Clinical trials: Polyp of Large Intestine
Colorectal Polyp, Obesity
Feasibility and Colorectal Benefits of Pulses Supplementation
Beans are a forgotten staple food that shows promise in improving health. The goal of this study is to look at how bean supplementation affects metabolic and bowel health.
- Trial name
- NCT06032104
- Testing
- Dry beans, Usual diet
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Benign Polyps of Large Intestine
Resect and Discard Approach to Diminutive Colonic Polyps
Resect and discard (RD) is a new paradigm for management of diminutive colorectal polyps wherein histology is determined by real-time endoscopic imaging; polyps are then resected and discarded rather than sent for…
- Trial name
- RD (NCT01877525)
- Testing
- Colonoscopy
- Where
- United States
- Volunteers
- 618 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Colorectal Polyps
Discard:Characterisation of Colonic Polyps in Vivo
Prospective study of accuracy of colonic polyp characterisation in vivo using high resolution white light endoscopy, narrow band imaging and chromoendoscopy.
- Trial name
- DISCARD (NCT00888771)
- Where
- United Kingdom
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Colorectal Polyp
Comparative Study of Anchoring-tip vs. Conventional EMR of Colorectal Polyps
Endoscopic mucosal resection (EMR) is an effective and has been widely used technique for the treatment of superficial colorectal neoplasms.
- Trial name
- NCT04825457
- Testing
- Anchoring-tip vs. Conventional
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Chilgok Hospital
Colorectal Cancer, Polyps
Aspirin/Folate Prevention of Large Bowel Polyps
This is a randomized controlled trial of aspirin and/or folate supplementation for the prevention of the recurrence of neoplastic polyps (adenomas) of the large bowel.
- Conditions
- Colorectal Cancer, Polyps, Adenomas
- Trial name
- NCT00272324
- Testing
- Aspirin, Folate
- Where
- 9 sites in United States, Canada
- Volunteers
- 1,121 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Colonic Polyp
Implementation of Optical Diagnosis of Diminutive Colorectal Polyps: DISCARD3 Study (Incorporating AI-DETECT)
This is a prospective feasibility study. The aim of this work is to assess the acceptability and feasibility of optical diagnosis-led care in bowel cancer screening patients undergoing colonoscopy.
- Trial name
- NCT04710693
- Testing
- CAD polyp-detection system
- Where
- United Kingdom
- Volunteers
- 614 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Colorectal Polyp, Linked Color Imaging
Computer-assisted Diagnosis System Based on Linked Colour Imaging
Linked color imaging (LCI)，a new endoscopy modality, creates clear and bright images by using short wavelength narrow band laser light. LCI can make red area appear redder and white areas appear whiter.
- Conditions
- Colorectal Polyp, Linked Color Imaging, Computer-aided Diagnosis
- Trial name
- NCT03359343
- Where
- 2 sites in China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Adenoma Colon, Serrated Polyp
Cold EMR Vs Standard EMR for the Treatment of Large Nonpedunculated Homogeneous Colorectal Lesions
This study compares the effectiveness in complete resection (absence of recurrence at 6 months) the two different techniques for performing endoscopic mucosal resection (EMR) of nonpedunculated homogeneous colorectal lesions >20mm
- Conditions
- Adenoma Colon, Serrated Polyp, Serrated Adenoma, Colorectal Neoplasms
- Trial name
- NCT04418843
- Testing
- Standard Endoscopic Mucosal Resection, Cold Snare Endoscopic Mucosal Resection
- Where
- Spain
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Oscar Nogales
Barrett Esophagus, Polyps
A Prospective Study Comparing the Accuracy of Olympus Lucera Spectrum Technology vs Olympus Lucera Elite Technology in the in Vivo Diagnosis of Barrett's Oesophagus and Colorectal Polyps: The ELITE Study
Barrett's oesophagus is a condition where the lining of the oesophagus (gullet) wall changes. People with Barrett's oesophagus are at risk of developing oesophageal cancer but can have regular checkups to detect changes before…
- Trial name
- ELITE (NCT03073226)
- Testing
- Olympus Elite, Olympus Spectrum
- Where
- United Kingdom
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Colorectal Polyp, Colorectal Adenoma
Standard Colonoscopy Versus Colonoscopy With Endocuff Vision
This study seeks to compare colonoscopy results between a standard method and one using a distal scope attachment (Endocuff Vision).
- Conditions
- Colorectal Polyp, Colorectal Adenoma, Colon Cancer
- Trial name
- NCT03361917
- Testing
- Endocuff Vision
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colon Polyps
Real-time Diagnosis of Colorectal Polyps Using Narrow-Band Imaging
Accurate optical diagnosis of colorectal polyps could allow a "resect and discard" strategy with surveillance intervals determined based on the results of the optical biopsy.
- Trial name
- NCT02516748
- Testing
- Feedback
- Where
- South Korea
- Volunteers
- 3,268 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Colorectal Polyps
Comparison of Two Types of Biopsy Forceps for Obtaining Cold Biopsy Polypectomy for Small Sessile Colorectal Polyps Less Than 6 mm in Diameter
The purpose of this study is to evaluate the efficacy of the new RJ4 compare with the standard RJ3 biopsy forceps for performing polypectomy for small colorectal polyps.
- Trial name
- NCT00855790
- Testing
- evaluate the effectiveness of the RJ4 biopsy forcep versus the RJ3 biopsy forcep
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Florida
Colorectal Neoplasms, Colorectal Cancer
Microbiome Test for the Detection of Colorectal Polyps and Cancer
The purpose if this study is to measure the sensitivity, specificity and accuracy of the Metabiomics Colon Polyp and Colorectal Cancer Assay for the non-invasive detection of colon polyps or colorectal cancer.
- Trial name
- NCT02141945
- Where
- 2 sites in United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Metabiomics Corp
Colorectal Neoplasms
Study of Folic Acid, Calcium and Vitamin D in Preventing Colorectal Polyps and Colorectal Cancer
Folic acid (FA) and its derivatives (folate) which play a role in nucleotide synthesis and methylation reactions as well as calcium and vitamin D are assumed to be effective in the prevention of colorectal polyps and Colorectal…
- Trial name
- NCT02066688
- Testing
- folic acid, folic acid calcium vitamin D3, calcium
- Where
- China
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Polyp Colorectal, Endoscopic Mucosal Resection
Structured TXI-RDI Integration for Endoscopic Resection
The goal of this clinical research study is to learn whether two advanced imaging tools, called Texture and Color Enhancement Imaging (TXI) and Red Dichromatic Imaging (RDI), can make the removal of large colon polyps safer…
- Trial name
- STRIkER (NCT07474844)
- Testing
- Texture and Color Enhancement Imaging (TXI) and Red Dichromatic Imaging (RDI), High Definition White Light Endosocopy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Colonic Polyps, CRC (Colorectal Cancer)
A Prospective Study to Evaluate the Performance of a Real-time System in the Estimation of Colorectal Polyp Size
Colorectal polyp size is related to the risk of exhibiting advanced histological features. Moreover, polyps larger than 10 mm are associated with an elevated risk of metachronous advanced neoplasia and colorectal cancer (CRC).
- Conditions
- Colonic Polyps, CRC (Colorectal Cancer), Artificial Intelligence (AI)
- Trial name
- EndoAIM (NCT06957015)
- Testing
- EndoAIM
- Where
- Hong Kong
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal Polyp
The Impact of Repeated Colonoscopic Insert Method on the Detection Rate of Adenomas in the Sigmoid Colon
Colorectal cancer (CRC) is a malignant tumour originating from the colorectal mucosal epithelium, with rising incidence and mortality rates.
- Trial name
- NCT06186778
- Testing
- secondary colonoscopy, conventional colonoscopy
- Where
- China
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Jianning Yao
Adenomatous Polyp of Large Intestine
Prophylactic Coagulation for the Prevention of Bleeding in Endoscopic Mucosal Resection of Large Sessile Colonic Polyps
The hypothesis of this study is that prophylactic coagulation therapy with coagulation forceps to visible vessels within the mucosal defect for colonic Endoscopic Mucosal Resection (EMR) will reduce the rate of delayed bleeding…
- Trial name
- NCT01368731
- Testing
- Prophylactic use of coagulation therapy
- Where
- Australia
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Professor Michael Bourke
Colorectal Neoplasms, Colorectal Cancer
Bile Acids and Microbiome in Early Colorectal Carcinogenesis
Currently colorectal cancer pathogenesis is mainly explained by the adenoma-carcinoma sequence theory that was proposed more than half a century ago.
- Conditions
- Colorectal Neoplasms, Colorectal Cancer, Colorectal Polyp, Microbiome
- Trial name
- NCT06502704
- Where
- Lithuania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Polyp Colorectal, Adenoma Colon
AI Colorectal Polyp Detection
This study is intended to demonstrate the superiority of colorectal polyp detection using computer-assisted colonoscopy compared to conventional colonoscopy.
- Trial name
- NCT04979962
- Testing
- EW10-EC02 (Endoscopy Support Program)
- Where
- 10 sites in United States
- Volunteers
- 1,162 people, healthy volunteers welcome
- Sponsor
- Fujifilm Medical Systems USA, Inc.