Clinical trials: Perineural
Intra and Postoperative Pain Management
The Analgesic Efficacy of Perineural Nalbuphine as an Adjuvant to Bupivacaine in Ultrasound Guided Superficial Cervical Plexus Nerve Block for Thyroid Surgeries. A Double Blinded Randomized Controlled Trial.
This study aiming to evaluate the analgesic effect of adding nalbuphine as an adjuvant to bupivacaine in superficial cervical plexus block during thyroid surgeries regarding first rescue analgesia in the first twenty-four hours…
- Trial name
- NCT06633068
- Testing
- Adding perineural Nalbuphine to Bupivacaine in superficial cervical nerve block
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Carpal Tunnel Syndrome
Vitamin B12 for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT03802422
- Testing
- Vitamin B12, Normal saline
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Regional Anesthesia, Sciatic Nerve Block
Comparing Through-the-Needle With Suture-Method Catheter Designs for Popliteal Nerve Blocks
Following painful surgical procedures, postoperative analgesia is often provided with a single-injection peripheral nerve block.
- Trial name
- NCT03442036
- Testing
- Suture-Method Technique, Through-the-Needle Technique
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Continuous Femoral Nerve Blocks in Healthy Volunteers
Effects of Catheter Tip Location Relative to the Femoral Nerve on Sensory and Motor Function
To determine if the way local anesthetic, or numbing medication, is delivered through a tiny tube next to the nerves that go to the thigh affects the strength and sensation in the thigh.
- Trial name
- NCT01263249
- Testing
- Catheter Anterior to the Femoral Nerve, Catheter Posterior to the Femoral Nerve
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Anesthesia, Anesthesia, Local
A Study in Healthy Male Volunteers to Investigate the Safety and Tolerability of a Single Dose of Neosaxitoxin Alone and in Combination With Bupivacaine (With and Without Epinephrine) for Brachial Plexus Blockade
Neosaxitoxin is a new compound that is in clinical development as local anesthetic for surgical anesthesia and postoperative analgesia.
- Conditions
- Anesthesia, Anesthesia, Local, Analgesia
- Trial name
- NCT03399435
- Testing
- Neosaxitoxin combined with bupivacaine low and epinephrine (T1), Bupivacaine low combined with epinephrine (C1), Bupivacaine high combined with epinephrine (C2)
- Where
- Netherlands
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Carpal Tunnel Syndrome
Different Sessions of Perineural Injection With Dextrose for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT03802435
- Testing
- two-sessions of ultrasound-guided PIT, One-sessions of ultrasound-guided PIT
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Ulnar Neuropathy at Elbow
Platelet-rich Plasma Injection for Ulnar Neuropathy at Elbow
Ulnar neuropathy at elbow (UNE) is the second common peripheral entrapment neuropathy after carpal tunnel syndrome (CTS). Although many conservative managements of UNE were found, their effectiveness were often unsatisfied…
- Trial name
- NCT04264000
- Testing
- platelet-rich plasma, 5% dextrose
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yung-Tsan Wu
Impacted Third Molar Tooth
Perineural and Systemic Dexamethasone Use in Dental Surgeries in Terms of Anesthesia Duration and Postop Complaints
Participants will be asked to use some medications after the tooth extraction procedure. These drugs can be used in different ways.
- Trial name
- NCT06318013
- Testing
- vitality test
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Catheter Infection
Local Inflammation Does Not Correlate With Bacterial Colonization and Contamination of Perineural Catheters
The aim of this study was to investigate the influence of alcoholic skin disin-fection before PNC (perineural catheter)-removal on the detection of bacteria on the subcutaneous part of the PNC or on the tip.
- Trial name
- NCT02599181
- Testing
- propanol-biphenol: Kodan
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Ulnar Neuropathy at Elbow
Efficacy of Ultrasound-Guided PRP Versus Corticosteroid Injection in Patients With Ulnar Neuropathy at Elbow
This study was be performed on 60 patients with ulnar neuropathy at elbow diagnosed clinically and by electrophysiology and/or ultrasonography selected from Physical medicine, Rheumatology \& Rehabilitation Department, Faculty of…
- Trial name
- NCT05567081
- Testing
- Triamcinolone Acetonide 40mg/mL, PRP
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
Perineural, Methylene Blue
Perineural Methylene Blue Infusion in Lower Limb Amputation Surgery
This prospective randomized controlled study will be conducted to evaluate the analgesic effect of continuous perineural infusion of methylene blue with bupivacaine on acute postoperative pain and to evaluate its preventive role…
- Conditions
- Perineural, Methylene Blue, Lower Limb Amputation
- Trial name
- NCT05830630
- Testing
- Bupivacaine methylene blue, bupivacaine saline
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Tanta University
Nerve Block
Continuous Infraclavicular Nerve Blocks: Needle Versus Catheter Local Anesthetic Bolus
The investigators propose to test the hypothesis that when placing a perineural catheter for a continuous peripheral nerve block, injecting the initial local anesthetic bolus via the insertion needle results in a faster-onset…
- Trial name
- NCT01377545
- Testing
- Local Anesthetic given via perineural catheter for infraclavicular nerve block., Local Anesthetic given via needle for infraclavicular nerve block
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego
Tourniquet Hypertension, Intraoperative Hypertension
Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter Reverses Tourniquet Associated Ischemic Hypertension
The goal of this prospective randomized double-blind study is to determine if an ultrasound guided peri-arterial injection of local anesthetic (LA) superomedially the femoral artery via peripheral nerve catheter reverses ischemic…
- Conditions
- Tourniquet Hypertension, Intraoperative Hypertension, Total Ankle Arthroplasty, Ankle Fusion
- Trial name
- NCT04454203
- Testing
- Mepivacaine, Saline, Perifemoral Injection of Local Anesthetic
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Healthy
Does Perineural Clonidine Prolong Duration of a Nerve Block?
The aim of this trial is to investigate if clonidine prolongs the duration of an adductor canal block. By using healthy volunteers the investigators can perform a bilateral adductor canal block and thereby control for a systemic…
- Trial name
- NCT02444559
- Testing
- Ropivacaine 20ml 5mg/ml+ Clonidine 150ug
- Where
- Denmark
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Carpal Tunnel Syndrome
Radiofrequency, Perineural Injection, Idiopathic Carpal Tunnel Syndrome
Aim of the study The aim of the study is to evaluate the role of pulsed radiofrequency versus platelet rich plasma injection in treatment of idiopathic mild to moderate carpal tunnel syndrome Patients will be classified into…
- Trial name
- NCT05053477
- Testing
- mehylprednisolone injection, pulsed radiofrequency (PRF), platelet-rich plasma
- Where
- 2 sites in Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Infection of Catheter Exit Site, Catheter Related Infection
Alcoholic Chlorhexidine Compared to Povidone Iodine to Limit Perineural Catheter Colonisation
Implementation of perineural catheters may lead to infection by catheter colonization. Catheters may be colonized by the bacteria present on the skin.
- Trial name
- CHLOVEPI (NCT02950246)
- Testing
- perineural catheterization implementation, 2% alcoholic chlorhexidine, povidon iodine
- Where
- France
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Hôpital Raymond Poincaré
Shoulder Surgery, Nerve Block
The Effects of Dexamethasone on Low Dose Interscalene Brachial Plexus Block
A standard interscalene nerve block is performed with long acting local anesthetic (bupivacaine or ropivacaine in concentrations varying from 0.25% to 0.75%).
- Trial name
- ISB-Dex (NCT02322242)
- Testing
- Systemic Dexamethasone, Perineural dexamethasone
- Where
- Canada
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Dr. Stephen Choi
Orthopedic Surgery
Pain Relief After Forefoot Surgery
The aim to test whether continues local anaesthetic infusion via tibial catheter or wound catheter will improve pain relief following forefoot surgery In this sequential prospective randomised, controlled clinical trial,75…
- Trial name
- NCT01019005
- Testing
- Catheter
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Carpal Tunnel Syndrome
Platelet Rich Plasma for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT03184688
- Testing
- platelet rich plasma, Normal saline
- Where
- Taiwan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Intermetatarsal Neuroma
Compare Ultrasound Assisted Cold Therapy and Lidocaine Injection to Treat Morton's Neuroma
The purpose of this study is to evaluate the effectiveness of a device that delivers freezing temperature compared to injecting lidocaine (an anesthetic medication) in providing pain relief to patients with disorganized nerve…
- Trial name
- NCT02838758
- Testing
- Cryoablation, Lidocaine, Saline
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai