Clinical trials: Pragmatic Randomized Controlled Trial
Overweight, Obesity
Hockey Fans in Training (Hockey FIT): A Pilot Pragmatic Randomized Controlled Trial
The Hockey Fans in Training (Hockey FIT) program aims to improve overweight men's physical fitness, eating habits and health-related lifestyle choices through a lifestyle modification program in collaboration with two Ontario…
- Trial name
- NCT02396524
- Testing
- Hockey FIT Program
- Where
- 2 sites in Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Lung Cancer
Digital Outreach Intervention for Lung Cancer Screening
mPATH-Lung (mobile Patient Technology for Health - Lung) is an innovative digital outreach program that identifies patients who qualify for lung cancer screening and helps them get screened.
- Trial name
- mPATH-Lung (NCT04083859)
- Testing
- mPATH-Lung, Lung health video
- Where
- 2 sites in United States
- Volunteers
- 26,998 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Smoking, Smoking Cessation
Intervention Study for Smoking Cessation in Spanish College Students
This study evaluate the effectiveness of a nurse multi-component intervention aimed at helping Spanish college student smokers to quit smoking.
- Trial name
- NCT03448900
- Testing
- Multicomponent intervention, Brief advice
- Where
- Spain
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Preventive Effectiveness, Elderly With Qi-deficiency Constitution
The Preventive Effectiveness of the Individualized Jade Wind-Barrier Herbal Tea Bag on the Common Cold in Elderly With Qi-deficiency Constitution (CCJWBT): A Pragmatic Randomized Controlled Trial
Objectives Based on the individualized Jade Wind-Barrier Herbal Tea Bag intake after randomization, to evaluate the relationship of the individualized Jade Wind-Barrier Herbal Tea Bag intake and the improvement of Qi-deficiency…
- Conditions
- Preventive Effectiveness, Elderly With Qi-deficiency Constitution, The Individualized Jade Wind-Barrier Herbal Tea Bag, Common Cold
- Trial name
- CCJWBT (NCT05640570)
- Testing
- The individualized Jade Wind-Barrier Herbal Tea Bag
- Where
- China
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
HIV/AIDS, Sexually Transmitted Infections
A Pragmatic Trial to Expand Youth-friendly HIV Self-testing
The current study extends the study team's earlier efforts described in ClinicalTrail ID#: NCT04070287 and NCT03874663. The I-TEST (Innovative Tools to Expand Youth-friendly HIV Self-Testing) study known locally as the 4 Youth by…
- Trial name
- I-TEST (NCT04710784)
- Testing
- Sexual health information, I-TEST branded HIVST package, Follow-up testing and clinic assessments
- Where
- Nigeria
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Plasmodium Vivax Malaria, Malaria
FocaL Mass Drug Administration for Vivax Malaria Elimination
FLAME is an open-label cluster-randomized controlled trial that aims to determine the effectiveness of focal mass drug administration (fMDA) to reduce the incidence of Plasmodium vivax malaria in the Loreto Department in Peru.
- Trial name
- FLAME (NCT05690841)
- Testing
- Focal Mass Drug Administration (fMDA)
- Where
- Peru
- Volunteers
- 7,530 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Mobile Health Apps, Lifestyle Intervention
Effectiveness of an AI-Enabled Mobile Intervention on Lifestyle Behaviors and Maternal-Infant Health
The goal of this pragmatic randomized controlled trial is to evaluate the effectiveness of an AI-enabled mobile health management application ("Better Pregnancy" app), grounded in the Theory of Planned Behavior, in preventing…
- Conditions
- Mobile Health Apps, Lifestyle Intervention, Prevention, Multi-component Based Behavioral Intervention
- Trial name
- NCT07582068
- Testing
- Multi-component lifestyle intervention
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Psychological Trauma, Trauma and Stress Related Disorders
Trauma-Focused Intervention With Women Experiencing Homelessness
Homelessness and associated traumas disproportionately affect women. The biopsychosocial health consequences of untreated trauma are profound.
- Conditions
- Psychological Trauma, Trauma and Stress Related Disorders, Substance-Related Disorders, Substance Use
- Trial name
- NCT05873517
- Testing
- Immediate Narrative Exposure Therapy (NET)+, Waitlist + NET+
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Cervical Disc Herniation
Pharmacopuncture Therapy for Cervical Disc Herniation: A Pilot Study
This is pilot study for a 3-arm parallel pragmatic randomized controlled trial that will compare pharmacopuncture therapy, acupunture therapy and physical therapy, medication(prn) for cervical disc herniation.
- Trial name
- NCT05240586
- Testing
- pharmacopuncture therapy, acupuncture therapy, physical therapy, medication(prn)
- Where
- 7 sites in South Korea
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Jaseng Medical Foundation
Substance Withdrawal Syndrome
EA for PAAS: A pRCT
In 2019, around 27 million people worldwide, corresponding to 0.5% of the adult population, have used amphetamine-type stimulants (ATS). More than one-third of these 27 million users of ATS were in East and South-East Asia.
- Trial name
- NCT04917185
- Testing
- Electro-Acupuncture
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Tuberculosis (TB)
Research on Key Interventional Technologies for Controlling the Epidemic in High-prevalence Areas of Tuberculosis in Guangxi, China
The goal of this study is to find out if using mobile vans with advanced technology can help reduce tuberculosis (TB) in rural Guangxi, China. The study will also examine how practical and cost-effective this approach is.
- Trial name
- NCT06702774
- Testing
- Active case finding
- Where
- China
- Volunteers
- 43,067 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Eccentric Cycling Exercise Training
Effectiveness of Eccentric Cycling Exercise in Ambulatory Rehabilitation for Patients With Cardiopulmonary Diseases: A Pragmatic Randomized Controlled Trial
In eccentric cycling exercise (ECC), the cyclist must oppose backwards moving pedals on a specialized motor-driven ergometer. Throughout this process, the force applied on the pedals exceeds the torque generated by the…
- Trial name
- NCT07815366
- Testing
- Eccentric cycling exercise
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Preterm Birth, Pregnancy
An Electronic Medical Record Alert of Progesterone
Progesterone can be given to women at risk for preterm birth, and is advocated by many guidelines as progesterone has been shown to markedly decrease preterm birth, death in newborns, and disability.
- Trial name
- NCT03219489
- Testing
- Electronic medical record alert
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- McMaster University
Food Allergy in Infants
Early Allergen System Experience
Multiple clinical trials have demonstrated that early allergen introduction, feeding babies common food allergens before six months, decreases children's risk of developing a food allergy.
- Trial name
- EASE (NCT06262867)
- Testing
- Ready. Set. Food! Stage 1 Mix ins
- Where
- United States
- Volunteers
- 1,110 people, healthy volunteers welcome
- Sponsor
- Prollergy dba Ready Set Food
Human Papillomavirus 16, Human Papillomavirus 18
Integrated Cervical Cancer Screening in Mayuge District Uganda (ASPIRE Mayuge)
The purpose of this pragmatic cluster randomized control trial is to test the effectiveness of cervical cancer screening follow-up completion using two implementation approaches for self-collected HPV testing in a rural…
- Conditions
- Human Papillomavirus 16, Human Papillomavirus 18, Papillomavirus Infections, Cervical Cancer
- Trial name
- ASPIRE (NCT04000503)
- Testing
- Self-collected HPV testing for cervical cancer screening
- Where
- Uganda
- Volunteers
- 2,019 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Stroke, Influenza Human
Vaccination Nudges From Pharmacists
The goal of this individual-level pragmatic randomized policy trial is to learn about the impact of behavioural nudges via mailed letters on increasing influenza and travel vaccination uptake in Alberta, Canada.
- Conditions
- Stroke, Influenza Human, Influenza Vaccines, Health Behavior Change
- Trial name
- NCT07161739
- Testing
- Behavioural Nudge (Influenza Risk Reduction), Behavioural Nudge (Travel Vaccination Benefit)
- Where
- Canada
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Intracranial Hemorrhages, Surgery
Evaluation of Surgery in Elderly With Traumatic Acute SubDural Hematoma
Rationale: The rapidly increasing number of elderly (≥ 65 years old) with traumatic brain injury (TBI) is accompanied by substantial medical and economic consequences.
- Trial name
- RESET-ASDH (NCT04648436)
- Testing
- Early neurosurgical hematoma evacuation, Conservative treatment (best medical management)
- Where
- Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Organ Donation, Registration for Deceased Organ Donation
Promoting Organ Donor Registration in Family Physician Offices
This study evaluates the effects of using reception staff to prompt patients by providing a pamphlet and an opportunity to register in the waiting room via a mobile tablet on deceased organ donor registration rates.
- Trial name
- NCT03213171
- Testing
- Reception staff providing handout., Mobile Tablet (e.g. iPad)
- Where
- 2 sites in Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
HPV Vaccine Acceptability
Impact of a School- and Primary Care-based Multicomponent Intervention on HPV Vaccination Acceptability
This study aims at evaluating the effectiveness, efficiency and implementation of a multicomponent intervention (components being applied in combination or alone) on the acceptability of HPV vaccine among French adolescents…
- Trial name
- PrevHPV (NCT04945655)
- Testing
- Adolescents and parents' education and motivation at school (component 1), General practitioners' training (component 2), Access to vaccination at school (component 3)
- Where
- France
- Volunteers
- 30,739 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Nurse-led Supportive Care
Effect of Nurse-led Supportive Care on Caregiver Burden and Well-being
Breast cancer is the most common type of cancer in women with a high mortality rate in the world. Women may experience many different physiological and psychological symptoms (such as pain, nausea-vomiting, fatigue, stress…
- Trial name
- NCT05470543
- Testing
- Nurse-led supportive care
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University