Clinical trials: Personalized Nutrition
Obesity Prevention
Better4All Personalized Intervention Pilot Study
The BETTER4U project (Preventing obesity through Biologically and bEhaviorally Tailored inTERventions for you) is funded by the European Union (EU) and involves an international consortium consisting of 28 partners across Europe…
- Trial name
- BETTER4ALL (NCT07120802)
- Testing
- BETTER4U Mobile App and Wearable Use (End-User Group), BETTER4U Intervention Platform Testing (Implementer Group)
- Where
- 7 sites in Cyprus, France and 5 more
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Overweight and Obesity
The Alberta FYBER (Feed Your Gut Bacteria morE fibeR) Study
Too much body-fat has been linked to a low-grade inflammation throughout the body. This inflammation is thought to then cause different diseases, like heart disease and diabetes.
- Trial name
- NCT02322112
- Testing
- Microcrystalline Cellulose Supplementation, Acacia Gum Supplementation, Resistant Starch Type 4 Supplementation
- Where
- Canada
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Health Behavior
Experiences With a Genetic Test for Personalized Nutrition Test for Personalized Nutrition
The investigators will use a web-based survey to collect data on individual attitudes and self-reported health behaviour changes following genetic testing for personalized nutrition.
- Trial name
- NCT02440698
- Testing
- Genetic test for personalized nutrition
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diet Habit
Biomarkers of Food Intake Using a Cross-over Feeding Study
Assessment of dietary intake is key for understanding the links between diet and health. Here, researchers will study molecules in urine samples to give them an insight into what people have eaten.
- Trial name
- NCT03855098
- Testing
- Biomarkers of Fruit and Vegetable Intake
- Where
- Ireland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Crohn Disease
Decoding Personalized Nutritional, Microbiome and Host Patterns Impacting Clinical and Prognostic Features in Crohn's Disease
This is a three-arm, non-interventional observational study designed to investigate the relationship between Crohn's disease (CD), the microbiome, and diet in children.
- Trial name
- NCT04283864
- Testing
- endoscopy examination
- Where
- 8 sites in Canada, Croatia and 5 more
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Weizmann Institute of Science
Food Habits
Food & You: A Healthy Diet Through Algorithms
Food \& You is a large-scale citizen science research project in Switzerland. With this project, the researchers want to confirm that individuals respond differently to food, that is, that the blood sugar response (the level of…
- Trial name
- FoodAndYou (NCT03848299)
- Testing
- Experimental: Single Arm
- Where
- Switzerland
- Volunteers
- 1,782 people, healthy volunteers welcome
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Child Allergy, Allergic Reaction
Development of Personalized Balanced Nutrition Concept Through an IT Platform
By achieving effective cooperation between the Children's Hospital Srebrnjak (CHS), the Reference center for clinical allergology in children of the ministry of health, and IN2 Ltd., part of Constellation Software Inc., it is…
- Trial name
- NCT05462444
- Testing
- Skin prick test
- Where
- Croatia
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Srebrnjak
Obesity, Pre-diabetic
Personalized Glucose Optimization Through Nutritional Intervention
Maintaining well-controlled blood glucose concentrations is essential in the prevention of chronic cardiometabolic diseases. The blood glucose response to dietary and/or lifestyle patterns may vary between individuals.
- Conditions
- Obesity, Pre-diabetic, Type 2 Diabetes Mellitus
- Trial name
- PERSON (NCT03708419)
- Testing
- Optimal diet, Suboptimal diet
- Where
- 2 sites in Netherlands
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy, Overweight, Obese
Food4GutMarKIT - Evaluation of a Tailored Personalized Food Concept for a Healthy Gut Microbiota and Validation of Biomarkers for Monitoring of Its Effects
The overall aim in this "proof-of-concept" study is to evaluate if a diet concept, based on foods that have individually been reported to beneficially affect gut microbiota in fact has an effect on gut microbiota composition and…
- Trial name
- NCT05112276
- Testing
- Diet
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chalmers University of Technology
Personalized Nutrition
N=1 Trials of Individual Variability in Post-prandial Glycemic Responses to Diets of Varying Macronutrient Composition
The key objective of this study is to identify the most suitable diet (i.e. high protein, high fat, low GI, high GI) for an individual.
- Trial name
- NCT05402085
- Testing
- High Protein Diet, High Fat Diet, High Carbohydrate-Low Glycemic Index Diet
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Homeostasis, Metabolism and Nutrition Disorder
Energy Metabolism Profiles Over Weight-loss and Eating Responses
This is an exploratory controlled before-after study, which involves 112 participants, of whom 28 are with normal weight and 84 are overweight or obese.
- Conditions
- Homeostasis, Metabolism and Nutrition Disorder, Healthy, Obesity
- Trial name
- NCT05785221
- Testing
- General lifestyle and nutritional education, Personalized nutritional and lifestyle weight reduction intervention
- Where
- China
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Postprandial Hyperglycemia, Metabolic Disorder, Glucose
Westlake N-of-1 Trials for Macronutrient Intake 2 ( WE-MACNUTR 2)
Diet and nutrition are key to maintain human health. Westlake N-of-1 Trials for Macronutrient Intake (WE-MACNUTR) trial investigates individualized postprandial glycemic responses to different proportions of dietary fat and…
- Trial name
- NCT05161182
- Testing
- High fat, low carbohydrate diet, Low fat, high carbohydrate diet
- Where
- China
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Westlake University
Menopause, Postmenopausal Disorder
Metabotyping in the Postmenopausal Stage
Menopause is defined as the absence of menstrual periods for twelve consecutive months. Although the onset may vary, natural menopause occurs between the ages of 45 and 55 and is considered a stage in the aging process for women.
- Conditions
- Menopause, Postmenopausal Disorder, Postmenopausal Symptoms
- Trial name
- SHE-HEALTH (NCT05397015)
- Testing
- No intervention will be done
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Diabetes, Heart Diseases
PREDICT 2: Personalized Responses to Dietary Composition Trial 2
Foods in the human diet can affect the development of diseases over time, such as diabetes or heart disease. This is because the amount and types of foods in the diet eat can affect a person's weight, and because different foods…
- Conditions
- Diabetes, Heart Diseases, Diet Habit, Diet Modification
- Trial name
- NCT03983733
- Testing
- Dietary Intervention
- Where
- United States
- Volunteers
- 1,139 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
Diet, Healthy, Metabolic Disease
Interactions Between Diet, Microbiome and Abiotic Conditions in the Gut
The aim of this study is to explore the interplay between environmental (abiotic) factors in the gut and the gut microbiota composition, diversity and metabolism.
- Trial name
- PRIMA (NCT04804319)
- Testing
- 9-days habitual diet
- Where
- Denmark
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Diabetes Mellitus, Type 2, Pre-diabetes
Models of Nutrition From Continuous Glucose Monitors
With this study, researchers want to conduct ambulatory studies in which people (healthy, with T2D, or at-risk of T2D) will consume a variety of pre-set and conventional meals in free-living conditions while wearing one or more…
- Conditions
- Diabetes Mellitus, Type 2, Pre-diabetes, Diet Habit, Diet, Healthy
- Trial name
- NCT04991142
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Non Dependant 60 to 75 Year-old Men and Women
Multidimensional Phenotyping Towards Personalized Preventive Nutritional Support for Elderly People
There is high inter-individual variability in the response to feeding, which is determined by multiple interacting factors such as age, sex, genotype, gut microbiota, eating behaviors, physical activity or even socio-demographic…
- Trial name
- MetabotypAGE (NCT06163794)
- Testing
- Nutritional postprandial test
- Where
- 3 sites in France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Diabetes, Heart Diseases
Personalized Responses to Dietary Composition Trial 3
The PREDICT 3 study will build on previous research in over 2,000 individuals to further refine machine learning models that predict individual responses to foods, with the aim of advancing precision nutrition science and…
- Conditions
- Diabetes, Heart Diseases, Diet Habit, Diet Modification
- Trial name
- NCT04735835
- Testing
- Dietary Intervention
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 250,000 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
Malnutrition, Child
The Effect of Continuous Egg Supplement on Personalized Nutri-omics in Primary School Children (SI-EGG STUDY)
This research compares the effects of one-year continuous whole egg supplement vs. egg yolk substitutes and control on anthropometry, biochemical blood parameters, metabolic enzymes and microbiome data in primary school children.
- Trial name
- NCT04896996
- Testing
- whole eggs, yolk-free egg substitutes
- Where
- Thailand
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Overweight and Obesity
Effectiveness of a Precision Diet Based on Gene Expression Versus a Personalized Mediterranean-Style Diet in Weight Loss
The present randomized controlled trial aims to evaluate the relationship between gene expression profiling and the response to a precision diet compared to a personalized Mediterranean-style diet (control diet) in metabolically…
- Trial name
- NCT06435325
- Testing
- Precision diet, Control diet
- Where
- Spain
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau