Clinical trials: Postoperative Muscle Loss
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Sepsis, Primary Myopathies
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies
The primary aim of the project is to apply the non-invasive stimulated muscle force assessment system to i) intensive care unit patients and ii) patients with primary myopathy or subclinic myopathy (e.g., Duchenne muscular…
- Trial name
- NCT00735384
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Trauma, Nutritional Deficiency
Trauma Screening and Supplementation
The purpose of the proposed study is twofold: 1) The investigators will evaluate ultrasound imaging to screen trauma patients to identify patients at increased risk of postoperative complications associated with sarcopenia.
- Conditions
- Trauma, Nutritional Deficiency, Wound Heal
- Trial name
- NCT03658278
- Testing
- Juven
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Michael C Willey
Sarcopenia, Sarcopenic Obesity
Effects of Sarcopenia and Sarcopenic Obesity in Complex Abdominal Wall Surgery
The objective of our study is to evaluate the prevalence of sarcopenia and sarcopenic obesity in our surgical population and their relationship in postoperative complications after complex abdominal wall surgery and its influence…
- Conditions
- Sarcopenia, Sarcopenic Obesity, Incisional Hernia
- Trial name
- NCT04690179
- Volunteers
- 150 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Gynecologic Cancer, Frailty
Measuring Ultrasound Guided Skeletal Muscle Mass of Lower Extremity as a Predictor of Post-Operative Length of Stay in Exploratory Gynae-oncology Surgeries
Increased incidence of Gynae-oncological cancer is observed specifically in women above 50 years of age. Sarcopenia (a progressive and generalized loss of skeletal muscle mass, quality, and strength) is considered a reliable…
- Conditions
- Gynecologic Cancer, Frailty, Sarcopenia
- Trial name
- MUSLES (NCT06816836)
- Testing
- Bed Side ultrasound guided muscle mass estimation of lower extremity
- Where
- India
- Volunteers
- 320 people
- Sponsor
- Tata Medical Center
Cancer, Postoperative Complications
Association Between Different Parameters of Nutritional Assessment and Clinical Outcomes in Cancer Patients
Malnutrition in oncologic patients has a negative impact on post- surgical recovery, survival and quality of life. The etiology of malnutrition in cancer patients is multifactorial, therefore, the nutritional assessment should be…
- Conditions
- Cancer, Postoperative Complications, Sarcopenia
- Trial name
- NCT02901132
- Where
- 2 sites in Brazil
- Volunteers
- 120 people
- Sponsor
- Federal University of Minas Gerais
Perioeprative Muscle Loss
BCAA in Patients Undergoing Gastric Cancer Surgery
Older patients undergoing gastric cancer resection, at higher risk due to insufficient preoperative muscle mass, are more susceptible to SRML under surgical stress.
- Trial name
- NCT06340399
- Testing
- BCAA, patient not administered BCAA
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Hip Fracture, Malnutrition
GNRI and Rectus Femoris Muscle Thickness in Older Patients Undergoing Hip Fracture Surgery
This prospective observational study will evaluate whether nutritional risk and reduced muscle mass are associated with postoperative outcomes in adults aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Hip Fracture, Malnutrition, Sarcopenia, Postoperative Complications
- Trial name
- NCT07751692
- Testing
- Geriatric Nutritional Risk Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Colorectal Cancer, Colorectal Neoplasms
Resistance vs Aerobic Prehabilitation Before Colorectal Cancer Surgery
The goal of this clinical trial is to learn which type of exercise before surgery best reduces complications after colorectal surgery in adults with colorectal cancer or precancerous lesions.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Postoperative Complications
- Trial name
- NCT07896174
- Testing
- Resistance Training Prehabilitation, Aerobic Training Prehabilitation, Standard Trimodal Care
- Where
- Hungary
- Volunteers
- 480 people
- Sponsor
- Semmelweis University
Sarcopenia, Colonic Neoplasms
ERAS in Colorectal Surgery Diminishes the Negative Impact of Sarcopenia on Short Term Outcomes
So far, the impact of sarcopenia has been analysed only in patients undergoing traditional surgical procedures (laparotomy) or those with metastatic spread.
- Trial name
- NCT02618811
- Where
- Poland
- Volunteers
- 171 people
- Sponsor
- Jagiellonian University
Sarcopenia, Postoperative Complications
Sarcopenia in Colorectal Cancer Patients, Intervention Study
The sarcopenia is a new concept for evaluating the functional status of patients, introduced during the last 20 years. This is defined as the relationship between the deterioration of muscle mass and the decrease in strength, the…
- Conditions
- Sarcopenia, Postoperative Complications, Infection;Post Surg Procedure
- Trial name
- NCT05491434
- Testing
- Protein supplement
- Where
- Spain
- Volunteers
- 370 people
- Sponsor
- Hospital Universitari de Bellvitge
Sarcopenia, Hepatobiliary Disease
Evaluation of the Sarcopenia in Hepatobiliary Surgery
The sarcopenia is defined as a loss of muscle mass and a loss of muscle function ( strength or performance). Some studies showed that the sarcopenia increase the postoperative complications and the overall survival in abdominal…
- Conditions
- Sarcopenia, Hepatobiliary Disease, Postoperative Complications, Surgery
- Trial name
- SARFO (NCT03754452)
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Angers
Sarcopenia, Bladder Cancer
SArcopenia, Mobility, PHYsical Activity and Post-operative Risk of Bladder Carcinoma in the Elderly
Sarcopenia is associated with lower prognosis in solid tumors, but this has not been studied in bladder carcinoma requiring cystectomy.
- Trial name
- SAMPHYR (NCT03362801)
- Testing
- sarcopenia and mobility measurement
- Where
- 3 sites in France
- Volunteers
- 69 people
- Sponsor
- University Hospital, Caen
ACL Reconstruction, ACL Surgery
Post Operative Use of Neuromuscular Electrical Stimulation (NMES) Device for ACLR Patients
This study is being conducted to learn about how neuromuscular electrical stimulation (NMES) in addition to standard of care aids in the recovery of muscle strength in patients undergoing ACLR procedure.
- Conditions
- ACL Reconstruction, ACL Surgery, ACL Injury, Electrotherapy
- Trial name
- NCT07171346
- Testing
- Zynex NexWave Electrotherapy Device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Kansas Medical Center
Postoperative Muscle Loss
Postoperative Muscle Loss After Gastrectomy
Investigating postoperative muscle loss after gastrectomy
- Trial name
- NCT07331038
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Anterior Cruciate Ligament Reconstruction, Volumetric Muscle Loss
Blood Flow Restriction Training in Rehabilitation Patients
Occlusion training, resistance exercise performed with a specialized venous tourniquet, leads to beneficial changes in muscle at low resistance and minimal stress on the nearby joint.
- Conditions
- Anterior Cruciate Ligament Reconstruction, Volumetric Muscle Loss, Chronic Thigh Muscle Weakness, Knee Arthroscopy
- Trial name
- NCT02174770
- Testing
- Blood Flow Restriction (BFR) Training, Standard ACSM-guided strength training
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Brooke Army Medical Center
Frailty, Sarcopenia
Frailty and Muscle Strength Tests in Older Adults Undergoing Major Surgery
The goal of this observational study is to learn if simple tests for frailty and muscle strength can help predict which older adults (age 65 and older) are at higher risk for problems after major abdominal surgery.
- Conditions
- Frailty, Sarcopenia, Sarcopenia in Elderly, Muscle Strength
- Trial name
- NCT06988176
- Testing
- Frailty assessment, nutrition assessment, cognition assessment, muscle strength testing
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Pain, Shoulder, Postoperative Pain
The Effects of Qigong Exercise Training After Thoracotomy
Postoperative pulmonary complications after thoracotomy cause morbidity and mortality. Although the causes of postoperative pulmonary complication are multifactorial, respiratory muscle dysfunction is a contributing factor to the…
- Conditions
- Pain, Shoulder, Postoperative Pain, Joint Adhesion, Muscle Weakness
- Trial name
- NCT05470192
- Testing
- Qigong exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Akdeniz University
Muscle Atrophy, Surgery
Use of Testosterone to Prevent Post-Surgical Muscle Loss - Pilot Study
The loss of muscle mass post-surgery confounds recovery efforts and leads to a delay in patient's ability to return to activities.
- Conditions
- Muscle Atrophy, Surgery, Knee Injuries and Disorders, Complication of Surgical Procedure
- Trial name
- NCT04456530
- Testing
- Aveed 750 MG in 3 ML IM Injection, Normal Saline 3 ML IM Injection
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The Stone Research Foundation for Sports Medicine and Arthritis
Hip Fractures, Muscle Atrophy
The Role of Blood Flow Restriction Therapy in Postoperative Elderly Patients With Hip Fracture
The investigators aim to study the use of blood flow restriction therapy (BFR) to augment routine post-operative physical therapy in elderly patients (age >= 65) after recovering from surgical treatment of hip fractures.
- Trial name
- NCT04809714
- Testing
- Blood Flow Restriction with Delfi Tourniquet System Cuff, Routine Post-operative Physical Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham