Clinical trials: Physiologic Changes
Male Infertility, Obesity
Investigating the Physiological Effects of Weight Loss on Male Fertility
The purpose of this study is to determine the physiological effects of weight loss on seminal parameters in male participants with reduced reproductive capacity.
- Conditions
- Male Infertility, Obesity, Weight Loss
- Trial name
- NCT03553927
- Testing
- Low Energy Diet, NHS advice on healthy eating
- Where
- United Kingdom
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Body Temperature Changes, Heat Stress
Exercise Intensity and Heat Responses in Children and Youth
Little is known about how children and youth regulate body temperature during exercise in the heat compared with young adults, including whether differences in whole-body heat exchange contribute to their responses.
- Conditions
- Body Temperature Changes, Heat Stress, Child Development, Heat
- Trial name
- NCT07781592
- Testing
- Low-Intensity Exercise in the Heat, Moderate-Intensity Exercise in the Heat, Vigorous-Intensity Exercise in the Heat
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Healthy
Effects of an Acute and Chronic Training Protocol Associated to the Inter-set Velocity Loss
This study evaluates different performance, physiological and neuromuscular changes after acute and chronic resistance training intervention in physically active men.
- Trial name
- NCT03964519
- Testing
- Acute changes, Chronic changes, Familiarization
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alejandro Muñoz López
Healthy Subjects
Monitoring Changes in Physiological Parameters by Utilization of the Combined Physiological Activity Index (CPAI)
A clinical trial to validate the MCPM (Multi-parameter Combined Physiological Signal-based Monitoring), in estimating physiological activity level, at rest, previous and following stimuli.
- Trial name
- NCT03508063
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Medasense Biometrics Ltd
Dyspnea During Pregnancy, Physiological Changes in Pregnancy
Breathing Exercises Versus Incentive Spirometry in Third-Trimester Pregnancy
Shortness of breath (dyspnea) is commonly experienced during the third trimester of pregnancy due to physiological changes affecting the respiratory system.
- Conditions
- Dyspnea During Pregnancy, Physiological Changes in Pregnancy, Reduced Functional Endurance
- Trial name
- NCT07365163
- Testing
- Deep Breathing Exercises, Volume-Oriented Incentive Spirometry
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Stress
Acute Stress Recovery
The proposed study aims to evaluate whether different features of a relaxation room affect how individuals recover from acute stress.
- Trial name
- ASR (NCT05298189)
- Testing
- MindBreaks - Audio-visual, MindBreaks - Auditory-only, MindBreaks - Visual-only
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Well Living Lab, Inc.
Retinal Vascular
Physiologic Changes of Posterior Ocular Segment During the Menstrual Cycle
Changes of luteinizing hormone (LH), estrogen and progesterone during the menstrual cycle influence the ocular physiology in both anterior and posterior segments.
- Trial name
- NCT04731207
- Testing
- Optovue®
- Where
- Thailand
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Hyperthermia
Physiological and Thermoregulatory Responses of Body Cooling During Cycling in a Hot Environment
BHSAI is developing a computational system that provides early alerts of a rise in core body temperature to help reduce the risk of heat injury in the field and during training.
- Trial name
- PYTHON (NCT04715711)
- Testing
- Forearm coolng, Wet-towel cooling, mist-fan
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Water Sports
Physiological Variables and Rowing Performance.
The purpose of this study is to investigate the association between the changes in physiological variables based on fitness testing and the changes in rowing performance.
- Trial name
- NCT04596111
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Franklin Pierce University
Prostate Cancer, Hypothermia
MRI Temperature Mapping of the Prostate and Urogenital Pelvis Cooled by an Endorectal Balloon
Urinary incontinence and sexual dysfunction are potential side effects for men undergoing the successful removal of the cancerous prostate via surgery.
- Conditions
- Prostate Cancer, Hypothermia, Urinary Incontinence, Erectile Dysfunction
- Trial name
- NCT01979848
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Physical Activity, Blood Pressure
Effect of Mat Pilates Training on Women After Menopause
This project aims to verify the chronic effect of Mat Pilates exercise on climacteric symptoms, ambulatory blood pressure responses, lipid and glucose profile and pro and anti-inflammatory and antioxidant markers in…
- Trial name
- NCT03626792
- Testing
- Hypertensive group, Normotensive group
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Infant, Newborn, Weight Loss
Effect of Kangaroo Care on Phyiological Weight Loss in Term Newborns
The aim of the study is to evaluate the effect of kangaroo care on physiological weight loss in term newborns.
- Trial name
- NCT05001334
- Testing
- Kangaroo care training
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Retinal Vascular
Physiologic Change of Posterior Ocular Segment During Pregnancy
Women's physiology changes markedly during normal pregnancy. The most distinct alterations occur in the hormonal and cardiovascular systems. There is a dramatic increase in both estrogen and progesterone.
- Trial name
- NCT04731415
- Testing
- Optical coherence tomography and optical coherence tomography angiography (Optovue®)
- Where
- Thailand
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Delayed-onset Muscle Soreness
Vibration Rolling, Non- Vibration Rolling,and Static Stretching for Delayed-onset Muscle Soreness
Delayed-onset muscle soreness (DOMS) is an acute micro-trauma or inflammatory response experienced in the most runners; and, it concurrently impairs athletic performance and may increase the risk of sports injury.
- Trial name
- NCT03986242
- Testing
- rolling, Vibration rolling, static stretching
- Where
- Taiwan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Healthy
Structure and Function of the Human Tongue
This study will use magnetic resonance imaging (MRI) and ultrasound to examine changes in tongue volume and blood circulation during tongue exercises that require the use of different tongue muscle movements and contractions.
- Trial name
- NCT00007137
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Fertility Disorders, Hypothalamic Dysfunction
Reproductive Hormones During Sustained Administration of Kisspeptin
We want to find out what happens to reproductive hormone levels; Luteinising Hormone (LH), Follicle Stimulating Hormone (FSH), testosterone and oestradiol when kisspeptin is administered to people for a period of 8 days each…
- Trial name
- KisspeptPump (NCT02081924)
- Testing
- Kisspeptin 0.1, Saline, Kisspeptin 0.3
- Where
- United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Physiological Stress, Cognitive Change
Effects of Prebiotics on Cognition and Health
This research intervention aims to examine the effects of prebiotic consumption on changes in behavioral and biological measures of cognition and stress among adults.
- Conditions
- Physiological Stress, Cognitive Change, Gastrointestinal Health
- Trial name
- EPOCH-2 (NCT04551937)
- Testing
- Lactose Free 1% Milk, Lactose Free 1% Milk + 10 g prebiotic
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Physiologic Changes, Exercise
Chrysin Exercise Performance Pilot Study
This single-arm pilot study evaluates within-subject changes in aerobic capacity, heart rate responses, cycling power output, and related physiological measures in healthy adults during and after 30 days of supplementation with a…
- Conditions
- Physiologic Changes, Exercise, Physiological Changes (Heart Rate)
- Trial name
- NCT07872111
- Testing
- Chrysin LipoMicel
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Isura
Healthy Ageing
Vasopressin in the Elderly: Physiological Changes in Neuroendocrine Function and Urinary Secretion in Healthy Aging
Elderly people are at a high risk for disturbances in water homeostasis, with both hypo- and hypernatremia being more common with increasing age.
- Trial name
- VENUS (NCT06930300)
- Testing
- Hypertonic 3% saline, Water
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Participants of the Be-MaGIC-Study 2009
Prospective Follow-up, Marathon, Long Term, Inflammation and Cardiovascular System
Pro-MagIC is a prospective observational study and includes participants of the Be-MaGIC-Study 2009 (n=277/NCT00933218). We aim to detect exercise-induced physiological changes (inter alia of the cardiovascular system) induced by…
- Trial name
- Pro-MagIC (NCT04166903)
- Where
- Germany
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich