Clinical trials: Physical Frailty
Post-operative Delirium
Interest in Combining Intraoperative ElectroEncephaloGram (EEG) With Assessment of Frailty to Predict Postoperative Delirium in Patients Aged >75 Years Undergoing Major Non-cardiac Surgery
Post-operative delirium (POD) is known to be independently associated with pre-operative frailty, pre-operative cognitive status and per-operative ElectroEncephaloGram (EEG).
- Trial name
- NCT06510140
- Testing
- Detection of the Post-operative delirium (POD)
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Dependency
Comprehensive Geriatric Assessment for Frail Older People
The study "Comprehensive Geriatric Assessment for frail older people in Swedish acute care settings - a randomized controlled study" comprised two study arms: one intervention and one control group.
- Trial name
- NCT02773914
- Testing
- Comprehensive Geriatric Assessment
- Where
- Sweden
- Volunteers
- 155 people
- Sponsor
- Göteborg University
Cognitive Frailty
The Effect of Dual Tasks of Digital Technology on Cognitive Function and Physical Activity in the Older Adults With Cognitive Frailty
Background: Cognitive frailty is a state that combines physical weakness and cognitive impairment. As age increases, the prevalence rate also increases.
- Trial name
- NCT06797440
- Testing
- Dual tasks of digital technology
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Frailty, Frailty Syndrome
Prevalence, Determinants and Natural History of Frailty and Pre-frailty in Elderly People
Frailty syndrome (i.e. frailty) is a geriatric syndrome which relies on the reduction of multisystem reserve capacity. Frail people have a lower potential to respond to external stressors and various life incidents as well as…
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome, Fragility
- Trial name
- FRAILPOL (NCT04518423)
- Where
- Poland
- Volunteers
- 1,093 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Frail Elderly Syndrome
A Study of the Intervention Effect of a Hybrid Exercise Program on Frail Elderly
The declining physical condition of frail elderly is becoming an ugent problem. Although the exercise intensity of Wu Qin Xi appears to be low, it is highly effective in the older individuals.
- Trial name
- NCT05832853
- Testing
- Wu Qin Xi exercise, Wu Qin Xi, resistance training and endurance training, Resistance training and endurance training
- Where
- China
- Volunteers
- 181 people
- Sponsor
- Guang Yang, Prof. Dr.
Healthy Aging, Frailty
Characterisation of Functional and Cognitive Responses Following Olfactory Stimulation and/or Functional Training in Older Adults.
This randomized controlled trial will evaluate the effects of olfactory stimulation and/or multicomponent physical training in adults aged 60 years and older.
- Conditions
- Healthy Aging, Frailty, Cognitive Decline, Olfactory Dysfunction
- Trial name
- INNOLFACT 2 (NCT07623122)
- Testing
- Olfactory stimulation, Multicomponent physical training, Combined olfactory stimulation and multicomponent physical training
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fundacion Miguel Servet
Fibromyalgia, Old Age; Debility
Frequency of Fibromyalgia Syndrome in Elderly Patients Aged 80 and Above and Its Relationship With Geriatric Parameters
The aim of this study was to determine the prevalence of fibromyalgia syndrome in patients aged 80 years and over and to examine the relationship between detailed geriatric assessment parameters and fibromyalgia syndrome.
- Trial name
- NCT06969716
- Testing
- Detailed geriatric assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Sultan 1. Murat State Hospital
Parkinson Disease, Physical Therapy Modalities
Home Physiotherapy in Frailty in Patients With Parkinson's Disease
The aim of this protocol is to evaluate the effects of a home-based therapeutic exercise program applied in patients with PD to reverse frailty. The design of this study is experimental, prospective, randomized and single blind.
- Conditions
- Parkinson Disease, Physical Therapy Modalities, Frailty
- Trial name
- NCT05607862
- Testing
- Home Physiotherapy Group, Control Group
- Where
- Spain
- Volunteers
- 13 people
- Sponsor
- University of Oviedo
Frailty
Validation of a Frailty Self Assessment Tool
The number of elderly is increasing throughout of the world. Aging is associated with increasing diseases that may be preventable. Over the last decades, frailty has emerged as one of the major risk factors for loss of autonomy.
- Trial name
- NCT04085432
- Testing
- Self administered questionnaire and Clinical evaluation
- Where
- 2 sites in France
- Volunteers
- 5,134 people, healthy volunteers welcome
- Sponsor
- International Longevity Centre France
Frailty, Sleep Quality
Acupoint Stimulation and Exercise for Taiwanese Pre-frail Older Adults
This study aims to explore the relationships between frailty, daily physical activity, sleep quality, and Traditional Chinese Medicine (TCM) constitutions among older adults in Taiwan.
- Conditions
- Frailty, Sleep Quality, Aging
- Trial name
- NCT07732530
- Testing
- Vivifrail Exercise Program, Acupoint Stimulation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Tainan Hospital, Ministry of Health and Welfare
Physical Disability, Cardiovascular Risk Factors
Study on Cardiovascular Health, Nutrition and Frailty in Older Adults in Spain
The purpose of this study is to examine the association between ideal cardiovascular health, diet and other lifestyles, biological risk factors, either well-established or emergent, and the risk of frailty in older adults…
- Trial name
- Seniors-ENRICA (NCT02804672)
- Where
- Spain
- Volunteers
- 1,566 people
- Sponsor
- Universidad Autonoma de Madrid
Lung Cancer, Esophageal Cancer
Assessment of Patient Frailty Prior to Thoracic Surgery
Determine the feasibility of assessment of measures of frailty and determine if these measures provide a clinically important contribution of risk assessment in a population of patients undergoing major thoracic surgery for lung…
- Trial name
- NCT02803281
- Testing
- Frailty Assessment
- Where
- 3 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Frailty, Fall
Validation and Application of a Multi-dimentional Frailty Assessment Tool-Cohort Intervention and Follow up
We aim to (1) use a multifaceted, frailty assessment model. (2) use randomized controlled trials to deal with and intervene with cross-field, multi-faceted and intelligent remote management strategies for the elderly with…
- Conditions
- Frailty, Fall, Sarcopenia
- Trial name
- NCT05731167
- Testing
- Multidomain frailty prevention method, Regular follow up
- Where
- Taiwan
- Volunteers
- 216 people
- Sponsor
- National Taiwan University Hospital
Frailty
FOCUS- Frailty Management Optimization Through EIP AHA Commitments and Utilization of Stakeholders Input
This intervention study is a part of the FOCUS (Frailty Management Optimization Through EIP AHA Commitments and Utilization of Stakeholders Input) project which purpose is to critically reduce the burden of frailty in Europe by…
- Trial name
- FOCUS-WMU (NCT03194412)
- Testing
- Diet /nutritional, Physical activity, Comprehensive therapy
- Where
- Poland
- Volunteers
- 210 people
- Sponsor
- Wroclaw Medical University
Depression, Old Age; Debility
Assessment of Depression Levels in Elderly Patients With an Orthopedic Fracture Compared to Patients After a Stroke.
Depression is common among elderly patients hospitalized due to acute conditions like strokes or osteoporotic fractures. It has significant impacts on quality of life, hospitalization rates, and mortality.
- Conditions
- Depression, Old Age; Debility, Stroke, Fractures, Bone
- Trial name
- NCT06570356
- Testing
- Geriatric Depression Scale - 15
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shmuel Harofeh Hospital, Geriatric Medical Center
Acute Lymphoblastic Leukemia, Brain Tumor
A Longitudinal Assessment of Frailty in Young Adult Survivors of Childhood Cancer
Advances in cancer therapies have led to increasing numbers of adult survivors of pediatric malignancy. Unfortunately, treatment of childhood cancer continues to require agents designed to destroy malignant cell lines, and normal…
- Conditions
- Acute Lymphoblastic Leukemia, Brain Tumor, Hodgkin Lymphoma
- Trial name
- NCT02256137
- Where
- United States
- Volunteers
- 1,564 people
- Sponsor
- St. Jude Children's Research Hospital
CGA, Comprehensive Geriatric Assessment
Exploring the User Experience of CGA-Q
As people become older they may start to have more than one health issue at one time. Geriatricians are doctors who specialise in looking after older people.
- Conditions
- CGA, Comprehensive Geriatric Assessment, Person Centred Care, Frailty
- Trial name
- NCT06646575
- Testing
- Qualitative data, no intervention
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Frailty
AI-based Frailty Assessment Tool for Patients Undergoing Cardiac Surgery
The main purpose of this study is to establish a frailty automatic evaluation index "AI frailty index" based on artificial intelligence multi-modal non-contact monitoring information analysis.
- Trial name
- NCT06096922
- Testing
- No intervention
- Where
- China
- Volunteers
- 521 people
- Sponsor
- China National Center for Cardiovascular Diseases
Enteral Nutrition
Assessment of the Effects of Probiotic Supplementation on Gut Microbiota Composition and Short-chain Fatty Acid Production in Frail Elderly Patients Receiving Home Enteral Nutrition With an Oligomeric Formula.
This is an investigator-initiated, spontaneous, non-profit, randomized intervention study with two parallel arms. The study aims to evaluate the effect of a 30-days probiotic supplementation on the composition of the intestinal…
- Trial name
- MICROBIOTA (NCT07437352)
- Testing
- probiotic supplementation
- Where
- Italy
- Volunteers
- 27 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Tricuspid Regurgitation, Tricuspid Valve Insufficiency
Evaluation of the Impact of Interventional Treatments for Symptomatic, Severe Tricuspid Valve Insufficiency on Renal Integrity and Function, as Well as on Physical Function and Activity in Older Adults.
The hypothesis is that renal function will improve following tricuspid valve intervention. A reduction in renal biomarkers is also expected.
- Conditions
- Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Cardio-Renal Syndrome, Frailty
- Trial name
- TriRenGe (NCT07464106)
- Testing
- Transcatheter edge-to-edge repair (TEER)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Robert Bosch Medical Center