Clinical trials: Postoperative Pain, completed
Sports Physical Therapy
Comparative Effects of Neuromuscular Training Vs Close Chain Exercises in Athletes With Post Operative ACL Injury
The aim of this study is to determine the effects of close chain exercises and neuromuscular training on pain, range of motion, strength and endurance in athletes with post operative ACL injury The study will be randomized…
- Trial name
- NMTvsCC-ACL (NCT06797102)
- Testing
- Neuromuscular Exercises, Close Chain Exercises
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
External Oblique Intercostal Fascial Plane Block, Rectus Sheath Block
External Oblique Intercostal Fascial Plane Block Versus Rectus Sheath Block for Postoperative Analgesia
This study aimed to compare the analgesic efficacy of the external oblique intercostal fascial plane block (EOIPB) versus the rectus sheath block (RSB) for managing postoperative pain following paraumbilical hernioplasty.
- Conditions
- External Oblique Intercostal Fascial Plane Block, Rectus Sheath Block, Pain
- Trial name
- NCT07601945
- Testing
- External Oblique Intercostal Fascial Plane Block for Postoperative Analgesia
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Helwan University
Postoperative Pain, Surgery
Oblique Subcostal Transversus Abdominis Plane Block Versus Transmuscular Quadratus Lumborum Block for Pain Management in Laparoscopic Gynecological Surgery
Laparoscopic gynecological surgery causes postoperative pain.The primary objective of this study is to compare the effect of ultrasound (US)-guided oblique subcostal transversus abdominis plane block (OSTAP) on 24-hour total…
- Trial name
- NCT06017401
- Testing
- Oblique Subcostal Transversus Abdominis Plane Block, Transmuscular Quadratus Lumborum Block
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Uludag University
Pain, Postoperative, Pain Prediction
Venous Cannulation Pain to Guide Choice of Anesthetic Method
The investigators have recently shown that pain associated with peripheral venous cannulation can be used to predict the risk of postoperative pain, where patients grading their pain associated with venous cannulation (VCP) above…
- Conditions
- Pain, Postoperative, Pain Prediction, Laparoscopic Surgery, Venous Cannulation Pain
- Trial name
- NCT04751812
- Testing
- High-pain multimodal anesthesia with opioids, Low-pain opioid free, Standard of care
- Where
- Sweden
- Volunteers
- 270 people
- Sponsor
- Region Halland
Post Operative Pain
Ultrasound vs. Surgical ESP Block With Bupivacaine-Dexmedetomidine in Lumbar Fusion Surgery
Lumbar spine surgery causes intense post-op pain, peaking within 12 hours and improving by day three. Traditional spinal procedures involve extensive tissue dissection, leading to severe pain and potential complications like…
- Trial name
- NCT06958718
- Testing
- Ultrasound Guided erector spinae plane block (UB), Surgical erector spinae plane block (SB), Dexmedetomidine
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Fayoum University Hospital
Post Operative Analgesia, Bariatric Surgery
Oral Acetaminophen for Post-Op Pain Management in Bariatric Surgery Patients
Adult patients with morbid obesity who have had Roux-en-Y gastric bypass (RYGB) or laparoscopic sleeve gastrectomy (LSG) surgery have impaired drug metabolism.
- Conditions
- Post Operative Analgesia, Bariatric Surgery, Bariatric Surgery (Gastric Bypass), Bariatric Surgery Patients
- Trial name
- NCT06658574
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Rutgers, The State University of New Jersey
Procedure, Gynecologic Surgical
Anesthesia on Postoperative Pain After Loop Electrosurgical Excision Procedure
The loop electrosurgical excision procedure (LEEP) is a modified cervical conization that is performed with an electrosurgical loop.
- Trial name
- NCT04984122
- Testing
- LEEP
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Post-operative Pain for Total Knee Arthroplasty
Dexmedetomidine for Sedation in Total Knee Replacements
Dexmedetomidine has demonstrated benefits both in sedation, and post-operative pain control, with less respiratory depression than other common sedatives.
- Trial name
- NCT02466022
- Testing
- Dexmedetomidine, Bupivicaine, Normal Saline
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- University of Saskatchewan
Scoliosis, Spondylolisthesis
Effect of Pregabalin on Immediate Post-operative and Longterm Pain
This study aims to evaluate the incidence of longterm pain after spinal fusion surgery in children and adolescents. In the second part of the study a randomized double-blind clinical trial will be conducted.
- Trial name
- NCT02464813
- Testing
- Pregabalin, Sugar pill, Oxycodone
- Where
- Finland
- Volunteers
- 64 people
- Sponsor
- Turku University Hospital
Prostate Cancer, Anesthesia, Local
Open Radical Prostatectomy and Erector Spinae Plane Block
In the proposed study, a bilateral erector spinae plane (ESP) block [10 ml 1%lidocaine + 10 ml 0.5 % bupivacaine vs normal saline (NS)] will be performed preoperatively to patients undergoing open radical prostatectomy.
- Conditions
- Prostate Cancer, Anesthesia, Local, Pain, Postoperative
- Trial name
- NCT04337060
- Testing
- Single-injection ultrasound-guided bilateral erector spinae plane block-Lidocaine/Bupivacaine, Pain follow-up and monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- BURHAN DOST
Postoperative Nausea and Vomiting, Postoperative Pain
Spinal Morphine and Atropine Added to General Anaesthesia for Nausea and Pain After Abdominal Laparoscopy
Laparoscopic abdominal surgery carries one of the highest risks of postoperative nausea and vomiting (PONV), and postoperative opioids given for pain are themselves emetogenic.
- Conditions
- Postoperative Nausea and Vomiting, Postoperative Pain, Anesthesia, Anesthesia Spinal
- Trial name
- NCT07851870
- Testing
- Intrathecal bupivacaine, morphine and atropine, General anaesthesia, Multimodal analgesia and antiemetic prophylaxis
- Where
- Indonesia
- Volunteers
- 63 people
- Sponsor
- Universitas Indonesia
Postoperative Pain
TQL-block for Laparoscopic Hemicolectomy
Every year 350 patients undergo surgery due to colorectal cancer at Zealand University Hospital, Roskilde. The majority of the surgeries are performed using a minimal invasive laparoscopic technique where the bowl anastomosis is…
- Trial name
- NCT03570541
- Testing
- Ropivacaine, Acetaminophen, Patient controlled analgesia
- Where
- Denmark
- Volunteers
- 69 people
- Sponsor
- Zealand University Hospital
Pain Management in Adult Females in Child Bearing Period Aging From 20 to 45 Years Who Are Scheduled for Elective Cesarean Section
Intrathecal Dexmedetomidine Versus Transversus Abdominus Plane Block (TAP) for Postoperative Analgesia After Cesarean Section.
Spinal anesthesia is the most commonly used technique for lower abdominal surgeries as it is very economical and easy to administer.
- Trial name
- NCT04969705
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Amputation, Chronic Pain
Efficacy of Opioids and Mexiletine for the Treatment of Postamputation Pain
Persistent pain occurs in 50-85 percent of patients who experience the amputation of an extremity. This study will compare the effectiveness of morphine and mexiletine to placebo in the treatment of postamputation pain.
- Trial name
- NCT00383682
- Testing
- morphine and mexiletine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Migration of Implant, Pain
Does the Mesh Have to be Fixed in Laparoscopic eTEP Repair of Inguinal Hernia?
Inguinal hernia surgery is one of the most frequently performed procedures among general surgery cases. As with many open surgical methods, this repair is also performed laparoscopically.
- Conditions
- Migration of Implant, Pain, Postoperative Complications, Relapse
- Trial name
- NCT06070142
- Testing
- TEP Group, eTEP Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mehmet Eşref Ulutaş
Coronary Artery Disease, Sternal Pain
Pecto-Intercostal Fascial Block for Postoperative Analgesia After Cardiac Surgery
The purpose of this study is to determine whether administration of a pecto-intercostal fascial plane block (PIFB) with bupivacaine is a more effective therapy for postoperative analgesia after cardiac surgery as compared to…
- Trial name
- NCT03482973
- Testing
- Bupivacaine Group
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Beth Israel Deaconess Medical Center
Total Knee Arthroplasty
The Efficacy of Adductor-Canal-Blockade on Morphine Consumption, Pain and Mobilisation After Total Knee Arthroplasty
The purpose of this study is to determine whether Adductor-Canal-Blockade is effective at reducing morphine consumption and pain, and at the same time improving mobilisation after total knee arthroplasty.
- Trial name
- NCT01104883
- Testing
- Adductor-Canal-Blockade, Adductor-Canal-blockade with saline
- Where
- 2 sites in Denmark
- Volunteers
- 70 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pain, Postoperative, Arthropathy of Knee Joint
Local Infiltration With Bupivacaine to Increase Quality of Post-operative Pain Control in Total Knee Replacement
The purpose of this study is to evaluate the efficacy of periarticular injection with 0.25% bupivacaine for controlling pain after total knee replacement to improve the quality of post-operative care.
- Trial name
- NCT01364194
- Testing
- 0.25% Bupivacaine, 0.9% normal saline
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Mammoplasty, Postoperative Pain
Study of EXPAREL in Patients Undergoing Breast Augmentation
This is a Phase 4, prospective, open-label, non-randomized, sequential study with two treatment groups differing only in the technique used for EXPAREL administration (instillation or infiltration).
- Trial name
- NCT01582490
- Testing
- Instillation - EXPAREL, Infiltration - EXPAREL
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Postoperative Pain
Efficacy of S(+)-Ketamine Administered as a Continuous Infusion for the Control of Postoperative Pain
Background: The use of low-dose continuous infusion of S(+)-ketamine combined with target-controlled intravenous anesthesia with remifentanil and propofol may be related to the control of postoperative pain and of opioid-induced…
- Trial name
- NCT02421913
- Testing
- S(+)-Ketamine
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Centro Medico Campinas
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