Clinical trials: Post-menopause
Psychological Phenomena and Processes, Nutrition Physiological Phenomena
The Effects of Fiber on Appetite and Digestion Hormones
In this research study, investigators are interested in how certain dietary fibers in the diet affect certain hormones released from your intestine after eating and how these influence your appetite.
- Trial name
- FS (NCT01050101)
- Testing
- No fiber, Low GI high fiber viscous meal, Low GI high fiber non-viscous
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Obesity
Prevention of Obesity in Women Via Estradiol Regulation
The purpose of this study is to evaluate potential mechanisms by which estradiol deficiency accelerates fat gain and abdominal fat accumulation in women.
- Trial name
- POWER (NCT00687739)
- Testing
- leuprolide acetate, Estradiol Transdermal, progressive resistance exercise training
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hypoactive Sexual Desire Disorder
A Pharmacokinetic (PK) Study to Compare the Absorption of Two Formulations of Transdermal Testosterone Spray and Intrinsa®
The purpose of this study is to determine if the absorption of the testosterone spray is the same as the Intrinsa® Patch.
- Trial name
- NCT01096329
- Testing
- Testosterone Spray 5% and 1%, Intrinsa® Patch and Testosterone Spray 5%, Intrinsa® Patch and Testosterone Spray 1%
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Post-menopausal Women, Post-menopausal Status
Dairy Choline Bioavailability
The goal of this clinical trial is to find out if dairy is a good source of choline compared to eggs. The main questions it aims to answer are: How the body uses choline; and, What effect WPPC has on choline metabolism.
- Trial name
- NCT06902480
- Testing
- WPPC, Whole egg powder
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Osteoporosis, Postmenopausal Bone Loss
Mediterranean Diet for Post-menopausal Women: Effects on Bone Turnover
The investigators propose a 24 week clinical research trial (12 week observational period followed by 12 week MedSD intervention) with feasibility of diet adoption and markers of bone turnover as the primary outcomes.
- Trial name
- MedSD (NCT01653275)
- Testing
- Mediterranean Diet
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- UConn Health
Osteoporosis, Post-Menopausal
Combination Osteogenic Therapy in Established Osteoporosis
This study is designed to determine if combining parathyroid (PTH 1-34) with fluoride (MFPSR) therapy in a cyclic treatment regimen will: (1) produce a greater increase in bone density of the spine than would be produced by…
- Trial name
- NCT00018447
- Testing
- PTH 1-34, MFPSR-fluoride
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Postmenopause
AFTER: Altering Fat Through Estrogen and Raloxifene
The purpose of this study is to determine whether estrogens specifically promote a reduction in fat from abdominal regions during weight loss and/or prevent the accumulation of abdominal fat during weight gain.
- Trial name
- NCT00149604
- Testing
- conjugated estrogens, Raloxifene, exercise plus mild caloric restriction for weight loss
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Post Menopause
High Intensity Resistance Training In Postmenopausal Women (HIRT)
Menopause is defined as a permanent cessation of menstrual cycle for 12 months due to intrinsic diminution of ovarian oocytes among women in older age.
- Trial name
- HIRT (NCT05052749)
- Testing
- High Intensity Resistance Training (HIRT), Low-moderate Resistance Exercise Training
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Post Menopausal, Resistance Exercise
Feasibility of Lower-Body EMS Resistance Training in Postmenopausal Women
This pilot randomized controlled trial evaluates whether combining lower-body electrical muscle stimulation (EMS) with resistance training is feasible and beneficial for physically inactive postmenopausal women, who experience…
- Conditions
- Post Menopausal, Resistance Exercise, Body Composition, Autonomic Function
- Trial name
- LB-EMS-Pilot (NCT07628790)
- Testing
- Lower-Body EMS combined with Resistance Training, Resistance Training
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University
Bone Density, Osteopenia
The Influence of Vibration on Bone Mineral Density in Women Who Have Weak Bones After Menopause
This study will examine whether whole-body vibration slows down bone loss in healthy postmenopausal women with osteopenia. Whole-body vibration is a promising novel therapy that involves standing on a platform which produces…
- Conditions
- Bone Density, Osteopenia, Osteoporosis, Post-Menopause
- Trial name
- NCT00420940
- Testing
- Juvent 1000 Dynamic Motion Therapy (DMT) Platform
- Where
- Canada
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Sexual Dysfunction, Postmenopausal Symptoms
Examination of the Effects of Pelvic Floor Exercises on Vaginal and Sexual Health in Postmenopausal Women.
The purpose of this study; To investigate the effects of pelvic floor muscle exercises on vaginal and sexual health in postmenopausal women.
- Conditions
- Sexual Dysfunction, Postmenopausal Symptoms, Pelvic Floor Muscle Weakness
- Trial name
- NCT06294197
- Testing
- Pelvic Floor Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hatice Gulsah Kurne
Menopause, Depression
Brain Imaging Study in Menopausal Women With and Without Major Depressive Disorder
The purpose this study is to measure cortical gama-aminobutyric acid levels (GABA) levels in menopausal women with major depressive disorder and healthy subjects using nuclear magnetic resonance spectroscopy (MRS).
- Trial name
- NCT00626340
- Testing
- MDD diagnosis and Estrogen treatment, MDD diagnosis and Fluoxetine treatment, MDD diagnosis with both Estrogen and Fluoxetine treatment
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Breast Cancer
Monitoring of Breast Tissue Change Due to Hormone Replacement Therapy in Post-menopausal Women Using OBS
Hormone Replacement Therapy (HRT) is a double edged sword: it can alleviate the effects of menopause for a significant proportion of the female population, however for a smaller proportion, it will induce a significant increase…
- Trial name
- TiBS-HRT (NCT00797199)
- Where
- 2 sites in Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Osteoporosis in Post-menopausal Women
Bone Health in Postmenopausal Women: The Effect of Exercise With or Without Medication for Osteoporosis
Osteoporosis is a systemic bone disorder characterised by a reduced bone mass and structural deterioration, increasing the risk of fragility fractures, particularly in women post-menopause.
- Trial name
- BEAT-OP (NCT07267325)
- Testing
- EXERCISE TRAINING, Antiresorptive medication (routine clinical care)
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Osteoporosis, Osteoporotic Fracture of Vertebra
Development and Evaluation of an Exercise Intervention for Prevention of Vertebral Osteoporosis and Deformity in Postmenopausal Women
Osteoporotic fractures of the vertebrae (bones in the back) cause substantial pain and disability. Exercise could help to prevent these fractures by increasing bone strength and improving posture.
- Conditions
- Osteoporosis, Osteoporotic Fracture of Vertebra, Postural, Thoracic Kyphosis
- Trial name
- NCT04660825
- Testing
- A resistance band exercise programme, Control
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Perimenopausal Bone Loss
Natto Supplementation to Prevent Loss of Bone Mass in Women Immediately After Menopause
Study Objective: To determine whether Natto supplementation in women immediately after menopause might prevent severe bone loss Study population: Women 50 - 60 years, 1-5 years after menopause Study Design: Double-blind…
- Trial name
- NCT00290212
- Testing
- Natto capsules (food suppl.) cont. 360 microg. vit K2/day
- Where
- 2 sites in Norway
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Obesity, Menopause Hot Flashes
The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity
The purpose of this study is to determine the effect of tirzepatide on vasomotor symptoms and on measures of biological aging.
- Trial name
- NCT07218445
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Drug Toxicity
Phase I Clinical Study of Soy Isoflavones in Healthy, Post-Menopausal Women
The purpose of this research study is to examine the safety of specific soy components, known as isoflavones, and to find out what effects (good and bad) these components have on tissues that are sensitive to the hormone estrogen…
- Trial name
- NCT00491595
- Testing
- High Dose Soy isoflavones
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of North Carolina
Female Androgenetic Alopecia
The Use of 5mg Finasteride Versus 200mg Spironolactone and Topical 5% Minoxidil in Treating Postmenopausal Female Androgenetic Alopecia
The investigators propose to conduct a head-to-head, randomized clinical trial to compare the effectiveness of Minoxidil with Spironolactone and Finasteride in treating postmenopausal females with Androgenetic Alopecia (AGA).
- Trial name
- NCT02483195
- Testing
- 5% Minoxidil, 200mg Spironolactone, 5mg Finasteride
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Osteoporosis in Post-menopausal Women, Prevention
Development of a Wearable Device for Osteoporosis Prevention and Fracture Risk Reduction in Women
This project aims to determine the impact on bone health of: A lifestyle intervention promoting impact-based activities and physical activity for nine months. The same program enhanced with home-based strength training.
- Conditions
- Osteoporosis in Post-menopausal Women, Prevention, Exercise, Physical Activity
- Trial name
- Weapom (NCT06741956)
- Testing
- Weapom Lifestyle Intervention to measure bone impacts using a Fitbit Versa wearable device and the Weapom App.
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Seville