Clinical trials: Palliative Cancer
Advanced Cancer, Palliative
Physiotherapy Effects on Function, Ambulation, and Independence in Palliative Cancer Care
This study examines the short-term effects of physiotherapy on functional status, ambulation, and independence among patients admitted to the palliative care unit at Jazan Specialist Hospital.
- Trial name
- NCT07654933
- Testing
- Experimental: Physiotherapy Intervention Group
- Where
- Saudi Arabia
- Volunteers
- 32 people
- Sponsor
- University of Jazan
Cancer, Palliative Care
Music Therapy Program for Patients in Palliative Care (MUSPAL360)
Hospitalized patients with advanced cancer often experience a heavy burden of physical, emotional, and spiritual symptoms that affect their quality of life.
- Trial name
- NCT07831148
- Testing
- Music Therapy with Virtual Reality (Session 1), Significant Song Choice (Session 2), Biographical Musical Legacy (Session 3)
- Volunteers
- 40 people
- Sponsor
- Austral University, Argentina
Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
Learning Collaborative Versus Technical Assistance in Delivering a Palliative Care Program to Patients With Advanced Cancer and Their Caregivers
This trial studies the delivery of the ENABLE palliative care program by two different methods called a Virtual Learning Collaborative or Technical Assistance for patients with advanced cancer and their caregivers.
- Conditions
- Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm
- Trial name
- NCT04062552
- Testing
- Behavioral, Psychological or Informational Intervention, Educational Intervention, Medical Examination Assessment
- Where
- 113 sites in United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Rochester NCORP Research Base
Cancer, Thoracic Neoplasms
Improving Cancer On-treatment Symptom Management
Patient-reported outcome measures (PROMs) is an umbrella term that refers to any report on a health status measure that is reported directly by the patient, without the influence of clinicians or anyone else.
- Conditions
- Cancer, Thoracic Neoplasms, Gastrointestinal Cancer, Lung Cancer
- Trial name
- IMPROVE (NCT04589247)
- Where
- 4 sites in United States
- Volunteers
- 104 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Metastatic Cancer, Mobile Health
Mobile Health Technology for Palliative Care Patients
To test the potential and acceptance of wireless activity tracking in palliative care patients leaving hospital care. Explorative study, collaboration project of the Clinic of Radiation-Oncology, University Hospital Zurich and…
- Conditions
- Metastatic Cancer, Mobile Health, Chronic Disease
- Trial name
- NCT03038841
- Testing
- Mobile Health
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Head And Neck Cancer
Symptom Burden in Head and Neck Cancer
The goal of this clinical research study is to compare armodafinil, bupropion, and minocycline when given alone or in combination.
- Trial name
- NCT01219673
- Testing
- Armodafinil, Minocycline, Bupropion
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- M.D. Anderson Cancer Center
Oral Cancer, Palliative Supportive Care
Early Palliative Care For Patients With Oral Cancer in Sri Lanka
The goal of this quasi experimental study is to develop and assess the effectiveness of an early palliative care intervention in patients with oral cancer in Sri Lanka.
- Conditions
- Oral Cancer, Palliative Supportive Care, Psychological Distress, Quality of Life of Patients
- Trial name
- NCT06726317
- Testing
- Early palliative care integration
- Where
- 4 sites in Sri Lanka
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Colombo
Cancer, Metastatic, Family Members
An Upstream Palliative Care Intervention for Rural and African-American Advanced Cancer Family Caregivers
The burden placed on advanced cancer family caregivers (FCGs) and the toll on their mental and physical health have never been greater and is particularly pernicious for underserved groups in the Southeastern U.S., including…
- Trial name
- NCT03464188
- Testing
- Project Cornerstone
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Alabama at Birmingham
Colon Cancer, Rectal Cancer
Developing an mHealth Application to Improve Cancer Chemotherapy Symptom Management
This research project addresses critical gaps in cancer symptom management through the creation of a mobile chemotherapy symptom management application.
- Trial name
- NCT02460822
- Testing
- MyChemoCare iPad application
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Michigan
mCRC
Radiotherapy Combined QL1706, TAS-102 and Bevacizumab in mCRC
This single-center, single-arm, prospective study plans to enroll patients with advanced colorectal cancer who have failed first-line or higher systemic therapies.
- Trial name
- NCT07116577
- Testing
- Palliative radiotherapy, Iparomlimab and tuvonralimab, TAS-102
- Where
- China
- Volunteers
- 37 people
- Sponsor
- Jinan Central Hospital
Family, End of Life
Web-based Support for Family Caregivers of Patients With Advanced Cancer
For family caregivers of patients with advanced cancer, preparedness for caregiving is crucial for maintaining health and quality of life both during care and after the death of the patient.
- Conditions
- Family, End of Life, Cancer Metastatic, Chronic Illness
- Trial name
- NCT05785494
- Testing
- Narstaende.se
- Where
- Sweden
- Volunteers
- 204 people
- Sponsor
- Ersta Sköndal University College
Depression, Anxiety, Metastatic Cancer
Randomized Clinical Trial of a Multi-Modal Palliative Care Intervention
Adults diagnosed with metastatic cancer commonly experience depression and anxiety symptoms, which can interfere with advance care planning.
- Trial name
- NCT04773639
- Testing
- Multi-Modal Palliative Care Intervention, Usual Care Control Condition
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Colorado, Boulder
Esophageal Neoplasms, Dysphagia
Comparative Study Between (FC-SEMS) and (PC-SEMS) in the Palliation of Dysphagia Due to Malignant Neoplasm of Esophagus.
Esophageal cancer is the seventh most common type of cancer in the world, with an estimated global incidence of 604,100 new cases per year. The main symptom of esophageal cancer is dysphagia, associated or not with weight loss.
- Trial name
- NCT06070376
- Testing
- Fully Covered Esophageal Prosthesis (FC-SEMS), Partially Covered Esophageal Prosthesis (PC-SEMS)
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Non-small Cell Lung Carcinoma
Observing Patients With Palliative Asymptomatic Centrally Located Advanced Non-small Cell Lung Carcinoma (NSCLC)
The aim of the study is to assess current practice within PROP \& lung teams, for treating asymptomatic patients with centrally located non-small cell lung cancer (NSCLC), and to observe outcomes for those patients receiving…
- Trial name
- NCT01279408
- Testing
- None: Questionnaire Study
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- University Health Network, Toronto
Life-limiting Cancer With Prognosis of Approximately 1 Year
Effect of Early Palliative Care on Quality of Life of Patients With Advanced Cancer: a Randomised Controlled Trial.
The World Health Organization (WHO) defines palliative care as an approach to improve the quality of life of patients and their families facing life-threatening illness, through prevention and relief of pain and of physical…
- Trial name
- IPaC (NCT01865396)
- Testing
- Interventional palliative care, Standard oncologic care
- Where
- Belgium
- Volunteers
- 268 people
- Sponsor
- University Ghent
Advanced NSCLC, First Line Treatment
POSITIVE - Study (Part III) Heidelberg
The investigators plan to evaluate, in a randomized, controlled phase III trial in patients with advanced non-small cell lung cancer (NSCLC), the effects of a 24-week exercise intervention program (EIP) on quality of life…
- Trial name
- POSITIVE (NCT02055508)
- Testing
- Exercise Intervention, Care-Management-Phone-Calls
- Where
- Germany
- Volunteers
- 232 people
- Sponsor
- German Cancer Research Center
Upper Abdominal Malignancies, Upper Gastrointestinal Cancer
Comparison of CT-Guided Celiac Plexus Neurolysis and Pharmacotherapy
After enrolment, patients were randomly assigned to two groups by means of a lottery procedure, whereby each patient blindly chose one of two labelled slips, resulting in group assignment to receive.
- Trial name
- NCT07761650
- Testing
- CT-guided celiac plexus neurolysis, Standard pharmacotherapy
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Mayo Hospital Lahore
Palliative Care, Caregivers
A Problem-Solving Intervention for Family Caregivers in Palliative Oncology
In congruence with the National Cancer Institute's commitment to supporting families of individuals with cancer across the full disease trajectory, the investigators seek to examine the feasibility of a technologically-mediated…
- Conditions
- Palliative Care, Caregivers, Medical Oncology
- Trial name
- NCT02427490
- Testing
- Problem-Solving Intervention, Unenhanced Monitoring
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Biliary Tract Neoplasms, Pancreatic Neoplasms
RCT Steel (Wallstent®) vs Nitinol (Wallflex®) Bile Duct Stent for Palliation of Malignant Obstruction
Less than 20% of patients with malignant distal bile duct (BD) obstruction (often pancreatic cancer) are suitable for resection surgery.In the rest,palliation treatment comes into focus.
- Conditions
- Biliary Tract Neoplasms, Pancreatic Neoplasms, Stent Occlusion
- Trial name
- NCT00980889
- Testing
- Steel, Nitinol
- Where
- 11 sites in Sweden
- Volunteers
- 400 people
- Sponsor
- Stockholm South General Hospital
Advanced Gastric or EGJ Cancer
Ramucirumab Plus FOLFIRI Versus Ramucirumab Plus Paclitaxel in Patients With Advanced or Metastatic Gastric Cancer, Who Failed One Prior Line of Palliative Chemotherapy
This clinical trial will evaluate whether it is beneficial in terms of prolongation of survival to combine FOLFIRI (standard treatment) with ramucirumab compared to the standard treatment of ramucirumab plus paclitaxel in…
- Trial name
- RAMIRIS (NCT03081143)
- Testing
- FOLFIRI, Ramucirumab, Paclitaxel
- Where
- 16 sites in Austria, Germany and 1 more
- Volunteers
- 429 people
- Sponsor
- Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
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