Clinical trials: Post-Acute COVID19 Syndrome
Long COVID, Distress Tolerance
Long COVID-19 Intervention Using Digital Health & Technology
The current study seeks to pilot test the iENDURE (Enhancing Distress tolerance to Uplift motivation in Recovery) intervention among 10 participants with Long COVID (Coronavirus Disease) symptoms.
- Trial name
- LIGHT (NCT05616806)
- Testing
- iENDURE
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Long COVID, Post-COVID-19 Condition
A Study of Human Umbilical Cord Blood (REGENECYTE) Infusion in Patients With Post-COVID Condition
REGENECYTE (HPC, Cord Blood) for treatment in patients with post-COVID.
- Conditions
- Long COVID, Post-COVID-19 Condition, Post-COVID Syndrome, Post-COVID Condition
- Trial name
- NCT07184385
- Testing
- REGENECYTE
- Volunteers
- 60 people
- Sponsor
- StemCyte, Inc.
Long COVID
Cognitive Rehabilitation for Long COVID
The investigators are comparing two different methods for helping adults with Long Coronavirus (COVID) also known as Post-Coronavirus Syndrome or Post-Coronavirus Condition manage everyday cognitive challenges.
- Trial name
- STAR-C3 (NCT05676047)
- Testing
- Cognitive Rehabilitation, Education
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Long COVID, Long Covid19
RECOVER-ENERGIZE Platform Protocol
This is a platform protocol designed to be flexible so that it is suitable for a range of interventions and settings within diverse health care systems and community settings with incorporation into clinical COVID-19 management…
- Conditions
- Long COVID, Long Covid19, Long Covid-19
- Trial name
- NCT06404047
- Testing
- Personalized Cardiopulmonary Rehabilitation, Structured Pacing, Education
- Where
- 42 sites in United States
- Volunteers
- 660 people
- Sponsor
- Duke University
Long-COVID, Post-acute COVID-19 Syndrome
Effectiveness of Non-invasive Neuromodulation in Patients With Long-COVID
Sleep quality and duration are critical to cognitive, emotional and physical well-being, and poor sleep quality has been associated with an increased risk of cognitive, psychological and cardiometabolic disorders.
- Trial name
- NCT06456502
- Testing
- Non-invasive neuromodulation
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Universidad Rey Juan Carlos
Long COVID, Dysautonomia
Mindfulness in Post Acute Sequelae of SARS-CoV-2 Infection (PASC) Dysautonomia
The current pilot study will recruit participants experiencing new, returning, or ongoing symptoms related to COVID-19 illness for at least four weeks after being first infected with SARS-CoV-2.
- Trial name
- NCT05566379
- Testing
- Mindfulness - Mindful Awareness Practices ( MAPs)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Long COVID, Major Depressive Disorder
Presynaptic Imaging in Major Depressive Episodes After COVID-19
The goal of this observational study focuses on understanding and addressing a subset of persistent neuropsychiatric symptoms occurring within 3 months after mild to moderate COVID-19 infection (COVID-DNP).
- Conditions
- Long COVID, Major Depressive Disorder, Major Depressive Episode
- Trial name
- PCOV (NCT06086366)
- Testing
- [11C]DTBZ PET scan, [18F]SDM8 PET scan, MRI scan
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Lung Fibrosis Interstitial, Post-COVID-19 Syndrome
Effect of Aerobic Exercises Versus Incentive Spirometer Device on Post-covid Pulmonary Fibrosis Patients
the aim of this study will be to investigate the effect of aerobic exercises vs incentive spirometer device on post-covid patients with residual lung diseases.
- Trial name
- NCT06191367
- Testing
- Aerobic Exercises, Incentive Spirometer Device, Traditional Chest Physiotherapy
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- McCarious Nahad Aziz Abdelshaheed Stephens
COVID-19
COVID-19: A Prevalence Study of Two ART Centres After the Pandemic Lockdown in the USA (COVID-19 Free Clinics)
In late December 2019, a new coronavirus strain emerged causing coronavirus disease 2019 (COVID19). Since then, COVID19 has become a global pandemic outbreak being declared a "public health emergency of international concern" by…
- Trial name
- NCT04466644
- Testing
- ELISA, RT-PCR
- Where
- 2 sites in United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Igenomix
Long COVID
The Impact of Chiropractic on Long COVID-19
The purpose of this waitlist-controlled, single-blind, one-way crossover, pilot trial is to evaluate the potential effects of ~8 weeks of chiropractic care on patient-reported fatigue and the autonomic nervous system in adults…
- Trial name
- NCT05693064
- Testing
- wait-list, chiropractic adjustments
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Life University
SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis
Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center?
The primary objective of the present research is to determine the effectiveness of Family Health Center of San Diego's Long COVID and Fatiguing Illness Recovery Program (LC\&FIRP) on clinician- and patient-level outcomes.
- Conditions
- SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, Post-acute Sequelae of SARS-COV-2 Infection
- Trial name
- LC&FIRP (NCT05167227)
- Testing
- Extension for Community Healthcare Outcomes
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Family Health Centers of San Diego
Post-COVID-19 Syndrome
Temelimab as a Disease Modifying Therapy in Patients With Neuropsychiatric Symptoms in Post-COVID 19 or PASC Syndrome
This study is a Phase 2, 24-week, randomized, prospective, double-blind, multicenter study in patients experiencing neuropsychiatric symptoms and functional impairment in the course of PASC.
- Trial name
- NCT05497089
- Testing
- Temelimab 54mg/kg
- Where
- 14 sites in Italy, Spain and 1 more
- Volunteers
- 203 people
- Sponsor
- GeNeuro SA
Severe COVID-19
Impact of Post-ARDS Covid-19 Sedation on Persistent Neuroinflammation
ICU Patients admitted after ARDS due to COVID infection should be weaned from invasive mechanical ventilation as quickly as possible.
- Trial name
- PET-DEXDOCOVID (NCT05233605)
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Long COVID, Chronic Pain
Characterization of Long Covid Pain in Primary Care
Justification: among the sequelae of Covid-19 in clinical practice we frequently find persistent neuromusculoskeletal pain. Prevalence data and the underlying mechanisms of such pain are very limited in the scientific literature.
- Conditions
- Long COVID, Chronic Pain, Musculoskeletal Pain
- Trial name
- NCT05894642
- Testing
- 0
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
COVID-19, Long Covid
"Long COVID-19" on the Human Brain
Over one million Canadians have been infected by COVID-19. Many people who have been infected by COVID-19 experience negative mental symptoms, such as "brain fog" and fatigue.
- Conditions
- COVID-19, Long Covid, Post Acute Sequelae of COVID-19
- Trial name
- NCT05433324
- Testing
- MRI and PET Scans
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
COVID-19
Long Covid After COVID-19 Infection With Omicron Variant
The COVID-19 pandemic has led to a high disease burden worldwide, both during the acute disease phase and a large group of infected suffering from Long Covid.
- Trial name
- NCT05234294
- Testing
- Survey
- Where
- Faroe Islands
- Volunteers
- 15,000 people
- Sponsor
- Faroese Hospital System
Long-COVID, Post COVID-19 Condition
Sulfureous Water Therapy in Viral Respiratory Diseases
The goal of this double-blind, interventional, randomized case-control, pilot trial is to evaluate the effects of active sulfurous (STW) versus placebo (SDW) inhalations on blood test parameters, serum inflammatory cytokines…
- Conditions
- Long-COVID, Post COVID-19 Condition, Chronic COVID-19 Syndrome, Post Acute Sequelae of COVID-19
- Trial name
- STWandRVD (NCT06294756)
- Testing
- Inhalation of Sulfurous Thermal Water, Inhalation of Sterile Distilled non-pyrogenic Water
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Roma La Sapienza
Long Covid19, Dietary Supplements
IMMUNERECOV CONTRIBUTES TO IMPROVEMENT OF RESPIRATORY AND IMMUNOLOGICAL RESPONSE IN POST-COVID-19 PATIENTS.
Background: COVID-19 left consequences in different organs from months to years requiring different types of rehabilitation. In fact, a severe loss in the lung function, and in the respiratory and peripheral muscle strength is…
- Conditions
- Long Covid19, Dietary Supplements, Respiratory Tract Infections, Inflammation
- Trial name
- IRPC (NCT06166030)
- Testing
- Nutritional blend (ImmuneRecov).
- Where
- 2 sites in Brazil
- Volunteers
- 58 people
- Sponsor
- Federal University of São Paulo
Long COVID, Post-COVID Conditions
Transcranial Direct Current Stimulation for Long COVID Brain Fog and Fatigue
Long COVID can cause persistent symptoms such as fatigue, cognitive difficulties commonly described as brain fog, reduced exercise tolerance, and impaired quality of life.
- Conditions
- Long COVID, Post-COVID Conditions, Fatigue, Cognitive Dysfunction
- Trial name
- NEUROSTIM-LC (NCT07709234)
- Testing
- Transcranial Direct Current Stimulation
- Volunteers
- 20 people
- Sponsor
- University of Las Palmas de Gran Canaria
COVID-19, COVID Long
Burden of Care of Long COVID Patients After Hospital Discharge
Since March 2020, 3.5 million people have been infected with SARS-COV2 in France, and about 250 000 patients have been hospitalized and successfully discharged.
- Trial name
- BLOC (NCT05073328)
- Testing
- COVID-19 required hospitalisation
- Where
- France
- Volunteers
- 68,822 people
- Sponsor
- Mikhail Dziadzko, MD, PhD