Clinical trials: Percutaneous Transluminal Angioplasty
Angioplasty, Transluminal, Percutaneous Coronary
Study of Tirofiban Administration in Patients With Aspirin and or Clopidogrel Resistance
This study will evaluate whether adding tirofiban, administered at high bolus dose on top of aspirin and clopidogrel will lead to a lower rate of periprocedural myocardial infarction after percutaneous coronary intervention in…
- Trial name
- 3T/2R (NCT00398463)
- Testing
- Tirofiban
- Where
- Italy
- Volunteers
- 263 people
- Sponsor
- Università degli Studi di Ferrara
Renal Artery Obstruction, Hypertension, Renal
The HERCULES Trial - A Safety and Effectiveness Study of the Herculink Elite Renal Stent to Treat Renal Artery Stenosis
The purpose of this study is to determine whether the Herculink Elite Renal Stent System is safe and effective in the treatment of renal artery stenosis in patients with less than optimal angioplasty results and uncontrolled…
- Trial name
- HERCULES (NCT00490841)
- Testing
- Herculink Elite Renal Stent System
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Abbott Medical Devices
Coronary Artery Disease, Arterial Occlusive Diseases
IRIS-Onyx Cohort in the IRIS-DES Registry
The purpose of this study is to evaluate the relative effectiveness and safety of Onyx stent compared to other (drug eluting stents) DES.
- Conditions
- Coronary Artery Disease, Arterial Occlusive Diseases, Cardiovascular Diseases, Percutaneous Transluminal Angioplasty
- Trial name
- IRIS-Onyx (NCT02593994)
- Testing
- Onyx Drug Eluting Stent group
- Where
- 31 sites in South Korea
- Volunteers
- 4,500 people
- Sponsor
- Seung-Jung Park
Percutaneous Transluminal Angioplasty, Wound Heal
Measurement of Revascularization Effect Using NIRS in BTK Arteries
Patient with occluded below the knee arteries and chronic limb ischemia Rutherford class V-VI are enrolled. During endovascular recanalisation procedure changes in tissue oxygen amount is recorded using near infrared spectroscopy…
- Conditions
- Percutaneous Transluminal Angioplasty, Wound Heal, Ischemic Feet
- Trial name
- NCT03898869
- Testing
- Intraoperative NIRS monitoring
- Where
- Lithuania
- Volunteers
- 30 people
- Sponsor
- Vilnius University
Atherosclerosis, Chronic Kidney Disease
Revascularization of Renal Artery Stenosis Versus Medical Therapy for the Treatment of Ischemic Nephropathy
The aim of the study is to value, in patients with chronic kidney disease and hypertension, whether medical therapy plus interventional renal artery revascularization is superior to medical therapy alone for the treatment of…
- Conditions
- Atherosclerosis, Chronic Kidney Disease, Hypertension, Renovascular, Ischemic Nephropathy
- Trial name
- NITER (NCT01023373)
- Testing
- Medical treatment, PTRS, renal artery stent
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Azienda Unita Sanitaria Locale di Piacenza
Angioplasty, Percutaneous Coronary Intervention
Palpitate-Eluting Balloon Angioplasty in the Treatment of Coronary Bifurcation Lesion Evaluated by OCT
The aim of the study is to use optical coherence tomography (OCT) to investigate the efficacy of Paclitaxel-eluting PTCA-balloon dilation (SeQuent Please) in SB and drug eluting stent (EXCEL stent) deployment in the main branch…
- Trial name
- PEBCBLO (NCT02276846)
- Testing
- Paclitaxel-Eluting Balloon
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Hospital of Jilin University
Coronary Artery Ischemia
Remote Myocardial Ischemic Preconditioning in Humans
Ischemic preconditioning (IP) has been shown in animal studies to increase the myocardial tolerance to subsequent ischemia. Our primary hypothesis is that remote IP reduces myocardial ischemic injury during PCI.
- Trial name
- RemoteMIPH (NCT00588042)
- Testing
- Blood pressure cuff
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Mayo Clinic
Peripheral Artery Disease
Effects of Prolonged DAPT After Lower Extremity Percutaneous Transluminal Angioplasty (PTA) in Patients With LE-PAD
The objective of the present study was to evaluate the prognostic impact of prolonged dual antiplatelet therapy (DAPT) with acetylsalicylic acid plus clopidogrel on the incidence of major adverse cardiovascular events and major…
- Trial name
- LONGDAPTPAD (NCT02798913)
- Testing
- Short DAPT, Long DAPT
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Federico II University
Angina Pectoris, Unstable Angina
Pilot Study of Hemoglobin Based Oxygen Therapeutics in Elective Coronary Revascularization
The purpose of this study is to assess the safety and feasibility of a novel oxygen carrying solution, HBOC-201, in the setting of PCI for Acute Coronary Syndromes from randomization til hospital discharge.
- Conditions
- Angina Pectoris, Unstable Angina, Myocardial Infarction
- Trial name
- NCT00317512
- Testing
- Percutaneous Coronary Revascularization, Hemoglobin-Based Oxygen Carrier-201 (HBOC-201), Voluven
- Where
- 6 sites in Belgium, Germany and 1 more
- Volunteers
- 45 people
- Sponsor
- Biopure Corporation
Atherosclerotic Narrowing of the Superficial Femoral Artery, Atherosclerotic Occlusion of the Superficial Femoral Artery
The Safety and Efficacy of Photodynamic Therapy for Femoral Artery Stenosis
Rstenosis is common after angioplasty of atherosclerotic disease of the femoral artery. Pilot study data suggests that adjuvant photodynamic therapy, using delta amino kleavulinic acid as a photosensitiserr is feasible and safe.
- Trial name
- NCT00187811
- Testing
- Delta amino leavulinic acid photodynamic therapy
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University College London Hospitals
Femoropopliteal Artery Lesions
Ranger™ and Ranger™ SL (OTW) DCB) in China
This clinical study is a prospective, non-randomized, multicenter study to demonstrate the acceptable safety and performance of angioplasty with the Ranger DCB in native femoropopliteal artery lesions.
- Trial name
- NCT02944071
- Testing
- Boston Scientific Ranger™ and Ranger™ SL Paclitaxel-Coated PTA Balloon Catheter
- Where
- 9 sites in China
- Volunteers
- 123 people
- Sponsor
- Boston Scientific Corporation
Cardiovascular Disease, Coronary Artery Disease
Italian Registry on Unprotected Left Main
The RITMO (Registro Italiano sul trattamento del Tronco coMune non protettO) observational study will appraise the prevalence, management strategy, and prognosis of unprotected left main coronary artery disease in Italy.
- Trial name
- RITMO (NCT00612053)
- Where
- Italy
- Volunteers
- 1,200 people
- Sponsor
- University of Turin, Italy
Angina, Unstable, Angioplasty, Transluminal, Percutaneous Coronary
A Study Evaluating the Efficacy and Safety of Abciximab, an Anti-platelet Therapy, in Patients Undergoing High-risk Coronary Angioplasty
The purpose of this study is to evaluate the effectiveness and safety of abciximab (an anti-platelet therapy) versus placebo in patients undergoing high risk coronary angioplasty.
- Trial name
- NCT00269893
- Testing
- Abciximab
- Volunteers
- 2,038 people
- Sponsor
- Centocor, Inc.
PTA (Percutaneous Transluminal Angioplasty), Femoropopliteal Artery Disease
One-Year Results of GENOSS PCB Real-World Study in Femoropopliteal Artery Disease
The purpose of this study is to evaluate the long-term safety and efficacy of GENOSS PCB by enrolling and tracking patients who underwent percutaneous transluminal angioplasty using GENOSS PCB in patients with femoropopliteal…
- Trial name
- NCT07431437
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Genoss Co., Ltd.
Coronary Artery Disease
Evaluation of Coronary Luminal Diameter Enlargement With Emerge™ 1.20 mm PTCA Dilatation Catheter
To evaluate the acute safety and device procedural success of the Emerge 1.20 mm PTCA dilatation catheter when used as a pre-dilatation device in the stenotic portion of coronary arteries or bypass grafts.
- Trial name
- NCT01635881
- Testing
- Emerge™ 1.20 mm PTCA Dilatation Catheter
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston Scientific Corporation
Femoral Artery Stenosis, Popliteal Artery Stenosis
IN.PACT Admiral Drug-Coated Balloon vs. Standard Balloon Angioplasty for the Treatment of Superficial Femoral Artery (SFA) and Proximal Popliteal Artery (PPA)
The purpose of the study is to demonstrate the safety and efficacy of the IN.PACT Admiral drug-coated balloon (DCB) in comparison to any standard balloon for treatment of peripheral arterial disease (PAD) in the superficial…
- Conditions
- Femoral Artery Stenosis, Popliteal Artery Stenosis, Femoral Artery Occlusion, Popliteal Artery Occlusion
- Trial name
- INPACT SFA II (NCT01566461)
- Testing
- Drug-Coated Balloon (DCB), PTA Balloon: Balloon Angioplasty
- Where
- 2 sites in United States
- Volunteers
- 331 people
- Sponsor
- Medtronic Endovascular
Acute Myocardial Infarction
The Effects of Facilitated Percutaeous Coronary Intervention in Acute Myocardial Infarction
The purpose of this study to investigate whether the administration of high-dose tirofiban before primary PCI could reduce myocardial infarct size, using analysis of contrast-enhanced magnetic resonance imaging.
- Trial name
- NCT00611169
- Testing
- tirofiban
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Femoral Artery Stenosis, Popliteal Artery Stenosis
MDT-2113 Drug-Eluting Balloon vs. Standard PTA for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery and/or Proximal Popliteal Artery
The purpose of this trial is to assess the safety and efficacy of MDT-2113 for the interventional treatment of de novo and non-stented restenotic lesions in the superficial femoral artery (SFA) and the proximal popliteal artery…
- Conditions
- Femoral Artery Stenosis, Popliteal Artery Stenosis, Femoral Artery Occlusion, Popliteal Artery Occlusion
- Trial name
- MDT-2113 SFA (NCT01947478)
- Testing
- MDT-2113 Drug-Eluting Balloon, Standard angioplasty balloon
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Medtronic Endovascular
Myocardial Infarction
Efficacy of Early Administration of Clotinab in Acute Myocardial Infarction
The ADMIRAL (Platelet glycoprotein IIb/IIIa inhibition with coronary stenting for acute myocardial infarction) study demonstrated that early administration of abciximab in patients with ST elevation acute myocardial infarction…
- Trial name
- ECLAT-STEMI (NCT00841438)
- Testing
- Clotinab
- Where
- 31 sites in South Korea
- Volunteers
- 786 people
- Sponsor
- Yonsei University
Arteriovenous Graft Thrombosis, End Stage Renal Disease on Dialysis
Changes in Regional Ventilation-Perfusion Match Following Percutaneous Transluminal Angioplasty for Arteriovenous Graft Thrombosis
Patients with end-stage renal disease (ESRD) often require arteriovenous grafts (AVG) for hemodialysis. AVG thrombosis is a common complication, usually managed by percutaneous transluminal angioplasty (PTA) to restore blood…
- Trial name
- NCT07613632
- Testing
- Electrical Impedance Tomography (EIT) Monitoring
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College