Clinical trials: Placenta
Covid19, Pregnancy Related
Safety, Testing/Transmission, and Outcomes in Pregnancies With COVID-19
Pregnant women are a vulnerable and high-risk population, as COVID-19 is associated with an increased risk preterm birth, cesarean section, and maternal critical care.
- Conditions
- Covid19, Pregnancy Related, Maternal Complication of Pregnancy, Coronavirus
- Trial name
- STOPCOVID19 (NCT04718220)
- Testing
- Antibody testing for SARS-CoV-2 IgG, Testing for SARS-CoV-2 RNA, Testing for SARS-CoV-2 IgM/IgG
- Where
- United States
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Placental Insufficiency Hypertensive Disorders of Pregnancy Diabetes Mellitus in Pregnancy Thrombophilia in Pregnancy Adverse Perinatal Outcomes
Fetus Programming and Long Active Outcomes, Interaction Between Mother, Placenta and Fetus in Perinatal and Methabolic Disbalansces-focusing Diabetic Pregnancies
The placenta is a temporary but essential organ that develops during pregnancy and supports the growth and survival of the fetus.
- Trial name
- NCT07337759
- Testing
- No intervention (observational study)
- Where
- Serbia
- Volunteers
- 440 people
- Sponsor
- University of Belgrade
Premature Birth
Placental and Cord Blood Markers Associated With Premature Birth and Disorders of Premature Birth in Newborn Infants
The purpose of this study is to determine if changes in specific gene products in the placenta or cord/infant blood affect a baby's birth weight, increase the risk of premature birth, or increase the risk of developing diseases…
- Trial name
- NCT01439048
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Postpartum Women
Influence of Acupuncture in the Postpartum Blood Loss
In this study, a single blind randomized trial with third party evaluation is carried out in order to compare the postpartum blood loss when Ren Mai 6 point is stimulated and when this point is not stimulated.
- Trial name
- NCT02539121
- Testing
- Acupuncture
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Principe de Asturias
Miscarriage
Could Colour Dopper Improve the Diagnosis of Retained Placental Fragments After Second Trimester Miscarriage ?
Value of pelvi- abdominal ultrasound and Doppler in diagnosis of retained products of conception after second trimester miscarriage to select who will benefit from surgical evacuations or conservative management.
- Trial name
- NCT02419300
- Testing
- ultrasoungraphy
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Ain Shams University
Placenta Previa
Combined Bilateral Uterine Artery Ligation and Bakri Balloon During Cesarean Section
This study will be performed to compare the effectiveness of routine Bakri balloon tamponade and Bilateral Uterine Artery Ligation during cesarean section in patients with placenta previa
- Trial name
- NCT04518150
- Testing
- Bakri balloon, Bilateral Uterine Artery Ligation
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Aswan University Hospital
Placenta Percreta, Bladder Injury
Bladder Suture in Uterus-Sparing Surgery and Hysterectomy for Placenta Percreta
This study aimed to evaluate the short-term and long-term complications of placenta percreta with bladder invasion. This evaluation focuses on cases where bladder dissection and ACAR-style bladder sutures were applied in cases of…
- Conditions
- Placenta Percreta, Bladder Injury, Sutures
- Trial name
- NCT06267599
- Testing
- ACAR-Style Bladder Suture
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Necmettin Erbakan University
Placenta Accreta
Peripartum Cesarean Hysterectomy for Placenta Percreta
The aim of this study is to address the possible preoperative determinants of extrauterine diseases in cases of placenta previa percreta and to compare the operative and postoperative characteristics of cases with and without…
- Trial name
- NCT05979181
- Testing
- Cesarean hysterectomy
- Where
- Egypt
- Volunteers
- 73 people
- Sponsor
- Mansoura University
Cerebral Palsy
Safety of Cultured Umbilical or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for CP
This trial will study the safety and efficacy of intravenous infusion of cultured umbilical or placental derived mesenchymal stem cells for the treatment of Cerebral Palsy
- Trial name
- NCT05018871
- Testing
- Umbilical or placental derived mesenchymal stem cells
- Where
- 2 sites in United States, Greece
- Volunteers
- 15 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Pre-Eclampsia, Fetal Growth Retardation
Doppler and Biological Second Trimester Placental Insufficiency Screening
To assess the role of uterine artery and maternal serum leptin and lipids and their combination in screening for pre-eclampsia and small-for-gestational-age (SGA) fetuses at 20-24 weeks of gestation
- Conditions
- Pre-Eclampsia, Fetal Growth Retardation, Placental Insufficiency
- Trial name
- ARTULEP (NCT00465634)
- Where
- France
- Volunteers
- 235 people
- Sponsor
- University Hospital, Tours
Placenta Previa
Blood Loss During Cesarean Delivery in Placenta Previa Patients
To compare the efficacy and safety profile of intravenous tranexamic acid versus intrauterine misoprostol in reducing the blood loss during and after cesarean delivery in pregnant women diagnosed with placenta previa
- Trial name
- NCT05340205
- Testing
- Tranexamic acid, Misoprostol, Oxytocin
- Where
- Egypt
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cesarian Section, Neonatal and Perinatal Conditions
Transplacental Neonatal Transfer of Lidocaine During Urgent Caesarean Delivery
Lidocaine is commonly administered through an existing labor epidural catheter to provide surgical anesthesia for urgent cesarean delivery.
- Conditions
- Cesarian Section, Neonatal and Perinatal Conditions, Epidural Anesthesia, Lidocaine Toxicity
- Trial name
- Lidocaine TNT (NCT07826468)
- Testing
- Category Lucas 1 cesarian section, Category 3 Lucas Cesarian section
- Where
- France
- Volunteers
- 95 people
- Sponsor
- Hôpital de la Croix-Rousse
Cesarean Section Complications
Reducing Blood Loss During Cesarean Hysterectomy for Placenta Accreta Spectrum
PAS is an obstetrics condition that is closely linked with massive obstetrical hemorrhage with a varied incidence about once in every 533 live births.
- Trial name
- NCT03570710
- Testing
- intravenous tranexamic acid, Topical tranexamic acid, Normal saline
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Aswan University Hospital
Pregnancy Complications, IVF
The START Clinic: a Feasibility Study
This is a study of the feasibility of a translational research clinic for pregnancies conceived by in vitro fertilisation (IVF).
- Conditions
- Pregnancy Complications, IVF, Fetal Growth Retardation, Preeclampsia
- Trial name
- START (NCT04488861)
- Testing
- Non-interventional cohort study
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Manchester Academic Health Science Centre
Wound Heal
A Retrospective, Observational Study of the Real-world Safety and Performance of InnovaMatrix® AC at a Single Centre
The use of a decellularised porcine placental extracellular matrix in hard-to-heal wounds: A retrospective study of the real-world performance of InnovaMatrix® AC at a single centre.
- Trial name
- NCT07170566
- Testing
- innovaMatrix AC
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- ConvaTec Inc.
Mucopolysaccharidosis I, Mucopolysaccharidosis VI
Human Placental-Derived Stem Cell Transplantation
The purpose of this clinical trial is to investigate the safety of human placental-derived stem cells (HPDSC) given in conjunction with umbilical cord blood (UCB) stem cells in patients with various malignant or nonmalignant…
- Conditions
- Mucopolysaccharidosis I, Mucopolysaccharidosis VI, Adrenoleukodystrophy, Niemann-Pick Disease
- Trial name
- HPDSC (NCT01586455)
- Testing
- Human Placental Derived Stem Cell
- Where
- 3 sites in United States
- Volunteers
- 43 people
- Sponsor
- New York Medical College
Malaria, Malaria in Pregnancy
A Randomized Controlled Trial for Intermittent Preventive Treatment in Pregnancy With Fansidar in Solomon Islands
The purpose of this study is to assess the effectiveness of intermittent preventive treatment in pregnancy (IPTp) with Sulphadoxine-pyrimethamine compared to chloroquine prophylaxis in Honiara, Solomon Islands for prevention of…
- Trial name
- IPTpRCT (NCT00964691)
- Testing
- Sulphadoxine-pyrimethamine, Chloroquine prophylaxis
- Where
- Solomon Islands
- Volunteers
- 2,504 people, healthy volunteers welcome
- Sponsor
- Ministry of Health and Medical Services, Solomon Islands
Placenta Previa Total, Nursing Role
Effects of Peri Partum Integrated Nursing Care Versus Routine Care in Placenta Previa : A Randomized Controlled Trail
At our institution, the annual number of placenta previa was 494 cases (1.7%); of whom 95 cases (19.2%) were proved to have a placenta accreta.
- Trial name
- NCT04274062
- Testing
- Integrated Nursing care of placenta previa
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Woman's Health University Hospital, Egypt
Erectile Dysfunction
Evaluate the Safety and Feasibility of Injecting PMD-MSC Into the Penis to Treat the Symptoms of Mild to Moderate ED
Prospective, open-label, non-randomized, study to be conducted at a single center. Ten subjects will undergo an injection of Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs) into the penis for the treatment of mild to…
- Trial name
- PMD-MSC-ED-01 (NCT02398370)
- Testing
- Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Melissa Marchand
Cesarean Section, Affecting Fetus or Newborn
Dexmedetomidine for Cesarean Section
Current cesarean section often chooses spinal anesthesia. And in order to avoid the impact of drugs on the fetus, before the delivery, anesthesiologist generally don't use sedative or analgesic drugs.
- Trial name
- NCT02715154
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University