent to detect different prevalence of tumors in the metastatic phase and…
- Trial name
- MAMETIC (NCT04595032)
- Testing
- 3DCRT, IMRT, VMAT, SBRT
- Where
- Italy
- Volunteers
- 3,234 people
- Sponsor
- National Cancer Institute, Naples
Advanced Cancer
Cancer End Of Life Evaluation
The aim of this study is to culturally adapt and to validate Quality Of Life tools dedicated to the end of life for French cancer patients.
- Trial name
- CEOLE (NCT01545921)
- Testing
- Quality Of Life questionnaires completion
- Where
- 10 sites in France
- Volunteers
- 179 people
- Sponsor
- Institut Cancerologie de l'Ouest
Palliative Care, Cancer
Mobile Health Application for Family Caregivers in Home Palliative Care
Family caregivers play a central role in providing daily care for patients receiving home palliative care. However, caregiving responsibilities may lead to increased burden, stress, and difficulties in symptom management and care…
- Conditions
- Palliative Care, Cancer, Caregiver
- Trial name
- CARE-Mobile (NCT07654998)
- Testing
- Mobile Health Application
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kutahya Health Sciences University
Chronic Pain, Cancer Pain
UDOPAL Study: Home-Based Interventional Approach to Pain Management in Home-Hospitalized Patients
The UDOPAL Study proposes an innovative home-based care approach for the management of pain in patients admitted to the Home Hospitalization Unit (UHD).
- Conditions
- Chronic Pain, Cancer Pain, Neuropathic Pain, Palliative Care
- Trial name
- UDOPAL (NCT07265492)
- Testing
- UDOPAL model
- Volunteers
- 100 people
- Sponsor
- Hospital de Manises
Metastatic Cancer, Palliative
Patient Reported Outcomes/Metrics Program Trial
This is an observational study to investigate if it is feasible to recruit 100 patients receiving radiotherapy (RT) to metastatic disease to wear Hexoskin and if Hexoskin will facilitate the monitoring, detection and early…
- Trial name
- PROMPT (NCT04983199)
- Testing
- Hexoskin Medical System
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Stage IV Non-small Cell Lung Cancer, Targeted Therapy
Patient-centered, Optimal Integration of Survivorship and Palliative Care
The goal of this study is to develop and test the feasibility of a supportive care model (POISE) for patients with metastatic Non-small Cell Lung Cancer (NSCLC).
- Conditions
- Stage IV Non-small Cell Lung Cancer, Targeted Therapy, Nonsmall Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung
- Trial name
- NCT04900935
- Testing
- POISE
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Massachusetts General Hospital
Frailty, Oncology Problem
PATH Program for for Severely Frail or Cognitively Impaired Patients Scheduled for Cancer Surgery.
This is a single center, non-blinded randomized control trial taking place at the Queen Elizabeth II hospital (QEII) in Nova Scotia.
- Conditions
- Frailty, Oncology Problem, Cognitive Impairment
- Trial name
- NCT06022666
- Testing
- Geriatric assessment
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Nova Scotia Health Authority
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