Clinical trials: Practices
Benign Gallbladder Disease
Single-Incision Laparoscopic Cholecystectomy with Inflexible Laparoscopic Instruments and Laparoscopy: a Single-Center Experience
Since being introduced by Mühe in 1985, laparoscopic cholecystectomy (LC) has garnered global acceptance and defined as gold standard treatment for benign gallbladder diseases (BGDs).
- Trial name
- NCT06708390
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Symptomatic Non-ruptured Abdominal Aortic Aneurysms
Investigating Practice Patterns in Symptomatic Non-ruptured Abdominal Aortic Aneurysms (AAA) in Europe
Symptomatic non-ruptured abdominal aortic aneurysms (snrAAA) remain a clinical challenge due to limited evidence and heterogeneous definitions and management strategies.
- Trial name
- DETHINE (NCT07184723)
- Where
- Austria
- Volunteers
- 130 people
- Sponsor
- Wilhelminenspital Vienna
Leber's Hereditary Optic Neuropathy (LHON)
Post Authorisation Safety Study With Raxone in LHON Patients
This study is a multicentre, prospective, non-interventional post-authorisation safety study (PASS) of the clinical outcomes for patients with LHON treated with Raxone®. No medication will be provided as part of this study.
- Trial name
- PAROS (NCT02771379)
- Testing
- Idebenone
- Where
- 26 sites in Austria, France and 4 more
- Volunteers
- 229 people
- Sponsor
- Santhera Pharmaceuticals
Asthma
Symbicort SMART (Symbicort Maintenance And Reliever Therapy)
The purpose of this study is to investigate the extent of Symbicort use in patients prescribed Symbicort as maintenance and reliever therapy.
- Trial name
- SMART (NCT00523679)
- Where
- 3 sites in South Korea
- Volunteers
- 2,000 people
- Sponsor
- AstraZeneca
Opioid Use, Unspecified, Prescription Drug Abuse (Not Dependent)
An Opioid Prescribing Nudge
Analyze baseline concurrent opioid prescribing metrics at the individual prescriber level in the Duke Health System on the identified three main outcome measures.
- Conditions
- Opioid Use, Unspecified, Prescription Drug Abuse (Not Dependent), Prescription Drug Abuse and Dependency, Health Behavior
- Trial name
- OHS (NCT04069403)
- Testing
- Automated Reports on prescription patterns for their patients
- Where
- United States
- Volunteers
- 427 people, healthy volunteers welcome
- Sponsor
- Duke University
Identification (Psychology)
An Online 5-week Professional Identity Group Psychotherapy
This is an online 5-week group psychological intervention for the nursing students during clinical rotation practice. It aims at promoting the professional identity and career sefl-efficacy for them.
- Trial name
- NCT04416074
- Testing
- An online 5-week professional identity group psychotherapy, Message push
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Central South University
Heart Failure, Heart Failure With Reduced Ejection Fraction
Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations - Heart Failure (BETTER CARE-HF)
Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations - Heart Failure (BETTER CARE-HF) is a pragmatic, cluster-randomized, three-arm intervention trial that will compare the effectiveness of two…
- Trial name
- BETTER CARE-HF (NCT05275920)
- Testing
- Best Practice Alert (BPA), In-Basket Message
- Where
- United States
- Volunteers
- 2,211 people
- Sponsor
- NYU Langone Health
Astigmatism
Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day
The purpose of this study to assess the wear experience of people who have astigmatism when wearing a daily disposable contact lens for astigmatism over long days of wear.
- Trial name
- NCT07303920
- Testing
- Daily disposable contact lenses for astigmatism
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Obturation
The Effect of Clinical Experience on the Quality of Obturation and Periapical Changes of Teeth Treated With Matched Cones in Combination With Bioceramic Sealer
Evaluation of the impact of clinical experience on the quality of obturation and periapical changes of clinical cases using lateral compaction with bioceramic sealers and matched cone obturation with bioceramic sealers both…
- Trial name
- NCT06260423
- Testing
- Experienced dentist using lateral compaction with bioceramic sealer., Unexperienced dentist using lateral compaction with bioceramic sealer., Experienced dentist using Single cone with bioceramic sealer.
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Breast Cancer
The Immersive Experience of Virtual Reality During Chemotherapy in Patients With Early Breast and Gynecological Cancers: the Patient's Dream Study
"Patient's dream" study is a two-arm randomized controlled trial that will be conducted at Regina Elena National Cancer Institute, IRCCS (Rome), from April 2019 to January 2020.
- Trial name
- NCT05234996
- Testing
- 3 Virtual Reality headset (VR Headset),
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Coronary Artery Disease, Cardiac Disease
Prospective Multicenter Registry On RadiaTion Dose Estimates Of Cardiac CT AngIOgraphy IN Daily Practice in 2017
The "Prospective Multicenter Registry On RadiaTion Dose Estimates Of Cardiac CT AngIOgraphy IN Daily Practice in 2017" (PROTECTION-VI) study is a prospective registry and investigator-initiated initiative without third-party…
- Conditions
- Coronary Artery Disease, Cardiac Disease, Malignancy, Second
- Trial name
- PROTECTION-VI (NCT02996903)
- Where
- 4 sites in United States, Canada and 2 more
- Volunteers
- 4,502 people
- Sponsor
- LMU Klinikum
Penile Amputation
Replantation Following Complete Penile Amputation
The goal of this observational study Replantation following Complete Penile Amputation a case series before and after study is to help andrologist and urologists deal with such rare male emergencies easily in emergency situation.
- Trial name
- NCT06244927
- Testing
- Replantation surgery
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Sir Run Run Shaw Hospital
Healthy
Comparing Random Allocation and Allocation by Preference to Mindfulness Practice
The goal of this randomized controlled study is to examine whether allocation based on preference to one of two brief mindfulness meditation practices (mindfulness of the breath or mindfulness of sounds) influences the…
- Trial name
- NCT06402461
- Testing
- Mindfulness of the breath, Mindfulness of sounds, Audiobook control
- Where
- United Kingdom
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Canterbury Christ Church University
Rheumatoid Arthritis
Re³ (Re-Cube: Retain Remicade® Response)(Study P04249AM3)
This Phase IIIb, randomized, multi-national, multi-center, blinded study of Infliximab (IFX) in subjects aged 18 and older with active RA is being conducted to assess whether increasing either the infusion dose or infusion…
- Trial name
- Re³ (NCT00394589)
- Testing
- Infliximab Increased Frequency, Infliximab Increased Dose, Infliximab Control
- Volunteers
- 43 people
- Sponsor
- Merck Sharp & Dohme LLC
Rheumatoid Arthritis
A Non-Interventional Study of RAYOS in Adult Patients With Rheumatoid Arthritis
The overall objective of the study is to assess the effectiveness of switching from immediate-release prednisone (conventional) therapy to delayed-release prednisone (RAYOS) in patients with moderately to severely active…
- Trial name
- SUNRAY (NCT02287610)
- Testing
- RAYOS (delayed-release prednisone)
- Volunteers
- 75 people
- Sponsor
- Amgen
Recurrent Genital Herpes (RGH)
RELIEF: Randomized Episodic Versus Long-Term Suppression Experience With Famciclovir
This trial will assess whether RGH patients who have two recurrent episodes within a three month period would benefit from suppressive treatment and whether patients prefer episodic therapy or suppressive therapy for the…
- Trial name
- NCT00219310
- Testing
- Famciclovir
- Where
- United States
- Sponsor
- Novartis
No-Show Patients
Importing Quality Improvement Practices and Enhance Health Education to Improving Quality of Bowel Preparation
Importing quality improvement practices and enhances health education to improving quality of bowel preparation for health screening colonoscopy This is a retrospective data analysis study aimed at obtaining the types of…
- Trial name
- NCT03945890
- Where
- Taiwan
- Volunteers
- 2,104 people
- Sponsor
- Far Eastern Memorial Hospital
Schizophrenic Patients
Effects of tES Combined With Retrieval Practice on Semantic Memory in Patients With Schizophrenia
The semantic processing deficit stands as a central feature of cognitive abnormalities in schizophrenia. Both transcranial electrical stimulation (tES) and retrieval practice have been demonstrated as external techniques capable…
- Trial name
- NCT06547996
- Testing
- tES-tDCS group, tES-tACS group
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Northeast Normal University
Acute Respiratory Failure, Pneumonia
Practice of Oxygenation and Respiratory Support During Fiberoptic Bronchoscopy
The current practice of oxygenation and/or ventilation supports in patients undergoing Fiberoptic Bronchoscopy is very heterogeneous among studies published in the literature; in addition, clear outcomes advantages of one…
- Conditions
- Acute Respiratory Failure, Pneumonia, Lung Cancer, Fibrosis Lung
- Trial name
- NCT05681962
- Testing
- Bronchoscopy
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- University Magna Graecia
Cardiac Arrest (CA)
The Effect of Virtual Reality-Assisted Escape Room Experience
The aim of this study is to improve associate degree Dialysis Program students' Basic Life Support (BLS) knowledge and skills through a virtual reality (VR)-supported escape room intervention.
- Trial name
- VR (NCT07846124)
- Testing
- Virtual Reality-Supported Escape Room Training, Control Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
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