Clinical trials: Physical Inactivity
Low Mood, Mild Depression
Feasibility Study of an Online Physical Activity Intervention for Youth With Depression
Physical activity (PA) has recently been established as both a primary intervention for mild to moderate, and a secondary therapy for moderate to severe Major Depressive Disorder (MDD; Fortier et al., 2020).
- Conditions
- Low Mood, Mild Depression, Moderate Depression, Inactivity, Physical
- Trial name
- NCT05386745
- Testing
- physical activity
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Victoria
Muscle Atrophy, Insulin Resistance
Role of Metformin on Muscle Health of Older Adults
Muscle atrophy and insulin resistance are common after bed rest in healthy older adults. Metformin treatment has been shown to improve insulin sensitivity and attenuate muscle loss in insulin resistance adults though the…
- Trial name
- NCT03107884
- Testing
- Metformin (Bed Rest), Metformin (2 week run-in only)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Utah
Physically Inactive Hospital Employees
Financial Health Incentives to Promote Physical Activity Among Hospital Employees: A Randomized Control Trial
The objective of this randomized control trial is to examine whether incentives-for-steps (i.e. $1 per day step count goals are reached) increase daily step counts among physically inactive hospital employees.
- Trial name
- NCT02638675
- Testing
- Wellness program, Accelerometer, Incentive
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hemodynamic Instability, Pain
Evaluation in 15 Participants of Blood Flow, Comfort and Efficiency, Using 1 vs 36 Hz Stimulation Via Textile Electrodes
Muscle contractions induced by calf low-intensity neuromuscular electrical stimulation (C-LI-NMES) can increase venous return and may reduce venous thromboembolism.
- Trial name
- TTE_PVV_1_36 (NCT06082297)
- Testing
- Chattanooga Physio, DJO, neuromuscular electrical stimulation
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Physical Inactivity, Obesity, Childhood
Children With High Genetic Susceptibility Benefit More From Short-term Physical Activity Interventions
Sharp increase in childhood obesity has been regarded as one of the most serious but preventable global public health challenges.
- Trial name
- NCT06583421
- Testing
- 4-week MVPA intervention
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- China Medical University, China
Physical Inactivity, Mental Health Issue
Intervening for Increased Quality of Life Among Older People in Sweden
In the wake of the Covid-19 pandemic, Sweden and other countries have become aware of how life has changed; the world is now a "hybrid world" where many daily activities have moved online.
- Trial name
- NCT05885308
- Testing
- Otago
- Where
- Sweden
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Karlstad University
Healthy Endurance Athlet, Inactive People
Effects of Exercise Timing on Sleep Quality
Modern lifestyles are marked by a prevalence of sedentary behaviors and physical inactivity, which have been linked to numerous adverse health effects.
- Trial name
- SLEEPCORE (NCT07322276)
- Testing
- Aerobic Exercise
- Where
- France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Aging, Mental Disorder
Self-Care for Dementia Caregivers
The Self-care for Dementia Caregivers Study is a behavioral health intervention that uses digital monitoring tools and motivational health coaching to help caregivers of persons with dementia engage in a regular routine of sleep…
- Conditions
- Aging, Mental Disorder, Eating, Healthy, Physical Inactivity
- Trial name
- Care2 (NCT05309577)
- Testing
- Behavioral Self-Monitoring + Motivational Interviewing
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Office Workers, Sedanter
The Effect of Transtheoretical Model-Based Exercise Interventions on Increasing Physical Activity in Office Workers
This study aims to evaluate the effect of human and digital stimulus exercise interventions based on the transtheoretical model on increasing physical activity levels in sedentary office workers.
- Trial name
- FIT-MOS (NCT07087457)
- Testing
- The digital stimulus command, 5 day 30-minute walking program
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Gestational Diabetes, Endothelial Dysfunction
Role of ET-1, Physical Activity, and Sedentary Behavior in Microvascular Dysfunction Following GDM
Women with a history of gestational diabetes mellitus (GDM) are at a 2-fold greater risk for the development of overt cardiovascular disease (CVD) following the effected pregnancy.
- Conditions
- Gestational Diabetes, Endothelial Dysfunction, Physical Inactivity
- Trial name
- NCT06547619
- Testing
- Insulin aspart
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD
Physical Inactivity in Children
Active Transport Educational Program Based on the Ecological Model on Improving the Physical and Mental Health: MOV-ES Project
The epidemic of physical inactivity affects the entire world and is responsible for more than 5 million deaths per year. The call of the United Nations, through the 2030 Agenda and the Sustainable Development Goals, encourages…
- Trial name
- MOV-ES (NCT06357065)
- Testing
- Active transport educational program based on the ecological model
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universidad Católica del Maule
Muscular Atrophy
Effect of 14 Day Bed Rest on Health Outcomes in Young and Older Participants
This investigation aimed to compare the response of older adult and young men to 14 day bed-rest and subsequent 28 day rehabilitation.
- Trial name
- BEDREST (NCT02694471)
- Testing
- physical inactivity or bed rest with supervised recovery
- Where
- Slovenia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Physical Inactivity, Obesity, Childhood
Gamified Family-based Health Exercise Intervention to Improve Adherence to 24-h Movement Behaviors Recommendations in Children.
Physical inactivity is the fourth most important risk factor for mortality worldwide and it contributes to weight gain and obesity.
- Conditions
- Physical Inactivity, Obesity, Childhood, Sedentary Behavior
- Trial name
- Move On (NCT05741879)
- Testing
- Gamified exercise training, Standard Care
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Physical Inactivity
Efficacy of a Tailored Communication Intervention Aimed At Increasing the Number of Daily Steps
This study aims to evaluate the efficacy of a physical activity promotion intervention focused on walking behavior. The intervention is delivered via mobile application in a sample drawn from the healthy adult population.
- Trial name
- NCT05620888
- Testing
- Walk behavior change: Tailored messages (TM), Walk behavior change: Non tailored messages (NTM)
- Where
- Italy
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Physical Activity, Exercise
Smart Walk: A Culturally Tailored Smartphone-Delivered Physical Activity Intervention for African American Women
The purpose of this study is to test a culturally tailored, smartphone-delivered intervention designed to increase physical activity and reduce risk for heart disease and type 2 diabetes among African American women.
- Conditions
- Physical Activity, Exercise, Heart Diseases, Diabetes Mellitus
- Trial name
- NCT06337708
- Testing
- Smart Walk, Fitbit
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Muscle Protein Synthesis, Muscle Atrophy
Exogenous Ketosis During Bed Rest in Older Adults
The goal of this randomized, double-blind, parallel group interventional study is to evaluate the effect of ketone bodies on healthy older adults (65-85 y) during 5 days of bed rest.
- Conditions
- Muscle Protein Synthesis, Muscle Atrophy, Insulin Sensitivity, Mitochondrial Function
- Trial name
- KBR (NCT05679596)
- Testing
- ketone monoester (R)-3-hydroxybutyl (R)-3- hydroxybutyrate
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University
Physical Inactivity
Using Data-driven Insights From Wearable Technologies to Inform Whole School Physical Activity Interventions.
This is a whole-school study using co-design to inform tailored school-based interventions. Schools will be allocated either to a control or intervention group and KS2 pupils will be asked to wear a wrist-worn physical activity…
- Trial name
- NCT07050797
- Testing
- Individualised whole-school intervention, developed using data sharing and co-design.
- Where
- United Kingdom
- Volunteers
- 549 people, healthy volunteers welcome
- Sponsor
- University of Bath
Endometriosis, Physical Inactivity
Chronic Pelvic Pain in Endometriosis
Endometriosis is a chronic, inflammatory disease affecting 10% (1 out of 10) of women of reproductive age. Pelvic pain is common among women with endometriosis.
- Conditions
- Endometriosis, Physical Inactivity, Chronic Pelvic Pain Syndrome, Quality of Life
- Trial name
- NCT05863663
- Testing
- questionnaire
- Where
- Hungary
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Physical Inactivity
The Effect of a Machine Learning-Based Mobile Application on Physical Activity in Overweight and Obese Women
The goal of this clinical trial is to evaluate the effect of an algorithm-driven mobile application that provides personalized recommendations for increasing physical activity, which is an important health behavior, in the…
- Trial name
- NCT06225518
- Testing
- Individualized physical activity management system
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Physical Inactivity
Cognitive Control to Boost Physical Activity Adherence
This trial is designed to develop and test the efficacy of cognitive training strategies to improve self-regulatory capacities for middle-aged adults to adopt and sustain a physically active lifestyle.
- Trial name
- BOOST (NCT06338774)
- Testing
- Cognitive training, Exercise
- Where
- 2 sites in United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Iowa