Clinical trials: Post-operative Pain Management
Intensive Care Unit, Cardiac Surgery
The Effect of Light Therapy on Post-Surgical Pain
Researchers aim to demonstrate that the use of phototherapy is feasible and may reduce acute postoperative pain based on recent literature.
- Trial name
- NCT05853731
- Testing
- Green light emitting diode, White light emitting diode
- Where
- United States
- Sponsor
- Mayo Clinic
Analgesia, Post Operative Pain
The Analgesic Efficacy of Vitamin B Complex in Critically Ill Obstetrics After Caesarean Section
We aim to investigate the value of vitamin B (B1, B6, B9, B12) on post-cesarean section analgesia in addition to the standard opioid-sparing multimodal regimen to achieve more robust analgesia with minimal side effects.
- Conditions
- Analgesia, Post Operative Pain, Cesarean Section
- Trial name
- NCT06446830
- Testing
- multimodal analgesia and vitamin B, standard multimodal analgesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Heart Surgery Via Sternotomy, Post-operative Analgesia
Advantage of Tramadol in Local Analgesia Post-Sternotomy
Sternotomy, the reference approach for heart surgery, may induce profound and intense post-operative pain. One method of analgesia used is patient-controlled intravenous morphine.
- Trial name
- ATLAS (NCT02851394)
- Testing
- Levobupivacaine, tramadol
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Postoperative Pain Management
Ultrasound-Guided Erector Spinae Plane Block Versus Intravenous Nalbuphine
2.1. Study population and setting: This prospective, randomized, controlled clinical trial will be conducted at the thoracic surgery operation room, cardiothoracic surgery building, Zagazig University Hospitals, from July 2025 to…
- Trial name
- VATS (NCT07391475)
- Testing
- Erector Spinae (ESP) Block with Bupivacaine (Marcaine®)
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Zagazig University
Uniportal-VATS, Lung Resection Procedures
Serratus Posterior Superior Intercostal Plane (SPSIP) Block Versus Intercostal Nerve (ICN) Block in Patients Undergoing Uniportal-VATS.
This study aims to assess the effectiveness of the Serratus Posterior Superior Intercostal Plane (SPSIP) block compared to the Intercostal Nerve (ICN) block for postoperative pain control, reduction of opioid analgesic…
- Conditions
- Uniportal-VATS, Lung Resection Procedures, Locoregional Anesthesia, Post-operative Pain Management
- Trial name
- SPUV (NCT07250373)
- Testing
- SPSIP block, ICN block
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lower Extremities Fracture
Comparison Between Dexamethasone and Morphine as an Adjuvant to Bupivacaine for Post-operative Analgesia
The study aimed to compare the effectivity of dexamethasone 8 mg and morphine 2 mg as an adjuvant to epidural bupivacaine 0,125% 12,5mg for post-operative analgesia in lower extremities.
- Trial name
- NCT03051022
- Testing
- Dexamethasone 8 mg, Morphine 2 mg
- Where
- Indonesia
- Volunteers
- 64 people
- Sponsor
- Universitas Indonesia
Postoperative Pain, Postoperative Analgesia
A Predictive Model for Postoperative Analgesic Requirements After Abdominal Surgery
Postoperative pain remains a common challenge after abdominal surgery despite the use of standard multimodal pain management strategies.
- Conditions
- Postoperative Pain, Postoperative Analgesia, Opioid Analgesic Requirement, Pain Management After Abdominal Surgery
- Trial name
- NCT07803575
- Testing
- Intravenous Morphine Patient-Controlled Analgesia
- Where
- Malaysia
- Volunteers
- 65 people
- Sponsor
- Chaw Sook Hui
Total Knee Arthroplasty
Local Infiltration Analgesia Versus Quadruple Nerve Blocks in Total Knee Arthroplasty.
Total knee arthroplasty (TKA) is one of the most common orthopedic surgical procedures and is associated with severe pain in the immediate postoperative period, thus limiting early recovery.
- Trial name
- LIAQ (NCT07477730)
- Testing
- Surgical local infiltration, Obturator nerve block, Femoral nerve block
- Where
- France
- Volunteers
- 80 people
- Sponsor
- CMC Ambroise Paré
Coronary Artery Bypass Graft Surgery(CABG), Postoperative Pain Management
VR During Chest Tube Removal After CABG
The purpose of this randomized controlled clinical trial was to investigate whether virtual reality (VR) could reduce pain and anxiety during chest tube removal in adult patients who underwent coronary artery bypass graft (CABG)…
- Trial name
- VR-CABG (NCT07891299)
- Testing
- VR Shinecon G04EA Virtual Reality Headset
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Maltepe University
Pain, Acute Post-Operative, Ambulatory Surgical Procedures
Machine Learning-Based Prediction of Postoperative Pain After Pediatric Ambulatory Surgery
This study aims to predict pain after surgery in children of ages 1 to 3 years by using computer programming (machine learning). Participant children will be observed before, during, and after surgery.
- Conditions
- Pain, Acute Post-Operative, Ambulatory Surgical Procedures, Pediatric Pain, Pediatric Patient (1m-21y)
- Trial name
- NCT07274995
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Preoperative Anxiety, Virtual Reality
The Effect of Virtual Reality Education on Preoperative Anxiety, Postoperative Pain, and Sleep in Patients Undergoing Colon Surgery
The effect of patient education given to patients undergoing colon surgery using virtual reality in the preoperative period on preoperative anxiety, postoperative pain and sleep is the subject of this study.
- Conditions
- Preoperative Anxiety, Virtual Reality, Postoperative Pain Management, Postoperative Sleep
- Trial name
- NCT07297095
- Testing
- preoperative patient education via virtual reality device
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Yildirim Beyazıt University
Post Operative Pain, Regional Block
PENG and LFCN Block Versus Lumbar Plexus Block for Postoperative Analgesia After Total Hip Arthroplasty
Regional anesthesia for postoperative analgesia in THA includes epidural anesthesia and peripheral nerve blocks. However epidural anesthesia has a great role in THA, it has become restricted as perioperative antithrombotic drugs…
- Trial name
- NCT05652075
- Testing
- pericapsular nerve group and lateral femoral cutaneous nerve block, lumbar plexus block
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Minia University
Post Operative Pain
Effects of a Combination of IV-PCA With Continuous IV Infusion of MO, Versus IV-PCA MO on Postoperative Pain
After major surgery, such as abdominal or thoracic surgery, the majority of patients experience moderate to severe pain that may not be optimally controlled.
- Trial name
- NCT00849719
- Testing
- a combination of PCA MO and continuous infusion of MO, PCA MO only
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Implant, Analgesia
Low Level Laser (LED) Use to Increase Dental Implant Stability and Post Operative Analgesia
Study hypothesis: Low level laser (LED) will reduce initial bone resorption and improve primary stability of dental implant. It will also reduces post operative pain compared to patient without treatment Implant osseointegration…
- Trial name
- NCT01097499
- Testing
- OsseoPulse device (Light emitting diode technology)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Post Operative Pain Control
Effect of a Multimodal Pain Regimen on Pain Control, Patient Satisfaction and Narcotic Use in Orthopaedic Trauma Patients
The study is a prospective, randomized, open-label comparison of a multimodal regimen and a standard, narcotic-based regimen for postoperative pain control in patients undergoing surgery for an operatively indicated, isolated…
- Trial name
- NCT02160301
- Testing
- Gabapentin, Acetaminophen, Celecoxib
- Where
- United States
- Sponsor
- University of North Carolina, Chapel Hill
Umbilical Hernia
Analgesic Efficacy After Umbilical Hernia Repair in Children
Umbilical hernia repair is a common painful outpatient procedure performed in children. Often analgesia for this procedure is provided by using local infiltration of the surgical site by the surgeons and perioperative opioids and…
- Trial name
- NCT00578136
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Children's Hospital of Philadelphia
Postoperative Pain, Nephrolithotomy, Percutaneous
Effectivenes of Erector Spinae Plane Block in Percutaneous Nephrolithotomy?
This study investigates the effectiveness of the erector spinae plane block (ESPB) in pain management of patients undergoing PNL.
- Conditions
- Postoperative Pain, Nephrolithotomy, Percutaneous, Erector Spinae Plane Block
- Trial name
- NCT04474873
- Testing
- erector spinae block
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Ankara City Hospital Bilkent
Hip Surgery, Postoperative Pain Management
Comparison of Intermittent Bolus vs. Continuous Infusion PENG Block for Postoperative Pain in Hip Surgery
This retrospective study evaluates the effects of two different administration methods of the Pericapsular Nerve Group (PENG) Block on postoperative pain control, opioid consumption, and recovery in patients undergoing hip…
- Conditions
- Hip Surgery, Postoperative Pain Management, Pericapsular Nerve Group Block (PENG Block), Regional Anesthesia
- Trial name
- ICPENG (NCT06834243)
- Testing
- Intermittent Bolus PENG Block, Continuous Infusion PENG Block
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Onur Baran
Shoulder Injuries, Pain, Postoperative
Battlefield Acupuncture Following Shoulder Surgery
The purpose of this randomized clinical trial is to determine the effectiveness of Battlefield Acupuncture (BFA) in addition to standard post-surgical shoulder physical therapy compared to a standard shoulder rehabilitation…
- Conditions
- Shoulder Injuries, Pain, Postoperative, Acupuncture, Ear, Pain Management
- Trial name
- BFA (NCT04094246)
- Testing
- Battlefield Acupuncture, Standard post-surgical rehabilitation
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Keller Army Community Hospital
Anxiety, Postoperative Pain
Developing a Virtual Reality (VR)-Based Prototype for Perioperative Care - a Proof of Concept Study
Preoperative anxiety and acute post-operative pain are common and have been associated with the development of chronic post-surgical pain and longer hospitalisation.
- Conditions
- Anxiety, Postoperative Pain, Pain, Acute
- Trial name
- NCT05564013
- Testing
- Virtual reality
- Where
- 2 sites in Singapore
- Volunteers
- 160 people
- Sponsor
- Changi General Hospital