Clinical trials: Patients With Pathological ECG
Tachyarrhythmia
APART: Prevention and Automatic Therapy of Atrial Arrhythmias in Patients With Paroxysmal Supraventricular Tachycardias
The goal of APART is the assessment of the therapeutic and preventive stimulation algorithms of the Medtronic AT500 and following devices in patients with atrial tachyarrhythmias and an indication for cardiac pacing according to…
- Trial name
- NCT00170274
- Testing
- Activation of preventive and therapeutic algorithms for treatment of AF, AF Prevention and Therapy Algorithms On
- Where
- 6 sites in Germany
- Volunteers
- 156 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Ekg Change Ischemia Lateral
Diagnostic Value of Electrocardiographic St-t Wave Changes in Patients With Chronic Stable Angina
The electrocardiogram (ECG) is a simple and non-invasive bedside diagnostic tool with a well-established role in the diagnosis of (CAD).
- Trial name
- ECG (NCT02027506)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Alexandria University
Hyperkalaemia
AI-Enabled ECG Stratification and Timing of Potassium-Lowering Therapy in Patients With Hyperkalemia: A Target Trial Emulation Study
Hyperkalemia is a common and potentially life-threatening electrolyte disorder, yet there is limited evidence guiding the optimal timing of potassium-lowering therapy in routine clinical practice.
- Trial name
- AIDE-K (NCT07307729)
- Testing
- Timely treatment, Delayed treatment
- Volunteers
- 5,000 people
- Sponsor
- National Defense Medical Center, Taiwan
Tetralogy of Fallot (TOF), Ventricular Tachycardia
Validation of ECG-Based Ventricular Arrhythmia Localization Algorithms in Patients With Repaired Tetralogy of Fallot
Doctors use patterns on heart rhythm tracings (ECGs) to predict where abnormal heart rhythms originate, but these prediction methods were developed in people with normal heart structure.
- Trial name
- NCT07607821
- Testing
- RV and LV pace mapping
- Volunteers
- 30 people
- Sponsor
- Boston Children's Hospital
ST Elevation Myocardial Infarction
Study of Efficacy and Safety of GNR-060 vs Metalyse in Patients With ST Elevation Myocardial Infarction
GNR-060(JSC "GENERIUM", Russia) is a proposed biosimilar to the referent product Metalyse. This study is to compare the clinical efficacy and safety of GNR-060 vs Metalyse as a thrombolitic agent in patients with with ST…
- Trial name
- NCT05601999
- Testing
- GNR-060, Metalyse
- Where
- 11 sites in Russia
- Volunteers
- 244 people
- Sponsor
- AO GENERIUM
Bradycardia, Heart Failure
ECG Belt to Assess Electrical Synchronization
The objective of the study is to assess the utility of ECG Belt to understand the conduction and ECG characteristics of Left Bundle Branch Pacing (LBBAP) and His-Optimized Cardiac Resynchronization Therapy (HOT-CRT) and compare…
- Trial name
- NCT04583709
- Testing
- ECG Belt
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Pugazhendhi Vijayaraman
Myocardial Infarction
Pre-Hospital Wireless Transmission of Electrocardiograms to a Cardiologist Via a Hand-Held Device
Aim: To determine the impact of wireless transmission of prehospital ECGs to a hand-held computer on time to treatment and myocardial salvage in acute MI patients.
- Trial name
- NCT00682526
- Testing
- SmartLink Wireless Monitoring System (K033642)
- Where
- 7 sites in United States
- Volunteers
- 527 people
- Sponsor
- Welch Allyn
Acute Coronary Syndrome
Assessment of Biomarkers for Diagnosis in Geriatric Patients
Elderly patients are often admitted to hospital because of chest pain that is atypical for angina pectoris. In case of inconclusive electrocardiograms, determination of troponin is important for the diagnosis of an acute coronary…
- Trial name
- BOSCH1 (NCT01370395)
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Cardiotoxicity
Cardiotoxicity Monitoring With Single-lead Electrocardiogram
This research is a multi-center prospective cohort interventional study aimed to determinate the capabilities of remote 1-minute single-lead electrocardiogram monitoring for cardiotoxicity detection, during two- three weeks…
- Trial name
- NCT05676606
- Testing
- Remote 1-minute single-lead electrocardiogram (ECG) monitoring in cancer patients after the first polychemotherapy cycle.
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Atrial Fibrillation
Atrial Fibrillation Monitoring on Patients With Lymphoma After Chemotherapy
This prospective cohort study is to investigate the incidence of atrial fibrillation after chemotherapy by aplying wearable ECG recoder and the risk factors on patients with newly diagonsed lymphoma
- Trial name
- NCT05454878
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
NSTEMI - Non-ST Segment Elevation MI
TIII Over TI in Subjects With Myocardial Infarction
Study was performed to identify ECG criteria for unmasking of subjects with NSTEMI at elevated risk.
- Trial name
- T-infarction (NCT03057093)
- Testing
- Non interventional study
- Volunteers
- 903 people
- Sponsor
- University of Cologne
Acute Coronary Syndrome, Chest Pain
Are Serial Electrocardiograms Additive to SeriAl Second-generations Troponins in Predicting Acute CoronAry Syndromes in PatienTs With Undifferentiated cHest Pain
Our research will examine whether the presence or absence of serial electrocardiogram (ECG) changes aids in reclassifying participants' risk for major adverse cardiac events (MACE) over and above serial blood testing.
- Trial name
- ASAP Cath (NCT01953276)
- Testing
- Serial Electrocardiograms
- Where
- United States
- Volunteers
- 382 people
- Sponsor
- Wake Forest University Health Sciences
Atrial Fibrillation
A Prospective, Multi-center, Randomized Clinical Trial to Evaluate the Detection of Atrial Fibrillation Using Artificial Intelligence-Enhanced Electrocardiography (SmartECG-AFrisk) Compared With Usual Care in Patients With Suspected Atrial Fibrillation: DEEP-AF
"The DEEP-AF study is a prospective, multi-center, randomized clinical trial evaluating the effectiveness of an artificial intelligence-enhanced electrocardiography algorithm (SmartECG-AFrisk) for early detection of atrial…
- Trial name
- NCT07173673
- Testing
- Usual Care (General Practice), AI-ECG Guided Care (SmartECG-AFrisk)
- Where
- South Korea
- Volunteers
- 1,230 people
- Sponsor
- Yonsei University
Atrial Fibrillation
The Use of Flecainide for Treatment of Atrial Fibrillation
This prospective observational study will include patients with atrial fibrillation that has indication for treatement with flecainide. Included patients are followed during a 12 month period.
- Trial name
- NCT05084495
- Testing
- Global peak atrial longitudinal strain and ECG
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Lund University
Atrial Fibrillation
Observational Study of Sinus Rhythm Mapping in Pulmonary Vein Isolation Naive Patients With Atrial Fibrillation
Atrial fibrillation (AF) initially starts in a paroxysmal form, which is mainly based on the presence of triggers. Progression of AF is accompanied by structural and electrical remodelling which can typically be described as a…
- Trial name
- SUSTAINER (NCT06098664)
- Testing
- AI-enabled ECG score for Atrial Fibrillation (DNN score), Atrial voltage map in sinus rhythm
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Ziekenhuis Oost-Limburg
Heart Failure, Left Bundle-Branch Block
HIS Alternative II - UK Site
The study will investigate the feasibility of using direct HIS pacing or left bundle branch pacing (LBB pacing) as an alternative to biventricular pacing in patients with symptomatic heart failure and an ECG with a typical left…
- Trial name
- NCT05814263
- Testing
- HIS/LBB pacing, LV pacing
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Imperial College Healthcare NHS Trust
Atrial Fibrillation
Validation Study of Frontier X Plus (FX+) Device
The main objective of this study is to validate the specificity and sensitivity of FX+ detecting atrial fibrillation (AF) in both AF and non-AF subjects using a comparative approach, which involves using both a US FDA-cleared…
- Trial name
- NCT06471764
- Testing
- FX+ and 12-Lead ECG Recording
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Fourth Frontier Technologies Pvt Ltd.
Atrial Fibrillation
Clinical Investigation to Determine the Accuracy and Benefit of Cardioskin™ in Patients With Known Atrial Fibrillation
This is a prospective, non-randomized, comparative, single-arm, open label, multi- centre, post-market clinical investigation involving an expected 74 subjects (minimum 40, maximum 118) suffering from paroxysmal AF with the aim…
- Trial name
- NCT03964025
- Testing
- Wearing Cardioskin™ for 14 days
- Where
- 3 sites in Netherlands
- Sponsor
- Institut de Recherches Internationales Servier
Myocardial Infarction (MI)
Efficacy and Safety Study of Proposed Biosimilar Product Reveliza vs Actilise in Patients With ST-segment Elevation Myocardial Infarction
Thi is is a multi-center, randomized, single-blind, parallel group clinical trial to evaluate the efficacy and safety of the intravenious thrombolysis with Revelise® (GENERIUM, Russia) in comparosin with the Actilyse® (Boehringer…
- Trial name
- NCT07146360
- Testing
- Revelise (GENERIUM, Russia), Actilyse® (Boehringer Ingelheim Pharma GmbH and Co.KG, Germany)
- Where
- 22 sites in Russia
- Volunteers
- 180 people
- Sponsor
- AO GENERIUM
Atrial Fibrillation (AF), Cardiac Amyloidosis
Early Detection of Concealed Cardiac Amyloidosis Using AI-ECG and CT-Derived Extracellular Volume in Patients With Atrial Fibrillation
This study investigates the clinical efficacy of a non-invasive screening protocol using AI-ECG and CT-ECV analysis for cardiac amyloidosis. The study targets on atrial fibrillation(AF) patients with "red-flag" indicators.
- Trial name
- SEARCH-AF (NCT07567508)
- Testing
- AI-ECG analysis, CT-ECV analysis, Atrial fibrillation treatment
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Samsung Medical Center