Clinical trials: Partial Paralysis
Stroke, Gait, Hemiplegic
A Comparison Between the Exoskeleton Hybrid Assistive Limb and Conventional Gait Training Early After Stroke
Overall aim is to evaluate HAL for gait training early after stroke and the effect of HAL on short- and long-term functioning, disability and health compared to conventional gait training as part of an inpatient rehabilitation…
- Conditions
- Stroke, Gait, Hemiplegic, Ambulation Difficulty, Hemiparesis
- Trial name
- HAL-RCT (NCT02410915)
- Testing
- Hybrid Assistive Limb (HAL); gait training, Control Group; Conventional gait training
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Danderyd Hospital
Stroke, Acute, Stroke, Ischemic
Effects of Atalante Exoskeleton on Gait Recovery in Non- or Poorly Ambulatory Patients With Hemiparesis in the Acute/Subacute Phase (Month 1 to 4)
The present clinical investigation - EarlyExo, is an interventional, international, multicentric, prospective, single-blinded randomized controlled trial.
- Conditions
- Stroke, Acute, Stroke, Ischemic, Stroke, Subacute, Stroke Hemorrhagic
- Trial name
- EarlyExo (NCT06107010)
- Testing
- Use of the Atalante exoskeleton
- Where
- 5 sites in France, Germany and 1 more
- Volunteers
- 66 people
- Sponsor
- Wandercraft
Meniscectomy
Muscle Weakness and Post-traumatic Knee OA
This is a single-center, randomized, single-blind (evaluator) study. Enrolled patients had a traumatic meniscal tear and underwent meniscectomy.
- Trial name
- NCT01879852
- Testing
- Quadriceps intensive strengthening, Standard rehabilitation
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Florida
Stroke, Hemiparesis
Locomotor Training for Neurological Disease
The purpose of this study is to determine whether split belt training can be used to treat walking pattern deficits from stroke and to determine whether different schedules and types of long term training on a custom split belt…
- Trial name
- NCT01288040
- Testing
- Split Belt treadmill
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Septic Shock, Adverse Event
Early Versus Conventional Cessation of Hydrocortisone in Septic Shock
Septic shock is one of the causes of death in ICU and hospital. Refractory shock is the problem which healthcare providers should recognize though it is difficult to handle with.
- Conditions
- Septic Shock, Adverse Event, Hydrocortisone, Hyperglycemia
- Trial name
- CESSHYDRO (NCT05818826)
- Testing
- normal saline solution, Hydrocortisone and normal saline solution
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Mahidol University
Stroke
Effect of Upper Extremity Rehabilitation Using Immersive Virtual Reality in Chronic Stroke Patients.
The study aimed to investigate the effect of exergames using virtual reality with head mounted device on motor recovery of upper extremities in chronic stroke patients.
- Trial name
- NCT05148052
- Testing
- Virtual reality exergames, Conventional occupational therapy
- Where
- 3 sites in South Korea
- Volunteers
- 15 people
- Sponsor
- Seoul National University Hospital
Emphysema or COPD
Improve Muscle Weakness in Patient With COPD
This randomized controlled trial investigated the effects of combining aerobic exercise with blood flow restriction (BFR) training in patients with emphysematous chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT07649850
- Testing
- Aerobic Exercise Combined with Blood Flow Restriction, Aerobic exercise
- Sponsor
- Al-Zaytoonah University of Jordan
Spasticity/Paresis, Cerebral Palsy
Efficacy of Extracorporeal Shock Wave Therapy in Children With Cerebral Palsy
Spastic plantar and palmar flexion deformities are very common in children with cerebral palsy (CP). These deformities usually involve spasticity of the plantar or palmar muscle complexes, weakness of the antagonist dorsiflexor…
- Trial name
- NCT06128616
- Testing
- ESWT, Botulinum Toxin Type A, Serial Casting
- Volunteers
- 40 people
- Sponsor
- Kocaeli University
Muscular Weakness
Training Intrinsic Foot Muscles
The foot intrinsic muscles are increasingly targeted in foot and ankle rehabilitation. The exercises are often difficult to learn initially.
- Trial name
- NCT03670563
- Testing
- Short foot exercise protocol, Short foot exercise plus NMES
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Muscle Weakness
Evaluation of Muscle Strength by Transcutaneous Electrical Stimulation
Acquired Neuromyopathy of Resuscitation (NMAR) is a common condition. Its diagnosis is difficult and often late because it is based on a clinical assessment of muscle strength (MRC score) requiring the patient to be awake and…
- Trial name
- STRENGTH-ICU (NCT03270163)
- Testing
- Transcutaneous electrical stimulation, Magnetic stimulation, ultrasound measurement
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Sensorimotor Gait Disorder, Neurologic Ambulation Disorder
Clinical Study of the L300 Versus Ankle-foot Orthosis (AFO) on Post-Stroke Subjects With Foot Drop
The objective of this study is to determine the effectiveness of the NESS L300 (L300) in improving gait parameters, function, and quality of life among stroke subjects (greater than or equal to 3 months post stroke)with drop foot.
- Conditions
- Sensorimotor Gait Disorder, Neurologic Ambulation Disorder, Gait, Drop Foot, Poststroke Hemiparesis
- Trial name
- L300 (NCT01138995)
- Testing
- Ness L300, Ankle-foot orthosis
- Where
- 11 sites in United States
- Volunteers
- 197 people
- Sponsor
- Bioness Inc
Facial Paresis
Using the Deep Temporal Nerves Versus the Masseteric Nerve for Correction of Eyelid Paresis.
The return of eyelid function and facial expression in Patients with facial nerve affection is very important for quality of life.
- Trial name
- NCT04543318
- Testing
- Deep temporal nerves, massteric nerve
- Volunteers
- 24 people
- Sponsor
- Assiut University
Intensive Care Unit, Respiratory Insufficiency
Low Creatinine Level and Respiratory Failure
Low creatinine levels may be a sign of muscle atrophy or weakness, and therefore predictive for respiratory insufficiency in the Intensive care unit (ICU) patients.
- Conditions
- Intensive Care Unit, Respiratory Insufficiency, Muscle Weakness
- Trial name
- NCT04368325
- Testing
- Serum creatinine levels
- Where
- Croatia
- Volunteers
- 107 people
- Sponsor
- Osijek University Hospital
Stroke, Ischemic, Stroke Hemorrhagic
Exploring Accessible Beauty for Individuals With Upper Extremity Deficits
The purpose of this study is to investigate the accessibility of beauty products for individuals with upper extremity disabilities.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke (CVA) or TIA, Stroke, Acute
- Trial name
- NCT05945784
- Testing
- Use of Rare Beauty makeup products
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Muscle Weakness Condition, Hand Grasp
Effect of Texting and Writing on Grip and Pinch Strength
Texting and writing are common hand activities among college students. Students tend to spend increasing hours of texting and writing for every day activities in addition to the academic assignments that are mainly on line and…
- Trial name
- NCT04810416
- Testing
- Texting- 10 minutes, Writing- 10 minutes, Texting- 15 minutes
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Stroke, Upper Extremity Paresis
Effects of Bihemispheric Transcranial Direct Current Stimulation on Motor Function in Stroke Patients
Motor impairment (impairment of movement) due to stroke is one of the leading disabilities in adults. In addition to established means of facilitating motor recovery after stroke such as physical and occupational therapy, a…
- Conditions
- Stroke, Upper Extremity Paresis, Transcranial Direct Current Stimulation
- Trial name
- NCT03839316
- Testing
- tDCS
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Baskent University
Muscle Weakness, Weaning Failure
Abdominal Muscle Thickness in Mechanically Ventilated Patients
The purpose of the study is to determine to what extent the abdominal muscles contribute to airway pressure, in order to investigate the correlation between muscles weakness and extubation outcome in mechanically ventilated…
- Trial name
- NCT03567564
- Testing
- Abdominal muscles ultrasound
- Where
- 2 sites in Canada, Italy
- Volunteers
- 35 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Stroke, Hemiparesis
CONSTRAINT-INDUCED MOVEMENT THERAPY (CIMT) VS. MIRROR THERAPY (MT) ON HAND FUNCTION AND SPASTICITY IN PATIENTS WITH HEMIPARESIS
This study aimed to compare the effects of Constraint-Induced Movement Therapy (CIMT) and Mirror Therapy (MT) on hand function and spasticity in individuals with hemiparesis.
- Conditions
- Stroke, Hemiparesis, Hemiparesis After Stroke
- Trial name
- NCT06910904
- Testing
- Constraint-Induced Movement Therapy (CIMT), Mirror Therapy (MT)
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- University of Lahore
Hamstring Injury, Muscle Tone Increased
Cranial Laser Reflex Technique for Hamstring Function
Purpose: To conduct a pilot study of the effect of Cranial Laser Reflex Technique (CLRT) compared with sham laser on hamstring muscle flexibility, strength, and pain pressure threshold.
- Conditions
- Hamstring Injury, Muscle Tone Increased, Muscle Pain, Muscle Weakness
- Trial name
- CLRTHam (NCT03044106)
- Testing
- CLRT
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Stroke Ischemic
Paired Associative Stimulation (PAS) for Stroke Rehabilitation
Paired associative stimulation (PAS) delivered with multi-channel deep transcranial magnetic stimulation (dTMS) may enhance motor recovery in patients with first-ever ischemic stroke.
- Trial name
- PAS-Stroke (NCT07691099)
- Testing
- A multi-channel device with deep TMS coil (Brainsway Ltd., Jerusalem, Israel)
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Soroka University Medical Center
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