Clinical trials: Percutaneous Nephrolithotomy (PCNL)
Kidney Stone
Effects of Abdominal Cushion on PCNL in Prone Position
Percutaneous nephrolithotomy (PCNL) is the first choice for the treatment of ≥ 2cm renal stones. The positions of PCNL includes supine, prone and lateral. PCNL has been performed in my center for nearly twenty years.
- Trial name
- NCT03797027
- Testing
- Percutaneous Nephrolithotomy without an abdominal cushion, Percutaneous Nephrolithotomy with an 5 cm abdominal cushion
- Where
- China
- Volunteers
- 180 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Stone
Reducing Opioid Prescription After Kidney Stone Removal Surgery
The purpose of this study is to implement and assess a standard way of prescribing opioid pain medication following PCNL (a kidney stone removal surgery) to ensure patients are being discharged with an appropriate quantity of…
- Trial name
- NCT05353478
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
Kidney Stones
Flexible Ureteroscopy With a Flexible and Navigable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy for 1-2 cm Lower Pole Kidney Stones
This study, known as the FLAME Trial (Flexible ureteroscopy for Lower pole stones And Mini-pErcutaneous nephrolithotomy), is an international, multicenter, randomized, non-inferiority trial.
- Trial name
- FLAME (NCT07159035)
- Testing
- Flexible ureteroscopy with FANS, Mini-percutaneous nephrolithotomy (mini-PCNL)
- Where
- China
- Volunteers
- 640 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Renal Calculi
A Pilot Study Assessing The Feasibility Of Outpatient Tubeless Percutaneous Nephrolithotomy (PCNL)
Outpatient tubeless Percutaneous nephrolithotomy (PCNL) could potentially improve patient care and result in significant cost savings for our hospital each year.
- Trial name
- NCT01437904
- Testing
- Outpatient Recovery, In hospital recovery
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Queen's University
Postoperative Pain, Nephrolithiasis
A Randomized, Double-Blind, Placebo-Controlled Trial of Anrikefon for Postoperative Analgesia After Percutaneous Nephrolithotomy
This study evaluates whether a single dose of anrikefon, given intravenously shortly before the end of kidney stone removal surgery (PCNL), can reduce opioid-related side effects such as nausea, vomiting, itching, oversedation…
- Trial name
- ARK-PCNL (NCT07825142)
- Testing
- Anrikefon
- Volunteers
- 160 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Renal Stone, Percutaneous
Erector Spinae Versus Paravertebral in Pediatric PCNL
To compare the efficacy of ultrasound-guided erector spinae plane block versus ultrasound-guided paravertebral block in pediatric patients undergoing percutaneous nephrolithotomy
- Conditions
- Renal Stone, Percutaneous, Nephrolithotomy
- Trial name
- NCT05589649
- Testing
- Erector spinae plane block, Paravertebral block
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Assiut University
Kidney Stone
Robotic-assisted Percutaneous Access
This is a first-in-man (FIM) study to show feasibility and safety profile of the newly developed robotic device for percutaneous access in PCNL surgery.
- Trial name
- NCT04435132
- Testing
- PCL under fluoroscopy with the aid of the robotic device
- Where
- Malaysia
- Volunteers
- 5 people
- Sponsor
- NDR Medical Technology Pte Ltd
Percutaneous Nephrolithotomy (PCNL), Postoperative Pain
The Effect of NSAID Steroid Therapy for PGE2 Level and Analgesia After Percutaneous Nephrolithotomy Surgery
The goal of this clinical trial is to learn if combination of NSAID-steroid can decrease the PGE2 level and postoperative pain after percutaneous nephrolithotomy surgery.
- Trial name
- BUPARDEX (NCT06604598)
- Testing
- IBU-PCT-DEX
- Where
- Indonesia
- Volunteers
- 45 people
- Sponsor
- Universitas Jenderal Soedirman
Percutaneous Nephrolithotomy (PCNL), Nephrolithiasis
Erector Spinae Plane Block for Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is an effective standard urological procedure for the fragmentation and removal of large renal calculi.
- Conditions
- Percutaneous Nephrolithotomy (PCNL), Nephrolithiasis, Renal Calculi
- Trial name
- NCT07457983
- Testing
- Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fadime Tosun
Artery Pseudoaneurysm After PCNL
Renal Artery Pseudoaneurysm After PCNL
In a multicenter retrospective study, to assess the incidence and risk factors of renal artery pseudoaneurysm after percutaneous nephrolithotomy, and to characterize the clinical presentation and treatment outcomes.
- Trial name
- NCT07724912
- Testing
- Embolization of a renal artery branch pseudoaneurysm
- Volunteers
- 50 people
- Sponsor
- Botkin Hospital
Nephrolithiasis
RIRS With Flex Suction Sheath vs. PCNL for 2-3 cm Renal Stones
This is a multicenter, randomized controlled trial comparing retrograde intrarenal surgery (RIRS) using a tip-flexible suction access sheath with standard percutaneous nephrolithotomy (PCNL) for the treatment of 2-3 cm unilateral…
- Trial name
- NCT07058402
- Testing
- Retrograde Intrarenal Surgery (RIRS) with Tip-Flexible Suction Access Sheath, Standard Percutaneous Nephrolithotomy (PCNL)
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Changhai Hospital
Anesthesia Techniques, Percutaneous Nephrolithotomy
Effects of Spinal vs General Anesthesia on Systemic Inflammation in PCNL
This observational study aims to compare the effects of spinal and general anesthesia on perioperative systemic inflammatory response in patients undergoing percutaneous nephrolithotomy (PCNL).
- Conditions
- Anesthesia Techniques, Percutaneous Nephrolithotomy, Systemic Inflammation
- Trial name
- PCNL-ANES-INF (NCT07326670)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Renal Stones
Postoperative Outcomes of PCNL vs RIRS in Obese Patients With Pelvic 1.5:3 cm Renal Stones
This prospective randomized comparative study was done at Helwan University Hospital. It was conducted on 120 patients with unilateral pelvic renal stones from 1.5 to 3 cm in largest diameter who was admitted through duration to…
- Trial name
- PCNL VS RIRS (NCT06175910)
- Testing
- percutaneous nephrolithotomy, retrograde intrarenal surgery
- Where
- Egypt
- Volunteers
- 182 people
- Sponsor
- bassem metwally
Urolithiasis, Kidney Stone
Flexible Ureteroscopy With Tip-bendable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy for Treatment of 2-3cm Renal Stones
Background: Percutaneous nephrolithotomy (PCNL) is the first-line treatment for renal stones larger than 2 cm according to EAU and AUA guidelines.
- Trial name
- NCT06526390
- Testing
- f-URS, mini-PCNL
- Where
- China
- Volunteers
- 720 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Stone
A RCT to Evaluate the Efficacy and Safety of Automated Needle Targeting (ANT-X) System Compared to Traditional Free Hand Puncture for Renal Access in Percutaneous Nephrolithotomy (PCNL)
Objectives: This study aims to determine if the device provides an advantage over traditional free hand puncture by comparing the number of attempts required to obtain access, time to achieve access, radiation exposure to patient…
- Trial name
- NCT05213702
- Testing
- Renal Calyx punture with traditional free hand or ANT-X device
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Percutaneous Nephrolithotomy
Lower Thoracic Epidural vs Erector Spinae Block for PNL
compare the efficacy of Lower Thoracic Epidural with Erector spinae plane block (ESPB) for post-operative analgesia after Percutaneous Nephrolithotomy with a hypothesis that both Lower Thoracic Epidural and Erector spinae plane…
- Trial name
- NCT05725083
- Testing
- Lower thoracic epidural, Erector spinae plane block
- Volunteers
- 42 people
- Sponsor
- Assiut University
Urolithiasis
Comparing Previously Placed Nephrostomy Tract (NT) Versus Single Stage Percutaneous Nephrolithotomy (PCNL)
The investigators are trying to determine whether placement of a nephrostomy tube prior to definitive stone surgery and under ultrasonic or fluoroscopic guidance will reduce complications related to bleeding and infection compare…
- Trial name
- NCT00907946
- Testing
- NT 1 day before PCNL
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Washington University School of Medicine
Postoperative Pain, Kidney Calculi
Nephrostomy Tract Infiltration for Pain Control After PCNL
This prospective, randomized, controlled clinical trial aims to evaluate the effectiveness of nephrostomy tract local anesthetic infiltration for postoperative pain control in patients undergoing prone percutaneous…
- Trial name
- NCT07721571
- Testing
- Bupivacaine, Intravenous Tramadol and Paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hitit University
Kidney Stone
A Prospective Observational Comparison of SMP and ESWL for the Treatment of Renal Stones ≥20 mm in Children (IAU-04)
ESWL and PNL are the two treatment modalities for kidney stones greater than 20 mm in the pediatric population. ESWL is non-invasive, does not require anesthesia and inexpensive, but its success rate may be lower, and require…
- Trial name
- NCT04317443
- Testing
- Super-mini percutaneous nephrolithotomy (SMP), Extracorporeal Shock Wave Lithotripsy (ESWL)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The International Alliance of Urolithiasis
Renal Stone
ROBOTIC PYELOLITHIOTOMY VERSUS PERCUTANEOUS NEPHROLITHOTOMY (PCNL).
Prospectively randomized study in patients with renal pelvic stones who are candidate to standard PCNL procedure. One to one, controlled clinical trial.
- Trial name
- NCT03046888
- Testing
- Robot assisted pyelolithotomy
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Zealand University Hospital