Clinical trials: Peri-implant Bone and Soft Tissues
Bone Loss, Inflammation
Healing of Bone/Soft Tissue to Different Abutment Biomaterials and the Impact on Marginal Bone Loss
In patients that require a dental implant, does zirconia compared to titanium, or cad-cam acrylic abutments, provide less inflammation, marginal bone loss or infection during the osseointegration period ?
- Trial name
- NCT01961635
- Testing
- dental implants, Zirconia abutments, Titanium Abutments
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Tooth Loss
Clinical Assessment of Dental Implant
Primary Endpoints : The implant survival and success rate of V3 and C1 implants will be compared. Implant success rate will be evaluated by measuring the peri-implant bone remodeling from baseline to 1 year post insertion.
- Trial name
- H2015-1 (NCT02591706)
- Testing
- MIS Implants
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Liege
Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption
Peri-Implant Hard and Soft Tissue Changes After Immediate Implant Placement With Socket Shield and Immediate Restoration Versus Early Implant Placement in the Esthetic Zone
This randomized controlled clinical trial aims to compare peri-implant hard and soft tissue dimensional changes following immediate implant placement with the socket shield technique and immediate restoration versus early type II…
- Conditions
- Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption, Partial Edentulism of the Maxilla
- Trial name
- NCT07468760
- Testing
- Socket Shield, Early Implant Placement
- Where
- United Arab Emirates
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Dental Implant, Prosthetic Abutment
One-time Abutment Placement Versus 4 Times Abutment Removal Around Dental Implants
Introduction: the repeated connection and disconnection of healing abutments during dental implants´ osseointegration has been associated with significant increased peri-implant bone loss, when compared with placing the final…
- Trial name
- NCT05711147
- Testing
- Abutment removal, Placement of definitive abutment
- Where
- Spain
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Peri-implant Tissue Response With Use of Customized Healing Abutments
Effect of Customized Healing Abutments on Peri-implant Soft Tissue and Bone
The goal of this clinical trial is to evaluate effect of customized healing abutment in patients who need single implant reconstruction.
- Trial name
- NCT06125418
- Testing
- customized healing abutment, standard healing abutment
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Peri-Implantitis, Soft Tissue
Association of Keratinised Mucosa Around Implants and Teeth With Peri-implant/Periodontal Disease and Soft Tissue Conditioning
Lack of keratinised mucosa around dental implants and teeth is associated with plaque accumulation and worse tissue conditions. However, there is lack of data on the influence of the presence/lack of keratinised mucosa on the…
- Conditions
- Peri-Implantitis, Soft Tissue, Bone Gain
- Trial name
- NCT03501537
- Testing
- Free gingival graft obtained from the palate and debridement of the peri-implant lesion
- Where
- Spain
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Alveolar Bone Loss
Soft Tissue Width and Abutment Height Influence Peri-implant Bone Resorption
The purpose of this clinical and radiographic study will be to determine what influence on marginal bone loss has the thickness of soft tissues and the height of the prosthetic abutment and eventually determine which of the two…
- Trial name
- i-RES (NCT03229005)
- Testing
- implant insertion, operculectomy, prosthetic rehabilitation
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Alveolar Ridge Augmentation, Bone Transplantation
Peri-Implant Soft and Hard Tissue Stability Following Socket Preservation
The viability of Platelet Rich Fibrin (PRF) on enhancement of osseous and associated tissue healing has been substantiated well in literature.
- Trial name
- NCT05005377
- Testing
- Socket Preservation with Platelet-Rich Fibrin, Socket Preservation with Freeze-Dried Bone Allograft
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Dental Implant-Abutment Designs, Marginal Bone Loss in Different Abutment Designs
Peri-implant Tissues Changes for Different Abutment Shapes and Heights
The goal of this randomized clinical trial is to investigate the influence of supracrestal soft tissue on abutments of different heights (2-mm vs. 3-mm) and shapes (cylindrical abutment vs.
- Conditions
- Dental Implant-Abutment Designs, Marginal Bone Loss in Different Abutment Designs, Soft Tissue Management in Subcrestal Dental Implants
- Trial name
- NCT07509281
- Testing
- Bone-Level Implant Placement with Transmucosal Abutment and One Abutment-One Time Protocol
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Complete Edentulism
PeriImplant Soft Tissue and Marginal Bone Loss of Single Implant Mandibular Overdenture
There is a significant difference between CM LOC and ball attachment, when considering the peri-implant soft tissue health and marginal bone loss.
- Trial name
- NCT02881905
- Testing
- ball attachment, cm loc attachment
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Soft Tissue Healing
Peri-implant Soft Tissue and Bone Evaluation in Fully Computer Guided Immediate Implants
Prospective evaluation of perimplant soft tissue and bone response to one abutment one-time concept versus provisional abutment in fully guided single immediate implant placement.
- Trial name
- randomised (NCT06733870)
- Testing
- guided immediate implant surgery
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Peri-Implant Health, Peri-Implant Tissues
Comparison Between Free Gingival Graft and Palatal Pedicle Flap
Patients requiring KMW gain(mm) during uncovering surgery were included. Two surgical methods were compared: apically position flap with free gingival graft (FGG group) and the palatal pedicle flap with collagen matrix (PPF…
- Conditions
- Peri-Implant Health, Peri-Implant Tissues, Peri-implant Bone Level
- Trial name
- Pedicle (NCT06816680)
- Testing
- APF + FGG, PPF group
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Compressive Implants
Immediate Loading of Four Single Piece Compressive Implants for Bar Retained Mandibular Overdenture
this study was done to evaluate clinically and radiographically four single piece inter-foraminal compressive implant connected via digitally designed co-cr milled bar with distal cantilever supporting mandibular overdenture.
- Trial name
- NCT06514391
- Testing
- compressive single piece dental implant
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mansoura University
One-Piece Dental Implant, Bone-Level Implant
Inflammatory Biomarkers, Microbial Findings, and Clinical Characteristics Before and After Treatment of Peri-Implant Mucositis Around One-Piece and Two-Piece Dental Implants
The goal of this clinical study was to learn whether the design of a dental implant affects how the gums around it respond to treatment of peri-implant mucositis, an early and reversible inflammation of the soft tissue around a…
- Conditions
- One-Piece Dental Implant, Bone-Level Implant, Two-Piece Dental Implant, Nonsurgical Mechanical Debridement
- Trial name
- 1PvsBL (NCT07892313)
- Testing
- Nonsurgical Mechanical Debridement With 1% Chlorhexidine Gel
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cuneyt Asim Aral
Soft Tissues According to the Abutment Torque, Microleakage Accordint to the Abutment Torque
Impact of Abutment Screw Torque on Marginal Bone Loss
The objective of this clinical trial is to evaluate the impact of different torque values applied during transmucosal abutment placement in dental implants on marginal bone loss and peri-implant parameters, including the…
- Conditions
- Soft Tissues According to the Abutment Torque, Microleakage Accordint to the Abutment Torque, PROMS According to the Abutment Torque, Marginal Bone Loss According to the Abutment Torque
- Trial name
- NCT07234552
- Testing
- Abutment torqued to 15 Ncm, Pilar torqued to 30 Ncm, 2 mm healing cap
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Soft Tissue Augmentation
Acellular Dermal Matrix Versus Tenting Technique in Peri-implant Soft Tissue Augmentation and Crestal Bone Stability
This study looks at two ways to make gums thicker and bones stable around dental implants for people with thin gums. It compares two methods in 40 people: one method uses a special graft, and the other uses a technique called…
- Trial name
- NCT06302387
- Testing
- Acellular Dermal Matrix, Soft Tissue Expansion using Tenting Technique
- Where
- Lithuania
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Dental Implant, Soft Tissue
Effect of Bone-related and Soft-tissue-related Variables on the Marginal Bone Loss of Platform-matched and Platform Switched Dental Implants
In this clinical trial the effect of the implant-abutment morphology (platform-switched vs platform matched) will be assessed in both soft tissue (soft tissue thickness) and hard tissue (marginal bone loss) outcomes.
- Conditions
- Dental Implant, Soft Tissue, Partial-edentulism, Bone Loss
- Trial name
- NCT05670340
- Testing
- Switched Prosthetic Profile, Matched Prosthetic Profile
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Evaluating the Clinical Efficacy of Applying Ultraviolet Photofunctionalization (UV phF) to Standard Titanium Implants Immediately Before Surgery, Monitoring Early Implant Stability and Osseointegration During the Critical Initial Healing Phase
Clinical Assessment of UV Photofunctionalization on Stability and Osseointegration of Early Loaded Implants
The goal of this clinical trial is to learn if UV light treatment (photo functionalization) works to help dental implants heal faster and become stable enough for early use in adults missing teeth in the lower back jaw.
- Conditions
- Evaluating the Clinical Efficacy of Applying Ultraviolet Photofunctionalization (UV phF) to Standard Titanium Implants Immediately Before Surgery, Monitoring Early Implant Stability and Osseointegration During the Critical Initial Healing Phase, Determining the Feasibility and Success Rate of an Accelerated "Early Loading" Protocol, Assessing the Survival Rate of the Implants, Along With the Peri-implant Soft Tissue Response and Marginal Bone Preservation
- Trial name
- UV (NCT07868744)
- Testing
- UV-photofunctionalized titanium dental implants
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Bone Resorption, Soft Tissue Bleeding
Influence of Neck Design on Peri-implant Hard and Soft Tissues
The goal of this clinical trial is to test two different implant neck designs in 36 patients. The main question[s] it aims to answer are: do triangular neck designed implants placed immediately after dental extraction have the…
- Trial name
- NCT05944419
- Testing
- Immediate implant surgery
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Dental Implant Placement, Soft Tissue Management in Subcrestal Dental Implants
Implant Placement Depth and Peri-Implant Tissue Outcomes
The primary aim of this randomized clinical trial is to evaluate the influence of subcrestal implant placement depth (-2 mm vs -4 mm) on peri-implant marginal bone level changes, including marginal bone loss and bone remodeling.
- Conditions
- Dental Implant Placement, Soft Tissue Management in Subcrestal Dental Implants, Marginal Bone Loss
- Trial name
- NCT07535528
- Testing
- Subcrestal Implant Placement with Transmucosal Abutment and One Abutment-One Time Protocol
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Valencia