Clinical trials: Phosphorus Metabolism Disorders
Hyperphosphatemia
Bioequivalence Study of BAY77-1931 Granule
The study is conducted as a randomized, non-blinded, 2-way crossover study. Target population is 60 Japanese healthy male adult subjects selected by screening examination which will be conducted within 4 weeks before the first…
- Trial name
- NCT01053676
- Testing
- Lanthanum Carbonate (Fosrenol, BAY77-1931) Granule, Lanthanum Carbonate (Fosrenol, BAY77-1931) Chewable tablet
- Where
- Japan
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Bayer
Hypophosphatemia
FGF-23 Suppressibility by Calcitonin
Introduction: Based on our experience with calcitonin as an FGF-23 suppressive agent in a patient with an FGF-23 producing tumor we hypothesize that calcitonin may be a physiologically important regulator of FGF-23 production and…
- Trial name
- NCT00688077
- Testing
- Calcitonin
- Where
- Netherlands
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Phosphorus and Calcium Disorders, Parathyroid Diseases
Serum Calcium to Phosphorous (Ca/P) Ratio in the Diagnosis of Ca-P Metabolism Disorders: a Multicentre Study
Primary hyperparathyroidism (PHPT) and Hypoparathyroidism (HP) are two of the most frequent disorder of Calcium-Phosphorus (Ca-P) metabolism.
- Conditions
- Phosphorus and Calcium Disorders, Parathyroid Diseases, Hyperparathyroidism, Hypoparathyroidism
- Trial name
- NCT03747029
- Testing
- No intervention is provided
- Where
- Italy
- Volunteers
- 1,038 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Postprandial Hyperglycemia, Energy Expenditure
The Effect of Bread Fortification With Phosphorus and Lysine on Postprandial Glycaemia and Thermogenesis
Wheat and wheat derived products are highly consumed around the world. They constitute the major dietary source of protein and energy for many individuals.
- Trial name
- NCT03836495
- Testing
- lysine and phosphorus
- Where
- Lebanon
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Metabolic Syndrome, Insulin Sensitivity
Effect of Phosphorus Additives on the Metabolome in Healthy Adults
This study evaluates the effect of phosphorus supplementation on the human metabolome. The investigators will do so by conducting a cross-over study in healthy adults consuming a study diet (normal diet supplemented by neutral…
- Conditions
- Metabolic Syndrome, Insulin Sensitivity, Cardiovascular Diseases
- Trial name
- NCT03841786
- Testing
- Phosphorus-supplemented study diet, Control Diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Familial Hypophosphatemic Rickets
Calcimimetics in Hypophosphatemic Rickets
Currently, large oral doses of phosphate and 1,25(OH)2D (calcitriol) are the standard treatment of patients with familial hypophosphatemic rickets (XLH).
- Trial name
- CHR (NCT00844740)
- Testing
- Cinacalcet
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
AV Fistula
av Fistula Patency Loss as a Cause of Fistula Failure and Hyperphosphatemia
Assessment of arteriovenous fistula patency loss which leads to av fistula failure and its relation to high serum phosphate level in chronic hemodialysis patients.
- Trial name
- NCT05569109
- Testing
- doppler ultrasound
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hyperglycemia, Glucose Metabolism Disorders
Effect of Lysine and Phosphorus Fortification on Glycemic Index and Postprandial Glycemia in Double Fortified Bread
The goal of this clinical trial is to investigate the effect of lysine and phosphorous on the glycemic index (GI) of white bread and postprandial glycemia.
- Conditions
- Hyperglycemia, Glucose Metabolism Disorders, Metabolic Disease, Glycemic Index
- Trial name
- LP-DFB-GI-PG (NCT05903625)
- Testing
- Control Group - Standard White Bread, Lysine Group - Lysine-Fortified Bread, Phosphorus Group - Phosphorus-Fortified Bread
- Where
- Pakistan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Heart Failure, Sarcopenia
The Sarcopenia Study
The goal of this cross-sectional study is to investigate the prevalence of sarcopenia in patients with Heart Failure. The main question it aims to answer is: Whether there is a difference in the prevalence of sarcopenia across…
- Conditions
- Heart Failure, Sarcopenia, Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction
- Trial name
- NCT05888688
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Asthma, Vitamin D Resistant Rickets
Assessment Of Vitamin D Role In The Pathogenesis Of Asthma In Vitamin D Resistent Patients
Research Title: Evaluation of airway reactivity, allergy and inflammatory mediators in exhaled breath condensate in vitamin D resistant rickets.
- Trial name
- NCT01578824
- Testing
- Methacholine Challenge Test
- Where
- Israel
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Refeeding Syndrome
The Effect of a Diet Based on Low Sodium and Slowly Absorbed Carbohydrates on the Incidence of Refeeding Syndrome in Patients With Head and Neck Cancer
The study is based on a master thesis which showed that 72% of patients with head and neck cancer admitted to a Danish hospital (Rigshospitalet, Copenhagen) developed refeeding syndrome after admission.
- Trial name
- NCT01845922
- Testing
- Low sodium diet
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Phosphorus Metabolism Disorders
Dietary Phosphate and Serum Phosphorus
Overall study design is to review National Health and Nutrition Examination Survey (NHANES) data 1999-2008 for nutrition risk according to kidney function.
- Trial name
- NCT02435017
- Volunteers
- 7,895 people, healthy volunteers welcome
- Sponsor
- Linda W. Moore
Obesity
The Role of Phosphorus in Diet Induced Thermogenesis (DIT) of Both Lean and Obese Subjects
The study aim at: Investigating the impact of phosphorus ingestion on DIT of lean and obese subjects consuming high carbohydrate meal.
- Trial name
- PinDIT (NCT02482142)
- Testing
- Effect of phosphorus
- Where
- Lebanon
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Hyperphosphatemia
The Effect of Magnesium Oxide on Plasma Phosphate in Hemodialysis Patients
Hyperphosphatemia is a common problem in hemodialysis (HD) patients. Different chelators for control of Hyperphosphatemia are used.
- Trial name
- NCT01854437
- Testing
- Mg Oxide
- Where
- Iran
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Phosphate Diabetes, X-linked Hypophosphatemia
Phosphorus-31 Spectroscopy in Phosphate Diabetes
Phosphate diabetes is defined by urinary phosphate wasting due to impaired tubular reabsorption. It can be classified based on either a genetic or acquired origin.
- Trial name
- Phos-ATP (NCT06921720)
- Testing
- intra-muscular ATP values in phosphate diabetes, intra-muscular phosphate values in phosphate diabetes
- Where
- 2 sites in France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Healthy, Chronic Kidney Diseases
Effect of the Consumption of Ferric Hydroxide Adipate on Urinary Phosphorus Excretion.
Ferric hydroxide adipate is a ferric iron supplement containing iron hydroxide and a dietary organic acid that was developed at MRC Human Nutrition Research.
- Trial name
- NCT01991574
- Testing
- Calcium acetate, Iron Hydroxide Adipate
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical Research Council
Hypophosphatemia, Chronic Kidney Diseases
Investigation of Hypophosphataemia Following Intravenous Iron
Anaemia (low haemoglobin levels) can develop in a number of conditions, including chronic kidney disease (CKD) and intestinal conditions (e.g. inflammatory bowel disease, intestinal failure).
- Conditions
- Hypophosphatemia, Chronic Kidney Diseases, Intestinal Disease, Anemia
- Trial name
- NCT04502784
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Belfast Health and Social Care Trust
Hypophosphataemia, Osteopenia of Prematurity
Investigating a New Way of Giving Medicine to Newborn and Preterm Babies
There is a deficit in the number of 'age-appropriate' formulations available for the delivery of medicines to children. Liquid preparations are considered the 'gold standard' for delivering medicines to children however many of…
- Trial name
- NCT01676844
- Testing
- Oral thin film therapy (Potassium acid phosphate oral thin films), Standard therapy (Potassium acid phosphate oral solution)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Strathclyde
Hyperphosphatemia, Chronic Kidney Disease
Drug-Drug Interaction Study to Evaluate the Effect of Colestilan on the Pharmacokinetics of Single Doses of Candesartan Cilexetil in Healthy Subjects
The primary objective is to assess the effects of colestilan on the pharmacokinetic profile of candesartan cilexetil when administered at the same time as, 1 hour before, and 3 hours after the first daily dose of colestilan…
- Trial name
- NCT01976572
- Testing
- colestilan, candesartan
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Tanabe Pharma Corporation