Clinical trials: Post Operative Pain After Hip Arthroplasty
Total Hip Arthroplasty (THA), Postoperative Pain Management After Total Hip Arthroplasty
MRI-Based Assessment of Local Anesthetic Spread in the PENG Block Compartment
This study uses MRI imaging to evaluate the spread of local anesthetic following the administration of a pericapsular nerve group (PENG) block.
- Trial name
- MRI-PENG (NCT07040423)
- Testing
- PENG Block, Magnetic resonance imaging
- Where
- Italy
- Volunteers
- 6 people
- Sponsor
- Campus Bio-Medico University
Arthroscopic Knee Repair, Arthroscopic Hip Repair
PO Methadone Ortho Outpatient
The goal of this clinical trial is to learn if oral methadone given before surgery works to minimize post-operative pain and opioid usage.
- Trial name
- NCT06351215
- Testing
- Methadone group
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Keck School of Medicine of USC
Pain, Postoperative, Ropivacaine
Effect of Nervus Cutaneous Femoris Lateralis-Blockade on Moderate Pain Responders After Total Hip Arthroplasty
The patients will be included the 1. or 2. day after surgery. All THA patients will be screened. Those reporting VAS > 40 during active 30 degrees hip flexion will be asked to participate.
- Conditions
- Pain, Postoperative, Ropivacaine, Therapeutic Use, Arthroplasty, Replacement, Hip
- Trial name
- NCT02344264
- Testing
- Ropivacaine, Saline
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Daniel Hägi-Pedersen
Total Hip Arthroplasty
Continuous L2 Paravertebral Block Versus Continuous Lumbar Plexus Block for Postoperative Analgesia
This prospective study is intended to compare the analgesic efficacy, preservation of lower extremity motor power and side-effect profile of L2 Paravertebral lumbar plexus approach compared to Posterior nerve stimulation guided…
- Trial name
- NCT01571492
- Testing
- L2 Paravertebral catheter nerve block, Continuous Lumbar plexus nerve block
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
Regional Anaesthesia
QLESP Block Versus Periarticular Infiltration for Postoperative Analgesia in Hip Surgery
Local and/or regional analgesia techniques are critical components of an optimal multimodal analgesia technique, as they have been shown to improve pain relief as well as reduce opioid requirements.
- Trial name
- NCT06688136
- Testing
- ropivacaine
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Huazhong University of Science and Technology
Pain, Postoperative, Opioid Overdose
Ultrasound-guided PENG Block in Total Hip Replacement
This randomized controlled study will be carried out on 60 adult patients undergoing primary total hip replacement in Tanta University Hospitals.
- Trial name
- NCT04984109
- Testing
- Real PENG block
- Where
- Egypt
- Volunteers
- 71 people
- Sponsor
- Tanta University
Post-operative Pain, Total Hip Arthroplasty (THA)
Ultrasound Guided Lumbar Erector Spinae Block Using Bupivacaine - Magnesium Sulphate Versus Bupivacaine - Dexamethasone in Total Hip Replacement Surgery
The current study was done to evaluate the effect of adding dexamethasone and magnesium sulfate to bupivacaine as adjuvants in an ultrasound-guided erector spinae block for patients undergoing total hip arthroplasty (THA), and to…
- Conditions
- Post-operative Pain, Total Hip Arthroplasty (THA), Erector Spinae Plane Block
- Trial name
- NCT07418671
- Testing
- Bupivacaine-Magnesium Sulphate, Bupivacaine-Dexamethasone, Bupivacaine-Saline
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Ain Shams University
Perioperative Analgesia, Hip Replacement, Total
Pericapsular Nerve Group Block Versus Intrathecal Morphine for Analgesia After Total Hip Arthroplasty
The Pericapsular Nerve Group (PENG) block is an effective method for postoperative pain management in patients undergoing primary total hip arthroplasty (THA) via a posterolateral approach.
- Conditions
- Perioperative Analgesia, Hip Replacement, Total, Postoperative Pain, Hip Disease
- Trial name
- NCT07449585
- Testing
- PNEG block, Spinal anesthesia with opioid, Spinal anesthesia without opioid
- Volunteers
- 180 people
- Sponsor
- Medical University of Gdansk
Pain Management, Total Hip Arthroplasty
Ultrasound-Guided Quadro-Iliac Plane Block for Pain Management After Total Hip Arthroplasty
This prospective, randomized, double-blind study evaluates the analgesic effectiveness of the ultrasound-guided Quadro-Iliac Plane (QIP) block in patients undergoing primary total hip arthroplasty.
- Trial name
- NCT07410000
- Testing
- Quadro-Iliac Plane (QIP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bursa City Hospital
Virtual Reality, Hip Arthropathy
VR Effects After Hip Replacement Surgery Pain
Total Hip Arthroplasty (THA), a procedure performed to enhance the quality of life, is accompanied by postoperative challenges such as pain and anxiety that adversely affect patient comfort.
- Conditions
- Virtual Reality, Hip Arthropathy, Comfort, Anxiety
- Trial name
- THA (NCT07689461)
- Testing
- cognitive intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Adiyaman University
Post Operative Pain After Hip Arthroplasty
Pericapsular Nerve Group Block in Hip Arthroplasty
Peripheral nerve blocks are becoming increasingly popular for hip surgery anesthesia. Modern regional anesthesia for major hip surgery includes the use of a single shot and continuous epidural or spinal injections, continuous…
- Trial name
- NCT04336059
- Testing
- pericapsular nerve group block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Osteoarthrosis Patients With Total Hip Arthroplasty
Thigh Swelling, Hip-muscle Strength, and Functional Performance Following Total Hip Arthroplasty
By this study the investigators wish to (1) quantify hip strength and functional-performance deficits at discharge after fast-track total hip arthroplasty (THA), and (2) investigate if changes in thigh circumferences, or hip pain…
- Trial name
- THA (NCT01246674)
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Hvidovre University Hospital
Total Hip Arthroplasty, Postoperative Pain
PENG, Suprainguinal Fascia Iliaca Block, and Control After Total Hip Arthroplasty
Total hip arthroplasty can cause significant pain after surgery. Regional anesthesia techniques, such as the pericapsular nerve group (PENG) block and the suprainguinal fascia iliaca plane block, may help reduce postoperative…
- Trial name
- NCT07879521
- Testing
- Pericapsular nerve group (PENG) block, Suprainguinal Fascia Iliaca Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Uludag University
Postoperative Bleeding
Tranexamic Acid Use on Pain, Mobility and Bleeding Following Total Hip and Total Knee Arthroplasty
Tranexamic acid (TXA) is an anti-fibrinolytic agent developed in the 1960s that has been safely used to reduce blood loss, transfusion rates and bleeding-associated mortality in trauma, obstetrics and orthopedic surgery…
- Trial name
- TXA (NCT06208267)
- Testing
- Tranexamic acid
- Where
- Canada
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- St. Mary's Research Center, Canada
Total Hip Arthroplasty
Efficacy of Intravenous Oxytocin to Speed Recovery After THA
The purpose of this study is to test whether perioperative intravenous (IV) oxytocin compared to placebo results in faster recovery in disability as measured by daily steps over 56 days after Total Hip Arthroplasty (THA).
- Trial name
- NCT07430228
- Testing
- intravenous administration of oxytocin
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Wake Forest University Health Sciences
Hip Arthroplasty
Effect of Spinal Ketorolac on Mechanical Hypersensitivity After a Total Hip Replacement
Chronic pain in patients following total hip replacement seems to be a significant problem. Previous research has shown that more effective pain management in the early postoperative period may decrease the incidence of the…
- Trial name
- NCT00621530
- Testing
- ketorolac tromethamine opthalmic solution
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- Wake Forest University
Persistent Postsurgical Pain, Arthritis Knee
Weight Change and the Risk of Chronic Pain Following Hip and Knee Arthroplasties
The study is a nationwide, register-based cohort survey study. The objective of this study is to investigate whether weight change is associated with the incidence of persistent postoperative pain following total hip arthroplasty…
- Conditions
- Persistent Postsurgical Pain, Arthritis Knee, Arthropathy of Knee, Arthropathy of Hip
- Trial name
- NCT06024161
- Testing
- Weight gain, Weight loss, Weight unchanged
- Volunteers
- 6,400 people
- Sponsor
- Bispebjerg Hospital
Post-Operative Pain
Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Postoperative Pain Following Total Hip Arthroplasty.
The purpose of this phase 2 study is to evaluate the efficacy and safety of an analgesic drug candidate, VVZ-149 Injections. The study is designed as randomized, double-blind, parallel, and placebo-controlled study.
- Trial name
- NCT03347266
- Testing
- VVZ-149 injections
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Vivozon, Inc.
Pain, Postoperative, Hip Osteoarthritis
The Effect of Wrist Ankle Acupuncture on Post-Total Hip Arthroplasty Pain
Total hip arthroplasty is one of the most cost-effective orthopedic surgical procedures which can restore hip function and improve the patient's quality of life.
- Conditions
- Pain, Postoperative, Hip Osteoarthritis, Hip Fractures, Hip Injuries
- Trial name
- NCT06380439
- Testing
- wrist ankle acupuncture
- Where
- 3 sites in Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Postoperative Pain
PENG Block Versus Intrathecal Morphine for Early Postoperative Recovery After Total Hip Arthroplasty
The goal of this clinical trial is to compare the PENG block with intrathecal morphine for early postoperative recovery and pain control in adults undergoing elective total hip arthroplasty.
- Trial name
- NCT07803133
- Testing
- Pericapsular nerve group (PENG) block, Intrathecal Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Erzincan Binali Yildirim Universitesi