Clinical trials: Post-Operative Prostate Cancer
Postoperative Delirium (POD), Prostate Cancer
A Phase II Clinical Two-Stage Study of Transcranial Magnetic Stimulation in Preventing Postoperative Delirium in Elderly Patients After Urological Surgery
Cases were included based on the inclusion and exclusion criteria, and induction, maintenance, and recovery were conducted in accordance with the standard protocol for general anesthesia.
- Conditions
- Postoperative Delirium (POD), Prostate Cancer, Kidney Tumor
- Trial name
- NCT07480044
- Testing
- Transcranial Magnetic Stimulation Device
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Zhejiang University
Prostate Cancer
Salvage Radiotherapy After Radical Prostatectomy
The purpose of this study is to describe the urinary morbidity as a result surgery and radiation therapy, in patients treated for prostate cancer.
- Trial name
- SRT (NCT02597725)
- Volunteers
- 70 people
- Sponsor
- University of Aarhus
Post-Operative Prostate Cancer
Comparing Moderately and Ultra Hypofractionated Radiation Treatments for Post-operative Prostate Cancer
This is a multi-institution, randomized, non-inferiority Phase II trial comparing external beam radiotherapy delivered as 54 Gy in 20 fractions to prostate bed +/- 44 Gy in 20 fractions to pelvic lymph nodes delivered daily with…
- Trial name
- AMPORA (NCT06409910)
- Testing
- Radiotherapy
- Where
- 3 sites in Canada
- Volunteers
- 204 people
- Sponsor
- University Health Network, Toronto
Prostate Cancer, Anesthesia, Local
Open Radical Prostatectomy and Erector Spinae Plane Block
In the proposed study, a bilateral erector spinae plane (ESP) block [10 ml 1%lidocaine + 10 ml 0.5 % bupivacaine vs normal saline (NS)] will be performed preoperatively to patients undergoing open radical prostatectomy.
- Conditions
- Prostate Cancer, Anesthesia, Local, Pain, Postoperative
- Trial name
- NCT04337060
- Testing
- Single-injection ultrasound-guided bilateral erector spinae plane block-Lidocaine/Bupivacaine, Pain follow-up and monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- BURHAN DOST
Prostate Cancer
CoSMAP Trial: SP-EA vs MP-TA Robot-Assisted Radical Prostatectomy
This multicenter retrospective observational study aims to compare perioperative and postoperative outcomes between the da Vinci SP extraperitoneal approach (SP-EA) and the robotic multi-port transperitoneal approach (MP-TA) in…
- Trial name
- CoSMAP (NCT07666217)
- Where
- 8 sites in Japan
- Volunteers
- 625 people
- Sponsor
- Intuitive Surgical
Radical Prostatectomies, Rehabilitation Outcome
State of Play of Physiotherapy in the Postoperative Management of Prostate Cancer : Prospective, Monocentric, National Survey, Aiming to Explore the Technics of Physiotherapy (PREduKiné)
In France, a considerable number of radical prostactectomy for cancer is carried out every year.This number was estimated at 20.000 in 2016.This surgery may have negative impact on the continence's subjects and their quality of…
- Conditions
- Radical Prostatectomies, Rehabilitation Outcome, Prostate Cancer, Prostate Cancer Surgery
- Trial name
- PREduKiné (NCT06815055)
- Testing
- Quality of life questionnary
- Volunteers
- 510 people
- Sponsor
- Centre Hospitalier de Roubaix
Prostate Cancer, Robot-Assisted Laparoscopic Radical Prostatectomy
Enhanced Recovery After Surgery (ERAS) Pathway in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy
Prostate cancer ranks second among all malignances in men and has become a significant threat to men's health. Robot-assisted laparoscopic radical prostatectomy (RARP) has become a standard treatment for prostate cancer.
- Conditions
- Prostate Cancer, Robot-Assisted Laparoscopic Radical Prostatectomy, Enhanced Recovery After Surgery (ERAS) Protocol, Prehabilitation
- Trial name
- NCT05576766
- Testing
- Routine care, ERAS management pathway
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Peking University First Hospital
Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8
Conventional or Hypofractionated Radiation Therapy in Treating Patients With Prostate Cancer
This phase III trial studies how well hypofractionated radiation therapy works compared to the conventional one in treating patients with prostate cancer.
- Conditions
- Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8
- Trial name
- NCT03987386
- Testing
- Hypofractionated Radiation Therapy, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 3 sites in United States
- Volunteers
- 186 people
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer (CRPC)
Prostate Cancer Postoperative Stereotactic Body Radiotherapy With Adaptive Technology for Minimizing Toxicity
Single-arm, prospective registry study assessing changes in acute patient-reported urinary (GU) and gastrointestinal (GI) quality of life at the 24-month post-treatment time point following magnetic resonance imaging (MRI)-guided…
- Trial name
- MASAMUNE (NCT07077239)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Men With Prostate Cancer Undergoing Robot Assisted Radical Prostatectomy
A Study of Intra-operative Autologous Retropubic Urethral Sling on Urinary Control After Robot Assisted Radical Prostatectomy
Placement of an autologous retropubic urethral sling at the time of robot assisted radical prostatectomy will improve the recovery of continence after radical prostatectomy
- Trial name
- Sling (NCT01821209)
- Testing
- Placement of sling
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- University of California, San Francisco
Low Anterior Resection Syndrome, Malignant Anal Neoplasm
Sacral Nerve Stimulation in Treating Low Anterior Resection Syndrome or Fecal Incontinence in Patients With Locally Advanced Rectal Cancer or Other Pelvic Cancer, the RESTORE Study
This phase II trial studies how well sacral nerve stimulation works in treating low anterior resection syndrome or fecal incontinence (the body's passage of stool without control) in patients with rectal cancer that has spread to…
- Conditions
- Low Anterior Resection Syndrome, Malignant Anal Neoplasm, Malignant Bladder Neoplasm, Malignant Cervical Neoplasm
- Trial name
- NCT04066894
- Testing
- Explantation, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
Prostatic Neoplasms, Urinary Incontinence
Preservation of Endopelvic Fascia: Effects on Postoperative Incontinence and Impotence. Randomized Clinical Trial.
Urinary incontinence and impotence are typical disturbances after radical prostatectomy. Although, several surgical methods are developed to decrease these disturbances, 8% and 50% of the patients suffer from permanent urinary…
- Conditions
- Prostatic Neoplasms, Urinary Incontinence, Erectile Dysfunction
- Trial name
- NCT02526602
- Testing
- Preservation (endopelvic fascia), Opening (endopelvic fascia)
- Where
- Finland
- Volunteers
- 158 people
- Sponsor
- Tampere University Hospital
Prostate Cancer, Renal Cancer
HPI Effect in Robotic Urological Surgery on AKI
It is a single-center randomized controlled trial that aims to figure out the effect of the hypotension prediction index (HPI) on the prevention of acute kidney injury (AKI) after robot-assisted urological surgery.
- Conditions
- Prostate Cancer, Renal Cancer, Urologic Diseases
- Trial name
- NCT06051162
- Testing
- BP management with HPI guidance
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Ewha Womans University Mokdong Hospital
Prostate Cancer
Multi-site Decision Impact Study for Decipher
This prospectively designed retrospective clinical utility study will evaluate urologists' treatment recommendations before and after reviewing Decipher results for selected patient cases.
- Trial name
- ASSESS-D (NCT02034825)
- Testing
- Decipher Questionnaire
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- GenomeDx Biosciences Corp
Urologic Cancer, Prostate
Comparison of the Integrated Posterior-Anterior-Lateral Approach and the Posterior Approach in Robotic Radical Prostatectomy
This study aims to compare perioperative, pathological, and early functional outcomes of PAL （Posterior, Anterior and Lateral）combined approach RARP and posterior approach (with Retzius space preserved) RARP in the treatment of…
- Conditions
- Urologic Cancer, Prostate, Robot Assisted Laparoscopic Radical Prostatectomy
- Trial name
- NCT07305142
- Testing
- PAL combined approach group, posterior approach group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Prostate Cancer
Multicenter Study of Hypofractionated Postoperative Radiotherapy in Patients Diagnosed With Prostate Carcinoma
The objective of this study is to evaluate, in patients diagnosed with prostate cancer who undergo radical prostatectomy and who require postoperative radiotherapy, tolerance in terms of acute and chronic GU and GI toxicity and…
- Trial name
- NCT04484038
- Testing
- hypofractionated postoperative radiation therapy
- Where
- 19 sites in Spain
- Volunteers
- 300 people
- Sponsor
- Grupo de Investigación Clínica en Oncología Radioterapia
Prostate Cancer
Postop Hypofractionated Radiation Therapy and LHRH in Patients With Prostate Cancer
Prostate cancer is the second most common cancer among Canadian men of which approximately 20-30% present with high-risk tumour characteristic.
- Trial name
- PROMPT (NCT04249154)
- Testing
- Eligard
- Where
- 2 sites in Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Lymphocele, Prostate Cancer
Microspheres in Preventing Lymphatic Fluid Collection After Surgery in Patients With Prostate Cancer
This study is being performed to investigate if the application of Arista absorbable hemostat (AH)®, a product approved to stop surgical bleeding, can prevent lymphoceles.
- Trial name
- NCT01644136
- Testing
- robot-assisted laparoscopic surgery, regional lymph node dissection, microsphere-mediated lymphocele prevention
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Robot-Assisted Radical Prostatectomy, Prostatic Neoplasms
Effect of Changes in Endotracheal Tube Cuff Pressure on Postoperative Pharyngolaryngeal Complications in Robotic Surgery
The goal of this observational study is to evaluate how changes in endotracheal tube (ETT) cuff pressure during robot-assisted radical prostatectomy (RARP) affect postoperative throat-related symptoms.
- Trial name
- NCT07242144
- Testing
- Continuous Monitoring of Endotracheal Tube Cuff Pressure
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ege University
Prostate Carcinoma
Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With High-Risk Prostate Cancer, The ERADICATE Study
This phase III trial compares the effect of adding darolutamide to ADT versus ADT alone after surgery for the treatment of high-risk prostate cancer. ADT reduces testosterone levels in the blood.
- Trial name
- NCT04484818
- Testing
- Darolutamide, Goserelin Acetate, Leuprolide Acetate
- Where
- 115 sites in United States
- Volunteers
- 27 people
- Sponsor
- ECOG-ACRIN Cancer Research Group