Clinical trials: Platelet Rich Fibrin
Autotransplantation of Wisdom Teeth, Patelet Rich Fibrin
Auto Transplantation of Wisdom Teeth
Autotransplantation emerges as a viable alternative to tooth extraction and prosthetic restoration when conventional endodontic treatments are unfeasible or contraindicated.
- Trial name
- NCT06553300
- Testing
- Autotransplantation with PRF, Autotransplatation Only
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cleveland Dental Institute
Periodontitis
Efficacy of PRF Application on Clinical Parameters and GCF Platelet-derived Growth Factor-BB and Periostin Levels
Determine the efficacy of the non-invasive application of PRF on periodontal clinical parameters(pocket reduction) and the levels of PDGF-BB and Periostin in the gingival crevicular fluid.
- Trial name
- NCT05178771
- Testing
- Platelet rich fibrin
- Where
- Iraq
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Meniscal Injuries
Novel One-step Repair of Knee Meniscal Tear Using Platelet-rich Fibrin
Currently, most knee meniscal tears are treated by partial or complete meniscectomy, or by suture repair when it is possible. Recently, the investigators have successfully developed and implanted a novel biomaterial…
- Trial name
- NCT01211119
- Testing
- No PRF
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- Taipei Medical University WanFang Hospital
Periodontitis
PLATELET RICH FIBRIN COMBINED WITH 1.2% ATORVASTATIN FOR TREATMENT OF INTRABONY DEFECTS IN CHRONIC PERIODONTITIS
Current study was designed to evaluate the combined efficacy of PRF and 1.2% ATV gel with open flap debridement (OFD) in treatment of intrabony defects in chronic periodontitis subjects.
- Trial name
- NCT02119520
- Testing
- Platelet rich fibrin +Atorvastatin, Platelet rich fibrin, open flap debridement
- Where
- India
- Volunteers
- 96 people
- Sponsor
- Government Dental College and Research Institute, Bangalore
Gingival Recession
Platelet-Rich Fibrin Dressing in the Management of Free Gingival Graft
Evaluation of two dressing materials; a Platelet-Rich Fibrin (PRF) dressing and a non-eugenol-based (Coe-Pak™) dressing in the management of free gingival graft and donor site palatal wound.
- Trial name
- NCT03589235
- Testing
- A free gingival graft, A Platelet-Rich Fibrin dressing, A non-eugenol-based dressing
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University
Immediate Implant Placement
Effect of Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant
The objective of this study will be to compare between Immediate Implant grafted with xenograft and Alb-PRF gel versus xenograft with L-PRF.
- Trial name
- NCT06863051
- Testing
- Immediate Implant Placement and Alb-PRF, Immediate Implant Placement and L-PRF
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Gingival Recession
Evaluating Coronally Advanced Flap With Platelet-rich Fibrin Membrane and Chorion Membrane for Gingival Recession
The present study was a double-blind, randomised, controlled clinical trial with a parallel design, comparing the coronally advanced flap (CAF) with platelet-rich fibrin (PRF) and chorion membrane (CM) for the treatment of…
- Trial name
- NCT07308405
- Testing
- Coronally advanced flap (CAF) with platelet-rich fibrin (PRF), A similar surgical procedure was followed for the recipient bed preparation similar to that for the PRF membrane. A chorion membrane (Tissue bank, Tata Memorial Hospital, Mumbai, Maharashtra, India) o
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institute of Dental Sciences, Bareilly, Uttar Pradesh, India
Periodontal Healing, Periodontitis
The Effectiveness of Root Planing and Injectable Platelet-Rich Fibrin in Smoking Patients With Periodontitis
Periodontitis is a chronic, multifactorial inflammatory disease characterized by the progressive destruction of the tissues supporting the teeth, associated with dysbiotic plaque biofilms.
- Conditions
- Periodontal Healing, Periodontitis, i-PRF
- Trial name
- NCT07049549
- Testing
- Injectable PRF, Plasebo (Sterile Saline)
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Bone Regeneration
Guided Bone Regeneration With L-PRF in the Atrophic Maxilla - The GLAM Technique
16 patients with severe resorbed maxillae referred to Implantology Institute® will be submitted to full arch surgery, with simultaneous implant placement and regeneration in the aesthetic zone, with the GLAM technique.
- Trial name
- NCT03391258
- Testing
- Bone Regeneration with GLAM technique
- Where
- Portugal
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Sinus Lift Augmentation
Albumin-PRF in Sinus Lift With Implants: 2-Year Study
thirty-two implants will be inserted in patients seeking implantation of their lost posterior maxillary teeth (premolar and molars) with limited bone height below the floor of the maxillary sinus, secondary to sinus…
- Trial name
- NCT07367217
- Testing
- lateral sinus lift with using allograft and pericardium membrane, lateral sinus lift with using exteneded platelet rich fibrin
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Alveolar Bone Loss
Comparison of Autogenous Bone Graft and Screw Tent-Pole Technique on Atrophic Mandible
The purpose of the present study was to assess the effect of injectable platelet-rich fibrin (i-PRF) enriched with allograft on alveolar bone regeneration when compared with autogenous block bone graft, in the same participants.
- Trial name
- NCT04133090
- Testing
- Autogenous block bone graft, i-PRF enriched allograft material+ screw tent pole technique
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Ege University
Oral Lichen Planus
Low Level Laser Therapy With Injectable Platelet Rich Fibrin in Management of Oral Lichen Planus
The Injectable PRF (i-PRF) is a variant of PRF, which is a liquid blood derivative rich in leukocytes and acts as a growth factor release, with its potential anti-inflammatory role, it may alleviate the symptoms of OLP.
- Trial name
- NCT07846891
- Testing
- Injectable Platelet Rich Fibrin, Low Level Laser Therapy, Triamcinolone acetonide (injection)
- Where
- 2 sites in Egypt
- Volunteers
- 39 people
- Sponsor
- Ain Shams University
Platelet-rich Fibrin, Bone Substitutes
Horizontal Bone Augmentation of Alveolar Ridge
The objective of this randomized controlled clinical trial was to evaluate the effects of particulate xenogeneic bone grafts associated with autogenous bone graft or Leukocyte-and-Platelet-Rich Fibrin (L-PRF) for horizontal…
- Conditions
- Platelet-rich Fibrin, Bone Substitutes, Atrophic Maxilla, Cone-beam Computed Tomography
- Trial name
- NCT06420713
- Testing
- Horizontal Bone Augmentation of Alveolar Ridge, Groups, Dental Implants
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- University of Sao Paulo
Alveolar Bone Loss
Alveolar Ridge Augmentation Using Minimally Invasive Subperiosteal Tunneling With Xenogenic Bone Graft and PRF
surgical horizontal augmentation for maxillary alveolar ridge using minimally invasive subperiosteal tunneling in comparison to conventional surgical technique
- Trial name
- MISTT (NCT07079917)
- Testing
- subperiosteal tunneling for horizontal alveolar ridge augmentation, conventional alveolar ridge augmentation
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Fayoum University
Venous Leg Ulcers
A Prospective, Randomized Clinical Trial of PRP Concepts Fibrin Bio-Matrix in Chronic Non-Healing Venous Leg Ulcers
To assess the efficacy of the PRP Concepts Fibrin Bio-Matrix and compare its performance with usual and customary practice for the treatment of chronic non-healing venous leg ulcers (VLU).
- Trial name
- NCT02312518
- Testing
- PRP Concepts Fibrin Bio-Matrix, Usual and Customary Practice
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- PRP Concepts, LLC
Necrotic Pulp
Comparative Evaluation of the Regenerative Capacity of Two Platelet Concentrates
Injectable platelet-rich fibrin (I-PRF) is a flowable blood concentrate that is entirely natural and allows ease of access and flow within the root canal. It was first developed in 2014 by modifying the centrifugation parameters.
- Trial name
- NCT03698188
- Testing
- Injectable platelet-rich fibrin, Platelet-rich plasma
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Patients With Missing Teeth
Platelet Rich Fibrin Versus Melatonin Around Dental Implants
Dental implant is a dental treatment that allow oral rehabilitation for partial and fully edentulous patients. Osteointegration is the factor that control success s or failure of dental implant that can be improved by addition of…
- Trial name
- NCT05593731
- Testing
- dental implants with melatonin gel
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Gingival Recession
Clinical Evaluation of Injectable Platelet Rich Fibrin With Connective Tissue Graft for the Treatment of Deep Gingival Recession Defects.
Aim: The aim of this study was to determine whether the combined connective tissue graft (CTG) with injectable platelet rich fibrin (i-prf) with coronally advanced flap (CAF) improved root coverage of deep Miller Class I or II…
- Trial name
- NCT04032405
- Testing
- CAF+CTG+i-prf
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Gingival Recession
Evaluation of Esthetic Root Coverage Using Platelet-Rich Fibrin Versus Subepithelial Connective Tissue Graft With Vestibular Incision Subperiosteal Tunnel Access in Multiple Gingival Recessions
Patients with gingival recession, complain of excessive tooth length that affects their appearance during smiling or functioning.
- Trial name
- NCT03588052
- Testing
- VISTA using PRF, VISTA using SCTG
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Implant Failed, Platelet-rich Fibrin
Evaluation of Dental Implants Placed in Preserved and Non-preserved Post-extraction Ridges
A prospective study to evaluate and compare implants placed in preserved versus non-preserved extraction sockets using L-PRF (Leucocyte- and platelet-rich fibrin) after 1, 3 and 5 years.
- Conditions
- Dental Implant Failed, Platelet-rich Fibrin, Alveolar Rege Preservation, Alveolar Bone Loss
- Trial name
- NCT03715439
- Testing
- Dental implant
- Where
- 2 sites in Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University