Clinical trials: Physical Frailty
Frailty, Frail Elderly Syndrome
Frailty Assessment in Vascular Hot Clinic Setting - Feasibility and Prognostic Value
A single-centre prospective study of feasibility assessing the suitability of introducing routine frailty screening in a controlled, and reproducible, outpatient department setting for Vascular Surgery patients.
- Conditions
- Frailty, Frail Elderly Syndrome, Surgery
- Trial name
- FAVOUR (NCT06040658)
- Testing
- Frailty assessment
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Frailty
Understanding Changes in Physical Function Using Principles of Precision Medicine
This is a pilot, feasibility study and the purpose of this study is exploratory. The goal is to provide the PI and study team with data using metabolomics that can be used to: a) demonstrate an ability to use such data in a…
- Trial name
- NCT05581082
- Testing
- Pragmatic, exploratory study of Precision Medicine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Frail Elderly Syndrome
Validation of a Record-based Frailty Assessment According to the Multidimensional Prognostic Index
Background Various phenotype and cumulative frailty assessment tools have been developed and compared in research. For use in an in-hospital setting, a cumulative and graded frailty assessment method is preferred in order to…
- Trial name
- NCT03794674
- Testing
- No intervention.
- Where
- Denmark
- Volunteers
- 92 people
- Sponsor
- University of Aarhus
Frailty, Kidney Transplant; Complications
Frailty Assessment Among Kidney Transplant Candidates
Frailty is common among chronic kidney disease patients who are on the kidney transplant (KT) waiting list. The aim of this study is to assess frailty according to different frailty tools among KT candidates and to establish…
- Trial name
- Mar-Kid (NCT04811417)
- Volunteers
- 500 people
- Sponsor
- Parc de Salut Mar
Hematologic Malignancy, Old Age; Debility
Nutritional and Physical Exercise Intervention in Older Patients With Malignant Hemopathies
Clinical trial to analyze the impact of nutrition and physical exercise intervention program on the completion of treatment in older patients 70 years or older with malignant hemopathology
- Trial name
- ICOSENIORHEM (NCT04057443)
- Testing
- Nutritional support, Physical exercise, Hematologic Drug
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Maite Antonio, MD, Phd
Abdominal Surgery, Postoperative Complications
P-POSSUM for Outcomes After Abdominal Surgery
Postoperative complications after abdominal surgery can lead to prolonged recovery, intensive care admission, and death. The P-POSSUM score is a commonly used surgical risk prediction tool, but its performance may vary between…
- Conditions
- Abdominal Surgery, Postoperative Complications, Surgical Risk Prediction, Postoperative Mortality
- Trial name
- PPOSSUM-ABD (NCT07667764)
- Where
- Vietnam
- Volunteers
- 3,000 people
- Sponsor
- Bach Mai Hospital
Kidney Transplant; Complications, Frailty
Effect of Home-based Training Program for Kidney Transplant Recipients (HOMETRAIN-KTR)
Does home-based training work in kidney transplant recipients with reduced physical function? The goal of this clinical trial is to learn if home-based training works to better physical function in adult kidney transplant…
- Conditions
- Kidney Transplant; Complications, Frailty, Physical Disability
- Trial name
- NCT06379009
- Testing
- Training
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Aging, Rehabilitation
Physical Function of Older Citizens During Municipality-based Rehabilitation
When choosing outcomes to assess rehabilitation's effect or progress, it is essential to consider the constructs being measured and their value to the patient and the psychometric properties.
- Conditions
- Aging, Rehabilitation, Frailty, Sarcopenia
- Trial name
- NCT04862481
- Where
- Denmark
- Volunteers
- 115 people
- Sponsor
- University College Absalon
Ovarian Cancer, Chemotherapy
Feasibility of Frailty Assessment and Implementation of Interventions in Women Over 70 With Epithelial Ovarian Cancer
Ovarian cancer is frequently diagnosed in older women, with over half of all new diagnoses being in women over 65 years. Current treatment options are based on the results of clinical trials that often do not include older, less…
- Conditions
- Ovarian Cancer, Chemotherapy, Quality of Life, Tolerance
- Trial name
- FAIR-O (NCT04300699)
- Testing
- Functional Geriatric Assessment
- Volunteers
- 120 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Frailty, Disability Physical
Viability of an Educational Program for Lifestyle Changes and an Algorithm for the Derivation of Exercise Programs in Older People at Risk of Dependency at Primary Care.
According to the INE in 2021, more than 9 million people are currently over 65 years of age. This means that more than 1 million are frail and almost 4 million are pre-fragile only in Spain.
- Conditions
- Frailty, Disability Physical, Old Age; Atrophy
- Trial name
- PRICA-POWFRAIL (NCT05772910)
- Testing
- EDUcation, EXERcise, EDU-EXER
- Volunteers
- 110 people
- Sponsor
- University of Cadiz
Geriatric Oncology, Oncology
G8, CARG, Frailty, and Nutritional Markers in Predicting Chemotoxicity
This study aims to evaluate the ability of G8, CARG, and Frailty scales to predict chemotherapy-related toxicity and the need for G-CSF in elderly cancer patients.
- Conditions
- Geriatric Oncology, Oncology, Nutrition, Nutrition Assessment
- Trial name
- NCT07151794
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Çanakkale Onsekiz Mart University
Diabetes Mellitus, Type 2, Frailty
Power Strength Training in Type 2 Diabetic Mellitus Older Adults
Diabetes is a disease with a high impact in the population older than 65 years old. Some indications suggest that diabetes in the old age aggravate the negative effects of ageing, as the loss of muscle mass and strength, bringing…
- Trial name
- DIAPOW (NCT04332302)
- Testing
- Power resistance training
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- Technical University of Madrid
Frailty At Older Adults
Telerehabilitation on Physical Fitness, Functional Status, and Quality of Life in Frail Older Adults
The goal of this randomized controlled trial (RCT) is to analyze whether the effectiveness of a synchronous telerehabilitation program is better than a face-to-face physical therapy program in improving the physical fitness…
- Trial name
- Teleactivate 3 (NCT06784245)
- Testing
- TeleActivate
- Where
- Chile
- Volunteers
- 58 people
- Sponsor
- Marina Alvarado
Sarcopenia, Kidney Transplantation
Muscle Ultrasound for Sarcopenia Assessment in Kidney Transplant Recipients
This is a single-center prospective observational study designed to evaluate the effectiveness of multimodal muscle ultrasound for the assessment of sarcopenia in kidney transplant recipients.
- Conditions
- Sarcopenia, Kidney Transplantation, Muscle Wasting
- Trial name
- KT-SARC (NCT07607236)
- Testing
- Muscle Ultrasound
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Sichuan Provincial People's Hospital
Type2diabetes, Frail Elderly Syndrome
The Impact of Geriatric Assessment on the Treatment Plan of Elderly Patients With T2DM
Introduction: With the aging of the world population and the increasing incidence of type 2 diabetes mellitus (T2DM) with age, the number of elderly individuals living with diabetes has been considerably rising.
- Conditions
- Type2diabetes, Frail Elderly Syndrome, Frailty, Geriatric Assessment
- Trial name
- NCT06469437
- Testing
- Providing the physicians with a proposed glycated hemoglobin target
- Where
- Brazil
- Volunteers
- 220 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Sedentary Behavior, Frail Elderly Syndrome
Effect of an Intervention on Health in Older Care Home Residents
Care home residents spent 79% of their time being sedentary. Reduced physical activity and lack of mental stimulation causes general weakness and frailty in older adults that can result in increased healthcare needs.
- Conditions
- Sedentary Behavior, Frail Elderly Syndrome, Frailty, Lifestyle, Sedentary
- Trial name
- NCT04659694
- Testing
- Wellness programme provided by Oomph! Wellness company
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bournemouth University
Older People, Non-Communicable Chronic Diseases
A Personalized Prevention Program (PPP) Based on the Comprehensive Geriatric Assessment (CGA) for the Prevention of Multidimensional Frailty Related to Non-communicable Chronic Diseases (NCDs) in Older People
Non-Communicable Diseases (NCDs) can accelerated the aging process and increase the frailty condition The Comprehensive Geriatric Assessment (CGA) is the gold standard in the geriatric clinical context Recently, in Italy the…
- Trial name
- PrimaCare_P3 (NCT06224556)
- Testing
- Brief-MPI assessment (based on the Comprehensive Geriatric Assessment); Personalized Prevention Program
- Where
- 4 sites in Italy
- Volunteers
- 1,216 people
- Sponsor
- Alberto Pilotto
Cardiovascular Diseases, Metabolic Diseases
Healthy Aging Longitudinal Study in Taiwan
The general aim of this study is to establish a longitudinal cohort of older persons in order to examine the physiological, environmental and genetic risk factors for physical disability, frailty, cardiovascular disease, and…
- Trial name
- HALST (NCT02677831)
- Volunteers
- 5,664 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Frail Elderly Syndrome, Frailty
Keeping Active in Residential Elderly
This trial will take the form of a feasibility study; designed to assess the feasibility of a proposed future clinical trial in this setting.
- Conditions
- Frail Elderly Syndrome, Frailty, Physical Activity
- Trial name
- KARE (NCT03141879)
- Testing
- HUR equipment resistance training intervention
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University of Birmingham
Frail Elderly, Physical Activity
Effectiveness of an Intervention in Multicomponent Exercise in Patients Over 70 Years in Primary Care
Objective: To evaluate the effect of a multicomponent physical activity program, compared with the usual medical practice, to reverse prefrailty by Fried in people over 70 years, one year after the end of the intervention.
- Trial name
- MEFAP (NCT03568084)
- Testing
- MEFAP, control usual practice
- Where
- Spain
- Volunteers
- 206 people
- Sponsor
- Gerencia de Atención Primaria, Madrid