Clinical trials: Postprandial Period
Gastro Esophageal Reflux
Effect of Citalopram on Reflux Episodes in Healthy Volunteers
Citalopram is sometimes used in the treatment for gastro-esophageal reflux disease, however, there are no empirical data to support this.
- Trial name
- NCT03746691
- Testing
- Citalopram HCl
- Where
- Belgium
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Type 1 Diabetes
Evaluation of Fats on Postprandial Glucose Control
The purpose of this study is examine the effect of different fat types on postprandial glucose control in patients with type 1 diabetes.
- Trial name
- Nabucco (NCT01869790)
- Testing
- Different fat types
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Joslin Diabetes Center
Healthy
Metabolomic Response to Meal Ingestion
The investigators have recently shown that postprandial sensations correlate with changes in circulating metabolites after a meal ingestion; however this phenomenon was demonstrated with a meal load up to the level of tolerance…
- Trial name
- NCT03383250
- Testing
- Normal meal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Healthy
Study of the Impact of Cheese Matrix on Postprandial Lipemia: a Clinical Study
Dairy products consumption is widely recommended in a healthy diet not only for bone growth and maintenance, but also as a protein, calcium and magnesium sources for an adequate diet.
- Trial name
- FROMAGE (NCT02623790)
- Testing
- Test meal (butter), Test meal (cheddar cheese), Test meal (cream cheese)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Laval University
Dietary Fats, Carbohydrates
Macronutrients and Postprandial Vascular Function
Vascular function decreases following the intake of a mixed meal in some, but not all studies. Differences in the relative amounts of dietary fat, carbohydrates and protein present in the mixed-meal challenges may have…
- Conditions
- Dietary Fats, Carbohydrates, Proteins, Macronutrients
- Trial name
- NCT03139890
- Testing
- High-fat (HF-LC-LP) milkshake, High-carbohydrate (LF-HC-LP) milkshake, High-protein (LF-LC-HP) milkshake
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Glycemic Index
The Effect of Content of Barley Beta-glucans in Bread on Postprandial Blood Sugar
The effect of content of barley beta-glucans in bread on postprandial blood sugar will be measured with open-label crossover study.
- Trial name
- ARRS-bGL-01 (NCT03878576)
- Testing
- REFERENCE: white bread - BGL0 [RP], TEST: b-glucan enriched bread - BGL2 [IP1], TEST: b-glucan enriched bread - BGL3 [IP2]
- Where
- Slovenia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Type 2 Diabetes
Acute Studies on the Glycemic Index After Intake of Different Sorts of Barley in Subjects With Type 2 Diabetes
In a series of double-blinded randomized cross-over acute studies, the investigators want to study the effects of different types of barley on the glycemic index (GI) in subjects with type 2 diabetes.
- Trial name
- NCT04646746
- Testing
- 100% wheat, 50% nude barley and 50% wheat, 75% nude barley and 25% wheat
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Type 2 Diabetes Mellitus
Effects of Lixisenatide Compared to Liraglutide on the Postprandial Plasma Glucose in Patients With Type 2 Diabetes
The purpose of the study is to compare the pharmacodynamic effects of lixisenatide (AVE0010), in comparison to liraglutide, as an add-on treatment to metformin, over a period of 4 weeks of treatment.
- Trial name
- NCT01175473
- Testing
- Lixisenatide (AVE0010), Pen auto-injector, Liraglutide
- Where
- 7 sites in Germany
- Volunteers
- 148 people
- Sponsor
- Sanofi
Type 1 Diabetes Mellitus
Postprandial Blood Glucose Control With BioChaperone® Combo and Insulin Lispro (Humalog®) Mix 25 in People With Type 1 Diabetes Mellitus
Each subject will be randomly allocated to a sequence of two treatments applied at two separate dosing visits. At each dosing visit subjects will be injected with individualised doses of either BioChaperone® Combo or Humalog® Mix…
- Trial name
- NCT02514954
- Testing
- Biochaperone® Combo, Humalog® Mix25
- Where
- Germany
- Volunteers
- 28 people
- Sponsor
- Adocia
Type1 Diabetes
Effect of Dual-wave Insulin Bolus on Postprandial Glycaemia
A study was conducted in adolescents with type 1 diabetes (T1D) examining the effect of different bolus types on 6-h postprandial glucose levels after the consumption of 3 standard meals with varying composition.
- Trial name
- NCT03179280
- Testing
- insulin
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Biological Availability of Vitamins and Micronutrients
Effect of Genetic Variants on Fat-soluble Vitamin Bioavailability
The aim was to identify minor genetic variations (single nucleotide polymorphisms) that explain the interindividual variability in bioavailability of fat soluble micronutrients (fat soluble vitamins and carotenoids).
- Trial name
- VITAGENES (NCT02100774)
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Familial Dysbetalipoproteinemia, Hyperlipoproteinemia Type III
Effects of Evolocumab Versus Placebo Added to Standard Lipid-lowering Therapy on Fasting and Post Fat Load Lipids in Patients With Familial Dysbetalipoproteinemia
Patients with familial dysbetalipoproteinemia (FD) have increased triglycerides, non-high-density lipoprotein cholesterol (non-HDL-C), beta VLDL, premature atherosclerosis and cardiovascular disease.
- Trial name
- EVOLVE-FD (NCT03811223)
- Testing
- Evolocumab Auto-Injector [Repatha]
- Volunteers
- 30 people
- Sponsor
- UMC Utrecht
Blood Glucose, Insulin Sensitivity
A Randomized, Crossover Study to Assess the Effects of Dietary Fiber-containing Bars on Glucose and Insulin Responses
This randomized, crossover study will include four clinic visits: one screening (day -7) and three test visits (days 0, 2, 4). The objective of this study is to assess the effects of dietary fiber-containing bars, at two doses of…
- Conditions
- Blood Glucose, Insulin Sensitivity, Dietary Fiber
- Trial name
- NCT03796286
- Testing
- Medium-fiber bar, High-fiber bar, Control bar (0 g fiber)
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Type 2 Diabetes
Effect of Aqueous Cinnamon Extract on the Postprandial Glycaemia Levels in Type 2 Diabetes Mellitus
The type 2 diabetes mellitus is a chronic disease and it is a highly prevalent globally. Cinnamon is a spicy used on the traditional cuisine, which have as been associated with beneficial effects on postprandial blood glucose…
- Trial name
- NCT05145673
- Testing
- Cinnamon (OGTT plus aqueous cinnamon extract)
- Volunteers
- 36 people
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Type 2 Diabetes Mellitus
The Study of Exenatide Action on Vessel Function in Type 2 Diabetes and Prediabetes
The purpose of this investigation is to evaluate whether exenatide, a type 2 diabetes medication, will improve the function of the innermost part of the arterial wall called the endothelium after a fat-enriched meal and to…
- Trial name
- NCT01181986
- Testing
- Exenatide SC, Exenatide IV, Exendin-9
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Carl T. Hayden VA Medical Center
Alcohols, Cardiovascular Diseases
Postprandial Effect of Chinese Tea Flavor Liquor on Selected CVD Risk Factors
Background: human studies of Chinese liquor are sparse. we hypothesis that Chinese Tea Flavor liquor may be beneficial to CVD risk factors postprandially.
- Trial name
- TFL (NCT01264666)
- Testing
- Chinese tea flavor liquor, Chinese Meijiao liquor, Water control
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Neoplasms
ABSK021 Food Effect Study in Healthy Subjects
This is a randomized, open-label, two-sequence, two-cycle, cross-over study to evaluate the relative bioavailability of ABSK021 after single-dose fasting and high-fat postprandial administration in healthy subjects
- Trial name
- NCT05280483
- Testing
- ABSK021 with fed state, ABSK021 with fasted state
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Abbisko Therapeutics Co, Ltd
Postprandial Blood Glucose, Gut Microbiota
Effect of Fat Quality on Glycemic Regulation and Gut Microbiota After a Short-time Intervention in Healthy Individuals
The overall aim is to investigate effects of saturated versus polyunsaturated fat on glycemic regulation and satiety in a postprandial study with healthy individuals.
- Conditions
- Postprandial Blood Glucose, Gut Microbiota, Satiety
- Trial name
- NCT03658681
- Testing
- Saturated fat 14.9 E%, Polyunsaturated fat 13.6 E%
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Type 2 Diabetes, Postprandial Oxidative Stress
Postprandial Insulin Secretion, Oxidative Stress and Gastrointestinal Peptides in Patients With Type 2 Diabetes Versus Healthy Subjects
Insulin secretion, plasma lipids, oxidative stress markers and gastrointestinal peptides will be measured in patients with type 2 diabetes versus healthy subjects in a fasting status and in response to standard meals (at times…
- Trial name
- NCT01572402
- Testing
- Bagueutte Cheese Gourmet (Crocodille), Cous-cous sandwich, McCountry sandwich (McDonald's)
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical and Experimental Medicine
Digestive System Disease, Inflammatory Bowel Diseases
Optoacoustic Characterization of Postprandial Intestinal Blood Flow
Inflammatory activities in the gastrointestinal tract are accompanied by an increase in blood flow in the intestinal wall layers of the respective organs.
- Trial name
- NEPOMUC (NCT05160077)
- Testing
- Multispectral optoacoustic tomography (MSOT)
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
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