Clinical trials: Photobiomodulation
Dry Eye, Meibomian Gland Dysfunction (Disorder)
Effect of Low-Level Light Therapy on Ocular Surface Parameters in Patients Undergoing Femto-Lasik Surgery
This study evaluates the role of perioperative low-level light therapy (LLLT) in reducing dry eye disease (DED) symptoms after femtosecond laser-assisted in situ keratomileusis (Femto-LASIK).
- Conditions
- Dry Eye, Meibomian Gland Dysfunction (Disorder), Ocular Surface Disease
- Trial name
- LLLT-Lasik (NCT07181668)
- Testing
- Low-Level Light Therapy
- Where
- Romania
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Malocclusion
The Effect of OrthoPulse™ Photobiomodulation on Tooth Movement and Treatment Time When Used With Invisalign Treatment
The aim of the study is to determine if, and to what degree photobiomodulation treatment with OrthoPulse has an effect on the rate of tooth movement during alignment for patients receiving Invisalign orthodontic aligner treatment.
- Trial name
- NCT02954133
- Testing
- Invisalign (7 day), Invisalign (5 day), OrthoPulse
- Where
- 4 sites in United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Healthy Volunteers
Effect of Transcranial Near InfraRed Light on Cerebral Function in Young and Healthy Older Subjects: a FMRI Study (TIROC)
Numerous studies have shown that the extra-cranial application of near infrared light (λ=600-1000nm) (also called transcranial photobiomodulation or tPBM), has a positive impact on brain function in both humans and experimental…
- Trial name
- TIROC (NCT05845216)
- Testing
- ACTIVE Transcranial photobiomodulation (tPBM)
- Where
- France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Molar, Third, Low-level Laser Therapy
"Effectiveness of Dual-Wavelength Laser Therapy in Third Molar Extraction Pain, Swelling, and Trismus"
Objective: To investigate the effects of single session dual wavelength low dose laser therapy to be applied after third molar tooth extraction on postoperative pain, edema and physical activities.
- Trial name
- NCT05992233
- Testing
- Dual wavelength low level laser
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Anterior Knee Pain, Photobiomodulation (PBM)
Photobiomodultion in Anterior Knee Pain
The goal of this clinical trial is to assess the augmented recovery in the adolescent females with patellar tendinopathy using Phot- Biomodulation
- Conditions
- Anterior Knee Pain, Photobiomodulation (PBM), Laser Therapy
- Trial name
- PBM (NCT07865325)
- Testing
- Photobiomodultion with Laser scanning, patellar mobilization with exercise therapy
- Where
- Jordan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- New Ismailia National University
Distal Radius Fracture
Home-Based Photobiomodulation Effects in the Postoperative Period of Distal Radius Fractures
This double-blind, randomized controlled clinical trial aims to evaluate the adjuvant effect of home-based photobiomodulation (PBM) therapy on the rehabilitation of surgically treated DRFs combined with an unsupervised home…
- Trial name
- NCT07426926
- Testing
- Open reduction and internal fixation (ORIF) with locked volar plate, Home exercises, Active photobiomodulation
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Low Level Laser Therapy, Performance
Photobiomodulation in Different Doses on Strength Capacities and Functional Performance
Background: Photobiomodulation has been explored for years, with wide clinical use for wound healing and analgesia in varied orthopedic conditions, but the number of research and clinical use has increased during the last decade.
- Conditions
- Low Level Laser Therapy, Performance, Sport
- Trial name
- NCT03860766
- Testing
- Photobiomodulation
- Where
- Brazil
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Trigeminal Neuralgia
Effect of Non-invasive Photobiomodulation Therapies in Patients With Trigeminal Neuralgia
The aim of this study was to compare the effectiveness of two different photobiomodulation (PBM) therapies as an alternative to medical treatment to reduce pain and improve quality of life in patients with trigeminal neuralgia…
- Trial name
- NCT06440356
- Testing
- laser therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Low Back Pain
Application of LED Photobiomodulation in the Treatment of Chronic Low Back Pain
Lumbar pain, or low back pain, may be defined as pain or discomfort located from the lower portion of the costal margin to the gluteal folds, with or without referred pain in the legs.
- Trial name
- NCT04003545
- Testing
- LED Photobiomodulation
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Muscle Recovery, Exercise
Photobiomodulation on Recovery in Female Futsal Athletes
The aim of this study is to investigate the effects of photobiomodulation therapy (PBMT) on recovery after high-intensity, intermittent exercises in female futsal athletes.
- Conditions
- Muscle Recovery, Exercise, Phototherapy, Futsal
- Trial name
- PBMT (NCT07511803)
- Testing
- Active PBMT
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidade Norte do Paraná
Bruxism, Sleep
Evaluation of the Effectiveness of Infrared LED Photobiomodulation in Children With Sleep Bruxism
Sleep bruxism is a masticatory muscle activity characterized as rhythmic (phasic) or non-rhythmic (tonic). The literature reports the prevalence rates, diverse etiologies and different types of treatment.
- Trial name
- NCT03710174
- Testing
- Infrared LED photobiomodulation, Occlusal splint
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Oral Mucositis
A Study to Describe the Effect of Photobiomodulation (Low Level Laser Therapy) in Reducing the Severity and Incidence of Oral Mucositis (Oral Ulceration) in Oral Cancer Patients Undergoing Radiation Treatment
The goal of this study is to describe the effect of photobiomodulation (PBM) on the incidence and severity of oral mucositis in post-operative oral cancer patients receiving radiotherapy +/- chemotherapy.
- Trial name
- PBM (NCT07387978)
- Testing
- photobiomodulation
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peter MacCallum Cancer Centre, Australia
Subcutaneous Fat Disorder
Combination of Light and Ultrasound to Reduce Abdominal Fat
Light and ultrasound can be interesting alternatives to reduce abdominal fat. Thus, the main objective of this study will be to evaluate the effects of these isolated techniques and their association in subcutaneous abdominal…
- Trial name
- NCT05155683
- Testing
- Photobiomodulation (PBM) with infrared LED, Low-frequency ultrasound (LOFU), Muscle electrostimulation
- Where
- Brazil
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Periodontitis, Lasers
The Effect of Adjunctive Therapies in Regenerative Treatment of Stage III Grade C Periodontitis
Anti-infective procedures play a very important role in the success of regenerative surgical treatment of aggressive periodontitis, Grade C periodontitis, which shows the newly named molar-incisor pattern according to the 2017…
- Conditions
- Periodontitis, Lasers, Ozone, Wound Healing
- Trial name
- NCT05447026
- Testing
- Control group, Antimicrobial photodynamic therapy (aPDT) group, LED photobiomodulation group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Gazi University
Malocclusion
The Effect of OrthoPulse Photobiomodulation on the Rate of Tooth Movement During Alignment With Fixed Appliances
The aim of this study is to determine efficacy of OrthoPulse photobiomodulation on the rate of tooth movement during alignment for Subjects receiving fixed appliance orthodontic treatment.
- Trial name
- NCT03202355
- Testing
- Fixed Appliance Orthodontic Treatment, OrthoPulse™
- Where
- 3 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Low Back Pain, Hydrotherapy
Effects of Photobiomodulation and Deep Water Running Training in Subjects With Low Back Pain.
Physical exercises proves to be an option to revert a vicious cycle and aggravation of the painful that chronic low back pain can provide, which can improve the mobility and stabilization of the spine, muscle strength, motor…
- Conditions
- Low Back Pain, Hydrotherapy, Exertion; Excess
- Trial name
- NCT03465228
- Testing
- Training and LED group, Training group, LED group
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidade Norte do Paraná
Pediatric Sleep Apnea, Obstructive Sleep Apnea
Photobiomodulation for Pediatric Hypertrophic Tonsils
Pediatric obstructive sleep apnea is a medical condition where a child has great difficulty with breathing, or stops breathing all together, while asleep.
- Conditions
- Pediatric Sleep Apnea, Obstructive Sleep Apnea, Tonsils Hypertrophy
- Trial name
- NCT05459935
- Testing
- PBM Tonsil Arm
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Muscle Performance, Exercise
Photobiomodulation on Performance in Female Futsal Athletes
The aim of this study is to investigate the effects of photobiomodulation therapy (PBMT) on physical performance in female futsal athletes.
- Conditions
- Muscle Performance, Exercise, Phototherapy, Futsal
- Trial name
- PBMT (NCT07511790)
- Testing
- Active PBMT
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidade Norte do Paraná
Labor Pain
Effect of LED Photobiomodulation on Analgesia During Labor
The aim of this study is to valuate the effects of LED photobiomodulation on analgesia during labor.ight-emitting diode (LED) photobiomodulation is an effective and noninvasive alternative to pharmacological methods.n total, 60…
- Trial name
- EPAL (NCT03496857)
- Testing
- Light emitting diode, Bath Therapy
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Alveolar Bone Loss, Maxillary Sinus Bone Loss
Anti-HLA Antibodies After Bone Regeneration Surgery
This study evaluates the occurrence of anti-human leukocyte antigen (anti-HLA) antibodies following bone regeneration procedures performed prior to dental implant therapy.
- Trial name
- Anti-HLA Bone (NCT07474857)
- Testing
- Xenogeneic Bone Graft, Allogeneic Bone Graft, Low-Level Laser Therapy
- Where
- Poland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical Innovation Center Wroclaw