Clinical trials: Pancreatic Stent
Biliary Stricture, Chronic Pancreatitis
Endoscopic Treatment of Biliary Stricture Caused by Chronic Pancreatitis
Benign biliary strictures can be endoscopically treated with plastic or self-expandable metal stents (SEMS). The purpose of the prospective randomized study is to compare the safety and feasibility of covered SEMS with multiple…
- Trial name
- NCT01085747
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Helsinki University Central Hospital
Cholangiocarcinoma, Pancreas Cancer
RFA for Malignant Biliary Obstruction
Pancreatic cancer and cholangiocarcinoma are the most common causes of malignant biliary obstruction. They are diseases of increasing incidence and unfavorable prognosis.
- Trial name
- NCT03166436
- Testing
- Radiofrequency ablation, Biliary stenting
- Where
- Czechia
- Volunteers
- 140 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Post-ERCP Acute Pancreatitis, Non-steroid Anti-inflammatory Drugs
Rectal NSAIDs With/Without PD Stent for PEP Prevention
Pancreatitis is the most common and serious complication following post-endoscopic retrograde cholangiopancreatography (ERCP) and is associated with occasional mortality, extended hospital stays, and increased healthcare…
- Conditions
- Post-ERCP Acute Pancreatitis, Non-steroid Anti-inflammatory Drugs, Pancreatic Duct Stent Placement
- Trial name
- NCT07117318
- Testing
- NSAIDs, NSAIDs plus PDS
- Where
- 15 sites in China
- Volunteers
- 1,278 people
- Sponsor
- Air Force Military Medical University, China
Unresectable Pancreatic Cancer, Cholangiocarcinoma Non-resectable
RFA RCT for Pancreatic or Bile Duct Cancer
Malignant obstructive jaundice is a common complication of advanced stage pancreatic adenocarcinoma and cholangiocarcinoma. Over 50% of common bile duct (CBD) obstructions are due to malignancy, and the majority of neoplasms are…
- Trial name
- RFARCT (NCT02166190)
- Testing
- Radiofrequency Ablation using EndoHPB Probe, Stenting only
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Weill Medical College of Cornell University
Post-ERCP Acute Pancreatitis, Pancreatic Duct Stricture
Short Term Pancreatic Stenting Registry
The purpose of this study is to document clinical utility and distribution of indications for short term pancreatic stenting, and stent type preference by indication at tertiary referral centers with expertise in pancreatic…
- Conditions
- Post-ERCP Acute Pancreatitis, Pancreatic Duct Stricture, Pancreatic Duct Stones, Pancreatic Duct Leakage
- Trial name
- NCT02262845
- Testing
- The Advanix™ Pancreatic Stent and NaviFlex RX Pancreatic Delivery System and Pushers
- Where
- 7 sites in United States, Germany and 2 more
- Volunteers
- 246 people
- Sponsor
- Boston Scientific Corporation
Pancreatic Collection
Lumen Apposing Metal Stents With and Without a Double Pigtail Stent in Pancreatic Collections
The study evaluates the security of LAMS with ando without a coaxial double pigtail plastic stent in the management of pancreatic fuid collections.
- Trial name
- NCT03282539
- Testing
- LAMS, LAMS + pigtail
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- Hospital Universitari de Bellvitge
Pancreatic Fistula
Prophylactic Pancreatic Stent for the Prevention of Post Operative Pancreatic Fistula
Postoperative pancreatic fistula (POPF) remains one of the most harmful complications after pancreatic resection. Some studies have indicated that endoscopic pancreatic stenting was effective in the treatment of POPF.
- Trial name
- NCT03822676
- Testing
- Prophylactic pancreatic stent
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Peking Union Medical College Hospital
Acute Pancreatitis
PROTon Pump Inhibitors and Stent OCclusion Rate Of Lumen Apposing Metal Stents
The goal of this observational retrospective cohort study in combination with an expert study is to assess the clinical relevance and management of Lumen apposing metal stent (LAMS)-occlusion and LAMS-occlusion-related…
- Trial name
- PROTOCOL (NCT05817721)
- Testing
- Proton pump inhibitor, LAMS-implantation
- Where
- Germany
- Volunteers
- 893 people
- Sponsor
- University Medical Center Goettingen
Pancreatic Cancer, Unresectable Biliary-pancreatic Malignancies
Endoscopic Biliary Co-axial Stent Placement Plus/Minus Use of Radiofrequency Ablation (RFA) for Clearance of Occluded Self Expandable Metal Stents (SEMS) in Patients With Distal Biliary Obstruction From Unresectable Biliary-pancreatic Malignancies
The purpose of this study is to compare the effects good and/or bad of combining radiofrequency ablation with placement of a second stent, versus a second stent alone.
- Trial name
- NCT02340728
- Testing
- ERCP with SEMS plus radiofrequency ablation, ERCP with SEMS alone (standard of care)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Biliary Obstruction, Pancreatic Cancer
LAMS Choledochoduodenostomies: With or Without Coaxial Plastic Stent
The aim of the study is to evaluate technical, clinical and safety outcomes of lumen-apposing metal stent (LAMS) with and without a coaxial double-pigtail plastic stent (DPS) in EUS-guided choledochoduodenostomies (CDS) for the…
- Conditions
- Biliary Obstruction, Pancreatic Cancer, Biliary Tract Neoplasms
- Trial name
- BAMPI (NCT04595058)
- Testing
- Double pigtail plastic stent through lumen-apposing metal stent, Lumen-apposing metal stent without double pigtail plastic stent
- Where
- 2 sites in Spain
- Volunteers
- 123 people
- Sponsor
- Hospital Universitari de Bellvitge
Chronic Pancreatitis, Benign Biliary Stricture
Single Plastic Stent Vs. Fully Covered Self-Expanding Metal Stent on Benign Biliary Stricture Secondary to Chronic Pancreatitis
The goal of this clinical trial is to compare the efficacy and safety of a single plastic stent versus a fully covered self-expanded metal stent in relieving benign biliary stricture secondary to chronic pancreatitis.
- Trial name
- ESSENCE (NCT06655051)
- Testing
- endoscopic retrograde biliary drainage (single plastic stent), endoscopic retrograde biliary drainage ( fully covered self-expanding metal stent)
- Where
- China
- Volunteers
- 134 people
- Sponsor
- Changhai Hospital
Cholangiopancreatography, Endoscopic Rretrograde, Post-ERCP Pancreatitis
Early Pancreatic Stent Placement for Preventing PEP
Our aim is to compare early versus late pancreatic stent placement in preventing PEP among patients with naive papilla. The EVL trial will provide essential answers regarding the optimal timing of prophylactic pancreatic stent…
- Trial name
- EVL (NCT06250803)
- Testing
- early pancreatic stent placement (EPSP)
- Where
- 2 sites in China
- Volunteers
- 768 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Pancreatic Pseudocyst
Clinical Evaluation of Enteral-extended Anti-reflux Stents for Pancreatic Pseudocyst
At present, endoscopic therapy is the preferred method to solve biliary or pancreatic diseases. And EUS-guided stent implantation and drainage of pancreatic pseudocyst is the main method in Endoscopic treatment of pancreatic…
- Trial name
- NCT05716594
- Testing
- Plant enteral-extended anti-reflux stents, Plant traditional stents
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Peking University Third Hospital
Biliary Tract Diseases
Plastic vs Biodegradable Pancreatic Stent in Post-ERCP Pancreatitis Prevention
Multiple risk factors have been linked with post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP); therefore, it is critical to follow strategies to reduce associated risk, morbidity, and mortality.
- Trial name
- NCT05307861
- Testing
- Pancreatic duct stenting with plastic stent, Pancreatic duct stenting with Biodegradable Stent
- Where
- Ecuador
- Volunteers
- 98 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Biliary Stricture, Chronic Pancreatitis
Covered Metal Stent for Benign Biliary Stricture Caused by Chronic Pancreatitis
Benign biliary strictures caused by chronic pancreatitis can be endoscopically treated with covered self-expandable metal stents (cSEMS).The purpose of the prospective randomized study is to define the optimal duration of…
- Trial name
- NCT01929538
- Testing
- ERCP, covered self-expanding biliary metal stent, 12mm in diameter, covered self-expanding biliary metal stent, 10mm in diameter
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Helsinki University Central Hospital
Pancreas Disease, Fistula Pancreatic
Prevention of CR-POPF in PD With the Technique of Connexion the Pancreatic Duct to Jejunum Stented (CONDUCTJE-ST).
Objective: To assess the efficacy of the "connexion pancreatic duct to jejunum stented (CONDUCTJE-ST)" technique to prevent clinically relevant postoperative pancreatic fistula (CR-POPF) after pancreaticoduodenectomy (PD).
- Trial name
- CONDUCTJE-ST (NCT04898517)
- Testing
- Pancreaticoduodenectomy with the CONDUCTJE-ST technique
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Bile Duct Obstruction, Pancreatic Cancer
Biliary Metal Stent Study: Metal Stents for Management of Distal Malignant Biliary Obstruction
The primary purpose is to compare patency of two different types of biliary metal stents, i.e. covered versus uncovered Nitinella metal stent. Secondary purposes are to determine frequency of complications in the two groups, e.g.
- Conditions
- Bile Duct Obstruction, Pancreatic Cancer, Gallbladder Cancer, Bile Duct Cancer
- Trial name
- NCT00280709
- Testing
- "Nitinella" ; SX-ELLA Stent Biliary (biliary metal stent)
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- University Hospital, Linkoeping
Severe Acute Pancreatitis, Pancreatic Necrosis
Percutaneous Continuous Irrigation Combined With Transgastric Necrosectomy usingLAMS in Treatment of SAP
Severe acute pancreatitis (SAP) is the most severe form of acute pancreatitis (AP) and Infection of pancreatic necrosis (IPN) have shown to be one of the decisive factors defining the severity of illness.
- Trial name
- PCISLAMS (NCT05508828)
- Testing
- Percutaneous Continuous Irrigation assisted Vacuum Drainage Combined With Transgastric Necrosectomy
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Chinese Medical Association
Cholelithiasis Associated With Common Bile Duct Stones
Prophylactic PS Placement to Prevent Pancreatitis After Endoscopic Transpapillary GPC for Cholelithiasis With Concomitant Choledocholithiasis
In this multicenter, randomized trial, patients with cholelithiasis with concomitant choledocholithiasis based on inclusion and exclusion criteria will be randomly assigned to receive rectal indomethacin alone or the combination…
- Trial name
- NCT07495111
- Testing
- Prophylactic pancreatic stent, rectal indomethacin alone
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Qilu Hospital of Shandong University
Malignant Bilio-pancreatic Diseases
Feasibility and Safety of a Dedicated Biliary Stent for Transmural EUS-guided Hepatico-gastrostomy: the FIT Study
One of the major roles of interventional EUS is biliary drainage (EUS-BD) as an alternative to ERCP-based biliary decompression. In fact, even when performed by expert endoscopists, ERCP-based stenting fails in 5% of cases.
- Trial name
- FIT (NCT04403893)
- Testing
- HANARO biliary stent placement
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Clinico Humanitas