Clinical trials: Paracentesis, open to volunteers
Bariatric or General Abdominal Surgeries, Bariatric Surgery Patients
TAP Block Timing Study
This study investigates whether administering TAP blocks pre-incision provides superior postoperative pain control and reduces opioid use along with other medications compared to post-incision administration in patients…
- Trial name
- NCT07064200
- Testing
- TAP Block
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Weill Medical College of Cornell University
Postoperative Pain, Midline Laparotomy
Analgesic Outcomes of Ultrasound-Guided QLB vs TAP Block in Midline Laparotomy
This randomized controlled trial compares the analgesic efficacy of ultrasound-guided bilateral lateral quadratus lumborum block (QLB, QL1) versus ultrasound-guided bilateral transversus abdominis plane (TAP) block in adults…
- Conditions
- Postoperative Pain, Midline Laparotomy, Abdominal Surgery
- Trial name
- NCT07796828
- Testing
- Ultrasound-Guided Lateral Quadratus Lumborum Block (QL1), Ultrasound-Guided Transversus Abdominis Plane Block, Bupivacaine 0.25%
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Sheikh Zayed Medical College
Postoperative Pain, Total Abdominal Hysterectomy
Dexmedetomidine Versus Ketamine in TAP Block for Postoperative Analgesia After Total Abdominal Hysterectomy
Total abdominal hysterectomy is associated with significant postoperative pain due to abdominal wall incision and tissue manipulation.
- Trial name
- NCT07845643
- Testing
- TAP block using Dexmedetomidine & Bupivacaine, TAP block using Ketamine Hydrochloride and Bupivacaine
- Where
- Bangladesh
- Volunteers
- 64 people
- Sponsor
- Bangladesh Medical University
Cirrhosis, Spontaneous Bacterial Peritonitis
Early Ascitis Parencentesis in SBP
Paracentesis at 48 hours, as recommended in international guidelines, could delay the time to effective antibiotic therapy in cases of SBP with germs resistant to empirical antibiotic therapy.
- Trial name
- PAPISLA (NCT06679842)
- Testing
- ascitis paracentesis
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Laparoscopic Cholecystectomy, Postoperative Pain
Comparison of ANI Between Preoperative and Postoperative Ultrasound-guided TAP Block in Laparoscopic Cholecystectomy
The goal of this clinical trial is to learn if the timing of ultrasound-guided transversus abdominis plane block (US-TAP block) administration (preoperative vs.
- Trial name
- CholeANI (NCT07809009)
- Testing
- Preoperative US-TAP Block, Postoperative US-TAP Block
- Volunteers
- 120 people
- Sponsor
- Pusan National University Yangsan Hospital
Pain, Postoperative, Opioid Use
"Dexa vs Dexmedetomidine With Bupivacaine in TAP Block for Laparotomy Analgesia
Transversus abdominis plane block is a regional anesthetic technique which blocks the abdominal neural afferents by introducing local anesthetic into the neuro-fascial plane between the internal oblique and the transversus…
- Conditions
- Pain, Postoperative, Opioid Use, Laparotomy
- Trial name
- NCT07590752
- Testing
- Bupivacaine Hcl 0.25% Inj_#1, Bupivacaine Hcl 0.25% Inj_#2
- Where
- Pakistan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal
Pain Management After Surgery
Open TAP-block in Pediatric Abdominal Surgery
The goal of this trial is to evaluate an open TAP-block vs continuous administration of local anestetic via a wound catheter for postoperative pain management in patients 1-15 years of age undergoing open abdominal surgery.
- Trial name
- NCT07352683
- Testing
- TAP-block, Wound catheter
- Where
- Sweden
- Volunteers
- 88 people
- Sponsor
- Uppsala University
Ascites, Paracentesis
Medical-economic Evaluation of the Care of Refractory Ascites by Implantation of Alfapump® Device in Cirrhotic Patients
The hypothesis is that the Alfapump® strategy would be more effective in terms of QALYs generated , and that the cost of Alfapump® device and its implantation will be totally or partially offset by the reduction in the number of…
- Conditions
- Ascites, Paracentesis, Cirrhosis
- Trial name
- ARIAPUMP (NCT03506893)
- Testing
- Alphapump, Ascites puncture
- Where
- 10 sites in France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Grenoble
Pain Management, Hysterectomy
Comparison of Sensory Block Coverage and Clinical Effectiveness of TAP and Rectus Sheath Blocks in Pfannenstiel Incisions
Hysterectomy is one of the most common major gynecologic surgeries performed for various indications, and hundreds of thousands of procedures are carried out annually, particularly in developed countries.
- Trial name
- NCT07260396
- Testing
- Group Transversus Abdominis Plane Block, Group Rectus Sheath Block
- Volunteers
- 30 people
- Sponsor
- Samsun University
Obesity, Bariatric Surgery
Opioid-Free Versus Opioid-Based Anesthesia in Bariatric
This study is designed as a prospective, randomized, controlled clinical trial. It will be conducted in the operating rooms of the University of Health Sciences, Diyarbakır Gazi Yaşargil Training and Research Hospital.
- Trial name
- NCT07105839
- Testing
- Intraoperative rescue analgesia, Intraoperative rescue analgesia:
- Volunteers
- 50 people
- Sponsor
- Siirt Training and Research Hospital
Intertransverse Process Block, Subcostal Transverse Abdominis Plane Block
Intertransverse Process Block Versus Subcostal Transversus Abdominis Plane Block After Laparoscopic Sleeve Gastrectomy
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITPB) and the Subcostal Transversus Abdominis Plane Block (TAPB) in patients undergoing laparoscopic sleeve…
- Conditions
- Intertransverse Process Block, Subcostal Transverse Abdominis Plane Block, Sleeve Gastrectomy, Postoperative Pain
- Trial name
- NCT07591129
- Testing
- Intertransverse Process Block, The Subcostal Transversus Abdominis Plane Block (TAPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Post Operative Pain Control, PONV
Effectiveness of Unilateral Transversus Abdominis Plane (TAP) Block vs Bilateral TAP Block in Patients Undergoing Laparoscopic Cholecystectomy.
In this study, patients undergoing laparoscopic cholecystectomy will be randomly divided into 2 groups after consent. Group A patients will be administered a one-sided (right unilateral) regional TAP block and group B patients…
- Trial name
- NCT07513012
- Testing
- Unilateral Transversus abdominis plane (TAP) block with 0.25 % bupivacaine, Bilateral Transversus abdominis plane (TAP) block with 0.25 % bupivacaine
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- King Edward Medical University
Gastroesophageal Adenocarcinoma
Paclitaxel, Ramucirumab and Tislelizumab Switch Maintenance in Advanced HER2-negative and PD-L1 TAP Score of 5 or More Advanced Gastroesophageal Adenocarcinoma
ARMANI-2/ENGIC8 is a randomized, open-label, phase III trial evaluating a switch maintenance strategy in patients with previously untreated, locally advanced unresectable or metastatic, HER2-negative and PD-L1-positive…
- Trial name
- ARMANI-2 (NCT07763171)
- Testing
- FOLFOX (5-fluorouracil, Leucovorin, Oxaliplatin), CAPOX (oxaliplatin/capecitabine), CDDP, 5 Fu
- Where
- 42 sites in Germany, Italy and 1 more
- Volunteers
- 244 people
- Sponsor
- Gruppo Oncologico del Nord-Ovest
Postoperative Pain, Acute
Comparison of Transversus Abdominis Plane and Erector Spinae Plane Blocks for Pain Control After Renal Laparoscopy
The goal of this study is to compare the analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block versus erector spinae plane block (ESPB) in adult patients undergoing laparoscopic renal surgeries.
- Trial name
- TAP-ESPB (NCT07781930)
- Testing
- TAP Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Inguinal Hernia, Postoperative Pain
Lumbar ESP Block Versus TAP Block for Postoperative Pain Control in Children Undergoing Open Inguinal Hernia Repair
This study evaluates two ultrasound-guided nerve block techniques-Erector Spinae Plane Block (ESPB) and Transversus Abdominis Plane (TAP) block-for pain relief in children undergoing elective open inguinal hernia repair.
- Trial name
- NCT07916233
- Testing
- Ultrasound-guided Lumbar Erector Spinae Plane Block (ESPB), Ultrasound-guided Transversus Abdominis Plane (TAP) Block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Beni-Suef University
Analgesia
Neostigmine as an Adjuvant in Tranversus Abdominis Plane (TAP) Block in Cesarean Section Under Spinal Anesthesia
Cesarean birth is a common surgical procedure. After cesarean birth, postsurgical pain may delay recovery, interfere with maternal-newborn bonding, and reduce the breastfeeding if not adequately controlled.
- Trial name
- TAB (NCT05785377)
- Testing
- Bupivacaine-Neostigmine, Bupivacaine
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Mansoura University
Bowel Disease
Bilateral TAP and RS Blocks Using Liposomal Bupivacaine/Bupivacaine vs. Regular Bupivacaine in Laparoscopic Colectomy
This study will be a single center, prospective triple blinded randomized controlled study, comparing the use of liposomal bupivacaine (Exparel) to regular bupivacaine with adjuncts in bilateral mid-abdominal transverse abdominis…
- Trial name
- TAPLIP (NCT05224089)
- Testing
- Liposomal Bupivicaine/Bupivacaine Admixture, Bupivacaine HCL
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Hartford Hospital
Procedural Pain, Vaccination Pain
Cold Spray and Helfer Skin Tap for Pain During Infant Vaccination
This randomized controlled experimental study aims to evaluate the effects of cold spray and the Helfer Skin Tap technique on pain levels during intramuscular pneumococcal conjugate vaccine administration in 12-month-old infants.
- Conditions
- Procedural Pain, Vaccination Pain, Injection Pain
- Trial name
- NCT07779681
- Testing
- Cold spray, Helfer Skin Tap Technique
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hitit University
Pregnancy, Cesarean Section
Intrathecal MoRphine Versus Transabdominal Plane Block (TAP) Block for AnalGesic Management in Elective Caesarean Section
The goal of this randomized controlled clinical trial is to determine if low-dose intrathecal morphine is superior to a Transversus Abdominis Plane (TAP) block with ropivacaine and clonidine for postoperative analgesia in women…
- Conditions
- Pregnancy, Cesarean Section, Neuroaxial Analgesia Procedures
- Trial name
- MIRAGE (NCT07377630)
- Testing
- Intrathecal Morphine, TAP Block
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Giannina Gaslini
Idiopathic Normal Pressure Hydrocephalus
Integrated Multimodal Assessment to Optimize Diagnosis and Surgical Selection in Idiopathic Normal Pressure Hydrocephalus
Idiopathic normal pressure hydrocephalus (iNPH) is a neurological condition that can cause walking difficulties, cognitive impairment, and urinary incontinence.
- Trial name
- NPH-OPTIMIZE (NCT07427836)
- Where
- 2 sites in Italy
- Volunteers
- 116 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico