Clinical trials: Popliteal Artery Occlusion
Peripheral Arterial Disease, Critical Lower Limb Ischemia
Safety and Feasibility of Surmodics SUNDANCE™ Drug Coated Balloon
To evaluate the safety and performance of the Sundance™ DCB in subjects with occlusive disease of the infrapopliteal arteries.
- Trial name
- SWING (NCT04107298)
- Testing
- SUNDANCE™ Drug Coated Balloon
- Where
- 8 sites in Australia, Austria and 3 more
- Volunteers
- 35 people
- Sponsor
- SurModics, Inc.
Peripheral Artery Disease
ILLUMENATE Pivotal Post-Approval Study (PAS)
The ILLUMENATE Pivotal PAS is a continued follow-up study which will include 300 subjects from forty-three (43) sites across the United States and Austria previously enrolled in the ILLUMENATE Pivotal pre-market study to evaluate…
- Trial name
- NCT03421561
- Testing
- Stellarex 0.035" OTW Drug-coated Angioplasty Balloon, EverCross™ 0.035 PTA Balloon Catheter
- Where
- 41 sites in United States, Austria
- Volunteers
- 300 people
- Sponsor
- Spectranetics Corporation
Femoral Artery Stenosis, Femoral Artery Occlusion
A Single Arm Trial Evaluating the BARD Lutonix Drug-Coated Balloon (LTX DCB) for Treatment of Femoropopliteal Arteries
To assess the safety and efficacy of the BARD LTX DCB for treatment of stenosis or occlusion of the superficial femoral and popliteal arteries.
- Conditions
- Femoral Artery Stenosis, Femoral Artery Occlusion, Stenosis of Popliteal Arteries, Occlusion of Popliteal Arteries
- Trial name
- NCT02720003
- Testing
- LTX DCB
- Where
- 14 sites in China
- Volunteers
- 148 people
- Sponsor
- C. R. Bard
Knee Arthroplasty, Total
BLOCK-study: Better Local Orthopedic Pain Control After Knee Arthroplasty
The goal of this study is to compare the anesthetic combination iPACK with femoral triangle block versus surgical LIA for unilateral TKA.
- Trial name
- BLOCK (NCT06746168)
- Testing
- Locoregional anesthesia, Local Anesthetic Ropivacaine
- Where
- Belgium
- Volunteers
- 210 people
- Sponsor
- Jessa Hospital
Peripheral Arterial Disease
The Inperia Advance Post-Market Retrospective Study
The Inperia Advance Carbostent™ is a CE-marked infra-popliteal stent for treatment of infra-popliteal artery stenosis. The aim of this post-market retrospective study protocl P32203 is to collect clinical data of patients treated…
- Trial name
- NCT05622084
- Testing
- Inperia Advance
- Where
- France
- Volunteers
- 32 people
- Sponsor
- CID S.p.A.
Lower Limb Ischemia, Peripheral Arterial Disease
The PORTuguese Registry of Supera Supported Femoral-Fopliteal Revascularization (SupPORT Registry)
The SupPORT Registry aims at collecting real-world from Portuguese centers performing femoral-popliteal revascularization with Supera (r) implants. This is a prospective non-randomized non-controlled consecutive registry.
- Conditions
- Lower Limb Ischemia, Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia, Chronic Limb Ischemia
- Trial name
- SupPORT regist (NCT06416644)
- Testing
- Supera Vasculomimetic Stent
- Where
- 15 sites in Portugal
- Volunteers
- 100 people
- Sponsor
- Hospital do Divino Espírito Santo de Ponta Delgada
Post Operative Pain
Analgesic Efficacy of Genicular Nerve Block Versus (IPack Block ) in Patients Undergoing (ACL) Repair
One of the most common injuries to the knee is an anterior cruciate ligament (ACL) sprain or tear due to trauma ACL damage is crippling and often requires repair with an arthroscopic method, which is an outpatient surgery.
- Trial name
- NCT06404658
- Testing
- Genicular nerve block
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Knee Osteoarthritis, Knee Pain Chronic
Dexamethasone for iPACK Block With ACB in Total Knee Arthroplasty
Effect of adding Dexamethasone to Infiltration between the Popliteal Artery and Capsule of the Knee Block with ACB in Patients undergoing Total Knee Arthroplasty
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis
- Trial name
- NCT06470204
- Testing
- Ropivacaine, Ropivacaine+Dexamethasone
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Peripheral Arterial Disease
A Superiority Trial of the SUPERA Peripheral Stent System in Patients With Femoro-popliteal Artery Disease
The purpose of this study (superiority trial) is to compare the Supera® Peripheral Stent System with a standard nitinol self-expanding stent for treatment of femoro-popliteal arterial occlusive disease.
- Trial name
- NCT03941314
- Testing
- Supera® Peripheral Stent System, EverFlex™ Self-Expanding Peripheral Stent System
- Where
- 3 sites in Spain, Switzerland
- Volunteers
- 300 people
- Sponsor
- Kantonsspital Winterthur KSW
Patients Undergoing Arthroscopic Knee Surgery
Evaluation of the Effectiveness of iPACK and Adductor Canal Blocks on Patients Undergoing Arthroscopic Knee Surgery
Arthroscopic knee surgery is one of the most commonly performed procedures in orthopedic surgery. More than 50% of patients experience moderate to severe pain after the operation.
- Trial name
- NCT07002580
- Testing
- IPACK and adductor canal block with Bupivacaine 0.25%, Spinal Anesthesia with Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Sakarya University
Peripheral Arterial Disease
Endovascular Procedures With Computer Assistance in the Chronic Occlusive Arthritis of the Lower Limbs on the Femoro-popliteal Stage.
Pilot study to assess the feasibility of creation of a bone and arterial panorama by 2D-2D registration technique during endovascular femoro-popliteal procedures with a mobile C-arm X-ray system using EndoNaut® software.
- Trial name
- PANORAMIC (NCT03669978)
- Testing
- Creation of a bone and arterial panorama using EndoNaut® software.
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Rennes University Hospital
Peripheral Arterial Disease
Efficacity Study With the Protégé EverFlex Stent in Popliteal Lesions
This study will assess the results up to 12 months with the Protégé EverFlex stent (ev3) in patients presenting with a narrowing or blocking at the level of the knee artery, which leads to a limited walking distance, rest pain or…
- Trial name
- DUR-POP (NCT01412450)
- Testing
- nitinol stent
- Where
- 4 sites in Belgium
- Volunteers
- 60 people
- Sponsor
- Flanders Medical Research Program
Iliac Artery Stenosis, Iliac Artery Occlusion
Safety and Efficacy Study of GoldenFlow Peripheral Stent System
A Prospective, Multi-center, Single-Arm Clinical Trial to evaluate the safety and efficacy of the GodenFlow Peripheral Stent System manufactured by Lifetech Scientific (Shenzhen) Co., LTD.
- Conditions
- Iliac Artery Stenosis, Iliac Artery Occlusion, Femoral Artery Stenosis, Femoral Artery Occlusion
- Trial name
- NCT03687983
- Testing
- GoldenFlow Peripheral Stent System
- Where
- 12 sites in China
- Volunteers
- 90 people
- Sponsor
- Lifetech Scientific (Shenzhen) Co., Ltd.
Peripheral Arterial Disease
SAFE (Sarpogrelate Anplone in Femoro-popliteal Artery Intervention Efficacy) Study
After endovascular treatment (EVT) for peripheral artery disease (PAD), dual antiplatelet therapy (DAAT) of aspirin (ASA) and clopidogrel are currently drug of choice to prevent occlusion.
- Trial name
- NCT02959606
- Testing
- Sarpogrelate SR 300mg, Clopidogrel
- Where
- South Korea
- Volunteers
- 272 people
- Sponsor
- Seoul National University Hospital
Peripheral Arterial Disease, Peripheral Vascular Disease
Evaluation of the Safety and Efficacy of a Vascular Prosthesis as an Above-Knee Bypass Graft in Patients With PAD
The purpose of this study is to assess the safety and efficacy of a novel, tissue-engineered vascular prosthesis, the Human Acellular Vessel (HAV).
- Trial name
- NCT01872208
- Testing
- HAV implantation
- Where
- 3 sites in Poland
- Volunteers
- 20 people
- Sponsor
- Humacyte, Inc.
Femoral Artery Stenosis, Popliteal Artery Stenosis
Lutonix Drug Coated Balloon for Treatment of Femoropopliteal Arteries in United States Females (CONFIRM)
The post approval study will enroll US female patients presenting with claudication or ischemic rest pain and an angiographically significant lesion in the superficial femoral or popliteal artery.
- Conditions
- Femoral Artery Stenosis, Popliteal Artery Stenosis, Femoral Artery Occlusion, Popliteal Artery Occlusion
- Trial name
- CONFIRM (NCT02813577)
- Testing
- Lutonix® 035 Drug Coated Balloon PTA Catheter
- Where
- 4 sites in United States
- Volunteers
- 4 people
- Sponsor
- C. R. Bard
Knee Injuries
Comparison of IPACK and Adductor Canal Block Combination Versus Epidural Analgesia for Total Knee Arthroplasty
To compare the efficacy and complications of IPACK and adductor canal block combination and epidural block in patients who will be operated for knee arthroscopy under spinal anesthesia.
- Trial name
- NCT05751109
- Testing
- ipack+adduktor kanal
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Pain After Total Knee Arthroplasty, Pain, Postoperative
Comparison of BiFeS + ACB and IPACK + ACB Block Combinations for Postoperative Pain After Total Knee Arthroplasty
This prospective observational study will compare the postoperative analgesic efficacy of two multimodal regional anesthesia combinations routinely used after total knee arthroplasty (TKA) performed under spinal anesthesia.
- Conditions
- Pain After Total Knee Arthroplasty, Pain, Postoperative, Arthroplasty, Replacement, Knee
- Trial name
- NCT07231692
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Knee Arthroplasty, Total
Comparison of the Analgesic Efficacy of Adductor Canal Block and Combined Adductor Canal Block Plus IPACK Block in Knee Surgery
To evaluate the effectiveness of Adductor Canal Block and combined Adductor Canal plus IPACK block in reducing postoperative pain and analgesic requirements in patients undergoing knee surgery.
- Trial name
- NCT07526831
- Testing
- Adductor Canal Block Group (Group I), Adductor Canal + iPACK Block Group (Group II)"
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Total Knee Arthroplasty, Ultrasound Guided Supra-inguinal Fascia Iliaca Block
Comparison of Two Different Regional Anesthetic Methods in Total Knee Arthroplasty Patients
Total Knee Arthroplasty patients are among the orthopedic cases that experience severe postoperative pain. In these cases, pain must be controlled. If pain is not controlled, early mobilization cannot be achieved.
- Conditions
- Total Knee Arthroplasty, Ultrasound Guided Supra-inguinal Fascia Iliaca Block, Adductor Canal Block
- Trial name
- NCT07092982
- Testing
- Ultrasound Guided Suprainguinal Fascia Iliaca Block, Ultrasound Guided Adductor Canal Block, Ultrasound Guided iPACK Block
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- SB Istanbul Education and Research Hospital