Clinical trials: Physical Function in Older Adults
Sarcopenia
Middle Age muScle Krill Study
This study will determine the effect of 6 months of supplementation with krill oil on muscle strength and mass in middle-aged adults.
- Trial name
- MASK (NCT06005064)
- Testing
- Krill oil, Vegetable oil
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Aging, Diabetes Mellitus, Type 2
Effect of GLP1 Receptor Agonists on Physical Function, Body Composition, and Markers of Aging in Older Adults
Semaglutide is a medication approved by the US Food and Drug Administration (FDA) as an antihyperglycemic (a drug that reduces glucoses in those with diabetes) and for weight management.
- Conditions
- Aging, Diabetes Mellitus, Type 2, PreDiabetes, Overweight and Obesity
- Trial name
- NCT05786521
- Testing
- Semaglutide Injectable Product, Lifestyle Counseling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Ageing
Generation 100: Blood Volume and Cardiac Function in Healthy Aging
Hypothesis: Exercise will reduce morbidity and mortality rates in an elderly population. The extent of reduction will be intensity dependent.
- Trial name
- NCT01765816
- Testing
- high intensity interval training, moderate intensity training
- Where
- Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Physical Deconditioning
Shifting Rehabilitation Paradigms in Skilled Nursing Facilities
This study seeks to improve rehabilitation methods for restoring physical function with skilled nursing facility care. More specifically, this study is designed to evaluate the effectiveness of an intensive therapeutic…
- Trial name
- NCT02927171
- Testing
- IntenSive Therapeutic Rehabilitation for Older Skilled Nursing Home Residents
- Where
- 3 sites in United States
- Volunteers
- 104 people
- Sponsor
- VA Office of Research and Development
Health Service for the Aged
Interactive Stepping Exercise on Executive Function and Gait Variability
The present study is to examine the effects of interactive stepping exercise on executive function and gait variability in community-dwelling older adults
- Trial name
- NCT03621267
- Testing
- Interactive Stepping Exercise, Home exercise program
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Yang Ming Chiao Tung University
PND, POCD - Postoperative Cognitive Dysfunction
Effects of Ciprofol on Perioperative Neurocognitive Function in Elderly Patients Undergoing Daytime Surgery
As life expectancy increases, the rate of disability among elderly individuals is also rising. Elderly patients undergoing home-based rehabilitation after surgery without medical supervision may experience complications and…
- Trial name
- NCT07895407
- Testing
- Ciprofol, propofol
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Cough
A Study of Camlipixant in Male and Female Healthy Participants and Participants With Hepatic Impairment Aged 18-75 Years of Age
The purpose of this study is to assess the effect of Hepatic impairment (HI) on the Pharmacokinetic (PK) profile and safety of Camlipixant.
- Trial name
- NCT06222892
- Testing
- Camlipixant
- Where
- 3 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bellus Health Inc. - a GSK company
Normal
Postural and Shoulder Function Norms
Musculoskeletal development during childhood is influenced by several factors, including age, body composition, and physical activity.
- Trial name
- NCT07308028
- Testing
- forward head posture angle
- Where
- Saudi Arabia
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Lincoln University College
Older Adults Institutionalized in Residential Homes
Comparing Exergaming and Usual Care Physical Therapy in Nursing Home Residents
The objective of this clinical trial is to compare the effects of exergaming and usual care physical therapy on physical function in older adults residing in nursing homes.
- Trial name
- NCT06886867
- Testing
- Exergaming, Usual physical therapy care
- Where
- 5 sites in Spain
- Volunteers
- 78 people
- Sponsor
- University of Castilla-La Mancha
Cognition Disorders in Old Age, Cognitive Function
Impact of Nutrition, Sleep, and Physical Activity on Intellectual Function and Muscle Mass in Older Adults
The goal of this prospective, single site, interventional randomized control trial is to treat age related health conditions in adults older than 65 years and functional independence.
- Conditions
- Cognition Disorders in Old Age, Cognitive Function, Frailty/Sarcopenia, MCI
- Trial name
- INSPIOR (NCT06135740)
- Testing
- Fitbit wearing, with notification for sleep, activity and nutrition based fitbit data, Routine care
- Where
- Japan
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Tokyo University
Sarcopenia
Milk and Milk-produce to Counteract the Loss of Muscle Mass and Function in Exercising Older Adults.
This project evaluates the use of different types of proteins from various food sources after an exercise session, on muscle mass and physical capacity in aged sarcopenic men (who have low muscle mass).
- Trial name
- PRO (NCT01883674)
- Testing
- Resistance training
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Anaesthesia, Postoperative Cognitive Function
Xenon Inhalation During Orthopaedic Surgery in Elderly Subjects.
The primary objective was to explore the feasibility of inhaled xenon for sedation in terms of its effect on postoperative cognitive function in elderly, in comparison with the postoperative cognitive function found after IV…
- Trial name
- NCT00192959
- Testing
- Xenon vs propofol
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Healthy Older Adults, Parkinson Disease
Brain Activity, Cognitive Function, and Walking Ability in Parkinson's Disease
The dual-task automated walking performance in people with Parkinson\'s disease (PD) is affected by their gait disturbances and impaired executive functions.
- Trial name
- NCT06588920
- Testing
- Cognitive function, gait, and electroencephalogram
- Where
- 2 sites in Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Cognitive Decline, Cognitive Symptoms
Oral Vitamin B12 Supplementation and Cognitive Performance in Elderly People
The purpose of this trial is to study the effects of oral vitamin B12 supplementation and vitamin B12 combined with folic acid supplementation on cognitive performance for 24 weeks in elderly people with mild vitamin B12…
- Trial name
- NCT00111267
- Testing
- vitamin B12 supplementation, vitamin B12 + folic acid combined supplementation
- Where
- Netherlands
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Functional Disability, Obesity
Effects of a Weight Reduction and Lifestyle Program in Older Adults
This research study will assess the effects of two different programs on weight, body composition, mobility and improved health. Measures of health will include functional abilities, and physical performance.
- Conditions
- Functional Disability, Obesity, Physical Inactivity
- Trial name
- NCT00714506
- Testing
- Diet and physical activity, Physical activity control
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Nutrition, Healthy
Improving Nutrition and Physical Activity in the Elderly Living at Home - ALAPAGE Study
CONTEXT Promoting healthy aging and preventing loss of autonomy are critical issues for many countries. In France, the 2018-2022 national health strategy emphasizes that adequate nutrition and regular physical activity are key…
- Trial name
- NCT05140330
- Testing
- ALAPAGE workshop, control workshop
- Where
- 2 sites in France
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Observatoire Regional de la Sante Provence-Alpes-Côte d'Azur
Functional Disability, Dynapenia
Multicomponent Training on Functional and Cognitive Performance of Hospitalized Older People
The goal of this clinical trial is to determine whether a multicomponent physical exercise program improves functional and cognitive capacity in hospitalized older adults compared to the usual hospital care.
- Conditions
- Functional Disability, Dynapenia, Cognitive Decline
- Trial name
- NCT06682598
- Testing
- Multicomponent physical exercise training
- Where
- Brazil
- Volunteers
- 47 people
- Sponsor
- Federal University of Rio Grande do Sul
Cerebral Small Vessel Disease, Postoperative Cognitive Function
VR Training to Improve Postoperative Cognitive Function in Elderly Patients With Cerebral Small Vessel Disease Undergoing Non-Cardiac Surgery
This clinical study aims to investigate whether virtual reality (VR)-based cognitive training can help improve postoperative cognitive function in elderly non-cardiac surgery patients with pre-existing cerebral small vessel…
- Trial name
- NCT07370844
- Testing
- Virtual reality cognitive function training, Virtual scene intervention
- Where
- 3 sites in China
- Volunteers
- 240 people
- Sponsor
- Peking University Third Hospital
Exercise Intolerance, Aging
Heat Therapy and Muscle Function Study
Exercise tolerance decreases with age and a sedentary lifestyle. Muscle critical power (CP), is a sensitive measure of exercise tolerance that is more even more relevant to and predictive of endurance performance than VO2max.
- Conditions
- Exercise Intolerance, Aging, Heat Therapy, High Intensity Interval Training
- Trial name
- NCT04733287
- Testing
- High Intensity Interval Training of the Knee Extensors, Muscle Heat Therapy, Muscle Disuse
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Brigham Young University
Cognition
The Effect of Pistachio-Rich Breakfast Meals on Cognitive Function in Healthy Older Adults
This study aims to investigate the effect of a breakfast meal containing varying serving sizes (doses) of pistachio nuts on cognitive function throughout the course of the day in healthy ageing adults aged 65-80.
- Trial name
- PACVAN (NCT06900452)
- Testing
- 0.5 serving of pistachios, 1 serving of pistachios, 2 servings of pistachios
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Reading