Clinical trials: Post-acne Atrophic Scars
Atrophic Acne Scar
Fractional CO₂ Laser Combined With Topical Plant-Derived Exosomes Versus Non-Cross-Linked Hyaluronic Acid for Atrophic Acne Scars
Fractional CO₂ laser combined with topical exosomes and non-cross-linked hyaluronic acid both improve atrophic acne scars, but direct comparative evidence between these adjunctive therapies has been limited.
- Trial name
- NCT07868445
- Testing
- Fractional co2 laser, Exosomes, Hyaluronic Acid skin booster
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Atrophic Acne Scar
Phenytoin in Treatment of Atrophic Post Acne Scars.
To evaluate the efficacy and safety of topical phenytoin spanlastics as an adjuvant therapy in treatment of atrophic post acne scars.
- Trial name
- NCT06942468
- Testing
- Topical nano preparation of Phenytoin, Fractional CO2 laser
- Volunteers
- 30 people
- Sponsor
- Assiut University
Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars
Evaluation of Efficacy and Safety of HCC_45 for the Correction of Acne Scars of the Face
Acne scars represent a frequent complication of moderate/severe acne and may negatively impact on psychosocial and physical well-being of acne patients.
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars, Rolling Scars, Boxcar Scars
- Trial name
- NCT05691049
- Testing
- HCC_45
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IBSA Farmaceutici Italia Srl
Post-Acne Atrophic Scars, Carbon Dioxide Lasers
PRP Plus Fractional CO₂ Laser for Acne Scars
This randomized controlled trial aims to evaluate whether adding platelet-rich plasma (PRP) to fractional CO₂ laser resurfacing improves the treatment of moderate-to-severe acne scars compared with laser alone.
- Conditions
- Post-Acne Atrophic Scars, Carbon Dioxide Lasers, Platelet-Rich Plasma
- Trial name
- PRPLT (NCT07352215)
- Testing
- Fractional CO₂ Laser + Platelet-Rich Plasma (PRP), Fractional CO₂ Laser Only
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Gujranwala medical college District Headquarters Hospital, Gujranwala
Acne Scars - Atrophic
Comparative Study of The Efficacy and Safety of Subcision Combined With Injection of Exosomes Versus Subcision Alone in Treatment of Atrophic Post- Acne Scars.
This split-face comparative prospective study was carried out on 20 patients presenting with atrophic post-acne scars. All participants were subjected to full history taking, general and dermatological examination, photographing…
- Trial name
- NCT07906509
- Testing
- Subcision plus exosome injection, Subcision
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Atrophic Acne Scar
Combined LASERs and PRP for Postacne Scars
This study evaluates a new combined technique using two different laser wavelengths and Platelets Rich Plasma (PRP) to treat post-atrophic acne scars.
- Trial name
- NCT03809416
- Testing
- Lasers, Platelets Rich Plasma, Lasers plus Normal Saline Solution
- Where
- 2 sites in Italy, Kuwait
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- DEKA S.r.l.
Acne Scars - Atrophic
Stromal Vascular Fraction Enriched PRP in Treatment of Post-acne Scars
in a split face fashion, 30 patients will be randomized into 3 groups: Group A: rt side treated with SVF enriched PRP, lt side treated with prp Group B: rt side treated with SVF enriched PRP, lt side treated with SVF Group C: rt…
- Trial name
- NCT06524011
- Testing
- Stromal vascular fraction (SVF) enriched platelet rich plasma (PRP) versus each alone
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Acne Scars - Mixed Atrophic and Hypertrophic
Microneedling With Topical Preparations in the Treatment of Atrophic Post-acne Scars
To examine the anti-scarring effect of topical glycolic acid 35% combined with microneedling against that of topical insulin combined with microneedling for post acne scars
- Trial name
- NCT05600075
- Testing
- microneedling with topical glycolic acid 35%., microneedling with topical human insulin solution.
- Volunteers
- 30 people
- Sponsor
- Zagazig University
Atrophic Post Acne Scarring
Comparison Between Microneedling Daycare Procedure and Tazarotene 0.1% Gel Local Application in Acne Scarring
Post acne scarring is a common complication of acne. Cosmetic appearance of the post acne facial scarring can be improved by various methods. Among the procedural methods microneedling (1) is a novel and a promising option.
- Trial name
- NCT03170596
- Testing
- tazarotene gel 0.1%, Microneedling
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Post-acne Atrophic Scars
Comparison of Efficacy of Microneedling With Platelet Rich Plasma Vs Microneedling With Topical Insulin in the Treatment of Acne Scars
This study compares the outcome of two procedures for the treatment of atrophic acne scars.
- Trial name
- NCT06978361
- Testing
- Microneedling with autologous Platelet Rich Plasma, Microneedling with topical insulin
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- Khyber Teaching Hospital
Atrophic Scar
Clinical Benefits and Safety of Combined Polynucleotides and Hyaluronic Acid - Newest - for Acne Scars Treatment
This clinical study wants to evaluate the efficacy and safety of a medical device combining "Polynucleotide Highly Purified Technology" (PN-HPT™) and hyaluronic acid (Newest-Mastelli S.r.l) for treating moderate-to-severe…
- Trial name
- NCT05936437
- Testing
- Subjects treated with Newest medical device
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Mastelli S.r.l
Acne Scars - Mixed Atrophic and Hypertrophic
Early Non-Ablative Fractional Laser Resurfacing for Acne Scars After Treatment With Oral Isotretinoin
Patients who have completed have completed a cumulative dose of >=120miligram/kilogram oral isotretinoin within the last 30 days, and has mild to moderate acne scarring will be randomized, into a right-left comparison study using…
- Trial name
- NCT03514771
- Testing
- Fraxel DUAL 1550/1927, oral isotretinoin, oral valacyclovir
- Volunteers
- 15 people
- Sponsor
- David Smart
Atrophic Acne Scar
Simultaneous Versus Sequential Fractional CO2 Laser and Subcision Combination for Post-acne Atrophic Scars: A Split-face Comparative Study.
Acne vulgaris, a disease of the pilosebaceous unit, is estimated to afflict 9.4% of the global population, making it the eighth most prevalent and third most significant disease according to the global burden of disease.
- Trial name
- NCT05688202
- Testing
- Simultaneous combination of fractional CO2 laser and subcision, Sequential combination of fractional CO2 laser and subcision, Fractional CO2 laser
- Where
- Vietnam
- Volunteers
- 34 people
- Sponsor
- Ho Chi Minh City Hospital of Dermato-Venereology
Atrophic Acne Scar
Subcision With CO₂ Laser or PRP vs Subcision Alone in Atrophic Acne Scars
Acne vulgaris is an inflammatory disease of pilosebaceous unit ,leading to different types of scars including atrophic, hypertrophic and keloidal.
- Trial name
- NCT07199608
- Testing
- subcision, subcision+fractional co2 laser, subcision+PRP
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Assiut University
Acne Atrophica, PRP
Poly-L-Lactic Acid Threads Versus Platelet-Rich Plasma for Post-Traumatic Atrophic Scars
This study compares the efficacy and safety of poly-L-lactic acid (PLLA) threads versus platelet-rich plasma (PRP), both combined with subcision, in the treatment of post-traumatic atrophic scars.
- Trial name
- PLLA-PRP PTAS (NCT07775092)
- Testing
- subcision and PLLA threads' insertion, PRP and subcision (PRP-S)
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Tanta University
Acne Scar
Comparing the Efficacy of Topical Tazarotene Gel 0.1% v/s Microneedling in Atrophic Post Acne Scars
The purpose of this study was to compare the Efficacy of Topical Tazarotene gel 0.1% versus Microneedling in atrophic Post acne scars.
- Trial name
- NCT05573425
- Testing
- Tazarotene gel 0.1%, Microneedling
- Where
- Pakistan
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Acne Scars - Atrophic
Efficacy and Safety of Combined Nanofat Injection With Either Platelet Rich Fibrin or Microneedling Versus Nanofat Injection Alone in the Treatment of Facial Atrophic Post Acne Scars
To compare the efficacy and safety of combined nanofat injection with either platelet rich fibrin or microneedling versus nanofat injection alone in the treatment of facial atrophic post acne scars.
- Trial name
- NCT07471854
- Testing
- nanofat injecion, Platelet rich fibrin, Microneedling
- Volunteers
- 42 people
- Sponsor
- Assiut University
Acne Vulgaris
Fractional CO2 Laser Delivery of Topical Insulin Versus Platelet Rich Plasma in Treatment of Atrophic Post Acne Scars
compare the efficacy and safety of treating atrophic post acne scars with topical insulin versus Platelet rich Plasma PRP combined with fractional ablative Co2 laser
- Trial name
- NCT06590909
- Testing
- Fractional CO2 laser assisted PDT
- Volunteers
- 22 people
- Sponsor
- Assiut University
ATROPHIC ACNE SCARS
Comparison Of Outcome Of Microneedling With Autologous PRP Vs Microneedling With Topical Insulin In Treatment Of Post Acne Atrophic Scars.
Microneedling with topical INSULIN is a simple, effective tool for building body's new collagen layers and thus an alternative to all erosive techniques such as lasers, peels.
- Trial name
- NCT06002854
- Testing
- PRP( platelet rich plasma) and Insulin human
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Acne Vulgaris, Atrophic Acne Scar
Autologous Plasma Gel Injection Versus Polydioxanone Cog Threads Insertion for the Treatment of Atrophic Post-acne Scars: a Split-face
Both male and female patients, with atrophic acne scars All patients underwent one session of subcision before receiving: A: cog PDO threads on one side of the face (one session). B: plasma gel on the other side (one session).
- Trial name
- NCT06580691
- Testing
- Subcision plus Plasma gel injection Vs Subcision plus Cog PDO threads
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sameh Sarsik