Clinical trials: Positron-Emission Tomography(PET)
PCA, Prostate Cancer
PSMA PET Combined With MRI for the Detection of PCa
This is an open label, longitudinal Phase 3 study of prostate specific membrane antigen (PSMA) positron emission tomography (PET) combined with magnetic resonance imaging (MRI) compared to standard of care (SOC) for the detection…
- Conditions
- PCA, Prostate Cancer, Prostatic Neoplasm, PSMA PET
- Trial name
- BiPASS (NCT07052214)
- Testing
- 68Ga-PSMA-11
- Where
- 18 sites in United States, Australia
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- Telix Pharmaceuticals (Innovations) Pty Limited
Glioma Glioblastoma Multiforme, Glioma, High Grade
PET-Guided Resection in High-Grade Gliomas
Background: Glioblastoma (GBM) is the most common primary brain tumor in adults, with a poor prognosis despite maximal treatment.
- Conditions
- Glioma Glioblastoma Multiforme, Glioma, High Grade, Glioma Surgery, Positron-Emission Tomography(PET)
- Trial name
- ResPGlioma (NCT07567196)
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Universita degli Studi di Genova
Huntington Disease, HD
iMagemHTT-009- FIH Evaluation of Novel Mutant Huntingtin PET Radioligand [11C]CHDI-00491009
This is a FIH (first-in-human) study to evaluate the clinical utility of the radioligand [11C]CHDI-00491009 as a PET tracer that binds specifically to mutant huntingtin (mHTT) aggregates in Huntington's disease (HD).
- Conditions
- Huntington Disease, HD, PET Tracer, Positron Emission Tomography
- Trial name
- iMagemHTT-009 (NCT06634628)
- Testing
- Radioligand [11C]CHDI-00491009
- Where
- Belgium
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- CHDI Foundation, Inc.
Solid Tumor, Positron-Emission Tomography(PET)
Phase I Clinical Trial of 68Ga-NOTA-SNA002
The clinical trial was a single-center, dose-increasing, open trial.In this clinical trial, 68Ga-NOTA-SNA002 was injected intravenously to observe its safety tolerance, radiation absorption dose, distribution characteristics…
- Trial name
- NCT05989997
- Testing
- 68Ga-NOTA-SNA002
- Where
- China
- Volunteers
- 17 people
- Sponsor
- SmartNuclide Biopharma
Kidney Neoplasms / Surgery, Glomerular Filtration Rate
The Study on the Effectiveness of [68Ga]Ga-HBED-CC-DiAsp PET/CT in Calculating GFR and Predicting Residual Renal Function After Partial Nephrectomy
In subjects with different levels of renal function and no history of renal tumors, GFR is measured using [68Ga]Ga-HBED-CC-DiAsp PET/CT, the Gates method, and the 99mTc-DTPA dual plasma method.
- Conditions
- Kidney Neoplasms / Surgery, Glomerular Filtration Rate, Positron-Emission Tomography(PET)
- Trial name
- NCT06973798
- Testing
- GFR will be measured using three methods at two weeks before surgery and four ± one week after surgery, GFR will be measured using three methods: [68Ga]Ga-HBED-CC-DiAsp PET/CT, the Gates method, and the dual plasma sampling method with 99mTc-DTPA.
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Luo Yaping
Prostate Cancer (Diagnosis), Prostate-specific Membrane Antigen
Intratumoral Heterogeneity on [18F]PSMA and [18F]FDG PET/CT in Predicting Invasion and Prognosis of Prostate Cancer
The purpose of this study is to analyze heterogeneity of prostate cancer（PCa）based on the head-to-head imaging of prostate-specific membrane antigen (PSMA) and fluorodeoxyglucose (FDG) positron emission tomography computed…
- Conditions
- Prostate Cancer (Diagnosis), Prostate-specific Membrane Antigen, Positron Emission Tomography (PET)
- Trial name
- NCT06919159
- Testing
- PSMA PET/CT scan, FDG-PET
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Jiequn Yu
Positron-Emission Tomography(PET), Prostate Cancer
A Multicenter Study Evaluating the Diagnostic Value of 68Ga-MY6349 PET/CT for Prostate Cancer
The main objective of this research is to develop and evaluate new PET imaging agents with high sensitivity and specificity for prostate cancer and other aggressive tumors.
- Conditions
- Positron-Emission Tomography(PET), Prostate Cancer, Trophoblast Cell Surface Antigen 2
- Trial name
- NCT06696326
- Testing
- standard-of-care imaging 68Ga-MY6349 and 68Ga-PSMA-11
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Sepsis, AKI - Acute Kidney Injury
Mechanisms of Acute Kidney Injury in Severe Infections
Renal perfusion and neutrophil-mediated inflammation will be assessed in the kidney in sepsis patients with acute kidney injury using positron emission tomography.
- Conditions
- Sepsis, AKI - Acute Kidney Injury, Positron Emission Tomography (PET)
- Trial name
- PET-AKI (NCT06372444)
- Testing
- Positron emission tomography (PET)
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Uppsala University Hospital
MRI, PET Scan
Validation of PET-MRI for Cardiovascular Disease
To determine whether PET-MRI can obtain comparable images to PET-CT in those with coronary artery disease.
- Conditions
- MRI, PET Scan, Positron-Emission Tomography, Cardiovascular Disease
- Trial name
- NCT02988531
- Testing
- PET/MR scan
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Edinburgh
Solid Tumor, Positron-Emission Tomography(PET)
[68Ga]Ga-NOTA-SNA002 (PD-L1 PET Tracer) for PET/CT in Patients With Solid Tumors
The purpose of this study is to evaluate the safety of [68Ga]Ga-NOTA-SNA002 and investigate the uptake of [68Ga]Ga-NOTA-SNA002 in patients with solid tumors.
- Trial name
- NCT05490264
- Testing
- [68Ga]Ga-NOTA-SNA002
- Where
- China
- Volunteers
- 20 people
- Sponsor
- SmartNuclide Biopharma
Positron Emission Tomography-Magnetic Resonance (PET-MR)
Enhancing SUV Accuracy of PET/MR for Clinical Trial Qualification
Standardized Uptake Values (SUVs), normalized activity concentration, measured using PET/MR have inaccuracies ≥ 20% which exceeds National Cancer Institute / American College of Radiology Imaging Network (NCI/ACRIN), Radiological…
- Trial name
- NCT03603925
- Testing
- Positron Emission Test / Magnetic Resonance (PET/MR), Positron Emission Test / Computed Tomography (PET/CT)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Case Comprehensive Cancer Center
Rosuvastatin, Heart Failure
Dutch Sub Study: Controlled Rosuvastatin Multinational Study in Heart Failure (CORONA). PET Sub Study
At one site, patients participating in the Corona main study are asked to participate in the PET-substudy. Before and 6 months after study medication is started a Positron Emission Tomography (PET-scan) is performed to study the…
- Conditions
- Rosuvastatin, Heart Failure, Positron Emission Tomography (PET)
- Trial name
- NCT00228514
- Testing
- Rosuvastatin, Positron emission tomography
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- AstraZeneca