Clinical trials: Post Menopause
Postmenopausal, Female
How Seasons Affect Kidney Health in Post-Menopausal Females
The investigators are assessing how seasonal changes affect kidney function biomarkers in post-menopausal women, an understudied group.
- Trial name
- NCT06866743
- Testing
- There will be no intervention.
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Florida State University
Dry Eye Syndromes
Effects of RP101 in Post-menopausal Women With Dry Eye Syndrome
The main purpose of this study is to establish whether RP101 can reduce symptoms of dry eye syndrome in post-menopausal women.
- Trial name
- NCT03821415
- Testing
- RP101
- Where
- 8 sites in Austria, Germany and 1 more
- Volunteers
- 104 people
- Sponsor
- Redwood Pharma AB
Post Menopausal Osteoporosis
Phase 2 Study of BA058 (Abaloparatide) Transdermal Delivery in Postmenopausal Women With Osteoporosis
To determine the clinical safety and efficacy of abaloparatide transdermal in otherwise healthy postmenopausal women with osteoporosis as assessed by changes in bone mineral density (BMD) and serum markers of bone metabolism when…
- Trial name
- NCT01674621
- Testing
- Abaloparatide Transdermal (50 mcg), Abaloparatide Transdermal (100 mcg), Abaloparatide Transdermal (150 mcg)
- Where
- 9 sites in United States, Denmark and 2 more
- Volunteers
- 250 people
- Sponsor
- Radius Health, Inc.
Endometrial Cancer
Study of BN83495 in Post-menopausal Women With Endometrial Cancer Post-chemotherapy
The purpose of the protocol is to determine the effect of BN83495 on the progression of endometrial cancer with estrogen receptor in post menopausal women who had previously received chemotherapy.
- Trial name
- NCT01251354
- Testing
- BN83495
- Where
- 9 sites in United States, Canada
- Volunteers
- 6 people
- Sponsor
- Ipsen
Breast Cancer
Palbociclib In Combination With Letrozole As Treatment Of Post-Menopausal Women With HR+, HER2- Advanced Breast Cancer
A study of palbociclib in combination with letrozole as treatment of post-menopausal women with hormone receptor-positive, her2-negative advanced breast cancer for whom letrozole therapy is deemed appropriate.
- Trial name
- NCT02679755
- Testing
- Palbociclib, Letrozole
- Where
- 34 sites in Australia, India
- Volunteers
- 252 people
- Sponsor
- Pfizer
Advanced Breast Cancer
Pilot Decentralized Clinical Trial in Men and Pre and Post-menopausal Women With Breast Cancer and a Specific Mutation (PIK3CA) Treated With Alpelisib in Combination With Fulvestrant
The study was designed to identify and register practical observations and experiences in connection with planning and implementing decentralized, patient-centered clinical trials at a geographic distance with virtual elements.
- Trial name
- TELEPIK (NCT04862143)
- Testing
- Alpelisib, Fulvestrant, Goserelin
- Where
- Sweden
- Volunteers
- 2 people
- Sponsor
- Novartis Pharmaceuticals
Major Depressive Disorder, Vasomotor Symptoms
Desvenlafaxine Succinate (Pristiq): Postmarketing Surveillance Study Among Filipino Patients
This is a non-interventional study to review safety data on administration of desvenlafaxine succinate among Filipino patients with MDD and VMS per usual clinical practice within the first three years post commercial distribution.
- Trial name
- NCT01353963
- Testing
- desvenlafaxine succinate
- Where
- 3 sites in Philippines
- Volunteers
- 13 people
- Sponsor
- Pfizer
Overactive Bladder, Urge Urinary Incontinence
Bryophyllum Pinnatum Versus Solifenacin Versus Placebo for Overactive Bladder
Overactive bladder (OAB) is an enigmatic condition that is treated symptomatically with anticholinergic drugs (gold standard 2013).
- Trial name
- BryoSoliP (NCT02129816)
- Testing
- Bryophyllum
- Where
- 2 sites in Switzerland
- Volunteers
- 9 people
- Sponsor
- University of Zurich
Aging, Postmenopause
Oral Antioxidant Therapy Targeted to the Mitochondria for Improving Brain Artery Health in Postmenopausal Women
The goal of this clinical trial is to learn if 3 months of taking the dietary supplement MitoQ [a mitochondria-targeted antioxidant that targets to reduce mitochondrial reactive oxygen species (mitoROS)] works to treat age- and…
- Trial name
- NCT07406243
- Testing
- Mitoquinone (MitoQ)
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Colorado State University
Menopause
Impact of Egg Consumption on Carotenoid and Vitamin D Bioavailability in Pre- and Post-menopausal Women
The 2010 Dietary Guidelines for Americans emphasizes consumption of 4.5 cups of fruits and vegetables daily but the average intake of US adults is only 2.6 cups.
- Trial name
- NCT02679794
- Testing
- Egg consumption, Control
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Osteoporosis in Post-menopausal Women, Prevention
Development of a Wearable Device for Osteoporosis Prevention and Fracture Risk Reduction in Women
This project aims to determine the impact on bone health of: A lifestyle intervention promoting impact-based activities and physical activity for nine months. The same program enhanced with home-based strength training.
- Conditions
- Osteoporosis in Post-menopausal Women, Prevention, Exercise, Physical Activity
- Trial name
- Weapom (NCT06741956)
- Testing
- Weapom Lifestyle Intervention to measure bone impacts using a Fitbit Versa wearable device and the Weapom App.
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Seville
Bone Fracture
Metformin Effect on Fracture Healing in Post-Menopausal Women
study the effect of metformin drug on fracture healing of patients with high risk of delayed fracture healing or non-union and correlating this to serum irisin myokine level.
- Trial name
- NCT03845153
- Testing
- Metformin Retard 850 mg
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Damanhour University
Obesity, Menopause
Aging Well: Targeting Obesity With GLP-1 Agonists to Enhance Physical and Vascular Health in Postmenopausal Women
In postmenopausal women, obesity increases the risk of physical function decline, premature aging, and vascular dysfunction. Semaglutide and tirzepatide are potent obesity medications.
- Trial name
- NCT07057310
- Testing
- semaglutide or tirzepatide, Lifestyle modification intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Bone Diseases, Cardiovascular Diseases
CVD Risk and Health in Postmenopausal Phytoestrogen Users
To determine the acceptability and benefits of use of a dietary supplement of the phytoestrogen, genistein, versus placebo on heart disease risk factors, bone density, and psychosocial outcomes in postmenopausal women.
- Conditions
- Bone Diseases, Cardiovascular Diseases, Coronary Disease, Depression
- Trial name
- NCT00000613
- Testing
- dietary supplements, genistein, diet, soy proteins
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Ovarian Failure, Infertility
Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy
Background: Medical advances have improved survival rates for many cancers and other illnesses. This means that more people are coping with the long-term effects of these treatments. Some treatments can cause female infertility.
- Conditions
- Acute Ovarian Failure, Infertility, Early Menopause And Infertility In Females After Treatment For Childhood Cancer
- Trial name
- NCT05440617
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Breast Cancer, Genitourinary Syndrome of Menopause
Sexual and Vaginal Health in Breast Cancer Women Receiving Aromatase Inhibitors Before and After CO2 Laser Therapy
Background: Vulvovaginal health, directly linked to sexual health, is a key factor for female pleasure. BCS receiving AI are likely to present severe GSM and sexual complaints.
- Trial name
- LIGHT (NCT04619485)
- Testing
- CO2 LASER
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Hospital Clinic of Barcelona
Postmenopause, Premenopause
Marine n-3 Polyunsaturated Fatty Acids in Pre- and Postmenopausal Women
The study is a randomised placebo controlled double-blinded clinical trial where a group of healthy pre- and postmenopausal women is randomised to the intake of fish oil capsules or placebo oil capsules for 12 weeks.
- Trial name
- NCT00901589
- Testing
- marine n-3 polyunsaturated fatty acids, thistle oil
- Where
- Denmark
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Osteoporosis, Postmenopausal, Physical Activity
Efficacy and Safety of the Physical Activity Program in Women With Post-menopausal Osteoporosis
The study will be single blinded since professionals who will evaluate patients will not know to which exercise group patients have been assigned.
- Trial name
- ACTLIFE (NCT04179903)
- Testing
- Physical activity
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Istituto Ortopedico Rizzoli
Postmenopausal
Effect of 17ß-estradiol on Inflammatory-immune Responses in Post-menopausal Women According to Administration Route
The aim of this pilot study conducted in post-menopausal women is to evaluate the effect of 17ß-estradiol administration on inflammatory-immune cells, namely antigen-presenting cells (monocytes/dendritic cells), and more…
- Trial name
- NCT00701337
- Testing
- oestradiol
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Toulouse
Backache, Low
Core Muscle Stability on Low Back Pain and Quality of Life in Post- Menopausal Women
Low back pain, postural dysfunction, loss of balance control and stability are musculoskeletal changes that occur over life span due to aging process and are inevitable.
- Trial name
- NCT03902132
- Testing
- Core Stability exercises group, Traditional low back physical therapy group
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riphah International University