Clinical trials: Postdural Puncture Headache
Post-dural Puncture Headache, Post-dural Puncture Backache
Long-term Effects of Accidental Dural Puncture in Patients Having Had an Epidural Blood Patch (LEAP)
Accidental dural puncture (ADP) during placement of an epidural catheter for anesthesia and analgesia is a well known complication. Previous studies have found audiometric deterioration following ADP.
- Trial name
- LEAP (NCT02149680)
- Where
- 2 sites in Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Spontaneous Intracranial Hypotension, Intracranial Hypotension
Pathophysiology and Treatment of Cerebrospinal Hypotension Exploration Study
The goal of this observational study is to learn about the effects of a low-pressure environment on the brain in patients with intracranial hypotension and to potentially improve diagnostics and treatment of this condition.
- Conditions
- Spontaneous Intracranial Hypotension, Intracranial Hypotension, Post-Lumbar Puncture Headache
- Trial name
- PATCHES (NCT06805591)
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Postdural Puncture Headache
Study Evaluating Sphenopalatine Ganglion Block (SPGB) for Treatment of Postdural Puncture Headache (PDPH)
Postdural puncture headaches (PDPH) are a consequence of spinal and epidural anesthesia in approximately 1% of cases when performed in obstetric patients.
- Trial name
- PDPH (NCT02365909)
- Testing
- 0.5% bupivacaine, normal saline
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Postdural Puncture Headache
Lumbar Spine Ultrasound of Patients With Previous Accidental Dural Puncture During Labour Epidural
Accidental dural puncture is a potential complication of epidural analgesia for labour and delivery. When it happens, it may cause debilitating headaches and other symptoms that prevent mothers from talking care of their…
- Trial name
- NCT00465166
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Post-Dural Puncture Headache
Effect of Nebulized Dexmedetomidine on Post-dural Puncture Headache
Dural puncture during neuroaxial procedures is the most frequent major complication that causes the development of post-dural puncture headache (PDPH) in 16%-86% of cases.
- Trial name
- NCT06470854
- Testing
- Nebulized Dexmedetomidine, Bilateral greater occipital nerve block
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tanta University
Parturient Who Underwent Epidural Anesthesia During Which an Unintentional Dural Punctur Occurred, Parturient Who Develop a Postdural Puncture Headache
Chronic Headache and Chronic Backache Following Unintentional Dural Puncture at Delivery Room.
he study is a telephone questionnaire. The study will include 400 women, 100 in each group. OBJECTIVE: To investigate the prevalence of chronic and chronic back pain following PDPH accidental dural puncture during epidyral…
- Conditions
- Parturient Who Underwent Epidural Anesthesia During Which an Unintentional Dural Punctur Occurred, Parturient Who Develop a Postdural Puncture Headache, Parturient Who Gave Informed Consent to Participation in the Study
- Trial name
- NCT03908424
- Testing
- Epidural Blood patch.
- Where
- Israel
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Post Dural Puncture Headache
Bedside Sedation for the Prevention of Post Dural Puncture Headache
Dural or lumbar puncture (LP), the passing of a needle into the space of the spinal cord, is a common procedure in everyday clinical practice.
- Trial name
- NCT01503788
- Testing
- Midazolam
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Post-Dural Puncture Headache
Effect of Small Versus Large Epidural Needles on Postdural Puncture Headache Study
The purpose of this study is to determine the effect of 19g versus =>18g traditional Tuohy-type epidural needles on the incidence and severity of postdural puncture headache (PDPH).
- Trial name
- NCT00370604
- Testing
- 19g Tuohy-type epidural needle, 23g catheter, => 18g Tuohy-type needle
- Where
- 4 sites in Canada
- Volunteers
- 1,081 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Post-Dural Puncture Headache
Bilateral Sphenopalatine Ganglion Block With or Without Bilateral Greater Occipital Nerve Block for Treatment of Obstetric Post-Dural Puncture Headache
Post-dural puncture headache is a common complication, following neuraxial techniques. The obstetric population is particularly prone to PDPH. Therefore, treatment of PDPH is a key issue in obstetric anesthesia.
- Trial name
- NCT04844229
- Testing
- Bilateral transnasal sphenopalatine ganglion block., Bilateral ultrasound guided greater occipital nerve block.
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Anesthesia
Postdural Puncture Headache Relief With Aminophylline and SPGB
The purpose of the study is to compare Sphenopalatine ganglion block (SPGB) and aminophylline in the efficacy and safety management of PDPH.
- Trial name
- NCT05552404
- Testing
- conservative therapy, Aminophylline, trans nasal sphenopalatine ganglion block
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postdural Puncture Headache, Post-Lumbar Puncture Headache
Incidence of Headache Following an Unintentional Dural Puncture
The purpose of this study is to evaluate the use of intrathecal morphine administration following an unintentional dural puncture, to decrease the incidence of post dural puncture headaches (PDPH) in obstetric patients.
- Conditions
- Postdural Puncture Headache, Post-Lumbar Puncture Headache, Cerebrospinal Fluid Leaks
- Trial name
- NCT01977898
- Testing
- Morphine, Saline
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Postdural Puncture Headache
Therapeutic Epidural Patch Versus Pain Block in the Midface for Headache
The purpose of this study is to compare a pain block in the midface, versus the traditional, more invasive, therapeutic epidural patch for the treatment of headaches
- Trial name
- NCT03112720
- Testing
- Epidural Blood Patch, Sphenopalatine Ganglion Block
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Postdural Puncture Headache
Prediction of Post-dural Puncture Headache in Parturients Undergoing Elective Caesarean Section
The parturients are at particular risk of post dural puncture headache (PDPH) because of their sex, young age, and the widespread application of spinal and epidural anesthesia.
- Trial name
- NCT03464253
- Testing
- Performance of the transcranial Doppler (TCD)
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Hypotension After Spinal Anesthesia, Post-Dural Puncture Headache
Effects of Preoperative Coffee Consumption in Cesarean Sections Under Spinal Anesthesia
The prospective study is planned in a university hospital. Spinal anesthesia is widely used for cesarean section currently for its safety, low cost, reliability, easiness to administer, immediate effect, and well-operating…
- Trial name
- NCT05262933
- Testing
- coffee, Water
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Postdural Puncture Headache
Addition of Pyridostigmine to Conventional Management of Postdural Puncture Headache
Postdural puncture headache (PDPH) is a major complication of neuraxial anesthesia that can occur following spinal anesthesia and with inadvertent Dural puncture during epidural anesthesia.
- Trial name
- NCT05969119
- Testing
- Pyridostigmine
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Post-Dural Puncture Headache, Chronic Headache
Long-term Complications of Unintentional Dural Puncture During Labour Epidurals and Epidural Blood Patch.
The investigators plan to evaluate long-term consequences of unintentional dural puncture in women who had this complication during labor epidural insertion at Mount Sinai Hospital.
- Trial name
- NCT04696627
- Testing
- Questionnaire
- Where
- Canada
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Analgesia
Management of Post Dural Pucture Headache After Lower Limb Surgeries: Oral Prednisolone vs Oral Pregabalin
The aim of this study is to compare between oral prednisolone and oral pregabalin in management of PDPH to detect effectiveness of the treatment in reducing severity of PDPH, total rescue analgesic consumption and adverse effects…
- Trial name
- NCT04662125
- Testing
- caffeine, paracetamol tablet, Oral prednisolone, oral pregabalin
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Post-Dural Puncture Headache
Evaluation of Post-dural Puncture Headache in Female Patients Undergoing Obstetric and Non-obstetric Surgery
The goal of this observational study is to compare the incidence, severity, and potential risk factors for Post-dural Puncture headaches (PDPH) in obstetric and non-obstetric female patients undergoing spinal anesthesia.
- Trial name
- NCT06992063
- Testing
- Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Duzce University
Postdural Puncture Headache
2 Dose Neuraxial Morphine for Prevention of PDPH
Neuraxial analgesia (most commonly continuous epidural or combined spinal epidural) is the most effective modality available for pain relief during labor.
- Trial name
- NCT02473276
- Testing
- Morphine, Sterile normal saline
- Where
- 4 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Columbia University
Post-Dural Puncture Headache
The Sphenopalatine Ganglion Block for Post-dural Puncture Headache
This study aims to determine the efficacy of the sphenopalatine ganglion block in the treatment of post-dural puncture headache in post-partum women at the Brigham and Women's Hospital by measuring VAS scores at times between 0…
- Trial name
- NCT03385772
- Testing
- Sphenopalatine ganglion block
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital