Clinical trials: Physiological Responses
Climate Change Heat Stress
Assessment of Climate Change Related Heat Stress Among Workers in Upper Egypt : Impact of Intervention Program on Physiological Responses
Climate change has a significant impact on human health and productivity at work. According to the Intergovernmental Panel on Climate Change (IPCC) and the United Nations, climate change is one of the most significant global…
- Trial name
- NCT07538778
- Testing
- Heat Stress Awareness Program (HSAP), no traing
- Volunteers
- 84 people
- Sponsor
- Assiut University
Stress, Psychological, Stress, Emotional
Online Emotional Response to Completing a Childhood Maltreatment Self-report Scale
Childhood adversity in the form of maltreatment and household dysfunction is the most important risk factor for psychopathology as well as a major risk factor for a host of medical disorders.
- Trial name
- MACEStress (NCT06152549)
- Testing
- Maltreatment and Abuse Chronology of Exposure Scale as a stress challenge, Standardized Maths and Verbal Questions such as the ones used in SATs, Chronology of Perceived Discrimination Scale (CPDS)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Autonomous Nervous System, Fatigue
Exploring Physiological Responses of Virtual Reality Walking Exercise Versus Treadmill Walking in Healthy Individuals
This study aimed to systematically compare the physiological responses generated by walking exercises conducted in a VR environment versus those performed on a treadmill, with a specific focus on their impacts on the autonomic…
- Trial name
- NCT06679348
- Testing
- walking exercise on treadmill, Treadmill walking exercise using VR
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Atlas University
Critical Illness, Critically Ill Patients
Physiological Changes in Adult Intensive Care Patients Following Contact With Their Primary Caregiver
Patients admitted to intensive care units are exposed to multiple environmental and clinical factors that may affect their physiological responses.
- Trial name
- CARE-ICU (NCT07761364)
- Testing
- Standardized therapeutic physical contact
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Universidad Autonoma del Estado de Mexico
Interventional Study
Physiological Responses in Robotic Neurorehabilitation
Robotic rehabilitation is very useful for improving functional recovery in neurological patients, there is not much evidence on its role in improving physiological responses (i.e.
- Trial name
- Lokophysio (NCT04035122)
- Testing
- Robotic Treatment, Conventional Treatment
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Subacute Stroke
Efficacy of Unilateral Versus Bilateral Approach to Robot-Assisted Rehabilitation in Patients With Subacute Stroke
Robot-assisted training (RT) devices developed to date have a significant impact on stroke rehabilitation. Several research groups have developed the robotic devices and examined their efficacy on improving UL function after…
- Trial name
- NCT01939041
- Testing
- InMotion3 (IMT), Bi-Manu-Track (BMT), Control intervention (CI)
- Where
- Taiwan
- Sponsor
- Chang Gung Memorial Hospital
Multiple Sclerosis, Mood Disorders
Study of Brain Activations and Physiological Responses Using NeuroBiofeedback in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) characterized by inflammation, demyelination, gliosis, and neuronal loss.
- Conditions
- Multiple Sclerosis, Mood Disorders, Cognitive Impairment
- Trial name
- NBF2023 (NCT06239090)
- Testing
- Rehacor-T
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Polycystic Ovary Syndrome
The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor Agonists
Background: Brown adipose tissue (BAT) is a type of fat in the body. It may prevent weight gain, improve insulin sensitivity, and reduce fatty liver. Researchers want to see if BAT helps the body burn energy.
- Trial name
- NCT03049462
- Testing
- Mirabegron, B Complex Plus Vitamin C Tablets
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Dyspareunia (Female)
Rigid Hymenal Ring as a Cause for Insertional Dyspareunia
Given the frequently observed rigid hymenal ring as a cause of insertional dyspareunia as well as the resolution of pain (including posterior vestibulodynia) following its targeted therapy, the study aims to describe its…
- Trial name
- NCT07913386
- Testing
- Hymenectomy
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Hadassah Medical Organization
Healthy
Training Study to Characterize Biomarkers to Chickenpox and Yellow Fever Vaccines
It is thought that vaccines trigger innate inflammatory responses to induce antigenspecific adaptive immunity (the desired effect), but excessive inflammation may lead to serious inflammatory complications or unwanted side…
- Trial name
- NCT01765413
- Testing
- Varicella-zoster virus, Yellow Fever Vaccine
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Disorders of Consciousness
Tickle Stimulation in Disorders of Consciousness (DoC)
The aim of this project is to investigate whether tickling stimulations can have a short-term effect on the responsiveness of patients with Disorders of Consciousness due to Severe Acquired Brain Injury and to compare this effect…
- Trial name
- TICKLING-DOC (NCT06922162)
- Testing
- Tickle stimulation, Neurophysiological Monitoring with SedLine
- Where
- 2 sites in Belgium, Italy
- Volunteers
- 16 people
- Sponsor
- Anna Estraneo
Preterm Neonates, Heel Lance Procedures
Crochet Octopus in Reducing Procedural Pain During Heel Lance in Preterm Neonates
Neonates, particularly those hospitalized in neonatal intensive care units (NICUs), are subjected to numerous painful procedures essential for their diagnosis and monitoring.
- Conditions
- Preterm Neonates, Heel Lance Procedures, Procedural Pain
- Trial name
- RCT (NCT07828795)
- Testing
- Crochet Octopus
- Volunteers
- 98 people
- Sponsor
- Mansoura University
Obesity, Morbid, Bariatric Surgery
Physiological Effects of Gastric Sleeve Operation
After gastric sleeve patients undergo a substantial weight loss, but the physiological mechanisms behind the weight loss is not fully elucidated.
- Trial name
- NCT03046186
- Testing
- Mixed meal test with double tracer technique
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Healthy
The Immediate Physiological and Perceptual Response to Blood-flow Restricted Strength Training With Eccentric Loading
Decreasing workloads in strength training makes it more tolerable for a broad range of people. When designed as blood-flow restriction training, similar gains in strength and muscle mass are achieved compared to traditional…
- Trial name
- E-BFR (NCT06856629)
- Testing
- Eccentric blood-flow restriction training, Eccentric free-flow training
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dario Kohlbrenner
Hepatocellular Carcinoma, Fibrolamellar Hepatocellular Carcinoma
Study of Sunitinib in Patients With Advanced/Inoperable Fibrolamellar Carcinoma
The purpose of this study is to evaluate the antitumor activity of sunitinib in patients with advanced/inoperable fibrolamellar hepatocellular carcinoma.
- Trial name
- Fibrolam (NCT01215565)
- Testing
- Sutent
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Systemic Inflammatory Response Syndrome
INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery
The aim of the study is to evaluate a clinically and economically most effective diagnostic algorithm for prediction of inflammatory response related complications in patients undergoing heart surgery with use of cardiopulmonary…
- Trial name
- INFLACOR (NCT01020409)
- Testing
- cardiac surgery with CPB use
- Where
- Poland
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Stress Psychological, Stress Physiological
Relaxation-Response-based Mental Health Promotion - Open and Calm 2013
The purpose of the study is to investigate health-promoting and stress-reducing psychological, physiological and hormonal effects of a 9-week meditation-based course in personal health and to examine potential baseline factors…
- Conditions
- Stress Psychological, Stress Physiological, Quality of Life
- Trial name
- RR-MHP OC13 (NCT02140307)
- Testing
- Relaxation Response-based Mental Health Promotion (RR-MHP)
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Steen G Hasselbalch
Pain, Stress
Study of Spirit Pass in Newborn and Patient
Stress is a multiple variable and an inevitable aspect of life. Any change that affects the life of a person is a stressful agent, being possible to widely vary its nature and may be formed by several components, since…
- Trial name
- SSPNP (NCT02489136)
- Testing
- laying of hands (Spiritist "passe")
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Triangulo Mineiro
Hypoglycemia, Physiological Stress
The Functional Neuroanatomy of the Human Physiological Stress Response
The purpose of this study is to examine the effect of a moderately low blood sugar stress on the nervous system. The investigators hope that information obtained from completing this study will help to reveal information about…
- Trial name
- Hypo fMRI (NCT03867344)
- Testing
- Hypoglycemic Hyperinsulinemic Clamp, Normoglycemic Hyperinsulinemic Clamp
- Where
- 2 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obesity
Oro-gastro-intestinal Digestion of Emulsified Fat
Interaction of fat with the mouth, stomach and intestine will trigger physiological responses that will impact on the digestion, gut transit time and absorption of fat.
- Trial name
- NCT01478750
- Testing
- administration of fat (sunflower oil), emulsified, Insertion of nasoduodenal tube
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center