Clinical trials: Parturition
Child Maltreatment
Evaluation of a 2-session Parent Training Programme for Caregivers of Younger Children in Zimbabwe
A pilot, exploratory cluster Randomised Controlled Trial (RCT) with two arms will be conducted to test a two-session parent training programme for caregivers of children enrolled in early childhood development classes in Harare…
- Trial name
- NCT06431321
- Testing
- Tabudira Parenting Intervention for Early Childhood Development, Nutritional guide for younger children
- Where
- Zimbabwe
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Urinary Tract Infections, Cesarean Section; Infection
Caesarean Delivery With or Without an Indwelling Bladder Catheter
The aim of this study is to compare the incidence of catheter associated culture-based urinary tract infection (UTI) after elective CD with or without preoperative placement of a urinary catheter.
- Trial name
- NCT03672214
- Testing
- Without placement of indwelling catheter, With placement of indwelling catheter
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Labor Pain
Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management During Labor.
This is a randomized, double-blind, crossover clinical trial to evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) as a non-pharmacological therapeutic intervention for reducing pain in women during the…
- Trial name
- TENS-LABOR (NCT07401147)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS); TENSCARE Perfect Mama+ TENS unit
- Where
- 2 sites in Honduras
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Ricardo A Gutierrez Ramirez, MD, MSc, FACOG
Perineal Pain, Birth Satisfaction
The Effect of Birth Ball and Perineal Massage on Perineal Pain, Perineal Trauma and Birth Satisfaction
One of the important causes of perineal trauma is perineal tension. By reducing this tension, perineal trauma can be prevented. Perineal trauma is a birth complication that can be prevented with midwifery approaches.
- Conditions
- Perineal Pain, Birth Satisfaction, Perineal Laceration, Tear, or Rupture During Delivery
- Trial name
- NCT06935643
- Testing
- Birth Ball, Perineal Massage, Control Group
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pregnancy, Ovarian
The Number of Blastocysts Formed in the Outcome of Freeze All Strategy: COMFFETI Trial, Cumulative Delivery Rate
A prospective study of the blastulation rate in the outcome of the Freeze all strategy
- Trial name
- NCT03463278
- Testing
- Pregnancy Rate
- Where
- Greece
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assisting Nature
Labor Pain, Pregnancy
Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
The purpose of this study in nulliparous women undergoing induction of labor is to determine whether initiation of neuraxial analgesia compared to systemic opioid analgesia early in labor (< 4 cm cervical dilation)affects the…
- Trial name
- NCT00380978
- Testing
- combined spinal epidural analgesia, late analgesia (systemic)
- Where
- United States
- Volunteers
- 1,026 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Infant, Extremely Premature, Length of Stay
Trial of Patterned Oral Somatosensory Entrainment for Shortening Time to Oral Feeding
The primary hypothesis is that the preterm infants (26 0/7 to 30 6/7 weeks gestational age) who undergo the NTrainer System® training will transition to full oral feeds faster than the control group (i.e.
- Conditions
- Infant, Extremely Premature, Length of Stay, Feeding
- Trial name
- NCT01158391
- Testing
- NTrainer® Intervention, Control Intervention
- Where
- 5 sites in United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- KC BioMediX, Inc
Pregnancy
Measuring Preferences for Childbirth After Cesarean
The objective of this proposed 18-month exploratory research study is to help pregnant women weigh risks and benefits in a childbirth decision using the Preferences-Assessment Computer Module.
- Trial name
- NCT00267735
- Testing
- Use of Computerized Decision Aid on Childbirth
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Fear of Childbirth Pregnancy Childbirth Education Birth Preferences
Effect of Theory-Based Childbirth Preparation Education in Nulliparous Pregnant Women
This randomized controlled trial aims to evaluate the effect of a Health Belief Model- and Self-Efficacy Theory-based childbirth preparation education on fear of childbirth, childbirth self-efficacy, birth preferences, and…
- Trial name
- HBM-SE Birth (NCT07692724)
- Testing
- Health Belief Model and Self-Efficacy Theory-Based Childbirth Preparation Education, Routine Antenatal Care
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sibel Akgül Kartal
Healthy Volunteers
A Randomised, Cross-over, Relative Bioavailability Study of Nicotine Delivery and Nicotine Extraction From Oral Products
This study is a randomised cross-over, open-label, confinement study conducted in 24 male or female snus and cigarette consumers. The study investigates 5 different nicotine containing products in a cross-over fashion.
- Trial name
- NCT04891406
- Testing
- A, B, C
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Imperial Brands PLC
Stress Disorders, Post-Traumatic, Depressive Disorder, Major
The Effect of Traumatic Childbirth on the Incidence of PTSD and Other Major Postpartum Psychopathology
Determination of incidence and prevalence of PTSD and other types of psychopathology (such as anxiety and affective disorders) after traumatic birth experiences and elucidation of salient risk factors in the local population…
- Trial name
- NCT02370576
- Testing
- rating scale application
- Where
- Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Anxiety
An Informative Video About Perineal Tears During Labor for Anxiety Reduction: A Randomized Controlled Trial
This study evaluates the impact of an informative video about perineal tears on maternal anxiety during labor. Perineal trauma during childbirth, especially severe tears such as obstetric anal sphincter injuries (OASIS), is…
- Trial name
- VITAL (NCT07064213)
- Testing
- Behavioral: Educational Video
- Where
- Israel
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Induction of Labor
Castor Oil Ingestion and Balloon Catheter for Labor Induction in Multiparous
The goal of this randomized controlled trial is to examine the efficacy of combining castor oil ingestion with extra-amniotic single balloon catheter for cervical ripening on time from induction to delivery in multiparous women.
- Trial name
- NCT06335017
- Testing
- Induction of labor
- Where
- Israel
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Nazareth, Israel
Parturient Who Underwent Epidural Anesthesia During Which an Unintentional Dural Punctur Occurred, Parturient Who Develop a Postdural Puncture Headache
Chronic Headache and Chronic Backache Following Unintentional Dural Puncture at Delivery Room.
he study is a telephone questionnaire. The study will include 400 women, 100 in each group. OBJECTIVE: To investigate the prevalence of chronic and chronic back pain following PDPH accidental dural puncture during epidyral…
- Conditions
- Parturient Who Underwent Epidural Anesthesia During Which an Unintentional Dural Punctur Occurred, Parturient Who Develop a Postdural Puncture Headache, Parturient Who Gave Informed Consent to Participation in the Study
- Trial name
- NCT03908424
- Testing
- Epidural Blood patch.
- Where
- Israel
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Microstomia, Scleroderma
Hyaluronidase Via LADD Scleroderma-induced Microstomia
Two treatment methods, ablative carbon dioxide (CO2) laser and intradermal hyaluronidase, will be combined to maximize the beneficial potential of each.
- Trial name
- NCT05995626
- Testing
- Hyaluronidase, CO2 laser
- Where
- 2 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Premature, Behavior, Child
Effects of Oriental Music on Preterm Infants
The goal of this study is to explore the effect of oriental music on premature infants' physiological and behavioral parameters during their hospital stay in the NICU.
- Trial name
- NCT04565210
- Testing
- Music exposure, Silence
- Where
- Lebanon
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Healthy Adult Participants
A Study to Assess the Bioavailability and Adhesion of Selegiline TDS in Healthy Subjects
The purpose of this research study is to compare the bioavailability and adhesion of a generic Selegiline transdermal system (TDS) against the marketed comparator (EMSAM®) in healthy volunteers.
- Trial name
- NCT07571824
- Testing
- Selegiline TDS 6 mg/24 hours, EMSAM® TDS 6 mg/24 hours
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Corium Innovations, Inc.
Premature Birth, Newborn
Pain Management in Neonatal Intensive Care Units by Studying the Autonomic Balance
Fight against the pain caused by the disease or by the diagnostic and therapeutic procedures is a daily and essential concern for the caregiver neonatologist.
- Trial name
- NIPE-DOL (NCT02764424)
- Testing
- NIPE (MDoloris®)
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Post Operative Pain
The Safety and Efficacy of Surgical Rectus Sheath Block for Postoperative Analgesia After Elective Cesarean Delivery
All participants will receive spinal anaesthesia and will be randomly divided into 2 equal groups. In Group 1, 20 ml of local anesthetic solution will be administered bilaterally to the rectus sheath space under direct vision…
- Trial name
- NCT06020196
- Testing
- surgical rectus sheath block, subdermal local anaesthetic infiltration
- Where
- Egypt
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Ahmed M Maged, MD
Diphtheria, Hepatitis B
Safety Study of a Vaccine Against Meningitis in Infants ( 2,4 & 6 Months Age) After a Birth Dose of Hepatitis B.
The purpose of this study is to compare the reactogenicity \& safety of Tritanrix™-HepB/Hib-MenAC vaccine to the international standard of care, Tritanrix™-HepB/Hiberix™.
- Conditions
- Diphtheria, Hepatitis B, Whole Cell Pertussis, Haemophilus Influenzae Type b
- Trial name
- NCT00317135
- Testing
- Tritanrix-HepB/Meningitec conjugate vaccine, Tritanrix/Hiberix vaccine
- Where
- Philippines
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
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