Clinical trials: Perception of Pain
Sciatic Nerve, Lower Extremity Pain
Effect of Sciatic Nerve Mobilization on Lower Extremity Pain Perception
This randomized controlled study aims to investigate the effect of sciatic nerve mobilization on pain perception in lower extremity peripheral nerves, specifically the tibial and common peroneal nerves.
- Trial name
- NCT07525895
- Testing
- Sciatic Nerve Mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Dental Fear and Anxiety
Assessing the Efficacy of Lemongrass and Lavender Aromatherapy in Reducing Dental Anxiety and Pain Associated With Local Anesthetic Injections in Pediatric Dental Patients
The goal of this clinical trial is to evaluate whether aromatherapy using lemongrass or lavender essential oils can reduce dental anxiety and pain perception in children aged 7-11 years undergoing local anesthetic administration…
- Trial name
- NCT07113080
- Testing
- lavender essential oil inhaled using face mask, lemongrass essential oil inhaled using face mask
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hiba Ahmed Eltayeb
Pain Perception in Endodontic Treatment, Menstrual Cycle
Menstrual Cycle, Menopause, and Pain Perception During Endodontic Treatment
The goal of this observational study is to investigate whether menstrual cycle phases and menopausal status are associated with pain perception in patients undergoing endodontic treatment.
- Conditions
- Pain Perception in Endodontic Treatment, Menstrual Cycle, Menopause
- Trial name
- NCT07850167
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Virtual Reality, Vaccination
Virtual Reality for the Treatment of Pain in Pediatric Vaccination
Objective: to estimate the effect of virtual reality as a distracting technique against traditional distracting techniques in the vaccination procedure in the pediatric population. Design: randomized clinical trial.
- Conditions
- Virtual Reality, Vaccination, Pain, Nursing
- Trial name
- NCT04096833
- Testing
- Virtual Reality Group
- Where
- Spain
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Anxiety, Hormone, Labour, Pain, Midwife, Pregnant, Transcutaneous Electrical Nerve Stimulation
Evaluation of the Effect of Transcutaneous Electrical Nerve Stimulation During Delivery
Pain and anxiety levels experienced during labour are important factors affecting mother and baby health. An indicator that affects these factors is the levels of hormones that special for birth in the mother's blood.
- Trial name
- NCT04851938
- Testing
- transcutaneous electrical nerve stimulation device
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Pain Perception
The Effect of Transcutaneous Magnetic Stimulation on Acute Pain.
This is a single institution, single-blinded, long-term exploratory study using participant as his/her own control to evaluate and compare the potential analgesic effect on experimental heat pain of Transcutaneous Magnetic…
- Trial name
- NCT03777137
- Testing
- TMS (Rapid2, Magstim Corp)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Motor Activity
Investigating Motor Cortex Processing for Pain Modulation
The purpose of this study is to investigate the effects of different types of interventions (motor learning, somatosensory learning, observation task, mental imagery and tDCS) on the perception of pain and motor cortex…
- Trial name
- NCT01404039
- Testing
- Motor Learning, Somatosensory Learning, Observational Task
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Breast Neoplasms, Survivorship
PI-targeted PNE+MI Compared to BIOMEDICAL Education in BCS
Breast cancer is the most frequently diagnosed cancer in women worldwide. An important portion of the breast cancer survivors will face chronic pain complaints.
- Conditions
- Breast Neoplasms, Survivorship, Pain, Chronic
- Trial name
- BCS-PI (NCT04730154)
- Testing
- Pain Neuroscience Education (PNE), Motivational Interviewing (MI), Biomedically-focused education
- Where
- 4 sites in Belgium
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Dental Phobia, Dental Anxiety
Assessment of Pain, Anxiety and Efficiency of NumBee Compared to Traditional Local Anesthetic Syringe
The study was conducted among a group of dental patients aged (6-8 years old) of both genders to assess the following variables in the needleless interparliamentary anesthesia (NUMBEE) compared to traditional local anesthesia: 1.
- Conditions
- Dental Phobia, Dental Anxiety, Anesthesia, Local, Needle Phobia
- Trial name
- NCT05899296
- Testing
- dental syringe ( NumBee), Traditional dental syringe
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Duaa Kamal Naji
Shoulder Pain, Healthy Volunteers
Sensory Processing and Musculoskeletal Shoulder Pain
The development of chronic pain is a common complication in shoulder pain conditions. Half of these type of patients exhibit persistent pain even after a period of six to twelve months from the start of their pain treatment.
- Trial name
- NCT05368649
- Testing
- Short-wave diathermy
- Where
- Argentina
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Gran Rosario
Orthodontic Appliance Complication
Assessment of Coated Orthodontic Miniscrews With Chlorhexidine Hexametaphosphate Antimicrobial Nanoparticles
Aim To compare between orthodontic miniscrews coated and uncoated with CHX- HMP NP nanoparticles.
- Trial name
- NCT06124235
- Testing
- Coated Orthodontic Miniscrews with Chlorhexidine Hexametaphosphate Nanoparticles, Uncoated Miniscrew with Chlorhexidine Hexametaphosphate Nanoparticles
- Where
- Iraq
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Pain Sensation, Hyperalgesia
Pain Response to Cannabidiol in Induced Acute Nociceptive Pain, Allodynia and Hyperalgesia By Using a Model Mimicking Acute Pain in Healthy Adults
This study is to investigate the effect of CBD on acute pain in healthy volunteers in a well-established acute pain model.
- Conditions
- Pain Sensation, Hyperalgesia, Allodynia
- Trial name
- CANAB I (NCT03985995)
- Testing
- CBD 800 mg p.o
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Episiotomy Wound, Wound Healing
Episiotomy Wound Care, Episiotomy Wound Healing and Pain Perception
The World Health Organization (WHO) and professional societies recommend restricted episiotomy instead of routine episiotomy. However, since the 1990s, there has been evidence of the risks of the procedure, and although routine…
- Conditions
- Episiotomy Wound, Wound Healing, Pain, Training, Toilet
- Trial name
- NCT05358236
- Testing
- Episiotomy Wound Care and Genital Hygiene Training
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Anterior Teeth Alignment Efficiency, Pain Perception
Comparison of Conventional and Cu-NiTi Archwires Regarding Clinical Efficiency and Pain Intensity Using Prostaglandin E2 Biomarker During Alignment and Leveling
Orthodontic treatment can inflame the periodontium and dental pulp, it can be uncomfortable and even painful at times. This may induce discomfort and the release of different biochemical mediators, which is one of the main causes…
- Conditions
- Anterior Teeth Alignment Efficiency, Pain Perception, PGE2 Biomarker and Their Correlation
- Trial name
- NCT06653881
- Testing
- ARCHWIRE
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Healthy
Objective Markers of Pain Perception in Humans
Determine objective markers of pain perception remains a major scientific and medical issue. Various tools have been proposed to objectify pain, but their adaptability to different clinical contexts are limited.
- Trial name
- NCT02559999
- Testing
- Painful tonic stimuli, non-painful stimuli
- Where
- 2 sites in France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Anxiety, Pain
Effect of Augmented Reality on Dental Anxiety and Pain Perception in Children
The aim of this study is to reduce dental anxiety in children by using augmented reality (AG) with a special content and innovative interactive methods, to determine the level of stress experienced by patients during dental…
- Trial name
- NCT06530654
- Testing
- Distraction by dentist, Distraction by cartoon movie, AG-active distraction group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Local Anesthetic Infiltration, Topical Anesthesia
Topical Cryoanesthesia Versus Benzocaine in Pediatric Dentistry
This clinical study tested and compared two ways (cold-base technique or "cryoanesthesia" and conventional benzocaine gel) to reduce pain from dental injections in children.
- Conditions
- Local Anesthetic Infiltration, Topical Anesthesia, Pain Perception
- Trial name
- No acronym (NCT07351383)
- Testing
- Local Anesthesia (lidocaine hydrochloride)
- Where
- Mexico
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Pain, Breast Pain
e-Nature VR: Evaluation of the Impact of Virtual Reality During Breast Biopsy
Randomized clinical trial about the evaluation of the impact of the virtual reality intervention on the experience of pain, physical and psychological discomfort, well-being and anxiety of women during breast biopsy use of nature…
- Trial name
- e-Nature VR (NCT03877094)
- Testing
- Nature virtual reality video
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Orthodontic Pain (D013850), Malocclusion
Comparison of Three Orthodontic Separators for Pain, Plaque, and Tooth Separation
Orthodontic separators are small devices placed between teeth before fitting braces to create space for bands. This procedure may cause pain, discomfort, and changes in oral hygiene, which can affect plaque buildup and daily…
- Conditions
- Orthodontic Pain (D013850), Malocclusion, Orthodontic Treatment
- Trial name
- SEP-ORTHO (NCT07532044)
- Testing
- Elastomeric Separator, Kesling Separator, Tie wire separator
- Where
- Pakistan
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Islamabad Medical and Dental College
Root Canal Treatment
Post-Endodontic Pain According to Menstrual Cycle Phases
This study aimed to evaluate whether the phase of the menstrual cycle affects pain after root canal treatment. A total of 99 patients (72 females and 27 males) who needed root canal treatment in lower molar teeth were included.
- Trial name
- PEP-MC (NCT07291518)
- Testing
- root canal treathment
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Ahter Sanal Cikman