Clinical trials: Physiological Responses
Autism Disorder
Triadic Interactions of Families With Autism and Oxytocin
The study will investigate the effects of an intranasal administration of oxytocin (OT) to parents of children with autism spectrum disorders (ASD) on the quality of mother-father-child interactions.
- Trial name
- TAO (NCT01912378)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy Participants
"Physiological Responses to Manual Pressure in Healthy Adults"
This randomized experimental study will investigate how different intensities and application patterns of manual pressure applied to the upper trapezius muscle affect physiological responses in healthy adults.
- Trial name
- VALIRAT1 (NCT07393815)
- Testing
- "Manual Pressure Protocol", Manual Therapy Protocols (DLM, light and moderate-pressure massage), Graded Sustained Pressure
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Surgical Stress Response, Stress Physiological
Feasibility of Breathwork Intervention With Older Adults After Knee Surgery
Postoperative complications after surgical procedures, including following total knee arthroplasty (TKA), have a negative impact on the health and well-being of surgical patients.
- Conditions
- Surgical Stress Response, Stress Physiological, Stress Physiology, Stress Psychological
- Trial name
- NCT07464860
- Testing
- A 5-minute Asynchronous Breathwork Intervention, A 5-minute Asynchronous Card Game Video
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Stress, Stress, Physiological
The Effect of Progressive Relaxation and Breathing Exercises Accompanied by Music on the Stress Levels of Nursing Students and Their Bio-psycho-social Responses
This clinical study will be conducted to determine the effects of musically accompanied progressive muscle relaxation and deep breathing exercises on nursing students' stress levels and bio-psycho-social responses to stress.
- Trial name
- NCT06008236
- Testing
- Progressive Muscle Relaxation and Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Hyperthermia
Physiological and Thermoregulatory Responses of Body Cooling During Cycling in a Hot Environment
BHSAI is developing a computational system that provides early alerts of a rise in core body temperature to help reduce the risk of heat injury in the field and during training.
- Trial name
- PYTHON (NCT04715711)
- Testing
- Forearm coolng, Wet-towel cooling, mist-fan
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Athletic Performance
Effects of High-Intensity Interval Training (HIIT) on Physiological Responses in Alpine Skiers
The aim of this study was to investigate the effects of high-intensity interval training (HIIT) on anaerobic performance and cardiorespiratory responses in alpine skiing athletes.
- Trial name
- HIIT-ALP (NCT07904481)
- Testing
- High-Intensity Interval Training (HIIT), Regular Alpine Skiing and Strength Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TUNC ILCIN
Hydration, Dehydration
The Effect of Proprietary Water on Physiological and Perceptual Responses
The purpose of this study is to determine if drinking proprietary water (PW) during a standardized daily plan as compared to distilled water (control) and carbohydrate-electrolyte (CE) drink can improve hydration status over…
- Trial name
- NCT05451446
- Testing
- proprietary water, Active comparator
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Premature Ejaculation, Sexual Dysfunction
Brain Networks Implicated in Lifelong Premature Ejaculation Patients
Using Brain Mapping and Cognitive ERPs, the investigatos have searched for a Brain Networks involved during Inhibitory Control in Lifelong Premature Ejaculation (LPE) participants.
- Trial name
- LPE (NCT04850703)
- Testing
- Transcranial Radom Noise Stimulation, Take Dapoxetine, Compare LPE EEG endophenotype between participants and healthy controls
- Where
- Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Moises Domingo
Anesthesia, Stress, Physiological
Adductor Canal Block Versus Patient Controlled Analgesia, in the Surgical Stress Response for Anterior Cruciate Ligament Repair
To evaluate the surgical stress response in anterior cruciate ligament repair with an adductor canal block versus patient controlled endovenous analgesia.
- Conditions
- Anesthesia, Stress, Physiological, Surgery
- Trial name
- NCT04797546
- Testing
- Adductor Canal Block, Morphine Patient Controlled Analgesia
- Where
- Chile
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Pain Response, Stress, Trauma
Characterizing Subjective and Physiological Responses to Stress and Pain and Cognitive Learning and Executive Function
The study design is to assess the between groups factor (controls, chronic pain, addicted individuals) and repeated measures factor of pain/stress (pain vs no pain) along with a longitudinal component to assess stress, pain and…
- Trial name
- NCT04419831
- Testing
- Yale Stress Pain Test (YSPT)
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Yale University
Intubation Complication, Cardiovascular Morbidity
The Effects of Lidocaine and Magnesium Sulphate on the Attenuation of the Hemodynamic Response to Tracheal Intubation
Justification and Objectives: The hemodynamic response to stimuli of the airways is a common phenomenon and its control is important to decrease systemic repercussions.
- Trial name
- NCT02359370
- Testing
- Lidocaine, Magnesium Sulphate
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Hospital de Base
Obesity
GLP-1 Response and Effect in Individuals With Obesity Causing Genetic Mutations
The obesity epidemic is attributable to dietary and behavioral trends acting on a person's genetic makeup to determine body mass and susceptibility to obesity-related diseases.
- Trial name
- NCT02082496
- Testing
- Liraglutide
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Stress, Physiological, Stress, Psychological
A Comparison of Acute Psychobiological Responses to Laboratory Stress Tests
The Mannheim Multicomponent Stress Test (MMST) is a validated laboratory stress test that combines cognitive, emotional, acoustic and motivational stress components.
- Trial name
- NCT06066320
- Testing
- MMST, TSST
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Healthy
Effect of Prolonged Military Exercises With High Load Carriage, on Neuromuscular Fatigue and Physiological/Biomechanical Responses
Land military missions generally combine prolonged walking/moderate-pace-running and other physical actions such as creeping, jumping, shooting,… which are associated with the direct carrying of high to severe loads of equipment…
- Trial name
- NCT01127191
- Testing
- military equipment
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Transmission, Patient-Professional
The Effects of Filter During CPET on WOB and Aerosol Particle Concentrations
Due to the concerns of virus transmission during COVID-19 pandemic, multiple respiratory societies postpone or limit pulmonary function test, especially cardiopulmonary exercise test (CPET), as patients may generate large amount…
- Trial name
- NCT04526925
- Testing
- Respiratory filter in-line placed with the standard mouthpiece, Standard mouthpiece
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Physiological Responses, Behavior
Behavioural and Physiological Responses to Dog Visits in Nursing Homes
In brief the study aims to investigate how nursing home residents receiving dog visits respond to contact with the dog, by comparing visits with and without a dog present.
- Conditions
- Physiological Responses, Behavior, Mood
- Trial name
- NCT05516264
- Testing
- Dog visits/control visits, Control visits/dog visits
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Anxiety Wounds and Injuries
Healing Through Play
Wound dressing is a common procedure for children with injuries or wounds. The procedure can cause pain, fear, and anxiety. Children may also experience changes in heart rate and breathing when they feel distressed.
- Trial name
- Healing (NCT07909798)
- Testing
- Usual Care
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Zaytoonah University of Jordan
Overweight, Obesity
Sprint to Fitness: Effect of Outcome Expectations on Responses to Interval Exercise Training
The purpose of this study is to research the effects of exercising at high intensities for short periods of time on exercise tolerance and motivation.
- Trial name
- NCT03162978
- Testing
- HIIT + POE, HIIT only
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Stress (Psychology), Stress
Impact of OnabotulinumtoxinA (BOTOX®) on Stress
The purpose of this prospective single-center, blinded*, randomized, proof-of-concept study is to determine whether OnabotulinumtoxinA (BOTOX®) injections will change the level of stress perceived by generally healthy adult…
- Conditions
- Stress (Psychology), Stress, Healthy Adult Female Participants, Stress, Psychologic
- Trial name
- NCT06778421
- Testing
- Intramuscular injection, OnabotulinumtoxinA (Botox®) Injections, Sodium Chloride
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Center for Advanced Facial Plastic Surgery
Irritable Bowel Syndrome
Identification of IBS Metabotypes Based on Physiological Responses to Food
Irritable bowel syndrome (IBS) is a condition characterized by abdominal pain, bloating, constipation, diarrhea and gas and affects up to 15% of the Western population.
- Trial name
- NCT03653689
- Testing
- FODMAP, Gluten
- Where
- Sweden
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Uppsala University