Clinical trials: Physiological Responses
Physiological Responses
The Role of TRP Channels in DPN
The study aims to characterize the vascular response upon topical application of cinnamaldehyde, allyl isothiocyanate and capsaicin on feet skin in healthy volunteers.
- Trial name
- NCT07237022
- Testing
- Cinnamaldehyde, Allyl isothiocyanate (AITC), Capsaicin
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Other Conditions That May Be A Focus of Clinical Attention
Chronic Sleep Restriction
Sleep is a physiological state considered essential for health and human survival. The prevalence of chronic sleep restriction has increased in modern society, as well as the effects of the same health concerns about various…
- Trial name
- CSR (NCT01493661)
- Testing
- Chronic Sleep Restriction
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Obesity, Sweeteners
Mapping the 'Sweet Brain' in Healthy Participants
The human brain has a central role in regulating appetite and food intake. It integrates many metabolic, hedonic and trait-related signals that affect eating behaviour and determine when and how much we eat.
- Trial name
- NCT04162457
- Testing
- Stevia, Glucose, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Sleep Deprivation
Combined Effects of Acute Sleep Restriction and Moderate Acceleration (+Gz) on Physiological and Behavioral Responses to High Mental Workload
Fighter pilots have to perform tasks requiring high mental workload during moderate-intensity acceleration phases (2 to 3G) that can last several minutes.
- Trial name
- CogPhyAero (NCT06017882)
- Testing
- Partial sleep deprivation
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Healthy
Physiological Response to 5 Days Fasting
To investigate energy metabolism, anthropometry, blood pressure, gut microbiome, serum metabolome, glucose variability and neural mechanisms of food choice and mood before and after 5 days of fasting as well as their persistence…
- Trial name
- NCT04452916
- Testing
- Buchinger fasting
- Where
- Germany
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Heat Strain, Healthy Volunteer Study
The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response
The goal of this clinical trial is to learn about the processes occurring in the kidneys while under heat stress in healthy volunteers.
- Conditions
- Heat Strain, Healthy Volunteer Study, Kidney Dysfunction
- Trial name
- NCT06983730
- Testing
- Vitamin B3
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Physiological Stress
Impact of Breathing Interventions on Stress Markers
The goal of this clinical trial is to examine the effects of slow breathing breathing on markers of stress in healthy college aged individuals.
- Trial name
- NCT05825846
- Testing
- Virtual- reality active shooter drill
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Texas State University
Self Perception
Perception of Nonverbal Acoustic Signals and Resulting Physiological Responses (SINOVE-PER)
Like many other animals, humans produce nonverbal signals including screams, grunts, roars, cries and laughter across a variety of contexts.Due to their acoustic structure, nonverbal vocalizations and valanced speech (e.g.…
- Trial name
- SINOVE-PER (NCT05252312)
- Testing
- Psycho-acoustic tests
- Where
- France
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Exercise, Cardiovascular Function, Fatigue, Muscular Power
Physiological Responses to Maximal 4-s Sprint Interval Cycling
The optimal recovery duration depends on the intensity of exercise and in the present study the intensity was maximal power for 4-s while cycling an 'Inertial Load' ergometer (ILE).
- Trial name
- NCT04448925
- Testing
- inertial-load exercise (ILE)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Depression
Physiologic Monitoring of Antidepressant Treatment Response
Study Objectives: to identify neurophysiologic effects of venlafaxine treatment in normal controls using quantitative EEG (QEEG) cordance to examine the effects of venlafaxine on different rating scales measuring mood and anxiety…
- Trial name
- Ven Nls I (NCT00759317)
- Testing
- venlafaxine (Effexor)
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Autonomic Nervous System Function, Psychophysiological Regulation
Effects of Brief Heart Rate Variability Biofeedback on Physiological and Emotional Responses
This completed randomized laboratory study investigated the immediate effects of a single 10-minute session of heart rate variability biofeedback (HRV-B) on cardiac activity, forehead physiological signals, and emotional…
- Trial name
- NCT07911215
- Testing
- Psychoeducational Video Viewing, Heart Rate Variability Biofeedback
- Where
- Israel
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Personalized Nutrition
N=1 Trials of Individual Variability in Post-prandial Glycemic Responses to Diets of Varying Macronutrient Composition
The key objective of this study is to identify the most suitable diet (i.e. high protein, high fat, low GI, high GI) for an individual.
- Trial name
- NCT05402085
- Testing
- High Protein Diet, High Fat Diet, High Carbohydrate-Low Glycemic Index Diet
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Anxiety
Disentangling Anxiety Sensitivity and Anxiety-induced Physiological Stress Response
The proposed study aims to investigate experimentally anxiety sensitivity and physiologic sensations associated with anxiety using a paradigm combining hydrocortisone, caffeine, and a set of social stress challenges.
- Trial name
- NCT02372110
- Testing
- HPA, ANS stimulation
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Emotional, Affective, and Physiological Responses to Audiovisual Artworks Inspired by Climate-Related Environmental Changes in Nunavik
Emotional and Affective Responses to Music Inspired by Permafrost Thaw in Nunavik
This study will compare how young adults respond to four audiovisual artworks inspired by ice melt and permafrost thaw in Nunavik, northern Quebec. Permafrost is ground that remains frozen for at least two consecutive years.
- Trial name
- NCT07915089
- Testing
- Viewing Four Audiovisual Artworks Inspired by Environmental Changes in Nunavik
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre integre universitaire de sante et de services sociaux du Centre-Sud-de-l'Île-de-Montréal
Emotions
Questionnaire and Projective Color Association in Physiological Responses to Different Emotional Charge
A sample of 101 individuals will be used for this purpose, where each of them will be exposed to 145 different stimuli. Comparison of their physiological responses to stimuli (cerebral blood flow, electrical activity of the…
- Trial name
- PARC (NCT05363852)
- Testing
- Standard set of visual word and picture stimuli
- Where
- Czechia
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Ostrava
Physiological Responses, Pilates Exercise
Effect of Muscle Strengthening Training with Pilates Reformer on Overweight/obese and Normal Body Weight Women (PRET)
This study investigates the physiological responses and the metabolic burden of a Pilates Reformer strength training session in physically inactive premenopausal women with a body mass index of 18-24.9 and 25.01-39.9.
- Conditions
- Physiological Responses, Pilates Exercise, Overweight and Obese Women, Energy Expenditure
- Trial name
- PRET (NCT06675162)
- Testing
- Pilates Reformer Training
- Where
- 2 sites in Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Bariatric Surgery
Physiological Responses to Laparoscopic Sleeve Gastrectomy: Focusing on Ghrelin
Our hypothesis is that decreased concentration of ghrelin after LSG is important for the decreased appetite and food intake postoperatively.
- Trial name
- NCT04055025
- Testing
- Ghrelin
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Functional Dyspepsia
Physiological Response and Visual Attention to Visual Food Images in Healthy Subjects and in Functional Dyspepsia Patients
In functional dyspepsia (FD), abnormal cognitive and emotional changes such increased sensitization, anxiety, and depression scores have been reported in addition to the peripheral changes in gastrointestinal tract functions.
- Trial name
- NCT02727556
- Testing
- visual images
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Healthy
Physiological Response to Salbutamol and Exercise
The scope of the study is to investigate the physiological response to salbutamol and exercise. A particular focus is on the metabolic response and amine metabolism.
- Trial name
- NCT03902106
- Testing
- salbutamol, exercise
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Stress
Psychophysiological Stress Response in Medical Students During Simulation-Based Communication Training -Study Protocol
In this study, researchers will examine key predictors of stress reactions in medical students participating in simulation-based communication training.
- Trial name
- SIMU2025 (NCT06906614)
- Testing
- Simulation-Based Communication Training
- Where
- Czechia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Masaryk University